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List of works by Jan J De Waele

A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

scientific article published on 01 November 2017

A Simulation Study Reveals Lack of Pharmacokinetic/Pharmacodynamic Target Attainment in De-escalated Antibiotic Therapy in Critically Ill Patients

scientific article published on 26 May 2015

A Step-up Approach, or Open Necrosectomy for Necrotizing Pancreatitis ⬇️

scientific article published on September 23, 2010

A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care Unit

scientific article published on 23 December 2015

A microbiologist consultant should attend daily ICU rounds

scientific article published on 14 November 2019

A survey of beta-lactam antibiotics and vancomycin dosing strategies in intensive care units and general wards in Belgian hospitals ⬇️

scientific article published on December 28, 2012

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

scientific article published on 16 January 2014

Antimicrobial de-escalation as part of antimicrobial stewardship in intensive care: no simple answers to simple questions-a viewpoint of experts

scientific article published on 05 February 2020

Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill P

scientific article published on 28 November 2019

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

scientific article published on 09 June 2020

Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. A position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance.

scientific article published on 29 December 2017

Antimicrobial stewardship in ICUs during the COVID-19 pandemic: back to the 90s?

scientific article published on 17 October 2020

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA).

scientific article

Assays for therapeutic drug monitoring of β-lactam antibiotics: A structured review

scientific article published on 29 July 2015

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic

scientific article

Designing a Pharmacokinetic Machine Learning Model for Optimizing Beta-Lactam Antimicrobial Dosing in Critically Ill Patients

scientific article published on 09 September 2024

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study

scientific article

Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome: a systematic review and meta-analysis

scientific article published on 25 July 2018

Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients.

scientific article published in May 2015

How I search for a sepsis source

scientific article published on 29 November 2019

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patien

scientific article

Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference

scientific article

Management of necrotizing skin and soft tissue infections ⬇️

scientific article published on July 1, 2012

Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?

scientific article

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

scientific article

Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients

scientific article published on 25 June 2013

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures

scientific article published on 10 June 2014

Population pharmacokinetics of piperacillin continuous infusion in critically ill patients

scientific article

Prolonged Versus Intermittent Infusion of β-Lactam Antibiotics: A Systematic Review and Meta-Regression of Bacterial Killing in Preclinical Infection Models

scientific article published on 25 July 2020

Randomised clinical trial of moxifloxacin versus ertapenem in complicated intra-abdominal infections: results of the PROMISE study ⬇️

scientific article published on November 13, 2012

Rational Use of Antimicrobials in Patients with Severe Acute Pancreatitis ⬇️

scientific article published on April 19, 2011

Reply to Rhodes et al.

scientific article

Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients

scientific article published on 23 July 2014

Subtleties in practical application of prolonged infusion of β-lactam antibiotics

scientific article published on 16 February 2015

The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs

scientific article published on 13 July 2015

The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship-results from an international cross-sectional survey.

scientific article published on August 2017

What about confidence intervals? A word of caution when interpreting PTA simulations.

scientific article published on 4 May 2016

What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance

scientific article published on 06 April 2012

Why We May Need Higher Doses of Beta-Lactam Antibiotics: Introducing the ‘Maximum Tolerable Dose’

scientific article published in 2022

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