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List of works by Claudia Giachino

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Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions

scientific article
Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy

scientific article
A New Paradigm in Cardiac Regeneration: The Mesenchymal Stem Cell Secretome

scientific article published on 5 May 2015
High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells

scientific article
A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia.

scientific article published in June 2008
Impaired elimination of DNA double-strand break-containing lymphocytes in ataxia telangiectasia and Nijmegen breakage syndrome.

scientific article
Human CD8 co–receptor is strictly involved in MHC–peptide tetramer–TCR binding and T cell activation

scientific article published on 01 January 2002
Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells.

scientific article
Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview

scientific article
T cell receptor (TCR) gene transfer with lentiviral vectors allows efficient redirection of tumor specificity in naive and memory T cells without prior stimulation of endogenous TCR.

scientific article
Dominant TCR-alpha requirements for a self antigen recognition in humans

scientific article (publication date: December 2002)
Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease

scientific article published on 28 January 2013
Molecular and functional bases of self-antigen recognition in long-term persistent melanocyte-specific CD8+ T cells in one vitiligo patient

scientific article published in August 2003
Melanocyte-specific, cytotoxic T cell responses in vitiligo: the effective variant of melanoma immunity?

scientific article
The effect of bioartificial constructs that mimic myocardial structure and biomechanical properties on stem cell commitment towards cardiac lineage

scientific article published on 4 October 2013
Fluorescent silica nanoparticles improve optical imaging of stem cells allowing direct discrimination between live and early-stage apoptotic cells.

scientific article
An in vitro model of T cell receptor revision in mature human CD8+ T cells.

scientific article
Qualitative difference between the cytotoxic T lymphocyte responses to melanocyte antigens in melanoma and vitiligo.

scientific article published on November 2005
Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process

scientific article published on 13 September 2017
Histone variants as emerging regulators of embryonic stem cell identity

scientific article
Diverse expansion potential and heterogeneous avidity in tumor-associated antigen-specific T lymphocytes from primary melanoma patients

scientific article published on 01 February 2001
Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells

scientific article
Unsuitability of lymphoblastoid cell lines as surrogate of cryopreserved isolated lymphocytes for the analysis of DNA double-strand break repair activity.

scientific article
Apelin-induced cardioprotection against ischaemia/reperfusion injury: roles of epidermal growth factor and Src.

scientific article published on 27 July 2017
Risk Assessment and Risk Minimization in Nanomedicine: A Need for Predictive, Alternative, and 3Rs Strategies

scientific article published on 13 March 2018
Analysis of secondary V(D)J rearrangements in mature, peripheral T cells of ataxia-telangiectasia heterozygotes.

scientific article published on October 2003
Involvement of MRE11A and XPA gene polymorphisms in the modulation of DNA double-strand break repair activity: a genotype-phenotype correlation study

scientific article
Silica nanoparticles actively engage with mesenchymal stem cells in improving acute functional cardiac integration

scientific article published on 01 May 2018
A novel defect in mitochondrial p53 accumulation following DNA damage confers apoptosis resistance in Ataxia Telangiectasia and Nijmegen Breakage Syndrome T-cells.

scientific article published on 14 October 2010
H2AX phosphorylation level in peripheral blood mononuclear cells as an event-free survival predictor for bladder cancer

scientific article published on 19 November 2015
Insights into the regulation of immunoglobulin light chain gene rearrangements via analysis of the kappa light chain locus in lambda myeloma

scientific article published in July 2004
Micro- and Macrostructured PLGA/Gelatin Scaffolds Promote Early Cardiogenic Commitment of Human Mesenchymal Stem Cells In Vitro

scientific article published on 16 October 2016
The cyclin-dependent kinase inhibitor 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole induces nongenotoxic, DNA replication-independent apoptosis of normal and leukemic cells, regardless of their p53 status

scientific article
Two-tier analysis of histone H2AX phosphorylation allows the identification of Ataxia Telangiectasia heterozygotes

scientific article published on 23 January 2009
Factors Ruling the Uptake of Silica Nanoparticles by Mesenchymal Stem Cells: Agglomeration Versus Dispersions, Absence Versus Presence of Serum Proteins

scientific article published on 16 February 2015
Cytotoxic T-lymphocyte responses in melanoma through in vitro stimulation with the Melan-A peptide analogue A27L: a qualitative analysis

article
Human mesenchymal stem cells labelled with dye-loaded amorphous silica nanoparticles: long-term biosafety, stemness preservation and traceability in the beating heart

scientific article
Transfer of efficient anti-melanocyte T cells from vitiligo donors to melanoma patients as a novel immunotherapeutical strategy

scientific article
TCR transfer induces TCR-mediated tonic inhibition of RAG genes in human T cells.

scientific article published on 8 April 2011
Effect of blood storage conditions on DNA repair capacity measurements in peripheral blood mononuclear cells

scientific article published on 30 May 2013
Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?

scholarly article by Lübeck Ralf Paus et al published February 2008 in Experimental Dermatology
Biodegradable microparticles designed to efficiently reach and act on cystic fibrosis mucus barrier

scientific article published on 18 October 2018
Cardioprotection of PLGA/gelatine cardiac patches functionalised with adenosine in a large animal model of ischaemia and reperfusion injury: A feasibility study

scientific article published on 31 May 2019
Nanocarriers as Magic Bullets in the Treatment of Leukemia

scientific article published on 06 February 2020
APJ as Promising Therapeutic Target of Peptide Analogues in Myocardial Infarction- and Hypertension-Induced Heart Failure

Dual Role of Autophagy in Regulation of Mesenchymal Stem Cell Senescence

scientific article published on 24 April 2020
The guidance of stem cell cardiomyogenic differentiation by bioartificial scaffolds mimicking myocardium structure and biomechanics.

scientific article published on 11 February 2014
Mediating Role of Lifestyle Behaviors in the Association between Education and Cancer: Results from the European Prospective Investigation into Cancer and Nutrition

Nanoengineering in Cardiac Regeneration: Looking Back and Going Forward

scientific article published on 12 August 2020
Silica Nanoparticle Internalization Improves Chemotactic Behaviour of Human Mesenchymal Stem Cells Acting on the SDF1α/CXCR4 Axis

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