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List of works by Andrew J Schork

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

scientific article published on 22 March 2021

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

scientific article published on 28 January 2019

A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness

scientific article published on 09 March 2020

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

scientific article published on 11 November 2019

A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia

A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function

article

Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms

scientific article published on 8 April 2015

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

scientific article

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

scientific article published on 29 December 2015

Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry

scientific article published on 12 September 2017

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

scientific article published on 18 April 2016

Association between Mental Disorders and Subsequent Medical Conditions

scientific article published on 01 April 2020

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition

scientific article published on 30 October 2019

Author Correction: A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function

scientific article published on 14 February 2020

Autonomic and hemodynamic origins of pre-hypertension: central role of heredity

scientific article

Beyond heritability: Improving discoverability in imaging genetics

scientific article published on 7 March 2018

Common genetic variants influence human subcortical brain structures

scientific article

Conservation of Distinct Genetically-Mediated Human Cortical Pattern

scientific article

Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms

scientific article published on 15 May 2015

Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

scientific article published on 01 March 2020

Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

scientific article published on 5 November 2015

Covariate-modulated local false discovery rate for genome-wide association studies

scientific article published on 7 April 2014

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

scientific article

Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

scientific article

Enrichment of genetic markers of recent human evolution in educational and cognitive traits

scientific article published in Scientific Reports

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

scientific article published on 16 February 2016

Exploring Comorbidity Within Mental Disorders Among a Danish National Population

scientific article published on 01 March 2019

Genes and environment: novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure

scientific article

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic Markers of Human Evolution Are Enriched in Schizophrenia

scientific article

Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci

scientific article published on 22 December 2015

Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus

scientific article published on 15 July 2021

Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases

scientific article

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

scientific article

Genetic correlations of polygenic disease traits: from theory to practice

scientific article published on 01 October 2019

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study

scientific article published on 10 June 2020

Genetic implication of a novel thiamine transporter in human hypertension

scientific article

Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors

scientific article

Genetic predictors of educational attainment and intelligence test performance predict voter turnout

scientific article published on 09 November 2020

Genetic risks and clinical rewards

scientific article published on 01 September 2018

Genetic variation at the delta-sarcoglycan (SGCD) locus elevates heritable sympathetic nerve activity in human twin pairs

scientific article published on 19 July 2013

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study

article

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases

scientific article published on 05 June 2017

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders

scientific article published on 05 December 2016

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

scientific article published on 16 October 2020

Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study

scientific article published on 7 May 2015

Human Disease Variation in the Light of Population Genomics

scientific article published on 01 March 2019

Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected]

scientific article published on 16 October 2013

Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment

scientific article published on 23 June 2016

Identification of novel loci affecting circulating chromogranins and related peptides.

scientific article

Identification of shared genetic variants between schizophrenia and lung cancer.

scientific article published on 12 January 2018

Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors

scientific article

Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes

scientific article published on 06 January 2014

Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

scientific article

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

scientific article

Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome

scientific article

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditions

Large-scale genomics unveil polygenic architecture of human cortical surface area

scientific article published on 20 July 2015

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS.

scientific article published on 25 January 2016

Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure

scientific article

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

scientific article

MicroRNAs enrichment in GWAS of complex human phenotypes

scientific article

Modeling prior information of common genetic variants improves gene discovery for neuroticism

scientific article published on 30 August 2017

Modeling the 3D geometry of the cortical surface with genetic ancestry

scientific article published on 9 July 2015

Neuropeptide Y (NPY): genetic variation in the human promoter alters glucocorticoid signaling, yielding increased NPY secretion and stress responses

scientific article published on 26 September 2012

New statistical approaches exploit the polygenic architecture of schizophrenia--implications for the underlying neurobiology

scientific article

Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment

scientific article published on 26 November 2017

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

O4.6. GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS.

scientific article

Pleiotropic Analysis of Lung Cancer and Blood Triglycerides

scientific article

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

scientific article

Probing the Association between Early Evolutionary Markers and Schizophrenia

scientific article

Restricted ethnic diversity in human embryonic stem cell lines

scientific article published on January 2010

Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap

scientific article published on 07 January 2019

Shared common variants in prostate cancer and blood lipids

scientific article

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.

scientific article

Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

scientific article published in Nature Communications

Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis.

scientific article published on 16 February 2017

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

scientific article published on 02 September 2019

Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes.

scientific article published on 8 June 2018

Williams syndrome-specific neuroanatomical profile and its associations with behavioral features

scientific article

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