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List of works by Alan R Healy

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

scientific article published on 16 March 2018

A Mechanistic Model for Colibactin-Induced Genotoxicity.

scientific article

Addendum: Synthesis and reactivity of precolibactin 886

scientific article published on 01 December 2019

An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin

scientific article published on 09 March 2019

ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance.

scientific article published on 7 November 2017

Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A.

scientific article published on 30 March 2016

Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin

scientific article published on 20 March 2015

Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis

scientific article

Model colibactins exhibit human cell genotoxicity in the absence of host bacteria

scientific article published on 20 November 2018

Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective.

scientific article published on 26 September 2017

Selective and Efficient Generation of ortho-Brominated para-Substituted Phenols in ACS-Grade Methanol

Stereochemical assignment of the protein-protein interaction inhibitor JBIR-22 by total synthesis.

scientific article published on 4 February 2015

Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway

scientific article published on 28 August 2017

Structure elucidation of colibactin and its DNA cross-links

scientific article

Synthesis and reactivity of precolibactin 886

scientific article published on 23 September 2019

Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes.

scientific article

Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels-Alder reaction.

scientific article

Total synthesis and biological evaluation of the tetramic acid based natural product harzianic acid and its stereoisomers

scientific article published on 28 January 2015

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