List of works - Zenon Grabarek

A genetically encoded tool for manipulation of NADP+/NADPH in living cells

scientific article

Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly.

scientific article

Architecture of the mitochondrial calcium uniporter

scientific article published on 02 May 2016

Blocking the Ca2+-induced conformational transitions in calmodulin with disulfide bonds

scientific article

CLYBL is a polymorphic human enzyme with malate synthase and β-methylmalate synthase activity

scientific article

Calmodulin binds to caldesmon in an antiparallel manner

scientific article published on 01 December 1997

Characterization of zero-length cross-links between rabbit skeletal muscle troponin C and troponin I: evidence for direct interaction between the inhibitory region of troponin I and the NH2-terminal, regulatory domain of troponin C

scientific article published on 01 January 1990

Comparative studies on thermostability of calmodulin, skeletal muscle troponin C and their tryptic fragments

scientific article published on 01 March 1983

Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio

scientific article published on 7 April 2016

Conformational changes induced in troponin I by interaction with troponin T and actin/tropomyosin

scientific article

Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation

scientific article published on 13 October 2022

Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism

scientific article published on 12 February 2019

Degradation of TN-C component of troponin by trypsin

scientific article published on January 25, 1977

Differential effects of caldesmon on the intermediate conformational states of polymerizing actin

scientific article

Differential functional properties of calmodulin-dependent protein kinase IIgamma variants isolated from smooth muscle

scientific article

Digestion of troponin C with trypsin in the presence and absence of Ca2+. Identification of cleavage points

scientific article published on 01 December 1981

Distribution of troponin C and protein activator of 3′,5′-cyclic nucleotide phosphodiesterase in vertebrate tissues ⬇️

scientific article published on January 1, 1978

Dual Effect of ATP in the Activation Mechanism of Brain Ca2+/Calmodulin-Dependent Protein Kinase II by Ca2+/Calmodulin ⬇️

scientific article published on December 11, 2001

Extensive interactions between troponins C and I. Zero-length cross-linking of troponin I and acetylated troponin C

scientific article published on 01 August 1995

Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins.

scientific article

Fluorescence probe study of Ca2+-dependent interactions of calmodulin with calmodulin-binding peptides of the ryanodine receptor.

scientific article published in October 2004

High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter.

scientific article published on 14 June 2017

Inhibition of mutant troponin C activity by an intra-domain disulphide bond

scientific article published in Nature

Insights into modulation of calcium signaling by magnesium in calmodulin, troponin C and related EF-hand proteins ⬇️

scientific article published on January 22, 2011

John Gergely (1919-2013): a pillar in the muscle protein field.

scientific article

MARCKS is a major PKC-dependent regulator of calmodulin targeting in smooth muscle

scientific article published on 26 July 2005

MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca2+ and Mn2+

scientific article published on 06 August 2018

MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations

scientific article published on 11 November 2020

Modular structure of smooth muscle Myosin light chain kinase: hydrodynamic modeling and functional implications.

scientific article

Modulation of myosin filament activation by telokin in smooth muscle liberation of myosin kinase and phosphatase from supramolecular complexes.

scientific article published in January 2005

Molecular mechanism of troponin-C function

scientific article

Phosphorylation at Ser²⁶ in the ATP-binding site of Ca²⁺/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity.

scientific article published on 7 February 2013

Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins

scientific article

Properties of troponin C acetylated at lysine residues

scientific article published on 01 September 1995

Proton magnetic resonance studies on proteolytic fragments of troponin-C. Structural homology with the native molecule

scientific article published on 01 May 1980

Rat liver proteins binding and transferring phosphatidylserine

scientific article published on 01 August 1979

Similarity in Ca2+-induced changes between troponic-C and protein activator of 3':5'-cyclic nucleotide phosphodiesterase and their tryptic fragments

scientific article

Sodium-23 nuclear magnetic resonance as an indicator of sodium binding to troponin C and tryptic fragments, in relation to calcium content and attendant conformational changes

scientific article published on 01 April 1980

Stimulation of enzyme activities by fragments of calmodulin

scientific article published on 01 July 1981

Structural basis for diversity of the EF-hand calcium-binding proteins

scientific article (publication date: 9 June 2006)

Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin

scientific article

Structure of a trapped intermediate of calmodulin: calcium regulation of EF-hand proteins from a new perspective

scientific article published on 19 January 2005

Structure of the light chain-binding domain of myosin V

scientific article

Studies on structure and function of calmodulin.

scientific article

Terence Tao (1944-2020)

scientific article published on 19 May 2020

The Ca2+/Mg2+ sites of troponin C modulate crossbridge-mediated thin filament activation in cardiac myofibrils.

scientific article

The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.

scientific article published on 18 October 2017

The green tea polyphenol (-)-epigallocatechin-3-gallate inhibits magnesium binding to the C-domain of cardiac troponin C

scientific article published on 18 February 2013

The nature of the trifluoperazine binding sites on calmodulin and troponin-C

scientific article published on 01 December 1984

The role of Phe-92 in the Ca(2+)-induced conformational transition in the C-terminal domain of calmodulin

scientific article published on 01 May 1996

Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma

scientific article published on 01 August 2018

X-ray structures of magnesium and manganese complexes with the N-terminal domain of calmodulin: insights into the mechanism and specificity of metal ion binding to an EF-hand.

scientific article

Zero-length crosslinking procedure with the use of active esters

scientific article published on 01 February 1990

List of works by Zenon Grabarek

A genetically encoded tool for manipulation of NADP+/NADPH in living cells

Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly.

Architecture of the mitochondrial calcium uniporter

Blocking the Ca2+-induced conformational transitions in calmodulin with disulfide bonds

CLYBL is a polymorphic human enzyme with malate synthase and β-methylmalate synthase activity

Calmodulin binds to caldesmon in an antiparallel manner

Characterization of zero-length cross-links between rabbit skeletal muscle troponin C and troponin I: evidence for direct interaction between the inhibitory region of troponin I and the NH2-terminal, regulatory domain of troponin C

Comparative studies on thermostability of calmodulin, skeletal muscle troponin C and their tryptic fragments

Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio

Conformational changes induced in troponin I by interaction with troponin T and actin/tropomyosin

Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation

Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism

Degradation of TN-C component of troponin by trypsin

Differential effects of caldesmon on the intermediate conformational states of polymerizing actin

Differential functional properties of calmodulin-dependent protein kinase IIgamma variants isolated from smooth muscle

Digestion of troponin C with trypsin in the presence and absence of Ca2+. Identification of cleavage points

Distribution of troponin C and protein activator of 3′,5′-cyclic nucleotide phosphodiesterase in vertebrate tissues ⬇️

Dual Effect of ATP in the Activation Mechanism of Brain Ca2+/Calmodulin-Dependent Protein Kinase II by Ca2+/Calmodulin ⬇️

Extensive interactions between troponins C and I. Zero-length cross-linking of troponin I and acetylated troponin C

Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins.

Fluorescence probe study of Ca2+-dependent interactions of calmodulin with calmodulin-binding peptides of the ryanodine receptor.

High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter.

Inhibition of mutant troponin C activity by an intra-domain disulphide bond

Insights into modulation of calcium signaling by magnesium in calmodulin, troponin C and related EF-hand proteins ⬇️

John Gergely (1919-2013): a pillar in the muscle protein field.

MARCKS is a major PKC-dependent regulator of calmodulin targeting in smooth muscle

MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca2+ and Mn2+

MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations

Modular structure of smooth muscle Myosin light chain kinase: hydrodynamic modeling and functional implications.

Modulation of myosin filament activation by telokin in smooth muscle liberation of myosin kinase and phosphatase from supramolecular complexes.

Molecular mechanism of troponin-C function

Phosphorylation at Ser²⁶ in the ATP-binding site of Ca²⁺/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity.

Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins

Properties of troponin C acetylated at lysine residues

Proton magnetic resonance studies on proteolytic fragments of troponin-C. Structural homology with the native molecule

Rat liver proteins binding and transferring phosphatidylserine

Similarity in Ca2+-induced changes between troponic-C and protein activator of 3':5'-cyclic nucleotide phosphodiesterase and their tryptic fragments

Sodium-23 nuclear magnetic resonance as an indicator of sodium binding to troponin C and tryptic fragments, in relation to calcium content and attendant conformational changes

Stimulation of enzyme activities by fragments of calmodulin

Structural basis for diversity of the EF-hand calcium-binding proteins

Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin

Structure of a trapped intermediate of calmodulin: calcium regulation of EF-hand proteins from a new perspective

Structure of the light chain-binding domain of myosin V

Studies on structure and function of calmodulin.

Terence Tao (1944-2020)

The Ca2+/Mg2+ sites of troponin C modulate crossbridge-mediated thin filament activation in cardiac myofibrils.

The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.

The green tea polyphenol (-)-epigallocatechin-3-gallate inhibits magnesium binding to the C-domain of cardiac troponin C

The nature of the trifluoperazine binding sites on calmodulin and troponin-C

The role of Phe-92 in the Ca(2+)-induced conformational transition in the C-terminal domain of calmodulin

Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma

X-ray structures of magnesium and manganese complexes with the N-terminal domain of calmodulin: insights into the mechanism and specificity of metal ion binding to an EF-hand.

Zero-length crosslinking procedure with the use of active esters