List of works - Isabelle Bernard

A Natural Variant of the Signaling Molecule Vav1 Enhances Susceptibility to Myasthenia Gravis and Influences the T Cell Receptor Repertoire

scientific article published on 25 October 2018

A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

scientific article

A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

scientific article published on 01 December 2009

A dominant role for the thymus and MHC genes in determining the peripheral CD4/CD8 T cell ratio in the rat

scientific article published on 01 September 1999

A higher risk of acute rejection of human kidney allografts can be predicted from the level of CD45RC expressed by the recipients' CD8 T cells

scientific article

A spontaneous mutation of the rat Themis gene leads to impaired function of regulatory T cells linked to inflammatory bowel disease

scientific article

Alloreactive CD4 T lymphocytes responsible for acute and chronic graft-versus-host disease are contained within the CD45RChigh but not the CD45RClow subset.

scientific article published in February 2004

An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development.

scientific article published on 10 July 2015

CD45RC isoform expression identifies functionally distinct T cell subsets differentially distributed between healthy individuals and AAV patients

scientific article

Cellular and genetic factors involved in the difference between Brown Norway and Lewis rats to develop respectively type-2 and type-1 immune-mediated diseases.

scientific article

Experimental autoimmune myasthenia gravis may occur in the context of a polarized Th1- or Th2-type immune response in rats

scientific article published on 01 June 1999

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes.

scientific article published on 11 October 2016

Functional and genetic analysis of two CD8 T cell subsets defined by the level of CD45RC expression in the rat

scientific article published on 01 September 2004

Genetic control of HgCl2-induced IgE and autoimmunity by a 117-kb interval on rat chromosome 9 through CD4 CD45RChigh T cells ⬇️

scientific article published on April 25, 2013

Genomics studies of immune-mediated diseases using the BN-LEW rat model.

scientific article published on January 2010

Human lymphocytes shed a soluble form of CD21 (the C3dg/Epstein-Barr virus receptor, CR2) that binds iC3b and CD23

scientific article

Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation.

scientific article

Non-MHC determined resistance of Brown-Norway rats to develop experimental allergic encephalomyelitis is mediated by the endogenous production of transforming growth factor-beta

scientific article published on 01 May 1999

Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

scientific article published on 14 September 2017

Oral tolerance failure upon neonatal gut colonization with Escherichia coli producing the genotoxin colibactin

scientific article published on 30 March 2015

Polarization toward the T-helper(Th)1 type immune response is not required for rat experimental autoimmune myasthenia gravis

scientific article published on 01 May 1999

Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function

scientific article published on 3 April 2017

Role of IFNγ in Allograft Tolerance Mediated by CD4+CD25+Regulatory T Cells by Induction of IDO in Endothelial Cells

scientific article published on 14 September 2007

The CD8 T cell compartment plays a dominant role in the deficiency of Brown-Norway rats to mount a proper type 1 immune response.

scientific article

The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4+ T cells

scientific article published on 10 July 2018

The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development

scientific article

Transforming growth factor beta (TGF-beta)-dependent inhibition of T helper cell 2 (Th2)-induced autoimmunity by self-major histocompatibility complex (MHC) class II-specific, regulatory CD4(+) T cell lines.

scientific article

VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis

scientific article

List of works by Isabelle Bernard

A Natural Variant of the Signaling Molecule Vav1 Enhances Susceptibility to Myasthenia Gravis and Influences the T Cell Receptor Repertoire

A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

A dominant role for the thymus and MHC genes in determining the peripheral CD4/CD8 T cell ratio in the rat

A higher risk of acute rejection of human kidney allografts can be predicted from the level of CD45RC expressed by the recipients' CD8 T cells

A spontaneous mutation of the rat Themis gene leads to impaired function of regulatory T cells linked to inflammatory bowel disease

Alloreactive CD4 T lymphocytes responsible for acute and chronic graft-versus-host disease are contained within the CD45RChigh but not the CD45RClow subset.

An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development.

CD45RC isoform expression identifies functionally distinct T cell subsets differentially distributed between healthy individuals and AAV patients

Cellular and genetic factors involved in the difference between Brown Norway and Lewis rats to develop respectively type-2 and type-1 immune-mediated diseases.

Experimental autoimmune myasthenia gravis may occur in the context of a polarized Th1- or Th2-type immune response in rats

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes.

Functional and genetic analysis of two CD8 T cell subsets defined by the level of CD45RC expression in the rat

Genetic control of HgCl2-induced IgE and autoimmunity by a 117-kb interval on rat chromosome 9 through CD4 CD45RChigh T cells ⬇️

Genomics studies of immune-mediated diseases using the BN-LEW rat model.

Human lymphocytes shed a soluble form of CD21 (the C3dg/Epstein-Barr virus receptor, CR2) that binds iC3b and CD23

Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation.

Non-MHC determined resistance of Brown-Norway rats to develop experimental allergic encephalomyelitis is mediated by the endogenous production of transforming growth factor-beta

Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

Oral tolerance failure upon neonatal gut colonization with Escherichia coli producing the genotoxin colibactin

Polarization toward the T-helper(Th)1 type immune response is not required for rat experimental autoimmune myasthenia gravis

Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function

Role of IFNγ in Allograft Tolerance Mediated by CD4+CD25+Regulatory T Cells by Induction of IDO in Endothelial Cells

The CD8 T cell compartment plays a dominant role in the deficiency of Brown-Norway rats to mount a proper type 1 immune response.

The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4+ T cells

The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development

Transforming growth factor beta (TGF-beta)-dependent inhibition of T helper cell 2 (Th2)-induced autoimmunity by self-major histocompatibility complex (MHC) class II-specific, regulatory CD4(+) T cell lines.

VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis