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List of works by Theo Klein

A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol

scientific article

Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure.

scientific article published on 14 October 2010

Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14.

scientific article published on 22 February 2016

Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses.

scientific article published on 22 September 2015

Activity-Dependent Photoaffinity Labeling of Metalloproteases

scientific article published in January 2017

An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient

scientific article published on 28 January 2019

Arginase inhibition prevents inflammation and remodeling in a guinea pig model of chronic obstructive pulmonary disease.

scientific article

C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.

scientific article published on 20 June 2018

DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics

scientific article published on 31 December 2020

Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation

scientific article published on 29 October 2018

Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction.

scientific article

Increased arginase activity contributes to airway remodelling in chronic allergic asthma ⬇️

scientific article published on February 10, 2011

MMP8 increases tongue carcinoma cell-cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5

scientific article published on 31 May 2021

Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death

scientific article published on 02 June 2020

N-Terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection.

scientific article published on 7 February 2018

Physiology and pathophysiology of matrix metalloproteases.

scientific article

Proteolytic Cleavage-Mechanisms, Function, and "Omic" Approaches for a Near-Ubiquitous Posttranslational Modification.

scientific article published on 21 December 2017

Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity

scientific article

Solid-Phase Synthesis of Succinylhydroxamate Peptides:  Functionalized Matrix Metalloproteinase Inhibitors

scientific article published in 2006

TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations

scientific article published on 04 October 2018

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