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List of works by Marie-France Langelier

A third zinc-binding domain of human poly(ADP-ribose) polymerase-1 coordinates DNA-dependent enzyme activation

scientific article

Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY

scientific article

Focus on RNA polymerase II

scientific article published on 15 February 2002

Functional dissection of the catalytic mechanism of mammalian RNA polymerase II.

scientific article

Inhibitors of Multisubunit RNA Polymerases as Tools to Study Transcriptional Mechanisms in Prokaryotes and Eukaryotes

article

Interaction networks of the molecular machines that decode, replicate, and maintain the integrity of the human genome

scientific article published on 22 June 2004

NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains

scientific article published on 27 February 2018

PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis ⬇️

scientific article published on January 16, 2013

PARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1.

scientific article

Photo-cross-linking of a purified preinitiation complex reveals central roles for the RNA polymerase II mobile clamp and TFIIE in initiation mechanisms.

scientific article published on February 2004

Purification of DNA Damage-Dependent PARPs from E. coli for Structural and Biochemical Analysis

scientific article published in January 2017

Purification of human PARP-1 and PARP-1 domains from Escherichia coli for structural and biochemical analysis

scientific article published on January 1, 2011

Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs

scientific article published on 19 February 2015

RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits

scientific article

Structural Basis for DNA Damage–Dependent Poly(ADP-ribosyl)ation by Human PARP-1 ⬇️

scientific article published on May 11, 2012

Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.

scientific article published on 24 November 2015

Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling

scientific article published on 28 February 2013

Structural perspective on mutations affecting the function of multisubunit RNA polymerases

scientific article

Tail and Kinase Modules Differently Regulate Core Mediator Recruitment and Function In Vivo

scientific article

Tankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt Signaling

scientific article

Tankyrase-1 Ankyrin Repeats Form an Adaptable Binding Platform for Targets of ADP-Ribose Modification

scientific article

Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer

scientific article

The RPB2 Flap Loop of Human RNA Polymerase II Is Dispensable for Transcription Initiation and Elongation ⬇️

scientific article published on June 13, 2011

The Zn3 domain of human poly(ADP-ribose) polymerase-1 (PARP-1) functions in both DNA-dependent poly(ADP-ribose) synthesis activity and chromatin compaction

scientific article

The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II.

scientific article

The nucleosomal surface is the main target of histone ADP-ribosylation in response to DNA damage

scientific article

Unfolding of core nucleosomes by PARP-1 revealed by spFRET microscopy

scientific article published on 5 January 2017

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