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List of works by Macdonald J Christie

Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human ⬇️

scientific article published on October 1, 2011

Cardiovascular effects of microinjections of opioid agonists into the `Depressor Region' of the ventrolateral periaqueductal gray region ⬇️

scientific article published on July 11, 1997

Characterisation of Na(v) types endogenously expressed in human SH-SY5Y neuroblastoma cells

scientific article

Chemical synthesis and structure of the prokineticin Bv8

scientific article

Conus Venom Peptide Pharmacology ⬇️

scientific article published on March 8, 2012

Developmental aspects of the locus coeruleus-noradrenaline system ⬇️

scientific article published on January 1, 1991

Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area ⬇️

scientific article published on June 6, 2011

Glutamate transporter dysfunction associated with nerve injury-induced pain in mice ⬇️

scientific article published on 09 November 2011

Inhibition of the norepinephrine transporter by χ-conotoxin dendrimers

scientific article published on 22 February 2016

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists

scientific article published on 31 March 2020

Mechanisms of opioid actions on neurons of the locus coeruleus ⬇️

scientific article published on January 1, 1991

Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons ⬇️

scientific article published on March 1, 2012

Method of sacrifice influences leucine enkephalin binding to mouse brain ⬇️

scientific article published on December 1, 1981

MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors

scientific article published on 30 December 2013

Multiple mechanisms of microglia: A gatekeeper's contribution to pain states ⬇️

scientific article published on January 16, 2012

Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization

scientific article published on 17 July 2018

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

scientific article published on May 2017

Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides

scientific article published in Scientific Reports

Opioid‐related (ORL1) receptors are enriched in a subpopulation of sensory neurons and prolonged activation produces no functional loss of surface N‐type calcium channels ⬇️

scientific article published on February 27, 2012

Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a

scientific article

Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects

scientific article published in Nature Communications

Positive allosteric mechanisms of adenosine A<sub>1</sub> receptor-mediated analgesia

scientific article published on 08 September 2021

Prolonged Stimulation of μ-Opioid Receptors Produces β-Arrestin-2-Mediated Heterologous Desensitization of α2-Adrenoceptor Function in Locus Ceruleus Neurons ⬇️

scientific article published on June 11, 2012

Sensitivity of morphine-tolerant rats to muscarinic and dopaminergic agonists: Relation to tolerance or withdrawal ⬇️

scientific article published on September 1, 1979

Swim-stress but not opioid withdrawal increases expression of c-Fos immunoreactivity in rat periaqueductal gray neurons which project to the rostral ventromedial medulla ⬇️

scientific article published on March 1, 1998

The correlation between swim-stress induced antinociception and [3H] leu-enkephalin binding to brain homogenates in mice ⬇️

scientific article published on December 1, 1981

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.

scientific article

Tolerance and cross tolerance with morphine resulting from physiological release of endogenous opiates ⬇️

scientific article published on August 30, 1982

Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-Assisted Folding

article

Transmitter regulation of voltage-dependent K+ channels expressed in Xenopus oocytes ⬇️

scientific article published on August 1, 1991

Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter

scientific article published on 24 September 2013

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