Search filters

List of works by Einar K. Rofstad

31P NMR spectroscopy studies of phospholipid metabolism in human melanoma xenograft lines differing in rate of tumour cell proliferation

scientific article published on 01 April 1995

31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia ⬇️

scientific article published on 01 October 1988

31P-nuclear magnetic resonance spectroscopy in vivo of four human melanoma xenograft lines: spin-lattice relaxation times

scientific article published on July 1994

31P-nuclear magnetic resonance spectroscopy in vivo of six human melanoma xenograft lines: tumour bioenergetic status and blood supply

scientific article published on December 1993

A novel application of dorsal window chambers: Repetitive imaging of tumor-associated lymphatics ⬇️

scientific article published on February 9, 2012

A novel method for mapping the heterogeneity in blood supply to normal and malignant tissues in the mouse dorsal window chamber

scientific article published on 6 August 2007

Activin A suppresses neuroblastoma xenograft tumor growth via antimitotic and antiangiogenic mechanisms

scientific article

Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts

scientific article

Antiangiogenic treatment with thrombospondin-1 enhances primary tumor radiation response and prevents growth of dormant pulmonary micrometastases after curative radiation therapy in human melanoma xenografts

scientific article published on 01 July 2003

Apoptosis, energy metabolism, and fraction of radiobiologically hypoxic cells: a study of human melanoma multicellular spheroids.

scientific article

Arrhenius analysis of the heat response in vivo and in vitro of human melanoma xenografts

scientific article published on 01 October 1986

Assessment of Tumor Radioresponsiveness and Metastatic Potential by Dynamic Contrast-Enhanced Magnetic Resonance Imaging ⬇️

scientific article published on September 1, 2011

Assessment of fraction of hypoxic cells in human tumor xenografts with necrotic regions by dynamic contrast-enhanced MRI.

scientific article

Assessment of fraction of radiobiologically hypoxic cells in human melanoma xenografts by dynamic contrast-enhanced MRI.

scientific article published in April 2006

Assessment of hypoxia and radiation response in intramuscular experimental tumors by dynamic contrast-enhanced magnetic resonance imaging ⬇️

scientific article published on December 24, 2011

Assessment of hypoxia in human cervical carcinoma xenografts by dynamic contrast-enhanced magnetic resonance imaging

scientific article published in March 2009

Assessment of the interstitial fluid pressure of tumors by dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights ⬇️

scientific article published on November 6, 2012

Assessment of tumor blood perfusion by high-resolution dynamic contrast-enhanced MRI: a preclinical study of human melanoma xenografts

scientific article

Assessment of tumor energy and oxygenation status by bioluminescence, nuclear magnetic resonance spectroscopy, and cryospectrophotometry

scientific article published on March 1990

Blood flow in six human melanoma xenograft lines with different growth characteristics ⬇️

scientific article published on February 1, 1992

Blood supply in melanoma xenografts is governed by the morphology of the supplying arteries

scientific article published on March 2009

Broad-Shouldered Survival Curves of a Human Melanoma Xenograft Implications for radiation therapy in the absence and presence of misonidazole ⬇️

scientific article published on January 1, 1981

Cancer stem cells (CSCs), cervical CSCs and targeted therapies

scientific article

Changes in oxygen tension during radiotherapy of head and neck tumours

scientific article published on 01 January 1999

Changes in temperatures and thermal doses with fraction number during hyperthermic treatment of locally advanced breast carcinoma ⬇️

scientific article published on 01 November 1991

Changes in tumor oxygen tension during radiotherapy of uterine cervical cancer: relationships to changes in vascular density, cell density, and frequency of mitosis and apoptosis

scientific article published on 01 March 2000

Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors

scientific article

Comparative imaging of structure and metabolites in tumours

scientific article published in July 1991

Correlation of high lactate levels in head and neck tumors with incidence of metastasis

scientific article published on February 1997

Correlation of high lactate levels in human cervical cancer with incidence of metastasis ⬇️

scientific article published on 01 November 1995

Critical soft tissues of the female pelvis: serial MR imaging before, during, and after radiation therapy

scientific article published on 01 May 1997

DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment

scientific article published on 3 November 2017

DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts

scientific article published on 11 November 2013

DW-MRI in assessment of the hypoxic fraction, interstitial fluid pressure, and metastatic propensity of melanoma xenografts

scientific article

Detection of different hypoxic cell subpopulations in human melanoma xenografts by pimonidazole immunohistochemistry

scientific article published in November 2008

Detection of necrosis in human tumour xenografts by proton magnetic resonance imaging

scientific article published on March 1995

Development of hypoxia in a preclinical model of tumor micrometastases

scientific article published in March 2010

Development of thermotolerance in a human melanoma xenograft

scientific article published on 01 February 1984

Differences in thermosensitization among cloned cell lines isolated from a single human melanoma xenograft

scientific article published on 01 May 1986

Differential responses to radiation and hyperthermia of cloned cell lines derived from a single human melanoma xenograft.

scientific article

Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer

scientific article published on 11 November 2017

Diffusion-weighted and dynamic contrast-enhanced MRI of pancreatic adenocarcinoma xenografts: associations with tumor differentiation and collagen content

scientific article published on 07 June 2016

Disease control of uterine cervical cancer: relationships to tumor oxygen tension, vascular density, cell density, and frequency of mitosis and apoptosis measured before treatment and during radiotherapy

scientific article published on 01 March 2000

Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts

scientific article published on 29 June 2017

Dynamic contrast-enhanced magnetic resonance imaging of human cervical carcinoma xenografts: pharmacokinetic analysis and correlation to tumor histomorphology.

scientific article published on 23 July 2010

Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of tumors: A preclinical study of cervical carcinoma and melanoma xenografts ⬇️

scientific article published on June 7, 2012

Dynamic contrast-enhanced magnetic resonance imaging of tumors: preclinical validation of parametric images

scientific article

Dynamic contrast‐enhanced‐MRI of tumor hypoxia ⬇️

scientific article published on June 9, 2011

Early effects of low dose bevacizumab treatment assessed by magnetic resonance imaging

scientific article published on 14 November 2015

Effect of Single Dose Irradiation on the Proliferation Kinetics in a Human Malignant Melanoma in Athymic Nude Mice ⬇️

scientific article published on January 1, 1980

Effect of cobalt-60 gamma rays and DTIC (5-(3,3 dimethyl-1-triazeno)-imidazole-r-carboxamide) on human malignant melanomas grown in athymic nude mice

scientific article published on May 1, 1977

Effect of melanin on phosphorus T1S in human melanoma xenografts studied by 31P MRS

scientific article published on 01 January 1995

Energy metabolism in human melanoma cells under hypoxic and acidic conditions in vitro

scientific article published on January 1997

Establishment and characterization of six human melanoma xenograft lines

scientific article published on October 1990

Establishment in monolayer culture and characterization of four human melanoma cell lines ⬇️

scientific article published on January 1, 1991

Female pelvic bone marrow: serial MR imaging before, during, and after radiation therapy

scientific article published on 01 February 1995

Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis

scientific article published on 14 March 2007

Fluctuations in pO2 in irradiated human melanoma xenografts

scientific article published on January 2006

Fluctuations in pO2 in poorly and well-oxygenated spontaneous canine tumors before and during fractionated radiation therapy

scientific article published on 27 October 2005

Fluctuations in tumor blood perfusion assessed by dynamic contrast-enhanced MRI.

scientific article published on September 2007

Fraction of radiobiologically hypoxic cells in human melanoma xenografts measured by using single-cell survival, tumour growth delay and local tumour control as end points ⬇️

scientific article published on October 1, 1998

Fractionated thermochemotherapy in vivo of a C3H mouse mammary carcinoma

scientific article published on July 1991

Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis

scientific article published on 29 July 2016

Growth rates or radiobiological hypoxia are not correlated with local metabolite content in human melanoma xenografts with similar vascular network

scientific article

Heat response of human melanoma multicellular spheroids: comparisons with single cells and xenografted tumors.

scientific article published in June 1985

Heat sensitivity and thermotolerance in cells from five human melanoma xenografts

scientific article published on 01 October 1984

Heterogeneity in heat sensitivity and development of thermotolerance of cloned cell lines derived from a single human melanoma xenograft

scientific article published in January 1985

Heterogeneity of glutathione content in human ovarian cancer

scientific article

Heterogeneous radiation and heat sensitivity in vitro of human melanoma xenograft lines established from different lesions in the same patient. Comparisons with the radiation and heat sensitivity of cells isolated from the donor patient's surgical s

scientific article published on June 1990

High Interstitial Fluid Pressure Is Associated with Tumor-Line Specific Vascular Abnormalities in Human Melanoma Xenografts ⬇️

scientific article published on June 29, 2012

High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers

scientific article published on 01 February 2000

Human cervical carcinoma xenograft models for studies of the physiological microenvironment of tumors

scientific article published on 13 February 2009

Hyperthermic radiosensitization of cells from a human melanoma xenograft

scientific article published on 01 July 1984

Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix

scientific article published on 26 October 2015

Hypoxia induces p53 accumulation in the S-phase and accumulation of hypophosphorylated retinoblastoma protein in all cell cycle phases of human melanoma cells

scientific article published on December 1998

Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor.

scientific article published in March 2002

Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: involvement of microvascular hot spots induced in hypoxic foci by interleukin 8.

scientific article published on January 2002

Hypoxia-induced angiogenesis and vascular endothelial growth factor secretion in human melanoma ⬇️

scientific article published on March 1, 1998

Hypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis

scientific article published on August 1999

Hypoxia-induced tetraploidisation of a diploid human melanoma cell line in vitro.

scientific article published on July 1996

Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis

scientific article published on August 2000

Identification of Metastasis-Associated Metabolic Profiles of Tumors by (1)H-HR-MAS-MRS

scientific article

Incidence of radiation-induced insufficiency fractures of the female pelvis: evaluation with MR imaging

scientific article published on 01 November 1996

Increased metastatic dissemination in human melanoma xenografts after subcurative radiation treatment: radiation-induced increase in fraction of hypoxic cells and hypoxia-induced up-regulation of urokinase-type plasminogen activator receptor

scientific article

Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation.

scientific article published on 20 April 2018

Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma

scientific article

Interstitial Fluid Pressure and Associated Lymph Node Metastasis Revealed in Tumors by Dynamic Contrast-Enhanced MRI ⬇️

scientific article published on October 1, 2012

Interstitial Fluid Pressure, Fraction of Necrotic Tumor Tissue, and Tumor Cell Density in Human Melanoma Xenografts ⬇️

scientific article published on 01 January 1998

Interstitial fluid pressure and capillary diameter distribution in human melanoma xenografts

scientific article

Interstitial fluid pressure in human melanoma xenografts. Relationship to fractional tumor water content, tumor size, and tumor volume-doubling time

scientific article published on January 1995

Interstitial fluid pressure, perfusion rate and oxygen tension in human melanoma xenografts.

scientific article published on July 1996

Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases

scientific article

Intra- and intertumor heterogeneity in blood perfusion of human cervical cancer before treatment and after radiotherapy

scientific article published on 01 June 2001

Intracranial Tumor Cell Migration and the Development of Multiple Brain Metastases in Malignant Melanoma

scientific article published on 17 May 2016

Intratumor heterogeneity in blood perfusion in orthotopic human melanoma xenografts assessed by dynamic contrast-enhanced magnetic resonance imaging

scientific article

Intratumor heterogeneity in perfusion in human melanoma xenografts measured by contrast-enhanced magnetic resonance imaging

scientific article published on 01 October 2000

Intratumour heterogeneity in the uptake of macromolecular therapeutic agents in human melanoma xenografts

scientific article published on January 2003

Limitations of dynamic contrast-enhanced MRI in monitoring radiation-induced changes in the fraction of radiobiologically hypoxic cells in human melanoma xenografts

scientific article

Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts

scientific article published on 26 May 2017

MRI of human tumor xenografts in vivo: proton relaxation times and extracellular tumor volume

scientific article published on 01 January 1995

Macromolecule uptake in human melanoma xenografts. relationships to blood supply, vascular density, microvessel permeability and extracellular volume fraction

scientific article published in July 2000

Magnetic resonance imaging identifies early effects of sunitinib treatment in human melanoma xenografts

scientific article

Magnetic resonance imaging of human melanoma xenografts in vivo: proton spin-lattice and spin-spin relaxation times versus fractional tumour water content and fraction of necrotic tumour tissue

scientific article published on March 1994

Magnetic resonance imaging of tumor necrosis ⬇️

scientific article published on October 18, 2010

Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging

scientific article published on 01 June 2000

Measurement of perfusion rate in human melanoma xenografts by contrast‐enhanced magnetic resonance imaging ⬇️

scientific article published on July 1, 1998

Measurement of proliferation activity in human melanoma xenografts by magnetic resonance imaging

scientific article

Measurement of the extracellular volume of human melanoma xenografts by contrast enhanced magnetic resonance imaging

scientific article published on 01 January 2000

Metastasis in Melanoma Xenografts Is Associated with Tumor Microvascular Density Rather than Extent of Hypoxia ⬇️

scientific article published on November 1, 2010

Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts

scientific article published on 10 October 2017

Microvascular permeability of human melanoma xenografts to macromolecules: relationships to tumor volumetric growth rate, tumor angiogenesis, and VEGF expression

scientific article published in March 2001

Microvascular permeability to macromolecules in human melanoma xenografts assessed by contrast-enhanced MRI—intertumor and intratumor heterogeneity ⬇️

scientific article published on June 1, 2001

Microvessel oxyhemoglobin saturation does not reflect tissue oxygen tension in human melanoma xenografts

scientific article published on 01 March 2001

Monitoring of tumor reoxygenation following irradiation by 31P magnetic resonance spectroscopy: an experimental study of human melanoma xenografts

scientific article published on 01 September 1999

N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth

scientific article published on 01 May 2002

Neutron capture therapy of intracerebral melanoma: enhanced survival and cure after blood-brain barrier opening to improve delivery of boronophenylalanine

scientific article published on March 2002

Non-invasive assessment of tumor oxygenation status by integrated 31P NMR spectroscopy and 1H NMR imaging

scientific article published on 01 January 1994

Noncritical soft tissues of the female pelvis: serial MR imaging before, during, and after radiation therapy

scientific article published on 01 May 1996

Oxygen Tension in Primary Tumours of the Uterine Cervix and Lymph Node Metastases of the Head and Neck ⬇️

scientific article published on 01 January 1997

Oxygen tension and vascular density in adenocarcinoma and squamous cell carcinoma of the uterine cervix

scientific article published on 01 January 1998

Oxygen tension and vascular density in human cervix carcinoma

scientific article

Oxygen tension in human tumours measured with polarographic needle electrodes and its relationship to vascular density, necrosis and hypoxia ⬇️

scientific article published on 01 August 1997

Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix

scientific article published on 29 January 2016

Photochemical internalization of bleomycin is superior to photodynamic therapy due to the therapeutic effect in the tumor periphery

scientific article

Polarographic measurement of pO2 in cervix carcinoma

scientific article published in February 1997

Preclinical evaluation of Gd-DTPA and gadomelitol as contrast agents in DCE-MRI of cervical carcinoma interstitial fluid pressure ⬇️

scientific article published on November 22, 2012

Prediction of treatment temperatures in clinical hyperthermia of locally advanced breast carcinoma: the use of contrast enhanced computed tomography

scientific article published on 01 June 1993

Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer

scientific article published on 28 February 2017

Primary and secondary cell death in human melanoma xenografts following hyperthermic treatment

scientific article published on 01 January 1986

Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression

scientific article published on 15 October 2016

Proton relaxation times and interstitial fluid pressure in human melanoma xenografts

scientific article published on January 1997

Pulmonary and lymph node metastasis is associated with primary tumor interstitial fluid pressure in human melanoma xenografts.

scientific article published in February 2002

Quantitative assessment of uptake and distribution of iron oxide particles (NC100150) in human melanoma xenografts by contrast-enhanced MRI.

scientific article published on April 2004

Radiation and heat sensitivity of cells from two slowly growing human melanoma xenografts

scientific article

Radiation response of multicellular spheroids initiated from five human melanoma xenograft lines. Relationship to the radioresponsiveness in vivo

scientific article published on 01 October 1986

Radiation sensitivity in vitro of cells isolated from human tumor surgical specimens

scientific article published on 01 January 1987

Radiation-induced changes in phosphorus T1 values in human melanoma xenografts studied by 31P-MRS.

scientific article published in January 1997

Radiocurability is associated with interstitial fluid pressure in human tumor xenografts

scientific article

Radiosensitization by misonidazole of a human malignant melanoma grown in athymic nude mice

scientific article published on 01 July 1980

Radiosensitizing effect of misonidazole in fractionated gamma-ray treatment of a human malignant melanoma grown in athymic nude mice ⬇️

scientific article published on May 1, 1979

Relationships between thermal dose and heat-induced tissue and vascular damage after thermoradiotherapy of locally advanced breast carcinoma

scientific article published on 01 May 1991

Response to heat treatment (42.5 degrees C) in vivo and in vitro of five human melanoma xenografts

scientific article published on 01 November 1984

Short-term pretreatment DCE-MRI in prediction of outcome in locally advanced cervical cancer

scientific article published on 18 May 2015

Spin-lattice relaxation time of inorganic phosphate in human tumor xenografts measured in vivo by 31P-magnetic resonance spectroscopy. Influence of oxygen tension

scientific article published on 01 January 1995

Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts ⬇️

scientific article published on September 4, 2012

Survival curves after X-ray and heat treatments for melanoma cells derived directly from surgical specimens of tumours in man.

scientific article published in August 1985

Temperature distribution in locally advanced breast carcinoma during hyperthermic treatment: Relationship to perfusion, vascular density, and histology ⬇️

scientific article published on 01 July 1991

Temporal heterogeneity in blood supply in human tumor xenografts

scientific article

Temporal heterogeneity in oxygen tension in human melanoma xenografts

scientific article published on July 2003

The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles

scientific article published on 02 February 2017

The Efficacy of CHK1 Inhibitors Is Not Altered by Hypoxia, but Is Enhanced after Reoxygenation ⬇️

scientific article published on May 1, 2013

The Microenvironment of Cervical Carcinoma Xenografts: Associations with Lymph Node Metastasis and Its Assessment by DCE-MRI.

scientific article published on October 2013

The constitutive level of vascular endothelial growth factor (VEGF) is more important than hypoxia-induced VEGF up-regulation in the angiogenesis of human melanoma xenografts

scientific article published in May 2000

The proliferation kinetics of NHIK 1922 cells in vitro and in solid tumours in athymic mice

scientific article published on 01 March 1980

The radiosensitizing effect of metronidazole and misonidazole (Ro–07–0582) on a human malignant melanoma grown in the athymic mutant nude mouse ⬇️

scientific article published on 01 May 1978

The relevance of tumour and surrounding normal tissue vascular density in clinical hyperthermia of locally advanced breast carcinoma

scientific article published in July 1991

The tumor bed effect: increased metastatic dissemination from hypoxia-induced up-regulation of metastasis-promoting gene products

scientific article published in March 2005

Thermal dose and secondary tumour cell death

scientific article published in September 1993

Thermochemotherapy in vivo of a C3H mouse mammary carcinoma: single fraction heat and drug treatment

scientific article published on 01 October 1988

Thermochemotherapy in vivo of a C3H mouse mammary carcinoma: thermotolerant tumours

scientific article

Thrombospondin-1 domain-containing peptide properdistatin improves vascular function in human melanoma xenografts

scientific article published on 17 February 2014

Thrombospondin-1 treatment prevents growth of dormant lung micrometastases after surgical resection and curative radiation therapy of the primary tumor in human melanoma xenografts

scientific article published on 01 February 2004

Transient perfusion in human melanoma xenografts

scientific article published on April 1995

Treatment failure following sequential thermoradiotherapy of locally advanced breast carcinoma occurs primarily in poorly vascularized tumors

scientific article published on 01 November 1995

Treatment outcome in advanced squamous cell carcinoma of the uterine cervix: relationships to pretreatment tumor oxygenation and vascularization

scientific article published on 01 February 2000

Tumor interstitial fluid pressure-a link between tumor hypoxia, microvascular density, and lymph node metastasis

scientific article

Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging

scientific article published on April 2008

Tumor-line specific causes of intertumor heterogeneity in blood supply in human melanoma xenografts ⬇️

scientific article published on November 10, 2012

Tumor-line specific pO(2) fluctuations in human melanoma xenografts

scientific article published on February 2004

Tumors exposed to acute cyclic hypoxia show increased vessel density and delayed blood supply

scientific article

Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination

scientific article

Tumour growth delay following single dose irradiation of human melanoma xenografts. Correlations with tumour growth parameters, vascular structure and cellular radiosensitivity

scientific article

Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix ⬇️

scientific article published on September 1, 1998

Tumour necrotisation in nude mice xenografts by the reversible protein synthesis inhibitor zilascorb(2H).

scientific article

Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts

scientific article published on 28 November 2017

Vascular abnormalities associated with acute hypoxia in human melanoma xenografts

scientific article published on 27 September 2012

Vascular changes in a human malignant melanoma xenograft following single-dose irradiation

scientific article published on 01 April 1984

Vascular density in human melanoma xenografts: relationship to angiogenesis, perfusion and necrosis ⬇️

scientific article published on January 30, 1998

Vascular structure of five human malignant melanomas grown in athymic nude mice

scientific article

Xenograft model systems for human melanoma

scientific article published on September 1996

pO2 Fluctuation Pattern and Cycling Hypoxia in Human Cervical Carcinoma and Melanoma Xenografts ⬇️

scientific article published on January 21, 2012

Paulina is supported by:

About Paulina

Help