List of works - Stephan A Müller

An optimised version of the secretome protein enrichment with click sugars (SPECS) method leads to enhanced coverage of the secretome.

scientific article published on 19 December 2016

CADASIL brain vessels show a HTRA1 loss-of-function profile

scientific article published on 03 May 2018

Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells

scientific article

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

scientific article published on 09 September 2019

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease

scientific article

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study

scientific article

Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue.

scientific article published on 29 July 2016

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

scientific article published on 08 June 2020

Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions

scientific article published on 19 October 2021

Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics.

scientific article published on 9 May 2013

Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor

scientific article published in Scientific Reports

Integration of conventional quantitative and phospho-proteomics reveals new elements in activated Jurkat T-cell receptor pathway maintenance

scientific article

Label-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects β-Site APP Cleaving Enzyme (BACE1) Protease Substrates In Vivo

scientific article

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

scientific article published on 24 February 2021

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

scientific article published on 07 January 2019

NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease

scientific article published on 01 April 2019

Optimization of parameters for coverage of low molecular weight proteins

scientific article published on 28 August 2010

Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis

scientific article published on 01 May 2020

Proteome data improves protein function prediction in the interactome of H. pylori.

scientific article published in February 2018

Proteomic Substrate Identification for Membrane Proteases in the Brain

scientific article

Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix

scientific article

RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data.

scientific article

Rational correction of pathogenic conformational defects in HTRA1

scientific article published in 2024

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease

scientific article published on 25 September 2018

Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.

scientific article published on 05 October 2016

Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins

scientific article published on 01 May 2019

Stable isotope labeling by amino acids in cell culture based proteomics reveals differences in protein abundances between spiral and coccoid forms of the gastric pathogen Helicobacter pylori

scientific article published on 12 May 2015

The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban

scientific article published on 07 February 2019

The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex

scientific article published on 28 February 2020

List of works by Stephan A Müller

An optimised version of the secretome protein enrichment with click sugars (SPECS) method leads to enhanced coverage of the secretome.

CADASIL brain vessels show a HTRA1 loss-of-function profile

Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study

Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue.

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions

Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics.

Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor

Integration of conventional quantitative and phospho-proteomics reveals new elements in activated Jurkat T-cell receptor pathway maintenance

Label-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects β-Site APP Cleaving Enzyme (BACE1) Protease Substrates In Vivo

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease

Optimization of parameters for coverage of low molecular weight proteins

Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis

Proteome data improves protein function prediction in the interactome of H. pylori.

Proteomic Substrate Identification for Membrane Proteases in the Brain

Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix

RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data.

Rational correction of pathogenic conformational defects in HTRA1

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease

Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.

Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins

Stable isotope labeling by amino acids in cell culture based proteomics reveals differences in protein abundances between spiral and coccoid forms of the gastric pathogen Helicobacter pylori

The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban

The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex