List of works by Mark D. Okusa

A basic science view of acute kidney injury biomarkers.

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A(2A) adenosine receptor: a novel therapeutic target in renal disease

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A2A adenosine receptors on bone marrow-derived cells protect liver from ischemia-reperfusion injury

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Activated CD4+ T cells target mesangial antigens and initiate glomerulonephritis.

scientific article published on 19 October 2012

Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition

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Activation of adenosine 2A receptors preserves structure and function of podocytes

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Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury

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Acute Kidney Injury Prevention

scientific article published on 08 February 2016

Acute kidney injury associated with cardiac surgery

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Acute kidney injury due to 'coral reef syndrome'.

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Acute kidney injury in the cancer patient

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Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy

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Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF.

scientific article published on 5 April 2005

Association Analysis of the Reticulon 1 Gene in End-Stage Kidney Disease.

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Autocrine adenosine signaling promotes regulatory T cell-mediated renal protection

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Bioelectronic Approaches to Control Neuroimmune Interactions in Acute Kidney Injury

Biology of renal recovery: molecules, mechanisms, and pathways.

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Blocking the immune response in ischemic acute kidney injury: the role of adenosine 2A agonists

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C1 neurons mediate a stress-induced anti-inflammatory reflex in mice

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CAPing inflammation and acute kidney injury

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Cardiac surgery as a cause of acute kidney injury: pathogenesis and potential therapies

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Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes

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Coccidioidomycosis meningitis and syndrome of inappropriate antidiuretic hormone

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Combination Therapy With Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Antagonists in the Treatment of Patients With Type 2 Diabetes Mellitus

scientific article published on May 12, 2003

Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury

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Complement factor H gene associations with end-stage kidney disease in African Americans.

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Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy

scientific article published on 20 December 2017

Correction of renal hypertension after kidney transplantation from a donor with Gitelman syndrome

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Dangers within: DAMP responses to damage and cell death in kidney disease.

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Dendritic cell sphingosine 1-phosphate receptor-3 regulates Th1-Th2 polarity in kidney ischemia-reperfusion injury

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Dendritic cells in acute kidney injury: cues from the microenvironment

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Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury

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Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings

scientific article published on 22 March 2012

Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trials

scientific article published on 22 March 2012

Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology

scientific article published on 22 March 2012

Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury

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Driving change: kidney proximal tubule CSF-1 polarizes macrophages

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Dying cells and extracellular histones in AKI: beyond a NET effect?

scientific article published on 12 July 2012

Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI.

scientific article published on 30 October 2017

Effects of aging on renal function and regenerative capacity.

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Emerging therapeutic targets of sepsis-associated acute kidney injury

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Endothelial Dysfunction in Renal Interstitial Fibrosis.

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Endothelial Sphingosine 1‑Phosphate Receptor‑1 Mediates Protection and Recovery from Acute Kidney Injury

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Enhancing Nephrology Career Interest through the ASN Kidney TREKS Program

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Epithelial and Endothelial Pannexin1 Channels Mediate AKI

article published in 2018

Evaluation and initial management of acute kidney injury

scientific article published on 19 March 2008

Expanding role of T cells in acute kidney injury

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Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron Homeostasis

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IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury

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IL233, A Novel IL-2 and IL-33 Hybrid Cytokine, Ameliorates Renal injury

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Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

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Immune mechanisms and novel pharmacological therapies of acute kidney injury

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Impact of acute kidney injury on chronic kidney disease and its progression

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Inflammation in acute kidney injury.

scientific article published on 18 September 2008

Lack of Association of the APOL1 G3 Haplotype in African Americans with ESRD

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Lessons from Haiti on Disaster Relief

scientific article published on October 14, 2010

Macrophages, dendritic cells, and kidney ischemia-reperfusion injury

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Management of cirrhotic ascites: physiological basis of diuretic action

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Metabolic Syndrome Severity and Risk of CKD and Worsened GFR: The Jackson Heart Study

article published in 2018

Monocyte/macrophage chemokine receptor CCR2 mediates diabetic renal injury

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NKT cell activation mediates neutrophil IFN-gamma production and renal ischemia-reperfusion injury

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Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation

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Natural IgM and TLR Agonists Switch Murine Splenic Pan-B to "Regulatory" Cells That Suppress Ischemia-Induced Innate Inflammation via Regulating NKT-1 Cells

scientific article published on 23 August 2017

Natural IgM anti-leucocyte autoantibodies (IgM-ALA) regulate inflammation induced by innate and adaptive immune mechanisms.

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Natural IgM anti-leukocyte autoantibodies attenuate excess inflammation mediated by innate and adaptive immune mechanisms involving Th-17

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Natural killer T cell-derived IL-17 mediates lung ischemia-reperfusion injury

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Naturally occurring IgM anti-leukocyte autoantibodies (IgM-ALA) inhibit T cell activation and chemotaxis

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Naturally occurring IgM anti-leukocyte autoantibodies inhibit T-cell activation and chemotaxis

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Naturally occurring immunoglobulin M (nIgM) autoantibodies prevent autoimmune diabetes and mitigate inflammation after transplantation

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Nephron Physiology. Foreword.

scientific article published on 6 May 2009

Neuroimmune Control of Acute Kidney Injury and Inflammation

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Neuroimmune Interactions in Inflammation and Acute Kidney Injury

scientific article published on 9 August 2017

Nonpharmacological, Biomechanical Approaches to Control Inflammation in Acute Kidney Injury.

scientific article published on 9 June 2017

Optimal Role of the Nephrologist in the Intensive Care Unit

scientific article published on 3 December 2016

Outpatient Dialysis for Patients with AKI: A Policy Approach to Improving Care

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Pathogenesis of acute kidney injury: foundation for clinical practice

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Pharmacologic treatment of acute kidney injury: why drugs haven't worked and what is on the horizon

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Physiological biomarkers of acute kidney injury: a conceptual approach to improving outcomes

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Polymorphoneutrophilic infiltration in acute interstitial nephritis of Sjögren syndrome

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Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference

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Promoting Kidney Function Recovery in Patients with AKI Requiring RRT.

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Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction

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Proximal Tubule CD73 Is Critical in Renal Ischemia-Reperfusion Injury Protection

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Reading between the (guide)lines--the KDIGO practice guideline on acute kidney injury in the individual patient

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Recovery from acute kidney injury: predicting outcomes

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Regulatory T cells contribute to the protective effect of ischemic preconditioning in the kidney

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Regulatory T cells in AKI.

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Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury

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Renal Hemodynamics in AKI: In Search of New Treatment Targets

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Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages

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Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma

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Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells

scientific article published in September 2003

Role of interleukin 23 signaling in Clostridium difficile colitis

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Role of leukocytes in the pathogenesis of acute kidney injury

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Selective blockade of lysophosphatidic acid LPA3 receptors reduces murine renal ischemia-reperfusion injury

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Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney

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Sphingosine 1-Phosphate Receptor 3-Deficient Dendritic Cells Modulate Splenic Responses to Ischemia-Reperfusion Injury

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Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury.

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Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.

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Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists

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Takayasu arteritis presenting as a pulmonary-renal syndrome

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Targeting neural reflex circuits in immunity to treat kidney disease

scientific article published on 3 October 2017

Targeting of adenosine receptors in ischemia-reperfusion injury

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Targeting sphingosine 1 phosphate receptor type 1 receptors in acute kidney injury

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Technology Insight: biomarker development in acute kidney injury--what can we anticipate?

scientific article published on 29 January 2008

The Influence of Hemodialysis on T Regulatory Cells: A Meta-Analysis and Systematic Review

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The Nephrologist's Tumor: Basic Biology and Management of Renal Cell Carcinoma

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The changing pattern of acute kidney injury: from one to multiple organ failure

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The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia-reperfusion injury

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The inflammatory cascade in acute ischemic renal failure

The nexus of acute kidney injury, chronic kidney disease, and World Kidney Day 2009.

scientific article published on 18 February 2009

The renin-angiotensin system and its blockade in diabetic renal and cardiovascular disease

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The role of inflammation in the cardio-renal syndrome: a focus on cytokines and inflammatory mediators

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The role of tubuloglomerular feedback in the pathogenesis of acute kidney injury

scientific article published on 09 September 2011

The spleen: the forgotten organ in acute kidney injury of critical illness.

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Therapeutic Targets of Human AKI: Harmonizing Human and Animal AKI

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Ultrasound Contrast Agents in the Study of Kidney Function in Health and Disease

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Ultrasound Modulates the Splenic Neuroimmune Axis in Attenuating AKI.

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Ultrasound prevents renal ischemia-reperfusion injury by stimulating the splenic cholinergic anti-inflammatory pathway

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Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes.

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