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List of works by Martin H Brutsche

24h-gene variation effect of combined bevacizumab/erlotinib in advanced non-squamous non-small cell lung cancer using exon array blood profiling

scientific article published on 30 March 2017

A new dimension for beta2 -adrenoceptor gene polymorphisms

scientific article published on 01 July 2002

A randomised, controlled trial of bosentan in severe COPD.

scientific article published on 30 April 2008

Accelerometer- versus questionnaire-based assessment of physical activity and their changes over time in patients with COPD

scientific article

Accuracy of pleural puncture sites: a prospective comparison of clinical examination with ultrasound

scientific article published on 01 February 2003

Accuracy of the Hospital Anxiety and Depression Scale for identifying depression in chronic obstructive pulmonary disease patients

scientific article

Accuracy of ventilatory measurement employing ambulatory inductive plethysmography during tasks of everyday life

scientific article published on 20 February 2010

Acute respiratory health effects of urban air pollutants in adults with different patterns of underlying respiratory disease

scientific article published on 9 October 2012

Altered gene expression in myeloproliferative disorders correlates with activation of signaling by the V617F mutation of Jak2.

scientific article published on 4 August 2005

An individualized, adjustable maintenance regimen of budesonide/formoterol provides effective asthma symptom control at a lower overall dose than fixed dosing.

scientific article

Analysis of the EGFR mutation status in head and neck squamous cell carcinoma before treatment with Gefitinib.

scientific article

Analysis with respect to instrumental variables for the exploration of microarray data structures.

scientific article published on 29 September 2006

Apoptosis signals in atopy and asthma measured with cDNA arrays

Array-based diagnostic gene-expression score for atopy and asthma.

scientific article published in February 2002

Asthma and the regulated retrotransposon transcriptome

scientific article published on 01 September 2012

Asthma severity according to Global Initiative for Asthma and its determinants: an international study

scientific article

B-cell isotype control in atopy and asthma assessed with cDNA array technology

scientific article published on 01 April 2001

B-type natriuretic peptide and C-terminal-pro-endothelin-1 for the prediction of severely impaired peak oxygen consumption

scientific article

B-type natriuretic peptides for the evaluation of exercise intolerance

scientific article published in March 2009

Balloon dilatation using flexible bronchoscopy for the management of benign and malignant airway stenoses

scientific article published on 01 January 2004

Baseline predictors of adherence to positive airway pressure therapy for sleep apnea: a 10-year single-center observational cohort study.

scientific article published on 5 November 2013

Bevacizumab, Pemetrexed, and Cisplatin, or Bevacizumab and Erlotinib for Patients With Advanced Non-Small-Cell Lung Cancer Stratified by Epidermal Growth Factor Receptor Mutation: Phase II Trial SAKK19/09.

scientific article published on 5 March 2015

Biomarkers and peak oxygen uptake in patients with chronic lung disease

scientific article published on 17 July 2010

Bosentan for patients with steroid-resistant pulmonary sarcoidosis: a randomised controlled trial

scientific article published on 28 October 2018

Bronchial hyperresponsiveness and the development of asthma and COPD in asymptomatic individuals: SAPALDIA cohort study

scientific article

Bronchoalveolar lavage quality influences the T4/T8 ratio in sarcoidosis

scientific article published on 22 June 2007

CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T cell responses.

scientific article

Cardiopulmonary and gas-exchange responses during the six-minute walk test in patients with chronic obstructive pulmonary disease.

scientific article published on 9 September 2014

Challenge of exercise-induced asthma and exercise-induced bronchoconstriction

scientific article published on 01 February 2009

Characteristics of Asthma-related Nocturnal Cough: A Potential New Digital Biomarker

scientific article published on 03 December 2020

Characteristics of medically and surgically treated empyema patients: a retrospective cohort study.

scientific article

Circulating alpha1-antitrypsin in the general population: determinants and association with lung function

scientific article published on 25 April 2008

Circulating microRNA profiling in patients with advanced non-squamous NSCLC receiving bevacizumab/erlotinib followed by platinum-based chemotherapy at progression (SAKK 19/05).

scientific article published on 29 May 2014

Classification of Sleep Apnea Severity by Electrocardiogram Monitoring Using a Novel Wearable Device

scientific article published on 04 January 2020

Clinical Applicability of a Textile 1-Lead ECG Device for Overnight Monitoring

scientific article published on 28 May 2019

Clinical diagnosis of current asthma: predictive value of respiratory symptoms in the SAPALDIA study. Swiss Study on Air Pollution and Lung Diseases in Adults

scientific article published on 01 February 2001

Comorbidities and burden of COPD: a population based case-control study

scientific article

Comparison of next generation sequencing, SNaPshot assay and real-time polymerase chain reaction for lung adenocarcinoma EGFR mutation assessment

scientific article

Comparison of pharmacokinetics and systemic effects of inhaled fluticasone propionate in patients with asthma and healthy volunteers: a randomised crossover study

scientific article published in The Lancet

Complementary and alternative medicine for bronchial asthma: is there new evidence?

scientific article

Complementary and alternative medicine in asthma--safety, effectiveness and costs

scientific article published on 01 June 2002

Comprehensive biomarker profiling in patients with obstructive sleep apnea.

scientific article published on 16 September 2014

Copeptin response to clinical maximal exercise tests

scientific article published on 28 January 2010

Cough and dyspnea during exertion 14 days after nicotine use

scientific article

Cough suppression during flexible bronchoscopy using combined sedation with midazolam and hydrocodone: a randomised, double blind, placebo controlled trial

scientific article published on September 2004

Current allergic asthma and rhinitis: diagnostic efficiency of three commonly used atopic markers (IgE, skin prick tests, and Phadiatop). Results from 8329 randomized adults from the SAPALDIA Study. Swiss Study on Air Pollution and Lung Diseases in

scientific article published on 01 June 1998

Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA).

scientific article

Decreased PM10 exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect

scientific article

Design and validation of an interpretative strategy for cardiopulmonary exercise tests

scientific article published in November 2007

Determinants of annual change in physical activity in COPD.

scientific article published on 30 March 2017

Determinants of change in airway reactivity over 11 years in the SAPALDIA population study

scientific article published on 7 June 2010

Diagnosis and management of chronic obstructive pulmonary disease: the Swiss guidelines. Official guidelines of the Swiss Respiratory Society

scientific article published on 11 February 2013

Diagnosis, Prevention and Treatment of Stable COPD and Acute Exacerbations of COPD: The Swiss Recommendations 2018

scientific article published on 23 August 2018

Diagnostic diversity - an indicator of institutional and regional healthcare quality

scientific article published on 15 December 2018

Diarrhea, erythema nodosum, arthralgia

scientific article published in August 1993

Differences in heart rate variability associated with long-term exposure to NO2

scientific article published on 20 June 2008

Digitalizing multidisciplinary pulmonary rehabilitation in COPD with a smartphone application: an international observational pilot study

Does higher monocyte count predict increased alcohol consumption?

scientific article published on 01 January 1995

Does hypoxemia have an impact on the cardiac release and circulating concentrations of natriuretic peptides in humans in vivo?

scientific article published on 22 November 2012

EGFR exon-level biomarkers of the response to bevacizumab/erlotinib in non-small cell lung cancer

scientific article

Early detection of lung cancer: a statement from an expert panel of the Swiss university hospitals on lung cancer screening

scientific article published on 16 January 2014

Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease

scientific article

Effect of a clinical procalcitonin algorithm to guide antibiotic therapy in patients with lower respiratory tract infections outside study conditions: a post-study survey.

scientific article published on 13 March 2009

Effect of physical activity on heart rate variability in normal weight, overweight and obese subjects: results from the SAPALDIA study

scientific article published on 03 July 2008

Effect of telemetric monitoring in the first 30 days of continuous positive airway pressure adaptation for obstructive sleep apnoea syndrome - a controlled pilot study.

scientific article published on 6 August 2015

Effectiveness of a procalcitonin algorithm to guide antibiotic therapy in respiratory tract infections outside of study conditions: a post-study survey

scientific article published on 29 December 2009

Efficacy of infliximab in extrapulmonary sarcoidosis: results from a randomised trial

scientific article published on 06 February 2008

End-stage cystic fibrosis: improved diabetes control 2 years after successful isolated pancreatic cell and double-lung transplantation.

scientific article published on December 1997

Endobronchial ultrasound-guided transbronchial needle aspiration of an intravascular sarcoma metastasis.

scientific article published on 24 September 2013

Epidermal growth factor receptor mutation in a patient with squamous cell carcinoma of the lung: who should be tested?

scientific article published on 14 May 2013

Erlotinib has comparable clinical efficacy to chemotherapy in pretreated patients with advanced non-small cell lung cancer (NSCLC): A propensity-adjusted, outcomes research-based study.

scientific article published on 28 July 2016

Erratum to: NIV by an interdisciplinary respiratory care team in severe respiratory failure in the emergency department limited to day time hours

scientific article

Exercise capacity and extent of resection as predictors of surgical risk in lung cancer

scientific article published on 01 May 2000

Exercise-induced bronchospasm (EIB) in relation to seasonal and perennial specific IgE in young adults

scientific article published on 01 November 1995

Exploring the transcription factor activity in high-throughput gene expression data using RLQ analysis

scientific article

Feasibility of mobile cardiopulmonary exercise testing

scientific article published on 01 January 2006

Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991-2003: methods and characterization of participants.

scientific article published in January 2005

Functional genomics and gene microarrays--the use in research and clinical medicine

scientific article

Functional genomics and prognosis in sarcoidosis--the critical role of antigen presentation

scientific article published in March 2004

Functional genomics in sarcoidosis--reduced or increased apoptosis?

scientific article published on August 2001

Gene Expression Signatures Predictive of Bevacizumab/Erlotinib Therapeutic Benefit in Advanced Nonsquamous Non-Small Cell Lung Cancer Patients (SAKK 19/05 trial).

scientific article published on 28 April 2015

Gene profiling of clinical routine biopsies and prediction of survival in non-small cell lung cancer

scientific article published on 15 October 2009

Glutathione S-transferase genotype increases risk of progression from bronchial hyperresponsiveness to asthma in adults

scientific article

HLA-DR2 predicts susceptibility and disease chronicity in Irish sarcoidosis patients.

scientific article published in October 2004

HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction

scientific article published in March 2010

Handheld single photon emission computed tomography (handheld SPECT) navigated video-assisted thoracoscopic surgery of computer tomography-guided radioactively marked pulmonary lesions.

scientific article published on 20 May 2016

Hemodynamic effects of endobronchial application of ornipressin versus terlipressin.

scientific article

High-throughput alternative splicing detection using dually constrained correspondence analysis (DCCA).

scientific article published on 16 October 2015

Idiopathic Pulmonary Fibrosis in Switzerland: Diagnosis and Treatment

scientific article published on 25 March 2017

Impact of comorbidities on physical activity in COPD.

scientific article published on 6 January 2015

Impact of intracoronary ultrasound guidance on long-term outcome of percutaneous coronary interventions in diabetics--insights from the randomized SIPS trial

scientific article published on 01 June 2002

Impact of laughter on air trapping in severe chronic obstructive lung disease.

scientific article published on January 2008

Improvements in PM10Exposure and Reduced Rates of Respiratory Symptoms in a Cohort of Swiss Adults (SAPALDIA)

article

In-Hospital Disease Burden of Sarcoidosis in Switzerland from 2002 to 2012.

scientific article

Indacaterol and glycopyrronium versus indacaterol on body plethysmography measurements in COPD-a randomised controlled study.

scientific article published on 11 January 2017

Induction chemotherapy followed by parenchyma-sparing surgery in medically inoperable NSCLC-results of a feasibility study.

scientific article

Infliximab therapy in patients with chronic sarcoidosis and pulmonary involvement

scientific article

Interstitial lung disease in an intravenous drug user.

scientific article published in January 2003

Interstitial pneumonitis after treatment with pemetrexed: a rare event?

scientific article published on 23 February 2012

Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia

scientific article published on 3 April 2008

Long-term follow-up and survival after Ultraflex stent insertion in the management of complex malignant airway stenoses

scientific article

Long-term treatment with infliximab in patients with sarcoidosis

scientific article published on 29 July 2011

Longitudinal change of COPD assessment test (CAT) in a telehealthcare cohort is associated with exacerbation risk

scientific article published on 24 October 2017

Longitudinal change of prebronchodilator spirometric obstruction and health outcomes: results from the SAPALDIA cohort.

scientific article

Lymphoproliferative responses in cord blood and at one year: no evidence for the effect of in utero exposure to dust mite allergens

article

Management of parapneumonic effusion and empyema: medical thoracoscopy and surgical approach.

scientific article

Manchester Asthma and Allergy Study: Low-allergen environment can be achieved and maintained during pregnancy and in early life

scientific article published on 01 February 2000

Midregional pro-A-type natriuretic peptide for the evaluation of exercise intolerance

scientific article published on 19 January 2010

Midregional pro-adrenomedullin and copeptin: exercise kinetics and association with the cardiopulmonary exercise response in comparison to B-type natriuretic peptide

scientific article published on 05 January 2014

Modeling the oxygen uptake kinetics during exercise testing of patients with chronic obstructive pulmonary diseases using nonlinear mixed models.

scientific article

Multimodel inference applied to oxygen recovery kinetics after 6-min walk tests in patients with chronic obstructive pulmonary disease

scientific article

NIV by an interdisciplinary respiratory care team in severe respiratory failure in the emergency department limited to day time hours.

scientific article published on 8 October 2016

Natriuretic peptides for the prediction of severely impaired peak VO2 in patients with lung disease.

scientific article published on 16 April 2009

No impact of exacerbation frequency and severity on the physical activity decline in COPD: a long-term observation

scientific article published on 15 February 2019

Nocturnal Cough and Sleep Quality to Assess Asthma Control and Predict Attacks

scientific article published on 14 December 2020

Notice of retraction

scientific article published on 01 December 2003

Occupational exposure to dusts, gases, and fumes and incidence of chronic obstructive pulmonary disease in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults

scientific article published on 6 April 2012

Operator experience and long term outcome after percutaneous coronary intervention.

scientific article published in August 2003

Optimized between-group classification: a new jackknife-based gene selection procedure for genome-wide expression data

scientific article

Outcome of treated advanced non-small cell lung cancer with and without central airway obstruction.

scientific article

Oxygen Uptake Recovery Kinetics after the 6-Minute Walk Test in Patients with Chronic Obstructive Pulmonary Disease

scientific article published on 9 November 2016

Oxygen kinetics during 6-minute walk tests in patients with cardiovascular and pulmonary disease.

scientific article

Passive smoking exposure in adults and chronic respiratory symptoms (SAPALDIA Study). Swiss Study on Air Pollution and Lung Diseases in Adults, SAPALDIA Team

scientific article published on 01 November 1994

Past, present and future of gene expression-tailored therapy for lung cancer

scientific article published on 01 May 2006

Physical activity and the frequency of acute exacerbations in patients with chronic obstructive pulmonary disease.

scientific article published on 13 December 2014

Physical activity declines in COPD while exercise capacity remains stable: A longitudinal study over 5 years

scientific article published on 18 June 2018

Pleural Kaposi's sarcoma: a potentially overlooked manifestation

scientific article published on 01 January 2000

Prediction of treatment-response to inhaled corticosteroids by mannitol-challenge test in COPD. A proof of concept

scientific article published on 21 December 2004

Prevalence of airflow obstruction in smokers and never-smokers in Switzerland.

scientific article published on 22 April 2010

Prevalence of coeliac disease in patients with sarcoidosis.

scientific article

Prevalence of nocturnal cough in asthma and its potential as a marker for asthma control (MAC) in combination with sleep quality: protocol of a smartphone-based, multicentre, longitudinal observational study with two stages

scientific article published on 07 January 2019

Prevalence of sarcoidosis in Switzerland is associated with environmental factors

scientific article published on 6 November 2009

Previous cytomegalovirus infection and restenosis after aggressive angioplasty with provisional stenting.

scientific article published in August 2003

Progressive pulmonary sarcoidosis--a fibroproliferative process potentially triggered by EGR-1 and IL-6.

scientific article published on March 2006

Progressive static pulmonary hyperinflation in survivors of severe bronchopulmonary dysplasia by mid-adulthood

scientific article published on 25 August 2011

Pulmonary (99m)Tc-DTPA aerosol clearance and survival in usual interstitial pneumonia (UIP)

scientific article

Pulmonary function in idiopathic pulmonary fibrosis and referral for lung transplantation

scientific article published in July 2001

Quantifying patient centered outcomes associated with the use of bilateral endobronchial coil treatment in patients with severe emphysema.

scientific article published on 6 April 2018

Receiving the diagnosis of lung cancer: patient recall of information and satisfaction with physician communication

scientific article published on January 2008

Reduced exposure to PM10 and attenuated age-related decline in lung function.

scientific article published in December 2007

Sarcoidosis is a multisystem disorder with variable prognosis--information for treating physicians.

scientific article

Sedative drug requirements during flexible bronchoscopy

scientific article published in November 2005

Selexipag for the Treatment of Pulmonary Arterial Hypertension

scientific article published in December 2015

Significant progress in palliative treatment of non-small cell lung cancer in the past decade.

scientific article

Significant reduction of AECOPD hospitalisations after implementation of a public smoking ban in Graubünden, Switzerland

scientific article published on 05 February 2014

Six-minute walk test enhanced by mobile telemetric cardiopulmonary monitoring

scientific article published on 10 August 2010

Small RNA profiling reveals deregulated phosphatase and tensin homolog (PTEN)/phosphoinositide 3-kinase (PI3K)/Akt pathway in bronchial smooth muscle cells from asthmatic patients.

scientific article published on 3 July 2015

Sputum DNA sequencing in cystic fibrosis: non-invasive access to the lung microbiome and to pathogen details.

scientific article published on 10 February 2017

Stability of gene contributions and identification of outliers in multivariate analysis of microarray data

scientific article

Successful treatment of steroid-refractory neurosarcoidosis with infliximab

scientific article published on 01 June 2004

Systemic Th1- and Th2-gene signals in atopy and asthma

scientific article published in March 2004

Telehealthcare for Chronic Obstructive Pulmonary Disease in Switzerland Is Feasible and Appreciated by Patients

scientific article published on 24 August 2016

The Effect of Incidental Consolidation on Management and Outcomes in COPD Exacerbations: Data from the European COPD Audit

scientific article

The outcome of community-acquired pneumonia in patients with chronic lung disease: a case-control study.

scientific article published on 3 September 2014

Therapeutic bronchoscopy for malignant airway stenoses: choice of modality and survival.

scientific article

Therapeutic bronchoscopy interventions before surgical resection of lung cancer.

scientific article published on May 2006

Tiotropium Respimat inhaler and the risk of death in COPD.

scientific article

Tracheal granuloma pyogenicum with erlotinib treatment for lung cancer

scientific article published on 01 November 2011

Traffic-related air pollution correlates with adult-onset asthma among never-smokers

scholarly article by N Kunzli et al published 8 April 2009 in Thorax

Transcutaneous versus blood carbon dioxide monitoring during acute noninvasive ventilation in the emergency department - a retrospective analysis

scientific article published on 26 October 2016

Treatment of complicated spontaneous pneumothorax by simple talc pleurodesis under thoracoscopy and local anaesthesia

scientific article published on April 1997

Treatment of sonographically stratified multiloculated thoracic empyema by medical thoracoscopy.

scientific article published in November 2005

Use of studded Polyflex stents in patients with neoplastic obstructions of the central airways.

scientific article published in January 2004

Variable radiomorphologic data of high altitude pulmonary edema. Features from 60 patients.

scientific article

VeriStrat® has a prognostic value for patients with advanced non-small cell lung cancer treated with erlotinib and bevacizumab in the first line: pooled analysis of SAKK19/05 and NTR528.

scientific article published in November 2012

[A rare cause of dyspnea on exertion. A 76-year-old retired woman]

scientific article published on 01 August 2006

[ARDS after Incidental Aspiration of Petroleum in an Adult]

scientific article published on 28 January 2015

[Campaign against smoking and the general practitioner. Evaluation of a simple method allowing immediate measurement of compliance with smoking cessation in the physicians office]

scientific article published on 01 November 1993

[Cardiopulmonary exercise testing (CPET) – indication and clinical impact]

scientific article published on 01 May 2015

[Combination of asthma and COPD: more frequent as considered to be?]

scientific article published on 01 June 2006

[Ovarian hyperstimulation syndrome (OHSS): a radiologically little known complication of the hormonal treatment of infertility]

scientific article published on 01 March 2001

[Sarcoidosis--a multisystem disorder with variable prognosis]

scientific article published on 01 January 2016

[The role of chronic or transient hypoxia on the retinal nerve fiber layers].

scientific article published on 22 April 2015

[Thoracic surgery for non-small cell lung cancer. Cost-benefit of its management in specialized intermediate care]

scientific article published on 01 January 1996

[Value of thoracoscopy and talc pleurodesis in diagnosis and palliative treatment of malignant pleural mesothelioma]

scientific article published on 01 March 1998

[Young man with exercise-induced dyspnea]

scientific article published on 01 October 2001

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