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List of works by Jan Johansson

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A membrane cell for on-line hydrogen/deuterium exchange to study protein folding and protein-protein interactions by mass spectrometry

scientific article

A method for S- and O-palmitoylation of peptides: synthesis of pulmonary surfactant protein-C models

scientific article published in November 1999

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

scientific article

A pH-dependent dimer lock in spider silk protein

A spidroin-derived solubility tag enables controlled aggregation of a designed amyloid protein

scientific article published on 31 March 2018

A synthetic surfactant based on a poly-Leu SP-C analog and phospholipids: effects on tidal volumes and lung gas volumes in ventilated immature newborn rabbits

scientific article published in August 2003

Alcohol dehydrogenases and aldehyde dehydrogenases

scientific article published on 01 June 1988

Alpha-helix targeting reduces amyloid-beta peptide toxicity

scientific article

Alterations of the C-terminal end do not affect in vitro or in vivo activity of surfactant protein C analogs.

scientific article published on 31 January 2011

Amino acid sequence determinants and molecular chaperones in amyloid fibril formation

scientific article published on May 2010

Amyloid Fibril Formation of Arctic Amyloid-β 1–42 Peptide is Efficiently Inhibited by the BRICHOS Domain

scientific article published in 2022

Amyloid beta-peptide aggregation. What does it result in and how can it be prevented?

scientific article published on January 2009

Amyloid fibril formation by pulmonary surfactant protein C

scientific article published on 01 December 1999

Amyloid-β-induced action potential desynchronization and degradation of hippocampal gamma oscillations is prevented by interference with peptide conformation change and aggregation

scientific article published in August 2014

Amyloid: a multifaceted player in human health and disease

scientific article

An amphipathic helical motif common to tumourolytic polypeptide NK-lysin and pulmonary surfactant polypeptide SP-B.

scientific article published in April 1995

Analysis of an inhibin preparation reveals apparent identity between a peptide with inhibin-like activity and a sperm-coating antigen

scientific article published on 01 October 1984

Anti-amyloid activity of the C-terminal domain of proSP-C against amyloid beta-peptide and medin

scientific article

Antibacterial activities of the cathelicidins prophenin (residues 62 to 79) and LL-37 in the presence of a lung surfactant preparation

scientific article

Antibacterial peptides in stimulated human granulocytes: characterization of ubiquitinated histone H1A.

scientific article

Arrest of beta-amyloid fibril formation by a pentapeptide ligand

scientific article published on 01 April 1996

Artificial surfactants based on analogues of SP-B and SP-C

scientific article

BRI2 ectodomain affects Aβ42 fibrillation and tau truncation in human neuroblastoma cells.

scientific article

BRICHOS - a superfamily of multidomain proteins with diverse functions

scientific article

BRICHOS - an anti-amyloid chaperone: evaluation of blood-brain barrier permeability of Bri2 BRICHOS.

scientific article published in March 2017

BRICHOS binds to a designed amyloid-forming β-protein and reduces proteasomal inhibition and aggresome formation

scientific article published on 17 November 2015

BRICHOS domain associated with lung fibrosis, dementia and cancer--a chaperone that prevents amyloid fibril formation?

scientific article published on 05 July 2011

BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells

scientific article published on 5 March 2018

BRICHOS domains efficiently delay fibrillation of amyloid β-peptide.

scientific article published on 16 July 2012

Biomimetic spinning of artificial spider silk from a chimeric minispidroin

scientific article published on 9 January 2017

Biomimicry of surfactant protein C.

scientific article published on 4 October 2008

Biophysical activity of an artificial surfactant containing an analogue of surfactant protein (SP)-C and native SP-B

scientific article

Biophysical and physiological properties of porcine surfactant enriched with polymyxin B.

scientific article

Blood-brain and blood-cerebrospinal fluid passage of BRICHOS domains from two molecular chaperones in mice

scientific article published on 31 December 2018

Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state

scientific article published on 12 December 2017

C-peptide binding to human cell membranes: importance of Glu27.

scientific article published in June 2001

C-peptide: a molecule balancing insulin states in secretion and diabetes-associated depository conditions

scientific article published on 18 June 2013

Canine hydrophobic surfactant polypeptide SP-C. A lipopeptide with one thioester-linked palmitoyl group

scientific article published on 01 April 1991

Carbonic anhydrase generates CO2 and H+ that drive spider silk formation via opposite effects on the terminal domains

scientific article

Carbonic anhydrase generates a pH gradient in Bombyx mori silk glands

scientific article published on 10 September 2015

Cellular antiendotoxin activities of lung surfactant protein C in lipid vesicles

scientific article published on 28 May 2003

Characterisation of variant forms of prophenin: mechanistic aspects of the fragmentation of proline-rich peptides

scientific article published on 01 January 2000

Charge attraction and beta propensity are necessary for amyloid fibril formation from tetrapeptides

scientific article published on 4 September 2002

Closely related isozymes of alcohol dehydrogenase. Carboxymethylation: gamma 1 gamma 1 differs widely from both beta 1 beta 1 and its equine equivalence EE

scientific article published on 01 February 1991

Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37

scientific article published on 01 February 1998

Conformational preferences of non-polar amino acid residues: an additional factor in amyloid formation

scientific article published on 28 October 2010

Control of amyloid assembly by autoregulation

scientific article published on October 2012

Current and future treatment of amyloid diseases

scientific article published on 10 May 2016

Cysteine reactivity in sorbitol and aldehyde dehydrogenases. Differences towards the pattern in alcohol dehydrogenase

scientific article published on May 25, 1992

Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis

scientific article

Degree of Biomimicry of Artificial Spider Silk Spinning Assessed by NMR Spectroscopy

scientific article published on 9 August 2017

Degree of Biomimicry of Artificial Spider Silk Spinning Assessed by NMR Spectroscopy

Dementia-related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits Aβ42 toxicity in Drosophila

scientific article

Different effects of surfactant proteins B and C - implications for development of synthetic surfactants

scientific article published on 10 June 2010

Dissociation of a BRICHOS trimer into monomers leads to increased inhibitory effect on Aβ42 fibril formation.

scientific article

Diversified Structural Basis of a Conserved Molecular Mechanism for pH-Dependent Dimerization in Spider Silk N-Terminal Domains

scientific article

Effects of Congo red on aβ(1-40) fibril formation process and morphology

scientific article published on 3 February 2010

Effects of ligands on unfolding of the amyloid β-peptide central helix: mechanistic insights from molecular dynamics simulations

scientific article

Efficient passage of human pluripotent stem cells on spider silk matrices under xeno-free conditions

scientific article published on October 2015

Efficient protein production inspired by how spiders make silk

scientific article

Electrophysiological evaluation of cystic fibrosis conductance transmembrane regulator (CFTR) expression in human monocytes.

scientific article published on 18 July 2014

Engineered disulfides improve mechanical properties of recombinant spider silk

scientific article published on May 2009

Evaluation of Functionalized Spider Silk Matrices: Choice of Cell Types and Controls are Important for Detecting Specific Effects

scientific article

Expression and characterization of saposin-like proteins

scientific article published on 01 August 1998

Folding and Intramembraneous BRICHOS Binding of the Prosurfactant Protein C Transmembrane Segment

scientific article published on 3 June 2015

Folding into a beta-hairpin can prevent amyloid fibril formation

scientific article published in April 2004

Full-length minor ampullate spidroin gene sequence

scientific article

Functionalisation of recombinant spider silk with conjugated polyelectrolytes

Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein

scientific article

Hereditary vascular dementia linked to notch 3 mutations. CADASIL in British families

scientific article

High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins.

scientific article published on 15 December 2017

High intracellular stability of the spidroin N-terminal domain in spite of abundant amyloidogenic segments revealed by in-cell hydrogen/deuterium exchange mass spectrometry

scientific article published on 09 December 2019

High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C.

scientific article

Human surfactant polypeptide SP-B. Disulfide bridges, C-terminal end, and peptide analysis of the airway form

scientific article

Hydrogen/deuterium exchange and aggregation of a polyvaline and a polyleucine alpha-helix investigated by matrix-assisted laser desorption ionization mass spectrometry

scientific article

Hydrolysis of the amyloid beta-peptide (A beta) 1-40 between Asp23-Val24 produces non-aggregating fragments. An electrospray mass spectrometric study

scientific article published in February 2005

Hydrophobic 3.7 kDa surfactant polypeptide: Structural characterization of the human and bovine forms ⬇️

scientific article published on May 9, 1988

Hydrophobic surfactant-associated polypeptides: SP-C is a lipopeptide with two palmitoylated cysteine residues, whereas SP-B lacks covalently linked fatty acyl groups

scientific article

Identification of hydrophobic bile proteins

scientific article published on 01 August 1998

Identification of hydrophobic fragments of alpha 1-antitrypsin and C1 protease inhibitor in human bile, plasma and spleen

scientific article published on 01 March 1992

Impact of synthetic surfactant CHF5633 with SP-B and SP-C analogues on lung function and inflammation in rabbit model of acute respiratory distress syndrome

scientific article published on 01 January 2021

Impaired CFTR function in mild cystic fibrosis associated with the S977F/T5TG12complex allele in trans with F508del mutation

scientific article published on 27 January 2013

In vitro ADMET and physicochemical investigations of poly-N-methylated peptides designed to inhibit Abeta aggregation

scientific article published on July 2010

Inactivation of pulmonary surfactant by silicone oil in vitro and in ventilated immature rabbits

scientific article published in May 2009

Insulin solubility transitions by pH-dependent interactions with proinsulin C-peptide

scientific article

Insulin, islet amyloid polypeptide and C-peptide interactions evaluated by mass spectrometric analysis

scientific article published on 01 January 2014

Interaction of pulmonary surfactant protein C with CD14 and lipopolysaccharide

scientific article

Invited review current progress and limitations of spider silk for biomedical applications

scientific article published on 06 September 2011

Isolation and characterization of hydrophobic polypeptides in human bile

scientific article

Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation

scientific article published on 24 March 2016

Lipopeptide preparation and analysis.

scientific article

Live-cell topology assessment of URG7, MRP6₁₀₂ and SP-C using glycosylatable green fluorescent protein in mammalian cells.

scientific article published on 15 July 2014

Low-molecular-mass surfactant protein type 1. The primary structure of a hydrophobic 8-kDa polypeptide with eight half-cystine residues

scientific article published on 01 March 1988

Macroscopic fibers self-assembled from recombinant miniature spider silk proteins

scientific article

Major ampullate spidroins from Euprosthenops australis: multiplicity at protein, mRNA and gene levels

scientific article published on 4 August 2007

Mass spectrometry captures structural intermediates in protein fiber self-assembly

scientific article

Membrane activity of (Cys48Ser) lung surfactant protein B increases with dimerisation

scientific article published on 01 June 2001

Mitochondrial aldehyde dehydrogenase from horse liver. Correlations of the same species variants for both the cytosolic and the mitochondrial forms of an enzyme

scientific article published on 01 March 1988

Molecular and cellular effects of C-peptide--new perspectives on an old peptide

scientific article published on January 2004

Molecular basis for amyloid fibril formation and stability

scientific article

Molecular dynamics studies of α-helix stability in fibril-forming peptides

article

Molecular effects of proinsulin C-peptide

scientific article

Molecular genetic characterisation of frontotemporal dementia on chromosome 3

scientific article (publication date: 1999)

Molecular structures and interactions of pulmonary surfactant components

scientific article published on March 1997

Morphology and composition of the spider major ampullate gland and dragline silk

scientific article published on 23 July 2013

Mutations linked to interstitial lung disease can abrogate anti-amyloid function of prosurfactant protein C.

scientific article

N-terminal nonrepetitive domain common to dragline, flagelliform, and cylindriform spider silk proteins

scientific article published on November 2006

N-terminally extended surfactant protein (SP) C isolated from SP-B-deficient children has reduced surface activity and inhibited lipopolysaccharide binding

scientific article published in April 2004

NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2

scientific article

Native-like Flow Properties of an Artificial Spider Silk Dope

scientific article published on 04 January 2021

Natural Derived Surfactant Preparation As a Carrier of Polymyxin E for Treatment of Pseudomonas aeruginosa Pneumonia in a Near-Term Rabbit Model

scientific article published on 19 October 2018

Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB

scientific article

Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease

scientific article

New developments in protein structure-function analysis by MS and use of hydrogen-deuterium exchange microfluidics

scientific article

New generation synthetic surfactants

scientific article published on 31 May 2013

New synthetic surfactant - how and when?

scientific article published on June 2006

New synthetic surfactants--basic science

scientific article

Novel expression of a functional trimeric fragment of human SP-A with efficacy in neutralisation of RSV.

scientific article

Novel stem/progenitor cells with neuronal differentiation potential reside in the leptomeningeal niche

scientific article published on 17 February 2009

Oligomerization and insulin interactions of proinsulin C-peptide: Threefold relationships to properties of insulin

scientific article published on 28 December 2009

Palmitoylation of a pulmonary surfactant protein C analogue affects the surface associated lipid reservoir and film stability

scientific article published on 01 June 2000

Peptide repertoire of human cerebrospinal fluid: novel proteolytic fragments of neuroendocrine proteins.

scientific article

Peptide-binding specificity of the prosurfactant protein C Brichos domain analyzed by electrospray ionization mass spectrometry

scientific article published in November 2009

Peptides of postulated inhibin activity

scientific article (publication date: 21 April 1986)

Peptides of postulated inhibin activity. Lack of in vitro inhibin activity of a 94-residue peptide isolated from human seminal plasma, and of a synthetic replicate of its C-terminal 28-residue segment

scientific article

Phospholipid Composition in Synthetic Surfactants Is Important for Tidal Volumes and Alveolar Stability in Surfactant-Treated Preterm Newborn Rabbits

scientific article

Poly-N-methylated amyloid beta-peptide (Abeta) C-terminal fragments reduce Abeta toxicity in vitro and in Drosophila melanogaster

scientific article published in December 2009

Porcine pulmonary surfactant preparations contain the antibacterial peptide prophenin and a C-terminal 18-residue fragment thereof

scientific article published on 01 October 1999

Prediction of amyloid fibril-forming proteins

scientific article published on 27 December 2000

Preventing amyloid formation by catching unfolded transmembrane segments

scientific article published on 16 April 2009

Processing of pulmonary surfactant protein B by napsin and cathepsin H

scientific article

Proinsulin C-peptide and insulin: Limited pattern similarities of interest in inter-peptide interactions but no C-peptide effect on insulin and IGF-1 receptor signaling

scientific article published on December 2006

Proinsulin C-peptide and its analogues induce intracellular Ca2+ increases in human renal tubular cells

scientific article published on 01 July 2002

Proinsulin C-peptide elicits disaggregation of insulin resulting in enhanced physiological insulin effects

scientific article published on August 2006

Proinsulin C-peptide interferes with insulin fibril formation

scientific article published on 18 January 2012

Prospects for a new synthetic surfactant

scientific article published on 01 January 2000

Protective effects of dimethyl sulfoxide on labile protein interactions during electrospray ionization

scientific article published on 24 April 2014

Protein Analogues in Artificial Surfactants ⬇️

scientific article published on January 1, 1997

Proteolytic generation and aggregation of peptides from transmembrane regions: lung surfactant protein C and amyloid beta-peptide

scientific article published on February 2004

Pulmonary surfactant from healthy Belgian White and Blue and Holstein Friesian calves: biochemical and biophysical comparison

scientific article published in January 2003

Pulmonary surfactant protein B: a structural model and a functional analogue

scientific article published on 01 June 2000

Pulmonary surfactant-associated polypeptide C in a mixed organic solvent transforms from a monomeric alpha-helical state into insoluble beta-sheet aggregates

scientific article published on December 1998

Pulmonary surfactant-associated polypeptide SP-C in lipid micelles: CD studies of intact SP-C and NMR secondary structure determination of depalmitoyl-SP-C(1-17)

scientific article published on 01 April 1995

Pulmonary surfactant: emerging protein analogues

scientific article published on February 1999

Recombinant spider silk as matrices for cell culture

scientific article

Recombinant spider silk genetically functionalized with affinity domains

scientific article published on 8 April 2014

Reverse-phase HPLC of the hydrophobic pulmonary surfactant proteins: detection of a surfactant protein C isoform containing Nepsilon-palmitoyl-lysine

scientific article published on September 1997

Role of C-peptide in human physiology

scientific article

Secondary structure and biophysical activity of synthetic analogues of the pulmonary surfactant polypeptide SP-C

scientific article published on April 1995

Secondary structure and limited proteolysis give experimental evidence that the precursor of pulmonary surfactant protein B contains three saposin-like domains

scientific article published on 01 February 1998

Secondary structure and membrane interaction of PR-39, a Pro+Arg-rich antibacterial peptide.

scientific article

Secondary structure and orientation of the surfactant protein SP-B in a lipid environment. A Fourier transform infrared spectroscopy study

scientific article published on September 29, 1992

Self-assembly of spider silk proteins is controlled by a pH-sensitive relay

scientific article

Separate functional features of proinsulin C-peptide

scientific article published on August 2005

Separate molecular determinants in amyloidogenic and antimicrobial peptides

scientific article published on 17 March 2014

Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation

scientific article

Silk Spinning in Silkworms and Spiders

scientific article

Size and structure of the hydrophobic low molecular weight surfactant-associated polypeptide

scientific article published in May 1988

Special issue: Protein structure and proteomics: introduction

scientific article published on 15 September 2011

Specific binding of proinsulin C-peptide to intact and to detergent-solubilized human skin fibroblasts

scientific article

Specific chaperones and regulatory domains in control of amyloid formation.

scientific article

Spider silk for xeno-free long-term self-renewal and differentiation of human pluripotent stem cells

scientific article

Spider silk proteins: recent advances in recombinant production, structure-function relationships and biomedical applications

scientific article published on 29 July 2010

Stabilization of discordant helices in amyloid fibril-forming proteins

scientific article published on May 2004

Sterilized recombinant spider silk fibers of low pyrogenicity

scientific article

Structural and functional importance of the C-terminal part of the pulmonary surfactant polypeptide SP-C

scientific article published on 01 April 1995

Structural and functional properties of pulmonary surfactant protein C and related analogs

scientific article published on 01 August 1998

Structural basis for interactions between lung surfactant protein C and bacterial lipopolysaccharide

scientific article published on 29 April 2002

Structural properties of recombinant nonrepetitive and repetitive parts of major ampullate spidroin 1 from Euprosthenops australis: implications for fiber formation

scientific article published in 2008

Structure and activity of cathelicidin antibacterial proteins

scientific article published on 01 August 1998

Structure and influence on stability and activity of the N-terminal propeptide part of lung surfactant protein C

scientific article

Structure and orientation of the surfactant-associated protein C in a lipid bilayer ⬇️

scientific article published on January 15, 1992

Superoxide dismutase in human testis preparations

scientific article published on 01 June 1986

Surface activity and film formation from the surface associated material of artificial surfactant preparations

scientific article

Surfactant protein B propeptide contains a saposin-like protein domain with antimicrobial activity at low pH

scientific article

Surfactant protein B: disulfide bridges, structural properties and kringle similarities ⬇️

scientific article published on July 16, 1991

Surfactant protein C in canine pulmonary fibrosis

scientific article published on 11 September 2009

Synthesis and evaluation of antineurotoxicity properties of an amyloid-β peptide targeting ligand containing a triamino acid

scientific article published in September 2014

Synthetic Surfactant Protein Analogues ⬇️

scientific article published on 01 September 1998

Synthetic peptide-containing surfactants--evaluation of transmembrane versus amphipathic helices and surfactant protein C poly-valyl to poly-leucyl substitution.

scientific article published in July 1998

Synthetic protein analogues in artificial surfactants

scientific article published on June 1996

Synthetic surfactant based on analogues of SP-B and SP-C is superior to single-peptide surfactants in ventilated premature rabbits

scientific article

Synthetic surfactants to treat neonatal lung disease

scientific article

Synthetic surfactants with SP-B and SP-C analogues to enable worldwide treatment of neonatal respiratory distress syndrome and other lung diseases

article

Systemic AA amyloidosis in the red fox (Vulpes vulpes).

scientific article

Targeting Alzheimer's Disease with Gene and Cell Therapies

scientific article published on 26 March 2018

The 21-residue surfactant peptide (LysLeu4)4Lys(KL4) is a transmembrane alpha-helix with a mixed nonpolar/polar surface

scientific article published on 01 April 1996

The BRICHOS domain, amyloid fibril formation, and their relationship

scientific article

The Brichos domain of prosurfactant protein C can hold and fold a transmembrane segment

scientific article

The Brichos domain-containing C-terminal part of pro-surfactant protein C binds to an unfolded poly-val transmembrane segment

scientific article (publication date: 28 July 2006)

The N-terminal propeptide of lung surfactant protein C is necessary for biosynthesis and prevents unfolding of a metastable alpha-helix

scientific article published in May 2004

The NMR structure of the pulmonary surfactant-associated polypeptide SP-C in an apolar solvent contains a valyl-rich alpha-helix

scientific article

The antimicrobial peptide LL-37 binds to the human plasma protein apolipoprotein A-I.

scientific article published in January 2004

The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogaster

scientific article

The extracellular domain of Bri2 (ITM2B) binds the ABri peptide (1-23) and amyloid beta-peptide (Abeta1-40): Implications for Bri2 effects on processing of amyloid precursor protein and Abeta aggregation

scientific article published on 28 December 2009

The palmitoyl groups of lung surfactant protein C reduce unfolding into a fibrillogenic intermediate

scientific article

The role of homodimers in surfactant protein B function in vivo

scientific article published on 01 February 2000

The structure, molecular interactions and bioactivities of proinsulin C-peptide correlate with a tripartite molecule

scientific article

Tissue Response to Subcutaneously Implanted Recombinant Spider Silk: An in Vivo Study

scientific article published on 20 November 2009

Toward spinning artificial spider silk

scientific article published on 17 April 2015

Transmissible amyloid

scientific article published on 22 March 2016

Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System

scientific article published on 15 March 2017

TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro

article published in 2018

Unfolding of the amyloid β-peptide central helix: mechanistic insights from molecular dynamics simulations

scientific article

Unordered structured of proinsulin C-peptide in aqueous solution and in the presence of lipid vesicles

scientific article published on 01 February 2000

Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37.

scientific article

Very low surfactant protein C contents in newborn Belgian White and Blue calves with respiratory distress syndrome

scientific article published on November 2000

pH-dependent dimerization of spider silk N-terminal domain requires relocation of a wedged tryptophan side chain

scientific article

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