List of works - Emiel A M Janssen

A Monotonous Population of Elongated Cells (MPECs) in Colorectal Adenoma Indicates a High Risk of Metachronous Cancer

A Quantitative Centrosomal Amplification Score Predicts Local Recurrence of Ductal Carcinoma In Situ

scientific article published on 14 January 2020

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells

scientific article published on 23 July 2018

A protein profile study to discriminate CIN lesions from normal cervical epithelium.

scientific article

Adenomyoepitheliomatous lesions of the mammary glands in transgenic mice with targeted PLAG1 overexpression

scientific article

Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells

scientific article published on 08 March 2017

Androgen receptor determination in breast cancer: a comparison of the dextran-coated charcoal method and quantitative immunohistochemical analysis

scientific article published on 01 July 2008

Apolipoprotein D expression does not predict breast cancer recurrence among tamoxifen-treated patients

scientific article

Apolipoprotein D predicts adverse outcome in women >or=70 years with operable breast cancer

scientific article published on 11 March 2008

Assessing the prognostic value of PAX2 and PTEN in endometrial carcinogenesis

scientific article published on 01 December 2018

Biologic profiling of lymph node negative breast cancers by means of microRNA expression ⬇️

scientific article published on September 3, 2010

Biomarkers and microsatellite instability analysis of curettings can predict the behavior of FIGO stage I endometrial endometrioid adenocarcinoma ⬇️

scientific article published on May 6, 2011

Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients.

scientific article published in January 2007

Cervical intraepithelial neoplasia grade 3 lesions can regress

scientific article published on December 2007

Co-expression of estrogen receptor alpha and Apolipoprotein D in node positive operable breast cancer--possible relevance for survival and effects of adjuvant tamoxifen in postmenopausal patients

scientific article

Combined p53 and retinoblastoma protein detection identifies persistent and regressive cervical high-grade squamous intraepithelial lesions

scientific article published in August 2005

Comparing the prognostic value of PTEN and Akt expression with the Mitotic Activity Index in adjuvant chemotherapy-treated node-negative breast cancer patients aged <55 years.

scientific article

Comparison of a PNA clamp PCR and an ARMS/Scorpion PCR assay for the detection of K-ras mutations

scientific article published in March 2012

Comparison of apolipoprotein D determination methods in breast cancer

scientific article published on 01 March 2008

Comparison of different commercial methods for HPV detection in follow-up cytology after ASCUS/LSIL, prediction of CIN2-3 in follow up biopsies and spontaneous regression of CIN2-3

scientific article published on 10 August 2011

Comparison of the effect of different techniques for measurement of Ki67 proliferation on reproducibility and prognosis prediction accuracy in breast cancer ⬇️

scientific article published on September 11, 2012

Consistent Condom Use Increases the Regression Rate of Cervical Intraepithelial Neoplasia 2–3 ⬇️

scientific article published on September 13, 2012

Correlation of grade of urothelial cell carcinomas and DNA histogram features assessed by flow cytometry and automated image cytometry.

scientific article

D2-40/p63 defined lymph vessel invasion has additional prognostic value in highly proliferating operable node negative breast cancer patients ⬇️

scientific article published on February 11, 2011

DNA cytometric features in biopsies of TaT1 urothelial cell cancer predict recurrence and stage progression more accurately than stage, grade, or treatment modality

scientific article published on 01 June 2003

Detection of disseminated tumor cells in bone marrow predict late recurrences in operable breast cancer patients

scientific article published on 21 November 2019

Diagnostic and prognostic morphometric features in WHO2003 invasive endometrial stromal tumours ⬇️

scientific article published on 01 April 2013

Digital Image Analysis of Ki-67 Stained Tissue Microarrays and Recurrence in Tamoxifen-Treated Breast Cancer Patients

scientific article published on 20 July 2020

Digital image analysis improves the quality of subjective HER-2 expression scoring in breast cancer

scientific article

Distinct Gene Expression Profiles of Matched Primary and Metastatic Triple-Negative Breast Cancers

scientific article published on 16 May 2022

Dynamic behavioural interpretation of cervical intraepithelial neoplasia with molecular biomarkers

scientific article published on 5 May 2006

Emerging concepts of apolipoprotein D with possible implications for breast cancer.

scientific article

Evaluation of 5 different labeled polymer immunohistochemical detection systems

scientific article

Evaluation of MIB-1-positive cell clusters as a diagnostic marker for cervical intraepithelial neoplasia

scientific article published on 01 November 2002

Expression profiling and intracellular localization studies of the novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an essential role in gastro-intestinal epithelium and a potential clinical application in colorectal cancer diagnostics

scientific article published on 7 February 2018

From SELDI-TOF MS to protein identification by on-chip elution

scientific article published on 23 July 2011

Further testing of morphometric grading in T(A,1) urothelial carcinomas of the urinary bladder and the additional value of p53 immunoquantitation

scientific article published on 01 April 2002

Gain of Chromosomal Region 3q26 as a Prognostic Biomarker for High-Grade Cervical Intraepithelial Neoplasia: Literature Overview and Pilot Study

scientific article published on 25 October 2018

Genomics and proteomics--the way forward

scientific article

HPV tests at Stavanger University Hospital ⬇️

scientific article published on November 18, 2010

High frequency microsatellite instability has a prognostic value in endometrial endometrioid adenocarcinoma, but only in FIGO stage 1 cases

scientific article published on 6 May 2011

High frequency microsatellite instability has a prognostic value in endometrial endometrioid adenocarcinoma, but only in FIGO stage 1 cases ⬇️

scientific article published on January 1, 2010

In Patients Younger Than Age 55 Years With Lymph Node–Negative Breast Cancer, Proliferation by Mitotic Activity Index Is Prognostically Superior to Adjuvant! ⬇️

scientific article published on December 28, 2010

In lymph node-negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumour diameter, and oestrogen receptor

scientific article

Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients ─ a randomized trial

scientific article published on 08 November 2019

Interaction of epithelial biomarkers, local immune response and condom use in cervical intraepithelial neoplasia 2-3 regression

scientific article

Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model.

scientific article

LOH at 1p31 (ARHI) and proliferation in lymph node-negative breast cancer.

scientific article

Lack of PTEN expression in endometrial intraepithelial neoplasia is correlated with cancer progression

scientific article published on 01 May 2005

Local immune response in the microenvironment of CIN2-3 with and without spontaneous regression

scientific article

Low Protein A20 in Minor Salivary Glands is Associated with Lymphoma in Primary Sjögren's Syndrome

scientific article published on 18 December 2015

Low p53 and retinoblastoma protein expression in cervical intraepithelial neoplasia grade 3 lesions is associated with coexistent adenocarcinoma in situ

scientific article published on 30 January 2008

Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study

scientific article published on 04 December 2019

Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.

scientific article

MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers

scientific article published on 05 May 2020

Microsatellite instability and DNA ploidy in colorectal cancer: potential implications for patients undergoing systematic surveillance after resection.

scientific article

Microsatellite instability in colorectal cancer

Mitotic activity and bone marrow micrometastases have independent prognostic value in node positive breast cancer patients

scientific article published on 08 April 2011

Mitotic activity index and CD25+ lymphocytes predict risk of stage progression in non-muscle invasive bladder cancer

scientific article published on 02 June 2020

Molecular biomarkers in endometrial hyperplasias predict cancer progression ⬇️

scientific article published on February 16, 2011

Multivariate prognostic evaluation of the mitotic activity index and fibrotic focus in node-negative invasive breast cancers

scientific article published on 01 September 2005

Panoptic View of Prognostic Models for Personalized Breast Cancer Management

scientific article published on 07 September 2019

Phosphohistone H3 expression has much stronger prognostic value than classical prognosticators in invasive lymph node-negative breast cancer patients less than 55 years of age.

scientific article

Prediction of spontaneous regression of cervical intraepithelial neoplasia lesions grades 2 and 3 by proteomic analysis

scientific article

Predictive testing of early CIN behaviour by molecular biomarkers.

scientific article

Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study

scientific article published on 17 July 2019

Prognostic comparison of proliferation markers and World Health Organization 1973/2004 grades in urothelial carcinomas of the urinary bladder

scientific article published on 26 March 2014

Prognostic comparison of the proliferation markers (mitotic activity index, phosphohistone H3, Ki67), steroid receptors, HER2, high molecular weight cytokeratins and classical prognostic factors in T₁₋₂N₀M₀ breast cancer

scientific article published on April 1, 2013

Prognostic differences of World Health Organization-assessed mitotic activity index and mitotic impression by quick scanning in invasive ductal breast cancer patients younger than 55 years

scientific article published on 4 March 2008

Prognostic relevance of androgen receptor detection in operable breast cancer

scientific article

Prognostic value and reproducibility of different microscopic characteristics in the WHO grading systems for pTa and pT1 urinary bladder urothelial carcinomas

scientific article published on 14 August 2019

Prognostic value of gene signatures and proliferation in lymph-node-negative breast cancer

scientific article

Proliferation accurately identifies the high-risk patients among small, low-grade, lymph node-negative invasive breast cancers

scientific article published on 27 November 2007

Proliferation is the strongest prognosticator in node-negative breast cancer: significance, error sources, alternatives and comparison with molecular prognostic markers

scientific article

Proliferation markers and DNA content analysis in urinary bladder TaT1 urothelial cell carcinomas: identification of subgroups with low and high stage progression risks

scientific article published on June 2003

Prospective multicenter comparison of proliferation and other prognostic factors in lymph node negative lobular invasive breast cancer

scientific article published on 01 July 2009

Prospective multicenter validation of the independent prognostic value of the mitotic activity index in lymph node-negative breast cancer patients younger than 55 years

scientific article published in September 2005

Protein Conformational Changes in Breast Cancer Sera Using Infrared Spectroscopic Analysis

scientific article published on 27 June 2020

Quality assurance of human papillomavirus (HPV) testing in the implementation of HPV primary screening in Norway: an inter-laboratory reproducibility study.

scientific article

Quantitative molecular parameters to identify low-risk and high-risk early CIN lesions: role of markers of proliferative activity and differentiation and Rb availability

scientific article published on April 2004

Reproducibility and prognostic value of WHO1973 and WHO2004 grading systems in TaT1 urothelial carcinoma of the urinary bladder

scientific article published on 07 January 2014

Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients

scientific article published on 28 November 2017

Success predictors of adjuvant chemotherapy in node-negative breast cancer patients under 55 years.

scientific article

The Role of MicroRNAs as Predictors of Response to Tamoxifen Treatment in Breast Cancer Patients

scientific article

The impact of epithelial biomarkers, local immune response and human papillomavirus genotype in the regression of cervical intraepithelial neoplasia grades 2–3 ⬇️

scientific article published on 01 April 2011

The prognostic and predictive value of syntactic structure analysis in serous carcinoma of the ovary

scientific article published on April 2008

The prognostic value of MARCKS-like 1 in lymph node-negative breast cancer ⬇️

scientific article published on 08 July 2012

The prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancer

scientific article

The prognostic value of molecular biomarkers in tissue removed by curettage from FIGO stage 1 and 2 endometrioid type endometrial cancer

scientific article published on 30 October 2008

The prognostic value of proliferation in lymph-node-negative breast cancer patients is age dependent

scientific article published on 15 November 2006

The prognostic value of the orphan nuclear receptor DAX-1 (NROB1) in node-negative breast cancer

scientific article published on February 1, 2011

The prognostic value of the proliferation marker phosphohistone H3 (PPH3) in luminal, basal-like and triple negative phenotype invasive lymph node-negative breast cancer

scientific article published in January 2009

Validating the prognostic value of proliferation measured by Phosphohistone H3 (PPH3) in invasive lymph node-negative breast cancer patients less than 71 years of age.

scientific article

Validation of Expression Patterns for Nine miRNAs in 204 Lymph-Node Negative Breast Cancers ⬇️

scientific article published on November 7, 2012

Validation study of MARCKSL1 as a prognostic factor in lymph node-negative breast cancer patients

miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer

scientific article published on 10 February 2021

List of works by Emiel A M Janssen

A Monotonous Population of Elongated Cells (MPECs) in Colorectal Adenoma Indicates a High Risk of Metachronous Cancer

A Quantitative Centrosomal Amplification Score Predicts Local Recurrence of Ductal Carcinoma In Situ

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells

A protein profile study to discriminate CIN lesions from normal cervical epithelium.

Adenomyoepitheliomatous lesions of the mammary glands in transgenic mice with targeted PLAG1 overexpression

Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells

Androgen receptor determination in breast cancer: a comparison of the dextran-coated charcoal method and quantitative immunohistochemical analysis

Apolipoprotein D expression does not predict breast cancer recurrence among tamoxifen-treated patients

Apolipoprotein D predicts adverse outcome in women >or=70 years with operable breast cancer

Assessing the prognostic value of PAX2 and PTEN in endometrial carcinogenesis

Biologic profiling of lymph node negative breast cancers by means of microRNA expression ⬇️

Biomarkers and microsatellite instability analysis of curettings can predict the behavior of FIGO stage I endometrial endometrioid adenocarcinoma ⬇️

Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients.

Cervical intraepithelial neoplasia grade 3 lesions can regress

Co-expression of estrogen receptor alpha and Apolipoprotein D in node positive operable breast cancer--possible relevance for survival and effects of adjuvant tamoxifen in postmenopausal patients

Combined p53 and retinoblastoma protein detection identifies persistent and regressive cervical high-grade squamous intraepithelial lesions

Comparing the prognostic value of PTEN and Akt expression with the Mitotic Activity Index in adjuvant chemotherapy-treated node-negative breast cancer patients aged <55 years.

Comparison of a PNA clamp PCR and an ARMS/Scorpion PCR assay for the detection of K-ras mutations

Comparison of apolipoprotein D determination methods in breast cancer

Comparison of different commercial methods for HPV detection in follow-up cytology after ASCUS/LSIL, prediction of CIN2-3 in follow up biopsies and spontaneous regression of CIN2-3

Comparison of the effect of different techniques for measurement of Ki67 proliferation on reproducibility and prognosis prediction accuracy in breast cancer ⬇️

Consistent Condom Use Increases the Regression Rate of Cervical Intraepithelial Neoplasia 2–3 ⬇️

Correlation of grade of urothelial cell carcinomas and DNA histogram features assessed by flow cytometry and automated image cytometry.

D2-40/p63 defined lymph vessel invasion has additional prognostic value in highly proliferating operable node negative breast cancer patients ⬇️

DNA cytometric features in biopsies of TaT1 urothelial cell cancer predict recurrence and stage progression more accurately than stage, grade, or treatment modality

Detection of disseminated tumor cells in bone marrow predict late recurrences in operable breast cancer patients

Diagnostic and prognostic morphometric features in WHO2003 invasive endometrial stromal tumours ⬇️

Digital Image Analysis of Ki-67 Stained Tissue Microarrays and Recurrence in Tamoxifen-Treated Breast Cancer Patients

Digital image analysis improves the quality of subjective HER-2 expression scoring in breast cancer

Distinct Gene Expression Profiles of Matched Primary and Metastatic Triple-Negative Breast Cancers

Dynamic behavioural interpretation of cervical intraepithelial neoplasia with molecular biomarkers

Emerging concepts of apolipoprotein D with possible implications for breast cancer.

Evaluation of 5 different labeled polymer immunohistochemical detection systems

Evaluation of MIB-1-positive cell clusters as a diagnostic marker for cervical intraepithelial neoplasia

Expression profiling and intracellular localization studies of the novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an essential role in gastro-intestinal epithelium and a potential clinical application in colorectal cancer diagnostics

From SELDI-TOF MS to protein identification by on-chip elution

Further testing of morphometric grading in T(A,1) urothelial carcinomas of the urinary bladder and the additional value of p53 immunoquantitation

Gain of Chromosomal Region 3q26 as a Prognostic Biomarker for High-Grade Cervical Intraepithelial Neoplasia: Literature Overview and Pilot Study

Genomics and proteomics--the way forward

HPV tests at Stavanger University Hospital ⬇️

High frequency microsatellite instability has a prognostic value in endometrial endometrioid adenocarcinoma, but only in FIGO stage 1 cases

High frequency microsatellite instability has a prognostic value in endometrial endometrioid adenocarcinoma, but only in FIGO stage 1 cases ⬇️

In Patients Younger Than Age 55 Years With Lymph Node–Negative Breast Cancer, Proliferation by Mitotic Activity Index Is Prognostically Superior to Adjuvant! ⬇️

In lymph node-negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumour diameter, and oestrogen receptor

Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients ─ a randomized trial

Interaction of epithelial biomarkers, local immune response and condom use in cervical intraepithelial neoplasia 2-3 regression

Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model.

LOH at 1p31 (ARHI) and proliferation in lymph node-negative breast cancer.

Lack of PTEN expression in endometrial intraepithelial neoplasia is correlated with cancer progression

Local immune response in the microenvironment of CIN2-3 with and without spontaneous regression

Low Protein A20 in Minor Salivary Glands is Associated with Lymphoma in Primary Sjögren's Syndrome

Low p53 and retinoblastoma protein expression in cervical intraepithelial neoplasia grade 3 lesions is associated with coexistent adenocarcinoma in situ

Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study

Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.

MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers

Microsatellite instability and DNA ploidy in colorectal cancer: potential implications for patients undergoing systematic surveillance after resection.

Microsatellite instability in colorectal cancer

Mitotic activity and bone marrow micrometastases have independent prognostic value in node positive breast cancer patients

Mitotic activity index and CD25+ lymphocytes predict risk of stage progression in non-muscle invasive bladder cancer

Molecular biomarkers in endometrial hyperplasias predict cancer progression ⬇️

Multivariate prognostic evaluation of the mitotic activity index and fibrotic focus in node-negative invasive breast cancers

Panoptic View of Prognostic Models for Personalized Breast Cancer Management

Phosphohistone H3 expression has much stronger prognostic value than classical prognosticators in invasive lymph node-negative breast cancer patients less than 55 years of age.

Prediction of spontaneous regression of cervical intraepithelial neoplasia lesions grades 2 and 3 by proteomic analysis

Predictive testing of early CIN behaviour by molecular biomarkers.

Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study

Prognostic comparison of proliferation markers and World Health Organization 1973/2004 grades in urothelial carcinomas of the urinary bladder

Prognostic comparison of the proliferation markers (mitotic activity index, phosphohistone H3, Ki67), steroid receptors, HER2, high molecular weight cytokeratins and classical prognostic factors in T₁₋₂N₀M₀ breast cancer

Prognostic differences of World Health Organization-assessed mitotic activity index and mitotic impression by quick scanning in invasive ductal breast cancer patients younger than 55 years

Prognostic relevance of androgen receptor detection in operable breast cancer

Prognostic value and reproducibility of different microscopic characteristics in the WHO grading systems for pTa and pT1 urinary bladder urothelial carcinomas

Prognostic value of gene signatures and proliferation in lymph-node-negative breast cancer

Proliferation accurately identifies the high-risk patients among small, low-grade, lymph node-negative invasive breast cancers

Proliferation is the strongest prognosticator in node-negative breast cancer: significance, error sources, alternatives and comparison with molecular prognostic markers

Proliferation markers and DNA content analysis in urinary bladder TaT1 urothelial cell carcinomas: identification of subgroups with low and high stage progression risks

Prospective multicenter comparison of proliferation and other prognostic factors in lymph node negative lobular invasive breast cancer

Prospective multicenter validation of the independent prognostic value of the mitotic activity index in lymph node-negative breast cancer patients younger than 55 years

Protein Conformational Changes in Breast Cancer Sera Using Infrared Spectroscopic Analysis

Quality assurance of human papillomavirus (HPV) testing in the implementation of HPV primary screening in Norway: an inter-laboratory reproducibility study.