List of works by Claire-Anne Siegrist

A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog

A global perspective on vaccine safety and public health: The Global Advisory Committee on Vaccine Safety

research work

A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells

scientific article

A prospective study of the factors shaping antibody responses to the AS03-adjuvanted influenza A/H1N1 vaccine in cancer outpatients

scientific article

ABCB1 polymorphisms and neuropsychiatric adverse events in oseltamivir-treated children during influenza H1N1/09 pandemia

scientific article published on 8 September 2011

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

scientific article

AS03- and MF59-Adjuvanted Influenza Vaccines in Children

scientific article

Acceptability of maternal immunization against influenza: the critical role of obstetricians

scientific article published on 16 March 2012

Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant

scientific article

Aluminum hydroxide adjuvant induces macrophage differentiation towards a specialized antigen-presenting cell type.

scientific article published in August 2004

Antenatal vaccination to decrease pertussis in infants: safety, effectiveness, timing, and implementation

scientific article

Antibody responses to natural influenza A/H1N1/09 disease or following immunization with adjuvanted vaccines, in immunocompetent and immunocompromised children

article

Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection

scientific article published on 20 November 2015

Atorvastatin Treatment and Vaccination Efficacy

scientific article published on 04 June 2007

Attitudes of Swiss Health Care Providers Toward Childhood Immunizations

scientific article published on 27 December 2016

Author's reply

Autoimmune diseases after adolescent or adult immunization: what should we expect?

scientific article

B-cell responses to vaccination at the extremes of age.

scientific article published on March 2009

Blame vaccine interference, not neonatal immunization, for suboptimal responses after neonatal diphtheria, tetanus, and acellular pertussis immunization

scientific article published on 01 September 2008

Booster vaccination after neonatal priming with acellular pertussis vaccine

scientific article published in April 2010

Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes

scientific article published on 25 January 2016

CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles

scientific article published in January 2003

Can successful vaccines teach us how to induce efficient protective immune responses?

scientific article

Challenges in infant immunity: implications for responses to infection and vaccines

scientific article published on 01 March 2011

Chickenpox in a Swiss prison: Susceptibility, post-exposure vaccination and control measures

article

Clinical features and viral kinetics in a rapidly cured patient with Ebola virus disease: a case report

scientific article

Co-administration of CpG oligonucleotides enhances the late affinity maturation process of human anti-hepatitis B vaccine response

scientific article

Comment on "Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironment where plasmablasts mature".

scientific article published in May 2009

Comparison of clinical presentation of respiratory tract infections in H1N1/09-positive and H1N1/09-negative patients

scientific article published on 15 June 2011

Correlates of vaccine-induced protective immunity against Ebola virus disease

CpG-motifs enhance initial and sustained primary tetanus-specific antibody secreting cell responses in spleen and bone marrow, but are more effective in adult than in neonatal mice ⬇️

scientific article published on 01 June 2003

Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study

article by Angela Huttner et al published July 2018 in Lancet Infectious Diseases

Determinants of hepatitis A vaccine immunity in a cohort of human immunodeficiency virus-infected children living in Switzerland.

scientific article

Determinants of vaccine immunity in the cohort of human immunodeficiency virus-infected children living in Switzerland.

scientific article published in November 2009

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.

scientific article published on 7 February 2010

Diagnosis of whooping cough in Switzerland: differentiating Bordetella pertussis from Bordetella holmesii by polymerase chain reaction

scientific article published on 19 February 2014

Durability of single-dose rVSV-ZEBOV vaccine responses: what do we know?

article

Early appearance of bactericidal antibodies after polysaccharide challenge of toddlers primed with a group C meningococcal conjugate vaccine: what is its role in the maintenance of protection?

scientific article

Early life T cell responses to pneumococcal conjugates increase with age and determine the polysaccharide-specific antibody response and protective efficacy.

scientific article

Effect of month of vaccine administration on antibody responses in The Gambia and Pakistan

scientific article published on October 2006

Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials.

scientific article

Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells

scientific article published on 01 March 2002

Efficient orthogonal bioconjugation of dendrimers for synthesis of bioactive nanoparticles

scientific article published on 31 May 2011

Elevated inflammatory markers combined with positive pneumococcal urinary antigen are a good predictor of pneumococcal community-acquired pneumonia in children.

scientific article published in November 2013

Encephalitis associated with glutamic acid decarboxylase autoantibodies in a child: a treatable condition?

scientific article published on August 2011

Enhanced chickenpox exanthema in vaccine injection site

scientific article published on 01 January 2006

Enhanced pulmonary immunopathology following neonatal priming with formalin-inactivated respiratory syncytial virus but not with the BBG2NA vaccine candidate

scientific article published in June 2003

Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants

scientific article published on 16 November 2012

Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines

scientific article published on 24 February 2009

Frequent failure of adolescent booster responses to tetanus toxoid despite infant immunization: waning of infancy-induced immune memory?

scientific article published on 4 May 2010

Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life

scientific article

Generation of adult-like antibody avidity profiles after early-life immunization with protein vaccines

scientific article published in March 2002

Glycoconjugate vaccines and immune interference: A review

scientific article published on 25 June 2010

Graft-versus-host disease is the major determinant of humoral responses to the AS03-adjuvanted influenza A/09/H1N1 vaccine in allogeneic hematopoietic stem cell transplant recipients

scientific article

Haemophilus influenzae type b vaccine failure in children is associated with inadequate production of high-quality antibody.

scientific article published in January 2008

Health problems most commonly diagnosed among young female patients during visits to general practitioners and gynecologists in France before the initiation of the human papillomavirus vaccination program.

scientific article published on 3 November 2011

Hepatitis B immunisation induces higher antibody and memory Th2 responses in new-borns than in adults

scientific article published on 01 January 2004

Hepatitis B prevalence, risk factors, infection awareness and disease knowledge among inmates: a cross-sectional study in Switzerland's largest pre-trial prison

article

Higher memory responses in HIV-infected and kidney transplanted patients than in healthy subjects following priming with the pandemic vaccine

scientific article

Homing and adhesion patterns determine the cellular composition of the bone marrow plasma cell niche

scientific article published on 01 February 2012

How do physicians immunize their own children? Differences among pediatricians and nonpediatricians.

scientific article

Human papilloma virus immunization in adolescent and young adults: a cohort study to illustrate what events might be mistaken for adverse reactions

scientific article published in November 2007

Immunization and transplantation--what is new and what is coming?

scientific article

Immunogenicity and protective efficacy of neonatal vaccination against Bordetella pertussis in a murine model: evidence for early control of pertussis

scientific article

Immunomonitoring of human responses to the rVSV-ZEBOV Ebola vaccine

scientific article

Impact of synthetic and biologic disease-modifying antirheumatic drugs on antibody responses to the AS03-adjuvanted pandemic influenza vaccine: a prospective, open-label, parallel-cohort, single-center study

scientific article

Impaired antibody response causes persistence of prototypic T cell-contained virus

scientific article (publication date: 7 April 2009)

Importance of background rates of disease in assessment of vaccine safety during mass immunisation with pandemic H1N1 influenza vaccines

scientific article

Improvement of measles immunity among migrant populations: lessons learned from a prevalence study in a Swiss prison

article

Influence of Mycobacterium bovis Bacillus Calmette-Guerin on Antibody and Cytokine Responses to Human Neonatal Vaccination

article

Influence of complement C3 amount on IgG responses in early life: immunization with C3b-conjugated antigen increases murine neonatal antibody responses

scientific article published on 01 December 2004

Influenza vaccination given at least 2 weeks before delivery to pregnant women facilitates transmission of seroprotective influenza-specific antibodies to the newborn.

scientific article

Inhibition of B cell death causes the development of an IgA nephropathy in (New Zealand white x C57BL/6)F(1)-bcl-2 transgenic mice.

scientific article published in June 2004

Interpretation of primary care physicians' attitude regarding rotavirus immunisation using diffusion of innovation theories.

scientific article published on 21 June 2009

Intranasal immunization with pneumococcal conjugate vaccines with LT-K63, a nontoxic mutant of heat-Labile enterotoxin, as adjuvant rapidly induces protective immunity against lethal pneumococcal infections in neonatal mice

scientific article published on March 2002

Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor beta1 deficiency: medical and immunological implications

scientific article

MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life.

scientific article published on 13 April 2015

Maternal Immunization Earlier in Pregnancy Maximizes Antibody Transfer and Expected Infant Seropositivity Against Pertussis

scientific article published on 20 January 2016

Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants

scientific article

Memory B cell compartment constitution and susceptibility to recurrent lower respiratory tract infections in young children

scientific article published on 25 March 2013

Mode of action of adjuvants: implications for vaccine safety and design

scientific article published on 24 July 2010

Multimodal safety assessment of measles-mumps-rubella vaccination after pediatric liver transplantation

scholarly article by Laure F Pittet et al published 1 September 2018 in American Journal of Transplantation

Nasopharyngeal carriage of Streptococcus pneumoniae shortly before vaccination with a pneumococcal conjugate vaccine causes serotype-specific hyporesponsiveness in early infancy

scientific article

Needle-free and adjuvant-free epicutaneous boosting of pertussis immunity: Preclinical proof of concept

scientific article published on 9 June 2015

Neonatal immunization: where do we stand?

scientific article published on June 2011

Neonatal vaccination with an acellular pertussis vaccine accelerates the acquisition of pertussis antibodies in infants

scientific article published on 19 November 2007

Optimizing seroprotection against pneumococcus in children with nephrotic syndrome using the 13-valent pneumococcal conjugate vaccine

scientific article published on 26 August 2016

Overcoming the Neonatal Limitations of Inducing Germinal Centers through Liposome-Based Adjuvants Including C-Type Lectin Agonists Trehalose Dibehenate or Curdlan.

scientific article published on 28 February 2018

Partial activation of neonatal CD11c+ dendritic cells and induction of adult-like CD8+ cytotoxic T cell responses by synthetic microspheres.

scientific article published in August 2004

Pertussis Antibody Transfer to Preterm Neonates After Second- Versus Third-Trimester Maternal Immunization

scientific article

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe

scientific article

Pneumococcal polysaccharide vaccination in adults undergoing immunosuppressive treatment for inflammatory diseases--a longitudinal study

scientific article published on 6 June 2015

Predominant influence of environmental determinants on the persistence and avidity maturation of antibody responses to vaccines in infants

scientific article

Prevention of vertical HIV transmission

article

Protective anti-mycobacterial T cell responses through exquisitein vivo activation of vaccine-targeted dendritic cells

article

Protective antibody responses to influenza A/H1N1/09 vaccination in children with celiac disease

scientific article

Protective efficacy of individual CD8+ T cell specificities in chronic viral infection

scientific article

Protracted course of lymphocytic choriomeningitis virus WE infection in early life: induction but limited expansion of CD8+ effector T cells and absence of memory CD8+ T cells

scientific article published on 9 May 2007

Proximal splenic artery embolization for blunt splenic injury: clinical, immunologic, and ultrasound-Doppler follow-up

scientific article published on June 2007

Recurrence of cardiorespiratory events following repeat DTaP-based combined immunization in very low birth weight premature infants.

scientific article published in September 2008

Reduced ability of neonatal and early-life bone marrow stromal cells to support plasmablast survival.

scientific article

Response to treatment and disease progression linked to CD4+ T cell surface CC chemokine receptor 5 density in human immunodeficiency virus type 1 vertical infection

scientific article published in April 2002

Responses of solid organ transplant recipients to the AS03-adjuvanted pandemic influenza vaccine

scientific article

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries

scientific article

Safety and efficacy of immune-stimulating complex-based antigen delivery systems for neonatal immunisation against respiratory syncytial virus infection

scientific article published in June 2004

Safety and immunogenicity of a candidate bioconjugate vaccine against Shigella dysenteriae type 1 administered to healthy adults: A single blind, partially randomized Phase I study

scientific article published on 7 July 2015

Safety and immunogenicity of a combined Tetanus, Diphtheria, recombinant acellular Pertussis vaccine (TdaP) in healthy Thai adults

scientific article published on 29 September 2016

Safety and immunogenicity of rts,s+trap malaria vaccine, formulated in the as02a adjuvant system, in infant rhesus monkeys.

scientific article

Safety of DTaP-based combined immunization in very-low-birth-weight premature infants: frequent but mostly benign cardiorespiratory events.

scientific article published in July 2004

Seroprevalence of Bordetella pertussis antibodies in Flanders (Belgium).

scientific article published in June 2003

Successful induction of CD8 T cell-dependent protection against malaria by sequential immunization with DNA and recombinant poxvirus of neonatal mice born to immune mothers

scientific article published in September 2003

Swiss vaccinology update: new glycoconjugate vaccines against pneumococcal and meningococcal infections

scientific article published in January 2011

Synchronization of dendritic cell activation and antigen exposure is required for the induction of Th1/Th17 responses

scientific article

Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood

scientific article published on 11 January 2016

TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts

scientific article

Tetanus immunity as a surrogate for past diphtheria-tetanus-pertussis immunization in migrant children

scientific article published in March 2013

The 2014–2015 Ebola outbreak in West Africa: Hands On

scientific article

The Nucleoprotein Is Required for Lymphocytic Choriomeningitis Virus-Based Vaccine Vector Immunogenicity

scientific article published on 9 September 2015

The advantage of mucosal immunization for polysaccharide-specific memory responses in early life.

scientific article published in April 2005

The immunomodulating properties of human respiratory syncytial virus and immunostimulating complexes containing Quillaja saponin components QH-A, QH-C and ISCOPREP703.

scientific article

The magnitude of the antibody and memory B cell responses during priming with a protein-polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response.

scientific article published in February 2008

The next decade of vaccines: societal and scientific challenges

scientific article

Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children

Unresponsiveness to lymphoid-mediated signals at the neonatal follicular dendritic cell precursor level contributes to delayed germinal center induction and limitations of neonatal antibody responses to T-dependent antigens

scientific article published on 01 March 2003

Use of pneumococcal polysaccharide vaccine in children: what is the evidence?

scientific article published on June 2012

Vaccination and Autoimmunity

scholarly article published 28 January 2004

Vaccination during pregnancy to protect infants against influenza: why and why not?

scientific article published on 4 August 2011

Vaccination in early life: standing up to the challenges

scientific article published on 19 April 2016

Vaccination recommendations for adult patients with autoimmune inflammatory rheumatic diseases

scientific article published on 28 July 2015

Vaccine effectiveness in older individuals: What has been learned from the influenza-vaccine experience ⬇️

scientific article published on October 1, 2010

Vaccine safety controversies and the future of vaccination programs

scientific article

Vaccine update 2009: questions around the safety of the influenza A (H1N1) vaccine

scientific article published in January 2010

Vaccine-induced immunity in children after orthotopic liver transplantation: a 12-yr review of the Swiss national reference center.

scientific article published on February 2007

Volunteer feedback and perceptions after participation in a phase I, first-in-human Ebola vaccine trial: An anonymous survey

scientific article

What Is Wrong with Pertussis Vaccine Immunity? Inducing and Recalling Vaccine-Specific Immunity

scientific article published on 13 March 2017

Workshop on vaccine pressure and Neisseria meningitidis, Annecy, France, 9-11 March 2005

scientific article published on 19 March 2007

[Immunization and immuno-modulation for prevention of respiratory tract infections]

scientific article published on 01 November 2005

[Immunization guidelines in patients with chronic liver diseases]

scientific article published on 01 September 2007

[Prevention of influenza in acute care settings : a multimodal intervention].

scientific article

[Vaccine adjuvants and macrophagic myofasciitis].

scientific article published in January 2003

[Vaccinology, a new science at odds with beliefs]

scientific article published on 01 January 2005

[Vaccinology: which catch-up plans for patients with unknown or incomplete immunizations?]

scientific article published on 01 January 2009

[Why are boosters no longer necessary for protection against hepatitis B?].

scientific article published in March 2004

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