List of works - Roland K.O Sigel

A QM/MM refinement of an experimental DNA structure with metal-mediated base pairs

scientific article

A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories

scientific article published in 2022

Acid-base and metal-ion binding properties of the RNA dinucleotide uridylyl-(5'-->3')-[5']uridylate (pUpU3-).

scientific article

BOBA FRET: bootstrap-based analysis of single-molecule FRET data

scientific article

Binding interaction of [Re(H2O)3(CO)3]+ with the DNA fragment d(CpGpG).

scientific article

Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junction

scientific article

Cation-induced kinetic heterogeneity of the intron-exon recognition in single group II introns

scientific article

Characterization of metal ion-nucleic acid interactions in solution.

scientific article published on January 2012

Characterization of the full-length btuB riboswitch from Klebsiella pneumoniae

scientific article published on 21 December 2015

Comparison of the acid-base properties of ribose and 2'-deoxyribose nucleotides.

scientific article published in January 2008

Discrimination in metal-ion binding to RNA dinucleotides with a non-bridging oxygen or sulfur in the phosphate diester link.

scientific article

Distance-dependent duplex DNA destabilization proximal to G-quadruplex/i-motif sequences.

scientific article published on 14 June 2013

Divalent metal ions promote the formation of the 5'-splice site recognition complex in a self-splicing group II intron

scientific article published on 27 August 2008

Divalent metal ions tune the self-splicing reaction of the yeast mitochondrial group II intron Sc.ai5gamma.

scientific article

Diversity of cobalamin riboswitches in the corrinoid-producing organohalide respirer Desulfitobacterium hafniense

scientific article published on 13 September 2013

Explicit analytic equations for multimolecular thermal melting curves.

scientific article published on 9 April 2015

Heavy metal mutagenicity: insights from bioinorganic model chemistry.

scientific article

Helicase-mediated changes in RNA structure at the single-molecule level.

scientific article published on January 2013

Hydrogen bonding patterns of 7,9-dimethylguanine and its transplatinum(II) complexes

Kinetic subpopulations detected by single-molecule spectroscopy: fundamental property of functional nucleic acids or experimental artefact?

scientific article

MINAS--a database of Metal Ions in Nucleic AcidS

scientific article

Metal ion binding sites in a group II intron core

scientific article published on 01 December 2000

Metal ion-N7 coordination in a ribozyme branch domain by NMR.

scientific article published on 28 January 2010

Metal ion-RNA interactions studied via multinuclear NMR

scientific article published on 01 January 2012

Metal ions and sugar puckering balance single-molecule kinetic heterogeneity in RNA and DNA tertiary contacts

scientific article published on 08 January 2020

Metal-modified nucleobase sextet: joining four linear metal fragments (trans-a2PtII) and six model nucleobases to an exceedingly stable entity.

scientific article published in May 2001

Mg(2+)-induced conformational changes in the btuB riboswitch from E. coli

scientific article

Mimicking the in vivo Environment--The Effect of Crowding on RNA and Biomacromolecular Folding and Activity

scientific article published on 01 January 2015

Monitoring global structural changes and specific metal-ion-binding sites in RNA by in-line probing and Tb(III) cleavage.

scientific article published in January 2014

NMR structure of the 5' splice site in the group IIB intron Sc.ai5 --conformational requirements for exon-intron recognition

scientific article

Protonation-Dependent Base Flipping at Neutral pH in the Catalytic Triad of a Self-Splicing Bacterial Group II Intron

scientific article published on 26 June 2015

PtII Binding to N1 of Cytosine: Strengthening the Watson-Crick Pair with Guanine and yet Confining Its pH Existence Range

Puf6 primes 60S pre-ribosome nuclear export at low temperature

scientific article published on 04 August 2021

Pyrazine as a building block for molecular architectures with PtII.

scientific article

Reliable State Identification and State Transition Detection in Fluorescence Intensity-Based Single-Molecule Förster Resonance Energy-Transfer Data

scientific article published on 05 June 2018

Secondary structure confirmation and localization of Mg2+ ions in the mammalian CPEB3 ribozyme.

scientific article published on 10 March 2016

Shaping RNA structures with metal ions and metal ion complexes.

scientific article published on January 2010

Simulations of camera-based single-molecule fluorescence experiments

scientific article published on 13 April 2018

Single molecule FRET characterization of large ribozyme folding.

scientific article

Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain

scientific article

Solution structure of a DNA double helix with consecutive metal-mediated base pairs

scientific article

Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif

scientific article

Solution structure of domain 6 from a self-splicing group II intron ribozyme: a Mg(2+) binding site is located close to the stacked branch adenosine

scientific article

Strategy for Internal Labeling of Large RNAs with Minimal Perturbation by Using Fluorescent PNA.

scientific article published on 18 May 2015

Structure and Conformational Dynamics of the Domain 5 RNA Hairpin of a Bacterial Group II Intron Revealed by Solution Nuclear Magnetic Resonance and Molecular Dynamics Simulations

article

Studying metal ion binding properties of a three-way junction RNA by heteronuclear NMR.

scientific article published on 15 February 2016

Synthesis and acid-base properties of an imidazole-containing nucleotide analog, 1-(2'-deoxy-β-D-ribofuranosyl)imidazole 5'-monophosphate (dImMP(2-)).

scientific article

Synthesis, physico-chemical properties and biological analysis of newly obtained copper(II) complexes with pyrazole derivatives

scientific article published on 10 March 2014

Synthesis, structure, physico-chemical and biological properties of metal(II) complexes with 5-amino-8-methyl-4H-benzopyran-4-one

scientific article published in January 2014

The AdoCbl-riboswitch interaction investigated by in-line probing and surface plasmon resonance spectroscopy (SPR).

scientific article published in January 2014

The Role of Mg(II) in DNA Cleavage Site Recognition in Group II Intron Ribozymes

scientific article

The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations

scientific article published on 27 June 2016

The change of corrin-amides to carboxylates leads to altered structures of the B12-responding btuBriboswitch ⬇️

scientific article published on September 10, 2010

The corrin moiety of coenzyme B12 is the determinant for switching the btuB riboswitch of E. coli.

scientific article published in June 2008

The structural stabilization of the κ three-way junction by Mg(II) represents the first step in the folding of a group II intron ⬇️

scientific article published on December 28, 2012

Unusually high-affinity Mg(2+) binding at the AU-rich sequence within the antiterminator hairpin of a Mg(2+) riboswitch.

scientific article published on September 2012

Using in vitro transcription to construct scaffolds for one-dimensional arrays of mercuric ions.

scientific article

List of works by Roland K.O Sigel

A QM/MM refinement of an experimental DNA structure with metal-mediated base pairs

A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories

Acid-base and metal-ion binding properties of the RNA dinucleotide uridylyl-(5'-->3')-[5']uridylate (pUpU3-).

BOBA FRET: bootstrap-based analysis of single-molecule FRET data

Binding interaction of [Re(H2O)3(CO)3]+ with the DNA fragment d(CpGpG).

Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junction

Cation-induced kinetic heterogeneity of the intron-exon recognition in single group II introns

Characterization of metal ion-nucleic acid interactions in solution.

Characterization of the full-length btuB riboswitch from Klebsiella pneumoniae

Comparison of the acid-base properties of ribose and 2'-deoxyribose nucleotides.

Discrimination in metal-ion binding to RNA dinucleotides with a non-bridging oxygen or sulfur in the phosphate diester link.

Distance-dependent duplex DNA destabilization proximal to G-quadruplex/i-motif sequences.

Divalent metal ions promote the formation of the 5'-splice site recognition complex in a self-splicing group II intron

Divalent metal ions tune the self-splicing reaction of the yeast mitochondrial group II intron Sc.ai5gamma.

Diversity of cobalamin riboswitches in the corrinoid-producing organohalide respirer Desulfitobacterium hafniense

Explicit analytic equations for multimolecular thermal melting curves.

Heavy metal mutagenicity: insights from bioinorganic model chemistry.

Helicase-mediated changes in RNA structure at the single-molecule level.

Hydrogen bonding patterns of 7,9-dimethylguanine and its transplatinum(II) complexes

Kinetic subpopulations detected by single-molecule spectroscopy: fundamental property of functional nucleic acids or experimental artefact?

MINAS--a database of Metal Ions in Nucleic AcidS

Metal ion binding sites in a group II intron core

Metal ion-N7 coordination in a ribozyme branch domain by NMR.

Metal ion-RNA interactions studied via multinuclear NMR

Metal ions and sugar puckering balance single-molecule kinetic heterogeneity in RNA and DNA tertiary contacts

Metal-modified nucleobase sextet: joining four linear metal fragments (trans-a2PtII) and six model nucleobases to an exceedingly stable entity.

Mg(2+)-induced conformational changes in the btuB riboswitch from E. coli

Mimicking the in vivo Environment--The Effect of Crowding on RNA and Biomacromolecular Folding and Activity

Monitoring global structural changes and specific metal-ion-binding sites in RNA by in-line probing and Tb(III) cleavage.

NMR structure of the 5' splice site in the group IIB intron Sc.ai5 --conformational requirements for exon-intron recognition

Protonation-Dependent Base Flipping at Neutral pH in the Catalytic Triad of a Self-Splicing Bacterial Group II Intron

PtII Binding to N1 of Cytosine: Strengthening the Watson-Crick Pair with Guanine and yet Confining Its pH Existence Range

Puf6 primes 60S pre-ribosome nuclear export at low temperature

Pyrazine as a building block for molecular architectures with PtII.

Reliable State Identification and State Transition Detection in Fluorescence Intensity-Based Single-Molecule Förster Resonance Energy-Transfer Data

Secondary structure confirmation and localization of Mg2+ ions in the mammalian CPEB3 ribozyme.

Shaping RNA structures with metal ions and metal ion complexes.

Simulations of camera-based single-molecule fluorescence experiments

Single molecule FRET characterization of large ribozyme folding.

Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain

Solution structure of a DNA double helix with consecutive metal-mediated base pairs

Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif

Solution structure of domain 6 from a self-splicing group II intron ribozyme: a Mg(2+) binding site is located close to the stacked branch adenosine

Strategy for Internal Labeling of Large RNAs with Minimal Perturbation by Using Fluorescent PNA.

Structure and Conformational Dynamics of the Domain 5 RNA Hairpin of a Bacterial Group II Intron Revealed by Solution Nuclear Magnetic Resonance and Molecular Dynamics Simulations

Studying metal ion binding properties of a three-way junction RNA by heteronuclear NMR.

Synthesis and acid-base properties of an imidazole-containing nucleotide analog, 1-(2'-deoxy-β-D-ribofuranosyl)imidazole 5'-monophosphate (dImMP(2-)).

Synthesis, physico-chemical properties and biological analysis of newly obtained copper(II) complexes with pyrazole derivatives

Synthesis, structure, physico-chemical and biological properties of metal(II) complexes with 5-amino-8-methyl-4H-benzopyran-4-one

The AdoCbl-riboswitch interaction investigated by in-line probing and surface plasmon resonance spectroscopy (SPR).

The Role of Mg(II) in DNA Cleavage Site Recognition in Group II Intron Ribozymes

The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations

The change of corrin-amides to carboxylates leads to altered structures of the B12-responding btuBriboswitch ⬇️

The corrin moiety of coenzyme B12 is the determinant for switching the btuB riboswitch of E. coli.

The structural stabilization of the κ three-way junction by Mg(II) represents the first step in the folding of a group II intron ⬇️

Unusually high-affinity Mg(2+) binding at the AU-rich sequence within the antiterminator hairpin of a Mg(2+) riboswitch.

Using in vitro transcription to construct scaffolds for one-dimensional arrays of mercuric ions.