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List of works by Julie Thoms

A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients.

scientific article

A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients ⬇️

scientific article published on August 2, 2010

A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.

scientific article published on 06 September 2016

A tropomyosin 1 induced defect in cytokinesis can be rescued by elevated expression of cofilin.

scientific article published on December 2008

Annotating Function to Differentially Expressed LincRNAs in Myelodysplastic Syndrome Using a Network-Based Method

scientific article published on 4 May 2017

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr ⬇️

scientific article published on February 2016

Constitutive CHK1 Expression Drives a pSTAT3-CIP2A Circuit that Promotes Glioblastoma Cell Survival and Growth

scientific article published on 20 February 2020

DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts

scientific article published on 14 August 2019

Disruption of a -35 kb Enhancer Impairs CTCF Binding and Expression in Colorectal Cells

scientific article published on 13 June 2018

ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.

scientific article published on 2 May 2011

Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif

scientific article published on December 2016

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes.

scientific article published on 23 August 2013

HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells

scientific article published on 01 February 2019

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

scientific article published on 23 August 2016

MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.

scientific article

OncoCis: annotation of cis-regulatory mutations in cancer

scientific article

Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells

scientific article published on 21 October 2014

Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias

scientific article

SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development

scientific article published on 13 April 2015

Systematic Screening of Promoter Regions Pinpoints Functional Cis-Regulatory Mutations in a Cutaneous Melanoma Genome

scientific article

Transcriptional networks in acute myeloid leukemia

scientific article published on 16 August 2019

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