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List of works by Ingo Drexler

A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope

scientific article published on 29 August 2020

A novel cytosolic class I antigen-processing pathway for endoplasmic-reticulum-targeted proteins

scientific article

A phase I vaccination study with tyrosinase in patients with stage II melanoma using recombinant modified vaccinia virus Ankara (MVA-hTyr).

scientific article published on 31 December 2004

Active dissemination of cellular antigens by DCs facilitates CD8(+) T-cell priming in lymph nodes.

scientific article published on 5 September 2017

Antigen-dependent competition shapes the local repertoire of tissue-resident memory CD8+ T cells

scientific article

Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines

scientific article published on 14 May 2012

Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection

scientific article published on 04 July 2016

Broad and potent antiviral activity of the NAE inhibitor MLN4924.

scientific article published on February 2016

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

scientific article

Construction and isolation of recombinant MVA.

scientific article published on January 2004

Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccination

scientific article

Cross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines.

scientific article

Cutting edge: memory CD8 T cell compartment grows in size with immunological experience but nevertheless can lose function

scientific article published on 4 November 2009

Cutting edge: mucosal application of a lyophilized viral vector vaccine confers systemic and protective immunity toward intracellular pathogens

scientific article published in March 2009

Differential capacity of chaperone-rich lysates in cross-presenting human endogenous and exogenous melanoma differentiation antigens

scientific article

Gene Expression Driven by a Strong Viral Promoter in MVA Increases Vaccination Efficiency by Enhancing Antibody Responses and Unmasking CD8⁺ T Cell Epitopes

scientific article

HER-2/neu-mediated regulation of components of the MHC class I antigen-processing pathway.

scientific article published on January 2004

Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines.

scientific article

Immune Protection by a Cytomegalovirus Vaccine Vector Expressing a Single Low-Avidity Epitope

scientific article published on 2 August 2017

Immunization of mice with the nef gene from Human Immunodeficiency Virus type 1: study of immunological memory and long-term toxicology.

scientific article

Impact of the TAP-like transporter in antigen presentation and phagosome maturation

scientific article published on 23 June 2018

Impaired transporter associated with antigen processing (TAP) function attributable to a single amino acid alteration in the peptide TAP subunit TAP1.

scientific article published on January 2003

Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa.

scientific article

Infection of human dendritic cells with recombinant vaccinia virus MVA reveals general persistence of viral early transcription but distinct maturation-dependent cytopathogenicity

scientific article published on 3 April 2006

Interleukin-2-Inducible T-Cell Kinase Deficiency-New Patients, New Insight?

scientific article

Interplay between modified vaccinia virus Ankara and dendritic cells: phenotypic and functional maturation of bystander dendritic cells.

scientific article

Long-term immunity against actual poxviral HLA ligands as identified by differential stable isotope labeling

scientific article published on November 2008

Melanoma patients respond to a new HLA-A*01-presented antigenic ligand derived from a multi-epitope region of melanoma antigen TRP-2.

scientific article published in October 2005

Melanoma-reactive class I-restricted cytotoxic T cell clones are stimulated by dendritic cells loaded with synthetic peptides, but fail to respond to dendritic cells pulsed with melanoma-derived heat shock proteins in vitro

scientific article published on January 2004

Modified vaccinia virus Ankara as antigen delivery system: how can we best use its potential?

scientific article

Modified vaccinia virus Ankara delivers a robust surrogate marker for immune monitoring to sarcoma cells even if cells are being exposed to chemotherapy and heat treatment

scientific article published on January 2012

Modified vaccinia virus Ankara exerts potent immune modulatory activities in a murine model

scientific article

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway

scientific article

Modified vaccinia virus Ankara-infected dendritic cells present CD4+ T-cell epitopes by endogenous major histocompatibility complex class II presentation pathways

scientific article

Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol

scientific article published on 20 April 2018

Myxoma virus leukemia-associated protein is responsible for major histocompatibility complex class I and Fas-CD95 down-regulation and defines scrapins, a new group of surface cellular receptor abductor proteins

scientific article

Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production

scientific article published on 28 April 2014

Rapid In Vivo Conversion of Effector T Cells into Th2 Cells during Helminth Infection ⬇️

scientific article published on December 7, 2011

Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction

scientific article

Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines

scientific article published on 31 January 2012

Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells

scientific article published on July 2014

Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression

scientific article published on March 2017

Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia

scientific article published on 17 October 2016

The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation.

scientific article published on 6 April 2018

The poxviral scrapin MV-LAP requires a myxoma viral infection context to efficiently downregulate MHC-I molecules

scientific article published on 23 September 2005

The use of HLA-A*0201-transfected K562 as standard antigen-presenting cells for CD8+ T lymphocytes in IFN-γ ELISPOT assays ⬇️

scientific article published on January 1, 2002

Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens.

scientific article

Vaccinia Virus: From Crude Smallpox Vaccines to Elaborate Viral Vector Vaccine Design

scientific article published on 29 November 2021

α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets.

scientific article

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