List of works by Johannes Pieter Albert Baak

'Blind' multicenter evaluation of the prognostic value of DNA image cytometric and morphometric features in invasive breast cancer.

scientific article published in March 1996

A Monotonous Population of Elongated Cells (MPECs) in Colorectal Adenoma Indicates a High Risk of Metachronous Cancer

A comparative study in morphometric grading of transitional cell carcinoma of the urinary bladder.

scientific article published in December 1989

A computer based handbook and atlas of pathology

scientific article published on 01 November 1989

A method for the acquisition of formalized knowledge in pathology.

scientific article published in July 1990

A new and highly sensitive immunohistologic diagnostic criterion for Sjögren's syndrome

scientific article published in October 1989

A protein profile study to discriminate CIN lesions from normal cervical epithelium.

scientific article

Aberrant expression of MUC1 mucin in ductal hyperplasia and ductal carcinoma In situ of the breast

scientific article published on 01 October 1999

Adenocarcinoma in situ of the cervix: an underdiagnosed lesion

scientific article published on 01 August 1981

Adenomyoepitheliomatous lesions of the mammary glands in transgenic mice with targeted PLAG1 overexpression

scientific article

Advanced epithelial ovarian cancer: 1993 consensus statements

scientific article published on January 1993

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

scientific article (publication date: 7 June 2000)

An evaluation of prognostic factors in advanced ovarian cancer

scientific article published on December 1995

An expert system for histological typing and grading of invasive breast cancer. First set up.

scientific article published in June 1992

Analysis by comparative genomic hybridization of epithelial and spindle cell components in sarcomatoid carcinoma and carcinosarcoma: histogenetic aspects

scientific article published on 01 November 1999

Analysis of major histocompatibility complex class I expression on Reed-Sternberg cells in relation to the cytotoxic T-cell response in Epstein-Barr virus-positive and -negative Hodgkin's disease.

scientific article published in May 1996

Analysis of measuring system parameters that influence reproducibility of morphometric assessments with a graphic tablet

scientific article published on 01 May 1988

Androgen receptor determination in breast cancer: a comparison of the dextran-coated charcoal method and quantitative immunohistochemical analysis

scientific article published on 01 July 2008

Apolipoprotein D predicts adverse outcome in women >or=70 years with operable breast cancer

scientific article published on 11 March 2008

Architectural and nuclear morphometrical features together are more important prognosticators in endometrial hyperplasias than nuclear morphometrical features alone ⬇️

scientific article published on 01 April 1988

Assessing the prognostic value of PAX2 and PTEN in endometrial carcinogenesis

scientific article published on 01 December 2018

Assessment of chromosomal gains and losses in oral squamous cell carcinoma by comparative genomic hybridisation

scientific article published on 01 November 1997

Assessment of the risk on endometrial cancer in hyperplasia, by means of morphological and morphometrical features

scientific article published on October 1, 1992

At convenience and systematic random sampling: effects on the prognostic value of nuclear area assessments in breast cancer patients ⬇️

scientific article published on 01 January 1995

Automated estimation of epithelial volume in breast cancer sections. A comparison with the image processing steps applied to gynecologic tumors

scientific article

Automated selection of the most epithelium-rich areas in gynecologic tumor sections

scientific article published on 01 December 1991

B lymphocytes in the guinea pig thymus are specifically localized in the central area ⬇️

scientific article published on August 1, 1976

Balance of cell proliferation and apoptosis in breast carcinogenesis.

scientific article published in November 1999

Barrett's adenocarcinomas resemble adenocarcinomas of the gastric cardia in terms of chromosomal copy number changes, but relate to squamous cell carcinomas of the distal oesophagus with respect to the presence of high-level amplifications.

scientific article

Benign endometrial hyperplasia sequence and endometrial intraepithelial neoplasia

scientific article published on April 2007

Biologic profiling of lymph node negative breast cancers by means of microRNA expression ⬇️

scientific article published on September 3, 2010

Biomarkers and microsatellite instability analysis of curettings can predict the behavior of FIGO stage I endometrial endometrioid adenocarcinoma.

scientific article

Biopsy histomorphometry predicts uterine myoinvasion by endometrial carcinoma: a Gynecologic Oncology Group study

scientific article

Borderline malignancy of the ovary and controlled hyperstimulation, a report of 2 cases

scientific article published on 01 January 1992

Borderline ovarian tumors

scientific article published on 01 July 1998

Bronchopulmonary carcinoids and regional lymph node metastases. A quantitative pathologic investigation ⬇️

scientific article published on July 1, 1988

Can proliferation biomarkers reliably predict recurrence in World Health Organization 2003 defined endometrial stromal sarcoma, low grade?

scientific article

Carcinoembryonic antigen expression and peanut agglutinin binding in primary breast cancer and lymph node metastases; lack of correlation with clinical, histopathological, biochemical and morphometric features

Cell cycle analysis of 932 flow cytometric DNA histograms of fresh frozen breast carcinoma material. Correlations between flow cytometric, clinical, and pathologic variables. MMMCP Collaborative Group. Multicenter Morphometric Mammary Carcinoma Proj

scientific article published on 01 June 1996

Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients.

scientific article published in January 2007

Centromeric chromosomal translocations show tissue-specific differences between squamous cell carcinomas and adenocarcinomas.

scientific article published on February 2005

Cervical intraepithelial neoplasia grade 3 lesions can regress

scientific article published on December 2007

Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumour cells

scientific article

Chromosomal instability in flat adenomas and carcinomas of the colon.

scientific article published in March 2005

Classification of colorectal adenomas with quantitative pathology. Evaluation of morphometry, stereology, mitotic counts and syntactic structure analysis

scientific article published on 01 December 1995

Clinical decision making in Barrett's oesophagus can be supported by computerized immunoquantitation and morphometry of features associated with proliferation and differentiation.

scientific article published in February 1998

Co-expression of estrogen receptor alpha and Apolipoprotein D in node positive operable breast cancer--possible relevance for survival and effects of adjuvant tamoxifen in postmenopausal patients

scientific article

Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability

scientific article published on 01 October 2002

Combined p53 and retinoblastoma protein detection identifies persistent and regressive cervical high-grade squamous intraepithelial lesions

scientific article published in August 2005

Comparative evaluation of diagnostic methods in ovarian carcinoma with emphasis on CT and MRI.

scientific article published in February 1994

Comparative genomic hybridisation

scientific article

Comparative genomic hybridisation divides retinoblastomas into a high and a low level chromosomal instability group

scientific article published on January 2003

Comparative genomic hybridization of microdissected familial ovarian carcinoma: two deleted regions on chromosome 15q not previously identified in sporadic ovarian carcinoma.

scientific article

Comparative genomic hybridization: a new tool in cancer pathology

scientific article published on April 1996

Comparative long-term prognostic value of quantitative HER-2/neu protein expression, DNA ploidy, and morphometric and clinical features in paraffin-embedded invasive breast cancer

scientific article published on February 1, 1991

Comparing subjective and digital image analysis HER2/neu expression scores with conventional and modified FISH scores in breast cancer

scientific article published on 5 April 2007

Comparing the prognostic value of PTEN and Akt expression with the Mitotic Activity Index in adjuvant chemotherapy-treated node-negative breast cancer patients aged <55 years.

scientific article

Comparison of apolipoprotein D determination methods in breast cancer

scientific article published on 01 March 2008

Comparison of different commercial methods for HPV detection in follow-up cytology after ASCUS/LSIL, prediction of CIN2-3 in follow up biopsies and spontaneous regression of CIN2-3

scientific article published on 10 August 2011

Comparison of extent of disease and morphometric and DNA flow cytometric prognostic factors in invasive ductal breast cancer

scientific article

Comparison of five cell cycle analysis models applied to 1414 flow cytometric DNA histograms of fresh frozen breast cancer

scientific article published on 01 February 1997

Comparison of light microscopic grading and morphometric features in cytological breast cancer specimens

scientific article published on 01 November 1989

Comparison of quantitative and classic prognosticators in urinary bladder carcinoma. A multivariate analysis of DNA flow cytometric, nuclear morphometric and clinicopathological features

scientific article published in January 1989

Comparison of the effect of different techniques for measurement of Ki67 proliferation on reproducibility and prognosis prediction accuracy in breast cancer

scientific article published on 11 September 2012

Comparison of the prognostic value of four methods to assess mitotic activity in 186 invasive breast cancer patients: classical and random mitotic activity assessments with correction for volume percentage of epithelium

scientific article published on 01 October 1995

Comprehensive Cancer Centre Amsterdam Barrett Advisory Committee: first results

scientific article published on 01 January 2001

Computation of preoperative diagnosis probability for follicular adenoma and carcinoma of the thyroid on aspiration smears.

scientific article published in March 1982

Computer assisted efficiency testing of different sampling methods for selective nuclear graphic tablet morphometry

scientific article

Computer-aided application of quantitative microscopy in diagnostic pathology

scientific article published on January 1982

Computer-based morphometric image analysis of endometrial hyperplasia

scientific article published on 01 February 2000

Computerised morphometrical analysis in endometrial hyperplasia for the prediction of cancer development. A long-term retrospective study from northern Norway

scientific article

Computerized quantitative pathology for the grading of dysplasia in surveillance biopsies of Barrett's oesophagus

scientific article published on February 2000

Concerted overexpression of the genes encoding p21 and cyclin D1 is associated with growth inhibition and differentiation in various carcinomas

scientific article published on April 1999

Confirmation of the prognostic value of the ECPI-1 score (myometrial invasion, DNA-ploidy and mean shortest nuclear axis) in FIGO stage I endometrial cancer patients with long follow-up

scientific article published on 01 March 1995

Confocal DNA cytometry: a contour-based segmentation algorithm for automated three-dimensional image segmentation

scientific article

Confocal laser microscopy and image processing for three-dimensional microscopy: technical principles and an application to breast cancer

scientific article published on January 1994

Consistent condom use increases the regression rate of cervical intraepithelial neoplasia 2-3.

scientific article

Construction of the diagnostic encyclopedia workstation. Computerizing pathology for the pathologist.

scientific article published in December 1989

Correlation between morphometrical parameters and disease-free survival in ductal breast cancer treated only by surgery

scientific article published on January 1986

Correlation of cyclin D1 and Rb gene expression with apoptosis in invasive breast cancer

scientific article published on February 1998

Correlation of grade of urothelial cell carcinomas and DNA histogram features assessed by flow cytometry and automated image cytometry.

scientific article

Counting mitoses by image processing in Feulgen stained breast cancer sections: the influence of resolution

scientific article published in June 1997

Counting of apoptotic cells: a methodological study in invasive breast cancer

scientific article

Cyclin D1 expression in invasive breast cancer. Correlations and prognostic value.

scientific article published on February 1997

Cytogenetic characteristics of oral squamous cell carcinomas in Fanconi anemia

scientific article published on 01 January 2001

Cytomorphometry. A methodologic study of preparation techniques, selection methods and sample sizes

Cytonuclear morphometry in the assessment of dysplasia in colorectal adenomatous polyps. A pilot study

scientific article published on 01 February 1992

D2-40/p63 defined lymph vessel invasion has additional prognostic value in highly proliferating operable node negative breast cancer patients

scientific article published on 11 February 2011

DNA cytometric features in biopsies of TaT1 urothelial cell cancer predict recurrence and stage progression more accurately than stage, grade, or treatment modality

scientific article published on 01 June 2003

DNA measurement errors with a scanning microdensitometer in cytologic and histologic samples of breast cancers

scientific article published on 01 April 1991

DNA ploidy and nuclear morphometry for the classification of dysplastic nevi

scientific article published on 01 October 1999

DNA ploidy status in 84 ocular melanomas: a study of DNA quantitation in ocular melanomas by flow cytometry and automatic and interactive static image analysis

scientific article published on 01 January 1995

DNA quantitation of distal bile duct carcinoma measured by image and flow cytometry

scientific article published on 01 August 1999

Data processing and analysis in the Multicenter Morphometric Mammary Carcinoma Project (MMMCP).

scientific article

Deoxyribonucleic acid ploidy studies in choroidal melanomas

scientific article published on 01 March 1993

Design of the diagnostic encyclopedia workstation (DEW)

scientific article published on 01 January 1990

Detection of chromosomal abnormalities by comparative genomic hybridization

scientific article

Development and use of a rule-based pathology expert consultation system

scientific article published on 01 June 1988

Diagnostic and prognostic morphometric features in WHO2003 invasive endometrial stromal tumours

scientific article published on 01 April 2013

Digital image analysis improves the quality of subjective HER-2 expression scoring in breast cancer

scientific article

Disagreement of histopathological diagnosis of different pathologists in ovarian tumors-with some theoretical considerations

scientific article published on 01 February 1982

Discriminant analysis, exemplified with quantitative features of endometrium ⬇️

scientific article published on January 1, 1977

Discrimination between benign and malignant melanocytic skin lesions by multivariate analysis, quantitative S-100 immunohistochemistry, nuclear morphometry and DNA cytometry

scientific article published on 01 August 1999

Discrimination of hyperplasia and carcinoma of the endometrium by quantitative microscopy--a feasibility study

scientific article published on 01 January 1981

Distinct chromosomal aberrations in Epstein-Barr virus-carrying gastric carcinomas tested by comparative genomic hybridization.

scientific article published in September 2001

Dynamic behavioural interpretation of cervical intraepithelial neoplasia with molecular biomarkers

scientific article published on 5 May 2006

EIN and WHO94.

scientific article published on January 2005

Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein

scientific article published on November 1991

Emerging concepts of apolipoprotein D with possible implications for breast cancer.

scientific article

Endometrial precancer diagnosis by histopathology, clonal analysis, and computerized morphometry

scientific article (publication date: March 2000)

Estrogen receptors in human breast cancer. II. Correlation between the histochemical method and biochemical assay.

scientific article published in January 1982

Evaluation of 5 different labeled polymer immunohistochemical detection systems

scientific article

Evaluation of MIB-1-positive cell clusters as a diagnostic marker for cervical intraepithelial neoplasia

scientific article published on 01 November 2002

Evaluation of a Diagnostic Encyclopedia Workstation for ovarian pathology

scientific article published on 01 October 1990

Evaluation of automated estimation of epithelial volume and its prognostic value in ovarian tumors

scientific article published in August 1989

Evaluation of the prognostic value of morphometric features and cellular DNA content in FIGO I ovarian cancer patients

scientific article published on 01 August 1987

Experience with a dynamic inexpensive video-conferencing system for frozen section telepathology.

scientific article published in January 2000

Exploring the possibility of DNA ploidy measurements in tissue sections using liver as a model

scientific article published on 01 February 1997

Expression of growth factors, growth factor receptors and apoptosis related proteins in invasive breast cancer: relation to apoptotic rate

scientific article published on 01 April 2001

Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops

scientific article published on 01 January 1998

Expression of growth factors, growth-inhibiting factors, and their receptors in invasive breast cancer. II: Correlations with proliferation and angiogenesis

scientific article published on 01 January 1998

Expression of multidrug resistance-associated markers, their relation to quantitative pathologic tumour characteristics and prognosis in advanced ovarian cancer.

scientific article

Expression of proliferation and apoptosis-related proteins in usual ductal hyperplasia of the breast.

scientific article

From SELDI-TOF MS to protein identification by on-chip elution.

scientific article published on 23 July 2011

Fully automated microvessel counting and hot spot selection by image processing of whole tumour sections in invasive breast cancer.

scientific article

Functional multidrug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-beta-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukemia.

scientific article

Further evaluation of quantitative nuclear image features for classification of lung carcinomas

scientific article published in June 1992

Further evaluation of reproducibility and prognostic value of histologic typing and grading in FIGO stage I ovarian cancer patients without systemic locoregional adjuvant treatment

scientific article published on 01 July 1995

Further evaluation of the prognostic value of morphometric and flow cytometric parameters in breast-cancer patients with long follow-up

scientific article published in January 1990

Further testing of morphometric grading in T(A,1) urothelial carcinomas of the urinary bladder and the additional value of p53 immunoquantitation

scientific article published on 01 April 2002

Further testing of the value of a measurement protocol for DNA ploidy studies using image cytometry. Comparison of results obtained from cytologic and paraffin section preparations

scientific article published on 01 October 1996

Gastric dysplasia: a stereological and morphometrical assessment

scientific article published on 01 June 1987

Genetic Alterations in Childhood Medulloblastoma Analyzed by Comparative Genomic Hybridization

scientific article published on 01 March 2002

Genetic analysis of 53 lymph node-negative breast carcinomas by CGH and relation to clinical, pathological, morphometric, and DNA cytometric prognostic factors

scientific article published on 01 December 1998

Genomics and proteomics in cancer

scientific article

Genomics and proteomics in neoplasia.

scientific article published on January 2007

Genomics and proteomics--the way forward

scientific article

Global expression changes of constitutive and hormonally regulated genes during endometrial neoplastic transformation

scientific article

Grading ovarian tumors. Evaluation of decision making by different pathologists.

scientific article published in December 1986

HPV tests at Stavanger University Hospital ⬇️

scientific article published on November 18, 2010

Helicobacter pylori-related and -non-related gastric cancers do not differ with respect to chromosomal aberrations

scientific article published on 01 November 2000

Heterogeneity and reproducibility of microvessel counts in breast cancer

scientific article published on 01 December 1995

Heterogeneity of mitotic activity in breast cancer.

scientific article published in November 1996

Highly sensitive, specific, and stable new fluorescent DNA stains for confocal laser microscopy and image processing of normal paraffin sections

scientific article published on November 1994

Hot spot microvessel density and the mitotic activity index are strong additional prognostic indicators in invasive breast cancer

scientific article published on 01 April 2000

Image processing for mitoses in sections of breast cancer: A feasibility study ⬇️

scientific article published on 01 May 1984

In Metastatic Non-small cell Lung Cancer Platinum-Based Treated Patients, Herbal Treatment Improves the Quality of Life. A Prospective Randomized Controlled Clinical Trial

scientific article published on 17 July 2017

In lymph node-negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumour diameter, and oestrogen receptor

scientific article

In patients younger than age 55 years with lymph node-negative breast cancer, proliferation by mitotic activity index is prognostically superior to adjuvant!

scientific article published on 28 December 2010

In search for the best qualitative microscopical or morphometrical predictor of oestrogen receptor in breast cancer

scientific article published on 01 March 1984

Increased apoptosis in gastric mucosa adjacent to intestinal metaplasia ⬇️

scientific article published on May 1, 2003

Increased expression of multidrug resistance related proteins Pgp, MRP1, and LRP/MVP occurs early in colorectal carcinogenesis

scientific article published on June 1999

Influence of boundary effects on minimum spanning tree features. A computer simulation

scientific article published on 01 June 1996

Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients ─ a randomized trial

scientific article published on 08 November 2019

Influence of section thickness, mean nuclear diameter and nuclear crowding on DNA ploidy in histologic sections of melanocytic skin lesions

scientific article published on 01 October 1999

Integrated decision support system/image archive for histological typing of breast cancer using a relation oriented inference system.

scientific article published on September 1994

Interaction of epithelial biomarkers, local immune response and condom use in cervical intraepithelial neoplasia 2-3 regression

scientific article

Interlaboratory reproducibility of semiautomated cell cycle analysis of flow cytometry DNA-histograms obtained from fresh material of 1,295 breast cancer cases.

scientific article published in June 1996

Interpathologist and intrapathologist disagreement in ovarian tumor grading and typing

scientific article published on 01 December 1986

Intra-patient variation between breast cancer axillary lymph node metastases using quantifiable features

scientific article published on 01 September 1992

Intratumor heterogeneity of k-ras and p53 mutations among human colorectal adenomas containing early cancer.

scientific article

Intratumor heterogeneity of morphometric and stereologic variables in primary ovarian tumors and their omental metastatic deposits

scientific article published on 01 June 1997

Is the improvement of prognosis of patients with metastatic pulmonary adenocarcinoma treated with TCM herbal medicine due to lag time to treatment bias?

scientific article published on 23 August 2011

Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model.

scientific article

Ki67 predicts progression in early CIN: validation of a multivariate progression-risk model.

scientific article

Kinetics and tissue distribution of the radiolabeled chimeric monoclonal antibody MOv18 IgG and F(ab')2 fragments in ovarian carcinoma patients

scientific article published on 01 November 1993

LOH at 1p31 (ARHI) and proliferation in lymph node-negative breast cancer.

scientific article

LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21.

scientific article published in May 2003

Limited prognostic value of cellular DNA content to classical and morphometrical parameters in invasive ductal breast cancer

scientific article

Local immune response in the microenvironment of CIN2-3 with and without spontaneous regression.

scientific article

Low p53 and retinoblastoma protein expression in cervical intraepithelial neoplasia grade 3 lesions is associated with coexistent adenocarcinoma in situ

scientific article published on 30 January 2008

Low- and high-risk CIN 1 and 2 lesions: prospective predictive value of grade, HPV, and Ki-67 immuno-quantitative variables

scientific article

Malignancy-associated changes in breast tissue detected by image cytometry.

scientific article

Malignant Brenner tumor. A histologic, morphometrical, immunohistochemical, and ultrastructural study

scientific article published on 01 August 1986

Measurement by confocal laser scanning microscopy of the volume of epidermal nuclei in thick skin sections.

scientific article published in April 1994

Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study

scientific article published on 04 December 2019

Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.

scientific article

Method for counting mitoses by image processing in Feulgen stained breast cancer sections

scientific article published on 01 January 1993

MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers

scientific article published on 05 May 2020

Microsatellite instability and DNA ploidy in colorectal cancer: potential implications for patients undergoing systematic surveillance after resection.

scientific article

Microsatellite instability in colorectal cancer

Minimum spanning tree analysis in advanced ovarian carcinoma. An investigation of sampling methods, reproducibility and correlation with histologic grade

scientific article published on 01 June 1997

Mitotic activity and bone marrow micrometastases have independent prognostic value in node positive breast cancer patients

scientific article published on 08 April 2011

Mitotic activity index and CD25+ lymphocytes predict risk of stage progression in non-muscle invasive bladder cancer

scientific article published on 02 June 2020

Molecular and biological factors in the pathogenesis of ovarian cancer

scientific article published on January 1993

Molecular biomarkers in endometrial hyperplasias predict cancer progression

scientific article published on 16 February 2011

Molecular identification of latent precancers in histologically normal endometrium.

scientific article published in June 2001

Monitoring serum CEA in women with primary breast tumours positive for oestrogen receptor and with spread to lymph nodes

scientific article

Morphometric and flow cytometric analysis of small cell undifferentiated carcinoma of the bladder

scientific article published on October 1989

Morphometric data to FIGO stage and histological type and grade for prognosis of ovarian tumours

scientific article

Morphometric definition and grading of gastric intestinal metaplasia

scientific article published on July 1990

Morphometric differences between urothelial cells in voided urine of patients with grade I and grade II bladder tumours ⬇️

scientific article published on June 1, 1981

Morphometric study of histological changes in sublabial salivary glands due to aging process

scientific article published on April 1986

Morphometrical analysis in endometrial hyperplasia: predictive of progression to cancer

scientific article published on 01 January 2006

Morphometry and breast cancer. II. Characterisation of breast cancer cells with high malignant potential in patients with spread to lymph nodes: preliminary results

scientific article published on June 1986

Morphometry and cytodiagnosis of breast lesions

scientific article published on 01 January 1982

Morphometry for prognosis prediction in breast cancer

scientific article published on 01 August 1981

Morphometry for the prognosis of acute lymphoblastic leukemia in childhood

scientific article published on 01 June 1987

Morphometry of breast cancer. I. Comparison of the primary tumours and the axillary lymph node metastases

scientific article published on 01 May 1986

Multivariate prognostic evaluation of the mitotic activity index and fibrotic focus in node-negative invasive breast cancers

scientific article published on 01 September 2005

Neoplastic transformation of endocervicosis into an extraovarian mucinous cystadenocarcinoma.

scientific article published on 15 January 2011

New chromosomal regions with high-level amplifications in squamous cell carcinomas of the larynx and pharynx, identified by comparative genomic hybridization

scientific article published on 01 June 2001

Non-random allelic losses at 3p, 11p and 13q during HPV-mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes.

scientific article published on May 1998

Nonradioactive RNA in situ hybridization detection of human papillomavirus 16-E7 transcripts in squamous cell carcinomas of the uterine cervix using confocal laser scan microscopy ⬇️

scientific article published on November 1, 1991

Nuclear cytometric changes in breast carcinogenesis

scientific article

Nuclear morphometry as an important prognostic factor in stage I renal cell carcinoma

scientific article published in December 1986

Nuclear size distinguishes low- from high-grade ovarian serous carcinoma and predicts outcome

scientific article published on 8 September 2005

Number of apoptotic cells as a prognostic marker in invasive breast cancer

scientific article published on January 2000

Origins of ... image analysis in clinical pathology

scientific article published on May 1997

Peripheral primitive neuroectodermal tumour and extra-osseous Ewing's sarcoma; a histological, immunohistochemical and DNA flow cytometric study ⬇️

scientific article published on 01 January 1995

Phosphohistone H3 expression has much stronger prognostic value than classical prognosticators in invasive lymph node-negative breast cancer patients less than 55 years of age.

scientific article

Potential clinical uses of laser scan microscopy

scientific article

Predicting the risk of metachronous colorectal cancer in patients with rectosigmoid adenoma using quantitative pathological features. A case-control study

scientific article published on January 1998

Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis

scientific article

Prediction of response to adjuvant chemotherapy in premenopausal lymph node positive breast cancer patients with morphometry, DNA flow cytometry and HER-2/neu oncoprotein expression. Preliminary results

scientific article published on April 1, 1992

Prediction of spontaneous regression of cervical intraepithelial neoplasia lesions grades 2 and 3 by proteomic analysis

scientific article

Prediction of the anti-inflammatory mechanisms of curcumin by module-based protein interaction network analysis

scientific article

Predictive testing of early CIN behaviour by molecular biomarkers.

scientific article

Production and Traffic of B Lymphocytes in the Extracortical Central Area of the Guinea Pig Thymus ⬇️

scientific article published on January 1, 1978

Progesterone and clomifene influence and stereologically estimated endometrial parameters

scientific article published on 01 January 1974

Prognostic Value of Microvessel Quantitation in Cisplatin Treated Figo 3 and 4 Ovarian Cancer Patients ⬇️

scientific article published on 01 February 1995

Prognostic comparison of proliferation markers and World Health Organization 1973/2004 grades in urothelial carcinomas of the urinary bladder

scientific article published on 26 March 2014

Prognostic comparison of the proliferation markers (mitotic activity index, phosphohistone H3, Ki67), steroid receptors, HER2, high molecular weight cytokeratins and classical prognostic factors in T₁₋₂N₀M₀ breast cancer

scientific article

Prognostic differences of World Health Organization-assessed mitotic activity index and mitotic impression by quick scanning in invasive ductal breast cancer patients younger than 55 years.

scientific article published on 4 March 2008

Prognostic factors in borderline and invasive ovarian tumors of the common epithelial type.

scientific article published on December 1987

Prognostic implications of different cell cycle analysis models of flow cytometric DNA histograms of 1,301 breast cancer patients: Results from the multicenter morphometric mammary carcinoma project (MMMCP) ⬇️

scientific article published on June 20, 1997

Prognostic indicators in WHO 2003 low-grade endometrial stromal sarcoma

scientific article published on 21 February 2013

Prognostic indicators in breast cancer--morphometric methods.

scientific article published in May 1982

Prognostic relevance of P-glycoprotein expression in breast cancer

scientific article published in September 1995

Prognostic relevance of androgen receptor detection in operable breast cancer

scientific article

Prognostic value and reproducibility of different microscopic characteristics in the WHO grading systems for pTa and pT1 urinary bladder urothelial carcinomas

scientific article published on 14 August 2019

Prognostic value and reproducibility of koilocytosis in cervical intraepithelial neoplasia

scientific article published on 01 July 2003

Prognostic value of DNA ploidy using flow cytometry in 1301 breast cancer patients: results of the prospective Multicenter Morphometric Mammary Carcinoma Project

scientific article published on 01 August 1997

Prognostic value of gene signatures and proliferation in lymph-node-negative breast cancer

scientific article

Prognostic value of morphometry and DNA flow-cytometry features of invasive breast cancers detected by population screening: comparison with control group of hospital patients

scientific article published on 01 May 1991

Prognostic value of morphometry in acute lymphoblastic leukemia of childhood

scientific article published on 01 April 1992

Prognostic value of morphometry in breast cancer

scientific article published on October 1991

Prognostic value of morphometry in patients with normal breast tissue or usual ductal hyperplasia of the breast

scientific article published on 01 September 2001

Prognostic value of nucleolar morphometric variables in cytological breast cancer specimens

scientific article published on February 1990

Prognostic value of proliferation in invasive breast cancer: a review

scientific article

Prognostic value of proliferative activity and nuclear morphometry for progression in TaT1 urothelial cell carcinomas of the urinary bladder

scientific article published on 01 December 2002

Prognostic value of proliferative activity in lymph node metastases of patients with breast cancer

scientific article published on May 1991

Prognostic value of quantitative pathologic features and DNA content in individual patients with stage I endometrial adenocarcinoma

scientific article published on April 1989

Prognostic value of the diagnostic criteria distinguishing endometrial stromal sarcoma, low grade from undifferentiated endometrial sarcoma, 2 entities within the invasive endometrial stromal neoplasia family

scientific article published on May 2013

Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation

scientific article published on December 1998

Proliferation accurately identifies the high-risk patients among small, low-grade, lymph node-negative invasive breast cancers

scientific article published on 27 November 2007

Proliferation is the strongest prognosticator in node-negative breast cancer: significance, error sources, alternatives and comparison with molecular prognostic markers

scientific article

Proliferation markers and DNA content analysis in urinary bladder TaT1 urothelial cell carcinomas: identification of subgroups with low and high stage progression risks

scientific article published on June 2003

Proliferation markers in tumours: interpretation and clinical value

scientific article

Proposal for therapeutic approach based on prognostic factors including morphometric and flow-cytometric features in stage iii-iv ovarian cancer ⬇️

scientific article published on May 1, 1988

Prospective Multicenter Validation Confirms the Prognostic Superiority of the Endometrial Carcinoma Prognostic Index in International Federation of Gynecology and Obstetrics Stage 1 and 2 Endometrial Carcinoma ⬇️

scientific article published on November 15, 2003

Prospective evaluation of prognostic value of morphometry in patients with primary breast cancer

scientific article

Prospective multicenter comparison of proliferation and other prognostic factors in lymph node negative lobular invasive breast cancer

scientific article published on 01 July 2009

Prospective multicenter evaluation of the morphometric D-score for prediction of the outcome of endometrial hyperplasias

scientific article published on 01 July 2001

Prospective multicenter validation of the independent prognostic value of the mitotic activity index in lymph node-negative breast cancer patients younger than 55 years.

scientific article published in September 2005

Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1alpha (HIF-1alpha)

scientific article published on 01 December 2003

Quality control methods for data entry in pathology using a computerized data management system based on an extended data dictionary ⬇️

scientific article published on February 1, 1992

Quantification by laser scan microscopy of intracellular doxorubicin distribution

scientific article

Quantification of epithelial area by image processing applied to endometrial carcinomas: a comparison with ovarian tumors

scientific article published on November 1989

Quantification of epithelial volume by image processing applied to ovarian tumors

scientific article published in July 1987

Quantification of proliferative activity in colorectal adenomas by mitotic counts: relationship to degree of dysplasia and histological type

scientific article published on July 1995

Quantitation of HER-2/neu oncoprotein overexpression in invasive breast cancer by image analysis: a study comparing fresh and paraffin-embedded material

scientific article published on 01 July 1991

Quantitation of borderline and malignant mucinous ovarian tumours

scientific article published on 01 July 1981

Quantitative assessment of gastric antrum atrophy shows restitution to normal histology after Helicobacter pylori eradication

scientific article published on 30 January 2004

Quantitative assessment of gastric corpus atrophy in subjects using omeprazole: a randomized follow-up study

scientific article published in October 2001

Quantitative cytologic and histologic techniques to assist in cancer evaluation

scientific article published on January 1, 1984

Quantitative determination of factors contributing to doxorubicin resistance in multidrug-resistant cells

scientific article published on December 1989

Quantitative histopathological analysis of CIN sections.

scientific article published in January 2006

Quantitative immunohistochemistry of estrogen and progesterone receptor positivity in ovarian tumors : a rapid and reliable stereological approach

scientific article published on January 2001

Quantitative immunohistochemistry using the CAS 200/486 image analysis system in invasive breast carcinoma: a reproducibility study.

scientific article published in April 1995

Quantitative immunohistologic and histomorphometric diagnostic criteria for Sjögren's syndrome

scientific article published on 01 November 1989

Quantitative methods in diagnostic pathology

scientific article published on January 1, 1990

Quantitative microscopical and confocal laser scanning microscopy for intermediate endpoint biomarkers in breast cancer: potential and reproducibility.

scientific article published on January 1993

Quantitative molecular parameters to identify low-risk and high-risk early CIN lesions: role of markers of proliferative activity and differentiation and Rb availability

scientific article published on April 2004

Quantitative morphology of the placenta II. The growth of the placenta and the problem of postmaturity ⬇️

scientific article published on February 1, 1978

Quantitative morphology of the placenta. III. The growth of the placenta and its relationship to birth weight.

scientific article

Quantitative nuclear image analysis: differentiation between normal, hyperplastic, and malignant appearing uterine glands in a paraffin section II. Computer assisted recognition by discriminant analysis ⬇️

scientific article published on January 1, 1977

Quantitative nuclear image analysis: differentiation between normal, hyperplastic, and malignant appearing uterine glands in a paraffin section III. The use of texture features for differentiation ⬇️

scientific article published on April 1, 1978

Quantitative nuclear image analysis: differentiation between normal, hyperplastic, and malignant appearing uterine glands in a paraffin section IV. The use of Markov chain texture features in discriminant analysis ⬇️

scientific article published on June 1, 1978

Quantitative pathologic analysis of first and second primary cancers in double tumors of the lung

scientific article published on 01 February 1989

Quantitative pathologic features as predictors of long-term survival in patients with advanced ovarian cancer treated with cisplatin

scientific article published on 01 May 1994

Quantitative prognostic features in FIGO I ovarian cancer patients without postoperative treatment

scientific article published on January 1998

Quantitative, microscopical, computer-aided diagnosis of endometrial hyperplasia or carcinoma in individual patients

scientific article published on 01 November 1981

Radioimmunotargeting in ovarian carcinoma patients with indium-111 labeled monoclonal antibody OV-TL 3 F(ab')2: pharmacokinetics, tissue distribution, and tumor imaging

scientific article published on 01 January 1992

Rapid and reliable assessment of volume percentage of epithelium in borderline and invasive ovarian tumors.

scientific article published in February 1998

Rapid quantitative assessment of gastric corpus atrophy in tissue sections

scientific article

Re: "the expressions of the Rb pathway in cervical intraepithelial neoplasia: predictive and prognostic significance" by Nam et al

scientific article published on 26 March 2007

Regional differences in breast cancer survival are correlated with differences in differentiation and rate of proliferation

scientific article published on September 1, 1992

Relationships between vascularization and proliferation in invasive breast cancer

scientific article published on 01 November 1999

Reliable DNA histogram interpretation. Number of nuclei requiring measurement with flow cytometry

scientific article published on 01 August 1997

Reporting by digital speech recognition ⬇️

scientific article published on August 1, 1995

Reproducibility and comparison of quantitative DNA histogram features obtained with a scanning microdensitometer and a flow cytometer in breast cancers

scientific article published on 01 October 1989

Reproducibility and prognostic value of WHO1973 and WHO2004 grading systems in TaT1 urothelial carcinoma of the urinary bladder

scientific article published on 07 January 2014

Reproducibility of counting immunoglobulin-containing cells in colonic mucosal biopsies

scientific article published on 01 April 1988

Reproducibility of flow cytometric assessment of follicular tumours of the thyroid

scientific article published on March 1989

Reproducibility of mitosis counting in 2,469 breast cancer specimens: results from the Multicenter Morphometric Mammary Carcinoma Project

scientific article published on June 1, 1992

Reproducibility of p53 and Ki-67 immunoquantitation in Barrett's esophagus

scientific article published on 01 June 1997

Reproducibility of semi-automated cell cycle analysis of flow cytometric DNA-histograms of fresh breast cancer material

scientific article published on 01 January 1995

Results of a study made during the European course on the application of quantitative pathology in clinical oncology

scientific article published on 01 March 1992

Retrospective study of prognostic importance of DNA flow cytometry of urinary bladder carcinoma

scientific article

Routine morphometrical analysis can improve reproducibility of dysplasia grade in Barrett's oesophagus surveillance biopsies

scientific article

Similarity in expression of cell cycle proteins between in situ and invasive ductal breast lesions of same differentiation grade

scientific article published on 01 July 2001

Squamous morules are functionally inert elements of premalignant endometrial neoplasia

scientific article published on 19 September 2008

Stages I to II WHO 2003-defined low-grade endometrial stromal sarcoma: how much primary therapy is needed and how little is enough?

scientific article published in March 2013

Standardization of counting micronuclei: definition of a protocol to measure genotoxic damage in human exfoliated cells.

scientific article published on October 1995

Standardized mitotic counts in breast cancer. Evaluation of the method.

scientific article published in September 1996

Stereological assessment of architectural changes in dysplastic epithelium of colorectal adenomas

scientific article published on April 1994

Success predictors of adjuvant chemotherapy in node-negative breast cancer patients under 55 years.

scientific article

Syntactic structure analysis in invasive breast cancer: analysis of reproducibility, biologic background, and prognostic value

scientific article published on 01 August 1992

Syntactic structure analysis of the arrangement of nuclei in dysplastic epithelium of colorectal adenomatous polyps

scientific article published on December 1, 1992

Syntactic structure analysis.

scientific article published on June 1995

Systematic random sampling for selective interactive nuclear morphometry in breast cancer sections. Refinement and multiobserver evaluation.

scientific article published in August 1993

Testing the value of a measurement protocol for DNA image cytometry and comparing different cytologic preparations

scientific article published on 01 December 1996

Text processing by digital voice recognition

scientific article published on 01 August 1996

The Multi-Center Morphometric Mammary Carcinoma Project (MMMCP) in The Netherlands: value of morphometrically assessed proliferation and differentiation

scientific article published on 01 January 1993

The Multicenter Morphometric Mammary Carcinoma Project (MMMCP). A nationwide prospective study on reproducibility and prognostic power of routine quantitative assessments in The Netherlands

scientific article published on 01 November 1989

The Multivariate Prognostic Index and nuclear DNA content are independent prognostic factors in primary breast cancer patients

scientific article published on 01 January 1989

The additional prognostic value of morphometric nuclear arrangement and DNA-ploidy to other morphometric and stereologic features in endometrial hyperplasias

scientific article

The application of morphometry in gastric cytological diagnosis ⬇️

scientific article published on 01 January 1981

The association between precancerous-columnar and squamous lesions of the cervix: a morphometric study.

scientific article published in November 1983

The effect of chemotherapy on the different components of advanced carcinosarcomas (malignant mixed mesodermal tumors) of the female genital tract

scientific article published on 01 January 1994

The effect of different DNA isolation methods on the outcome of high-risk HPV testing

scientific article published on 01 October 2007

The effect of sampling on quantitative nuclear image features in histologic sections of lung carcinomas.

scientific article published in October 1988

The framework of pathology: good laboratory practice by quantitative and molecular methods

scientific article

The impact of epithelial biomarkers, local immune response and human papillomavirus genotype in the regression of cervical intraepithelial neoplasia grades 2-3

scientific article published on 01 April 2011

The influence of fixation delay on mitotic activity and flow cytometric cell cycle variables

scientific article published on 01 January 1997

The influence of fixatives and other variations in tissue processing on nuclear morphometric features

scientific article published on 01 August 1989

The influence of variations in the measuring procedure on quantitative nuclear image features in histologic sections of lung tissue

scientific article published on 01 October 1988

The management of borderline epithelial tumors of the ovary

scientific article

The morphometric prognostic index is the strongest prognosticator in premenopausal lymph node-negative and lymph node-positive breast cancer patients

scientific article published in April 1991

The nuclei in cutaneous malignant melanoma, stage I, are smaller in survivors than in non-survivors

scientific article published in November 1989

The percentage of aneuploid cells is significantly correlated with survival in accurately staged patients with stage 1 resected squamous cell lung cancer and long-term follow up

scientific article published on 01 January 1989

The prognostic significance of selective nuclear morphometry in urinary bladder carcinoma

scientific article published on 01 April 1990

The prognostic value of MARCKS-like 1 in lymph node-negative breast cancer

scientific article published on 08 July 2012

The prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancer

scientific article

The prognostic value of molecular biomarkers in tissue removed by curettage from FIGO stage 1 and 2 endometrioid type endometrial cancer.

scientific article published on 30 October 2008

The prognostic value of morphometrical features and cellular DNA content in cis-platin treated late ovarian cancer patients

scientific article

The prognostic value of morphometry in ovarian epithelial tumors of borderline malignancy

scientific article published on 01 January 1985

The prognostic value of proliferation in lymph-node-negative breast cancer patients is age dependent

scientific article published on 15 November 2006

The prognostic value of the orphan nuclear receptor DAX-1 (NROB1) in node-negative breast cancer.

scientific article

The prognostic value of the proliferation marker phosphohistone H3 (PPH3) in luminal, basal-like and triple negative phenotype invasive lymph node-negative breast cancer.

scientific article published in January 2009

The prognostic variability of ovarian tumor grading by different pathologists

scientific article published on 01 June 1987

The relationship between syntactic structure analysis features, histological grade and high-risk HPV DNA in cervical intraepithelial neoplasia.

scientific article

The role of quantitative pathology in clinical decision making for Barrett's oesophagus.

scientific article published in January 2003

The significance of differences in prognostic value of quantitative pathologic features in FIGO stage III and IV serous adenocarcinoma of the ovary between a group of Danish patients and other groups

scientific article published in September 1995

The value of morphometry and DNA flow cytometry in addition to classic prognosticators in superficial urinary bladder carcinoma

scientific article

The value of morphometry to classic prognosticators in breast cancer.

scientific article published in July 1985

The value of p53 and Ki67 as markers for tumour progression in the Barrett's dysplasia-carcinoma sequence ⬇️

scientific article published on June 1, 1995

Three-dimensional confocal laser scanning DNA ploidy cytometry in thick histological sections

scientific article published on October 1996

Traditional Chinese medicine herbal treatment may have a relevant impact on the prognosis of patients with stage IV adenocarcinoma of the lung treated with platinum-based chemotherapy or combined targeted therapy and chemotherapy

scientific article published on 8 December 2010

Trends in breast cancer aggressiveness before the introduction of mass screening in southeastern Netherlands 1975-1989.

scientific article published in June 2002

Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.

scientific article

Tumor uptake of intravenously administered radiolabeled antibodies in ovarian carcinoma patients in relation to antigen expression and other tumor characteristics

scientific article published on 01 April 1995

Tumour heterogeneity of DNA cell cycle variables in breast cancer measured by flow cytometry

scientific article

Use of biomarkers in the evaluation of CIN grade and progression of early CIN.

scientific article

Use of computerized morphometric analyses of endometrial hyperplasias in the prediction of coexistent cancer

scientific article published on May 1996

Validating the prognostic value of proliferation measured by Phosphohistone H3 (PPH3) in invasive lymph node-negative breast cancer patients less than 71 years of age.

scientific article

Validation of expression patterns for nine miRNAs in 204 lymph-node negative breast cancers

scientific article

Validation study of MARCKSL1 as a prognostic factor in lymph node-negative breast cancer patients

Value of quantitative pathological variables as prognostic factors in advanced ovarian carcinoma

scientific article published on February 1996

Volume-weighted mean nuclear volume and nuclear area in advanced ovarian carcinoma. An investigation of sampling methods, sample size and reproducibility.

scientific article published in August 1995

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