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List of works by Mark T Ledwidge

A Central Role for Monocyte-Platelet Interactions in Heart Failure

scientific article

A comparison of HFrEF vs HFpEF's clinical workload and cost in the first year following hospitalization and enrollment in a disease management program

scientific article published on 23 December 2016

A systematic review of clinical prediction rules for the diagnosis of chronic heart failure

scientific article published on 10 March 2019

Are beta2-agonists responsible for increased mortality in heart failure?

scientific article published on August 2011

Aspirin use in heart failure: is low-dose therapy associated with mortality and morbidity benefits in a large community population?

scientific article published on 03 February 2014

Associates of an elevated natriuretic peptide level in stable heart failure patients: implications for targeted management.

scientific article published on 25 December 2013

Attenuation of monocyte chemotaxis--a novel anti-inflammatory mechanism of action for the cardio-protective hormone B-type natriuretic peptide.

scientific article published on 27 April 2013

B-Type Natriuretic Peptide and Ventricular Dysfunction in the Prediction of Cardiovascular Events and Death in Hypertension.

scientific article published on 4 October 2017

B-type natriuretic peptide measurement in primary care; magnitude of associations with cardiovascular risk factors and their therapies. Observations from the STOP-HF (St. Vincent's Screening TO Prevent Heart Failure) study.

scientific article published on 31 January 2011

Can emerging biomarkers of myocardial remodelling identify asymptomatic hypertensive patients at risk for diastolic dysfunction and diastolic heart failure? ⬇️

scientific article published on June 30, 2011

Can individualized weight monitoring using the HeartPhone algorithm improve sensitivity for clinical deterioration of heart failure?

scientific article published on 29 November 2012

Clinical and psychological impact of prophylactic implantable cardioverter-defibrillators in a community heart failure population.

scientific article

Clinical deterioration in established heart failure: what is the value of BNP and weight gain in aiding diagnosis?

scientific article published in October 2005

Cost-effectiveness of natriuretic peptide-based screening and collaborative care: a report from the STOP-HF (St Vincent's Screening TO Prevent Heart Failure) study

scientific article

Decompensation of chronic heart failure associated with pregabalin in patients with neuropathic pain

scientific article published on 01 April 2007

Developing a disease management program for the improvement of heart failure outcomes: the do's and the don'ts

scientific article published on 08 April 2019

Diabetes and complications of the heart in Sub-Saharan Africa: An urgent need for improved awareness, diagnostics and management

scientific article published on 26 December 2017

Diagnosis of heart failure with preserved ejection fraction: improved accuracy with the use of markers of collagen turnover.

scientific article published on February 2009

Diagnosis of new onset heart failure in the community: the importance of a shared-care approach and judicious use of BNP.

scientific article published on 17 July 2008

Diagnostics and therapeutic interventions in myocardial interstitial disease, a previously neglected pathology ⬇️

scientific article published on May 29, 2012

Diastolic heart failure: evidence of increased myocardial collagen turnover linked to diastolic dysfunction.

scientific article published on 5 February 2007

Differential inhibition of tumour cell‐induced platelet aggregation by the nicotinate aspirin prodrug (ST0702) and aspirin ⬇️

scientific article published on June 1, 2012

Disease management programs for heart failure: not just for the 'sick' heart failure population

scientific article published on 07 July 2006

Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled trial.

scientific article published on 5 February 2007

Elevated BNP with normal systolic function in asymptomatic individuals at-risk for heart failure: a marker of diastolic dysfunction and clinical risk.

scientific article published in October 2006

Elimination of early rehospitalization in a randomized, controlled trial of multidisciplinary care in a high-risk, elderly heart failure population: the potential contributions of specialist care, clinical stability and optimal angiotensin-convertin

scientific article published in March 2001

Epigenetic Therapy for the Treatment of Hypertension-Induced Cardiac Hypertrophy and Fibrosis.

scientific article

Exaggerated inflammation and monocytosis associate with diastolic dysfunction in heart failure with preserved ejection fraction: evidence of M2 macrophage activation in disease pathogenesis

scientific article published on 18 November 2014

Extracellular matrix sub-types and mechanical stretch impact human cardiac fibroblast responses to transforming growth factor beta

scientific article published on 08 April 2014

Getting to the heart of cardiac remodeling; how collagen subtypes may contribute to phenotype.

scientific article

Heart Failure Virtual Consultation: bridging the gap of heart failure care in the community - A mixed-methods evaluation.

scientific article

Heart Failure in Sub-Saharan Africa

article

Heart failure care in a hospital unit: a comparison of standard 3-month and extended 6-month programs.

scientific article

Heart failure in sub-Saharan Africa: review of the aetiology of heart failure and the role of point-of-care biomarker diagnostics

scientific article

Heart failure management programs: can we afford to ignore the inpatient phase of care?

scientific article

Heart failure management: multidisciplinary care has intrinsic benefit above the optimization of medical care

scientific article published on 01 June 2002

Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype.

scientific article

Importance of risk factor management in diabetic patients and reduction in Stage B heart failure

scientific article published on 19 September 2014

Improvement but no cure of left ventricular systolic dysfunction in treated heart failure patients.

scientific article

In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin?

scientific article published on 13 January 2012

Influence of diabetes on natriuretic peptide thresholds in screening for Stage B heart failure.

scientific article published on 6 April 2016

Intrauterine insemination-No more Mr. N.I.C.E. guy?

scientific article published on 18 January 2017

Late cardiac effects of chemotherapy in breast cancer survivors treated with adjuvant doxorubicin: 10-year follow-up.

scientific article published on 9 April 2016

Life expectancy for community-based patients with heart failure from time of diagnosis.

scientific article

Mechanisms of aggregation inhibition by aspirin and nitrate-aspirin prodrugs in human platelets

scientific article published on 10 November 2011

MicroRNA signatures differentiate preserved from reduced ejection fraction heart failure

scientific article published on 4 March 2015

Modest elevation in BNP in asymptomatic hypertensive patients reflects sub-clinical cardiac remodeling, inflammation and extracellular matrix changes.

scientific article

Multidisciplinary care of heart failure: what have we learned and where can we improve?

scientific article published on 01 December 2003

Multiple neurohumoral modulating agents in systolic dysfunction heart failure: are we lowering blood pressure too much?

scientific article published on 27 May 2008

Natriuretic Peptide-based Screening and Prevention of Heart Failure

scientific article published on 01 November 2017

Natriuretic peptide-based screening and collaborative care for heart failure: the STOP-HF randomized trial

scientific article published on July 2013

Natriuretic peptide-guided treatment for the prevention of cardiovascular events in patients without heart failure

scientific article published on 15 October 2019

Natural history of markers of collagen turnover in patients with early diastolic dysfunction and impact of eplerenone.

scientific article published in October 2009

Need and evolution of need for device therapy in a community heart failure population.

scientific article published on 21 May 2008

Nitric oxide-matrix metaloproteinase-9 interactions: biological and pharmacological significance--NO and MMP-9 interactions

scientific article

Nondipping Nocturnal Blood Pressure Predicts Sleep Apnea in Patients With Hypertension

scientific article published on 15 July 2019

Novel Iron-Whey Protein Microspheres Protect Gut Epithelial Cells from Iron-Related Oxidative Stress and Damage and Improve Iron Absorption in Fasting Adults.

scientific article published on 5 January 2018

Outpatient intravenous diuretic therapy; potential for marked reduction in hospitalisations for acute decompensated heart failure.

scientific article

Physicochemical characterization of diclofenac N-(2-hydroxyethyl)pyrrolidine: anhydrate and dihydrate crystalline forms

scientific article published on 01 January 1996

Profiling B-type natriuretic peptide in a stable heart failure population: a valuable adjunct to care.

scientific article

Progression of left atrial volume index in a population at risk for heart failure: a substudy of the STOP‐HF (St Vincent's Screening TO Prevent Heart Failure) trial ⬇️

scientific article published on July 3, 2012

Progression of preserved systolic function heart failure to systolic dysfunction -- a natural history study

scientific article published on 01 January 2006

Prospective analysis of LDL-C goal achievement and self-reported medication adherence among statin users in primary care.

scientific article published on 12 August 2011

Proteomic Analysis of Coronary Sinus Serum Reveals Leucine-Rich α2-Glycoprotein as a Novel Biomarker of Ventricular Dysfunction and Heart Failure ⬇️

scientific article published on January 31, 2011

Quality of life predicts outcome in a heart failure disease management program.

scientific article published on 12 October 2008

Role of Monitoring Devices in Preventing Heart Failure Admissions.

scientific article published on August 2015

Screening to prevent heart failure (STOP-HF): expanding the focus beyond asymptomatic left ventricular systolic dysfunction.

scientific article published on 13 March 2012

Serum Amyloid P-Component Prevents Cardiac Remodeling in Hypertensive Heart Disease

scientific article published on 17 November 2015

Specialist care of heart failure improves appropriate pharmacotherapy at the expense of greater polypharmacy and drug-interactions.

scientific article

Specialist nurse supervised in-hospital titration to target dose ACE inhibitor--is it safe and feasible in a community heart failure population?

scientific article published in September 2003

Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes

scientific article published on 01 March 2019

The Heart Failure Virtual Consultation - a powerful tool for the delivery of specialist care and the democratization of knowledge in the community

scientific article published on 28 December 2018

The St Vincent's potentially inappropriate medicines study: development of a disease-specific consensus list and its evaluation in ambulatory heart failure care.

scientific article published on August 2014

The prehospital patient pathway and experience of care with acute heart failure: a comparison of two health care systems

scientific article published on 24 December 2020

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