List of works - Akira Orimo

Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies ⬇️

scientific article published on 07 May 2019

CD26 expression is attenuated by TGF-β and SDF-1 autocrine signaling on stromal myofibroblasts in human breast cancers

scientific article published on 29 May 2019

Cancer-associated fibroblast migration in non-small cell lung cancers is modulated by increased integrin α11 expression

scientific article published on 25 March 2021

Cancer-associated myofibroblasts possess various factors to promote endometrial tumor progression

scientific article published on 01 October 2001

Carcinoma-associated fibroblasts are a promising therapeutic target.

scientific article published on 31 January 2013

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression.

scientific article published on 24 October 2009

Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells.

scientific article published on August 2013

Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer.

scientific article published on 11 April 2016

Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes

scientific article published on 11 March 2017

Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

scientific article published on 18 October 2016

Differential immunolocalization of estrogen receptor alpha and beta in rat ovary and uterus

scientific article published on 01 February 1999

Efp as a primary estrogen-responsive gene in human breast cancer.

scientific article

Emerging roles of the tumor-associated stroma in promoting tumor metastasis.

scientific article published on May 2012

Estrogen activates telomerase.

scientific article published in December 1999

Experimental generation of carcinoma-associated fibroblasts (CAFs) from human mammary fibroblasts

scientific article published on 25 October 2011

Heterogeneity of stromal fibroblasts in tumors

scientific article published on 01 April 2007

High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor

scientific article published on 14 June 2018

Impaired estrogen sensitivity in bone by inhibiting both estrogen receptor alpha and beta pathways

scientific article published on 01 July 2000

Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state

scientific article published on 01 November 2019

Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.

scientific article published on 12 March 2018

Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth.

scientific article published on 15 May 2017

Molecular cloning of rat efp: expression and regulation in primary osteoblasts

scientific journal article

Molecular cloning of ring finger protein 21 (RNF21)/interferon-responsive finger protein (ifp1), which possesses two RING-B box-coiled coil domains in tandem.

scientific article

Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity

scientific article published on 22 July 2019

Successful germ-line transmission of chimeras generated by coculture aggregation with J1 ES cells and eight-cell embryos

scientific article published on 01 April 1999

The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients

scientific article published on 19 October 2015

The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.

scientific article

The roles of tumor- and metastasis-promoting carcinoma-associated fibroblasts in human carcinomas.

scientific article

Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.

scientific article published on October 1999

List of works by Akira Orimo

Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies ⬇️

CD26 expression is attenuated by TGF-β and SDF-1 autocrine signaling on stromal myofibroblasts in human breast cancers

Cancer-associated fibroblast migration in non-small cell lung cancers is modulated by increased integrin α11 expression

Cancer-associated myofibroblasts possess various factors to promote endometrial tumor progression

Carcinoma-associated fibroblasts are a promising therapeutic target.

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression.

Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells.

Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer.

Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes

Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

Differential immunolocalization of estrogen receptor alpha and beta in rat ovary and uterus

Efp as a primary estrogen-responsive gene in human breast cancer.

Emerging roles of the tumor-associated stroma in promoting tumor metastasis.

Estrogen activates telomerase.

Experimental generation of carcinoma-associated fibroblasts (CAFs) from human mammary fibroblasts

Heterogeneity of stromal fibroblasts in tumors

High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor

Impaired estrogen sensitivity in bone by inhibiting both estrogen receptor alpha and beta pathways

Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state

Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.

Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth.

Molecular cloning of rat efp: expression and regulation in primary osteoblasts

Molecular cloning of ring finger protein 21 (RNF21)/interferon-responsive finger protein (ifp1), which possesses two RING-B box-coiled coil domains in tandem.

Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity

Successful germ-line transmission of chimeras generated by coculture aggregation with J1 ES cells and eight-cell embryos

The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients

The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.

The roles of tumor- and metastasis-promoting carcinoma-associated fibroblasts in human carcinomas.

Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.