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List of works by Rafael Linden

A conserved domain of the gp85/trans-sialidase family activates host cell extracellular signal-regulated kinase and facilitates Trypanosoma cruzi infection

scientific article published on 17 October 2006

A snapshot of gene therapy in Latin America

scientific article

A subacute model of glaucoma based on limbal plexus cautery in pigmented rats

scientific article published on 08 November 2019

ATP controls cell cycle and induces proliferation in the mouse developing retina.

scientific article published on 30 September 2009

Activation and function of murine primary microglia in the absence of the prion protein.

scientific article published on 10 July 2015

Advances in gene therapy technologies to treat retinitis pigmentosa.

scientific article published on 24 December 2013

Advances in recombinant adeno-associated viral vectors for gene delivery

scientific article

Allosteric function and dysfunction of the prion protein

scientific article published on 09 October 2011

Alternative programs of cell death in developing retinal tissue

scientific journal article

Antifungal Pisum sativum defensin 1 interacts with Neurospora crassa cyclin F related to the cell cycle

scientific article

Apoptosis Underlies Immunopathogenic Mechanisms in Acute Silicosis

scientific article published on 01 July 2002

Biosynthesis and metabolism of sulfated glycosaminoglycans during Drosophila melanogaster development.

scientific article published on 24 March 2004

CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system.

scientific article published on January 2014

Caspase dependence of the death of neonatal retinal ganglion cells induced by axon damage and induction of autophagy as a survival mechanism ⬇️

scientific article published on August 27, 2010

Cell death and interocular interactions among retinofugal axons: lack of binocularly matched specificity ⬇️

scientific article published on November 1, 1990

Cell death in the inner nuclear layer of the retina is modulated by BDNF.

scientific article published in December 2002

Cellular prion protein transduces neuroprotective signals

scientific article published on July 2002

Cellular prion protein: on the road for functions

scientific article

Chloramphenicol induces apoptosis in the developing brain

scientific article published on 01 July 2000

Control of programmed cell death by neurotransmitters and neuropeptides in the developing mammalian retina.

scientific article

De novo genesis of retinal ganglion cells by targeted expression of KLF4in vivo

scientific article published on 17 August 2018

De novo genesis of retinal ganglion cells by targeted expression of Klf4 in vivo

scientific article published on 21 August 2019

Development of abnormal lamination and binocular segregation in the retinotectal pathways of the rat

scientific article published on 01 October 1994

Differential effects of cyclin-dependent kinase blockers upon cell death in the developing retina.

scientific article published in August 2002

Displaced amacrine cells in the ganglion cell layer of the hamster retina

scientific article published on 01 January 1987

Does the use of recombinant AAV2 in pulmonary gene therapy damage lung function?

scientific article published on 14 September 2007

Endocytosis of prion protein is required for ERK1/2 signaling induced by stress-inducible protein 1.

scientific article published on June 2008

Evidence for an antiapoptotic role of dopamine in developing retinal tissue

scientific article published on 01 August 1999

Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2

scientific article published on 12 November 2018

Gap junctions mediate bystander cell death in developing retina

scientific article

Glutamate regulates retinal progenitors cells proliferation during development.

scientific article published on 21 August 2006

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hop/STI1 modulates retinal proliferation and cell death independent of PrPC

scientific article published in September 2007

Hydrogen peroxide induces caspase activation and programmed cell death in the amitochondrial Tritrichomonas foetus

scientific article published on 03 July 2003

Increased p53 and decreased p21 accompany apoptosis induced by ultraviolet radiation in the nervous system of a crustacean

scientific article published on 12 January 2016

Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways.

scientific article

Interleukin-4 blocks proliferation of retinal progenitor cells and increases rod photoreceptor differentiation through distinct signaling pathways.

scientific article published on 18 April 2008

Interleukin-4 blocks thapsigargin-induced cell death in rat rod photoreceptors: involvement of cAMP/PKA pathway

scientific article published in July 2009

Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain

scientific article published on 27 September 2010

NMDA receptor activation modulates programmed cell death during early post-natal retinal development: a BDNF-dependent mechanism

scientific article published in October 2005

Neuritogenesis and neuronal differentiation promoted by 2,4-dinitrophenol, a novel anti-amyloidogenic compound

scientific article published on October 2005

Neuritogenesis of retinal ganglion cells is differentially promoted by target extract

scientific article published on 01 December 1993

Neuroimmunoendocrine regulation of the prion protein in neutrophils

scientific article

Nuclear proteasomal degradation and cytoplasmic retention underlie early nuclear exclusion of transcription factor Max upon axon damage.

scientific article published on 14 June 2008

Paracrine interaction between bone marrow-derived stem cells and renal epithelial cells

scientific article published on 16 August 2011

Paracrine neuroprotective effect of nitric oxide in the developing retina.

scientific article

Physiology of the prion protein

scientific article

Pituitary adenylyl cyclase-activating polypeptide controls the proliferation of retinal progenitor cells through downregulation of cyclin D1.

scientific article published on 14 July 2010

Pituitary adenylyl cyclase-activating polypeptide prevents induced cell death in retinal tissue through activation of cyclic AMP-dependent protein kinase

scientific article published on 14 February 2002

Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition

scientific article

Pleiotropic functions of pituitary adenylyl cyclase-activating polypeptide on retinal ontogenesis: involvement of KLF4 in the control of progenitor cell proliferation.

scientific article

PrPc on the road: trafficking of the cellular prion protein

scientific article published on February 2004

Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice.

scientific article

Prion protein: orchestrating neurotrophic activities.

scientific article published on 18 September 2009

Protein kinases JAK and ERK mediate protective effect of interleukin-2 upon ganglion cells of the developing rat retina

scientific article published on 22 January 2011

Protein kinases selectively modulate apoptosis in the developing retina in vitro ⬇️

scientific article published on 01 August 1997

Rapid plasticity of intact axons following a lesion to the visual pathways during early brain development is triggered by microglial activation

article

Receptive field properties of single units in the opossum striate cortex

scientific article published on March 12, 1976

Receptive fields in the visual cortex of the opossum.

scientific article published in December 1973

Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STI1.

scientific article published on 24 August 2009

Reply to Altered Monoaminergic Systems and Depressive-like Behavior in Congenic Prion Protein Knock-out Mice.

scientific article published in October 2015

Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat

scientific article published on 27 September 2019

Rod photoreceptor cell death is induced by okadaic acid through activation of PKC and L-type voltage-dependent Ca2+ channels and prevented by IGF-1.

scientific article published on 11 May 2010

Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular and Alzheimer's diseases

scientific article published on 19 July 2020

STI1 promotes glioma proliferation through MAPK and PI3K pathways

scientific article published in December 2007

Selective involvement of the PI3K/PKB/bad pathway in retinal cell death.

scientific article published in August 2003

Signaling induced by hop/STI-1 depends on endocytosis

scientific article

Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

scientific article

Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice

scientific article published on 11 November 2019

The Biological Function of the Prion Protein: A Cell Surface Scaffold of Signaling Modules

scientific article published on 20 March 2017

The anti-death league: associative control of apoptosis in developing retinal tissue

scientific article published on 01 April 2000

The pretectal complex in the opossum: projections from the striate cortex and correlation with retinal terminal fields

scientific article published on 01 March 1981

The prion protein selectively binds to and modulates the content of purinergic receptor P2X4R.

scientific article published on 2 March 2016

The unconventional secretion of stress-inducible protein 1 by a heterogeneous population of extracellular vesicles

scientific article

Towards cellular receptors for prions

scientific article published on November 2003

Trophic factors produced by retinal cells increase the survival of retinal ganglion cells in vitro.

scientific article published in September 1993

rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia.

scientific article published on 31 December 2016

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