List of works - Katherine A Donovan

Acute pharmacological degradation of Helios destabilizes regulatory T cells

scientific article published on 25 May 2021

Bruton tyrosine kinase degradation as a therapeutic strategy for cancer

scientific article published on 13 December 2018

Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK).

scientific article published on 16 April 2018

Comparing the Conformational Stability of Pyruvate Kinase in the Gas Phase and in Solution

scientific article published on 17 January 2020

Conformational Dynamics and Allostery in Pyruvate Kinase.

scientific article

Continuous evolution of compact protein degradation tags regulated by selective molecular glues

scientific article published on 14 March 2024

Development and Characterization of a Wee1 Kinase Degrader

scientific article published on 14 November 2019

Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6

scientific article published on 29 March 2019

Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

scientific article published on 16 December 2019

ER stress signaling promotes the survival of cancer 'persister cells' tolerant to EGFR tyrosine kinase inhibitors

scientific article published on 19 December 2017

Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

scientific article published on 23 October 2017

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

scientific article published on 26 December 2019

Genomic and Biochemical Analysis of the Diaminopimelate and Lysine Biosynthesis Pathway in Verrucomicrobium spinosum: Identification and Partial Characterization of L,L-Diaminopimelate Aminotransferase and UDP-N-Acetylmuramoylalanyl-D-glutamyl-2,6-m

scientific article

Grappling with anisotropic data, pseudo-merohedral twinning and pseudo-translational noncrystallographic symmetry: a case study involving pyruvate kinase.

scientific article

Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML

scientific article published on 27 December 2018

Plasticity in binding confers selectivity in ligand-induced protein degradation

scientific article published on 11 June 2018

Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations

scientific article published on 01 August 2019

Small-molecule-induced polymerization triggers degradation of BCL6

scientific article published on 18 November 2020

Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15

scientific article published on 04 November 2019

Structure-function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control

scientific article published on 08 April 2019

TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma

scientific article published on 29 July 2021

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

scientific article published on 25 March 2019

Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome

scientific article published on 01 August 2018

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

scientific article published on 03 June 2020

The lid domain is important, but not essential, for catalysis of Escherichia coli pyruvate kinase

scientific article published on 25 September 2020

The purification, crystallization and preliminary X-ray diffraction analysis of two isoforms of meso-diaminopimelate decarboxylase from Arabidopsis thaliana

scientific article

pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBN ubiquitin ligase

scientific article published on 22 May 2017

List of works by Katherine A Donovan

Acute pharmacological degradation of Helios destabilizes regulatory T cells

Bruton tyrosine kinase degradation as a therapeutic strategy for cancer

Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK).

Comparing the Conformational Stability of Pyruvate Kinase in the Gas Phase and in Solution

Conformational Dynamics and Allostery in Pyruvate Kinase.

Continuous evolution of compact protein degradation tags regulated by selective molecular glues

Development and Characterization of a Wee1 Kinase Degrader

Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6

Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

ER stress signaling promotes the survival of cancer 'persister cells' tolerant to EGFR tyrosine kinase inhibitors

Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

Genomic and Biochemical Analysis of the Diaminopimelate and Lysine Biosynthesis Pathway in Verrucomicrobium spinosum: Identification and Partial Characterization of L,L-Diaminopimelate Aminotransferase and UDP-N-Acetylmuramoylalanyl-D-glutamyl-2,6-m

Grappling with anisotropic data, pseudo-merohedral twinning and pseudo-translational noncrystallographic symmetry: a case study involving pyruvate kinase.

Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML

Plasticity in binding confers selectivity in ligand-induced protein degradation

Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations

Small-molecule-induced polymerization triggers degradation of BCL6

Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15

Structure-function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control

TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

The lid domain is important, but not essential, for catalysis of Escherichia coli pyruvate kinase

The purification, crystallization and preliminary X-ray diffraction analysis of two isoforms of meso-diaminopimelate decarboxylase from Arabidopsis thaliana

pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBN ubiquitin ligase