List of works - Jonathan N Pruneda

A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes

scientific article

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.

scientific article published on 19 October 2014

An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.

scientific article published on 13 November 2017

Assembly and specific recognition of k29- and k33-linked polyubiquitin.

scientific article

Development of Diubiquitin-Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

scientific article published on 21 March 2016

E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

scientific article

Evaluating enzyme activities and structures of DUBs

scientific article published on 22 February 2019

Functional Interactions of E2~ubiquitin Conjugates in and Outside the Ubiquitination Pathway ⬇️

doctoral thesis by Jonathan N. Pruneda, University of Washington, 2012

Identification and characterization of diverse OTU deubiquitinases in bacteria

scientific article published on 22 June 2020

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

scientific article published on 20 February 2018

Legionella dismantles linear ubiquitin

scientific article published on 01 August 2019

RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

scientific article

Structural and Functional Studies on the Interaction of GspC and GspD in the Type II Secretion System

scientific article

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

scientific article

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

scientific article published on 13 July 2016

The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence

scientific article published on 27 October 2016

Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.

scientific article published on 15 December 2016

Unraveling proteasome engagement

scientific article published on 15 June 2020

List of works by Jonathan N Pruneda

A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.

An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.

Assembly and specific recognition of k29- and k33-linked polyubiquitin.

Development of Diubiquitin-Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

Evaluating enzyme activities and structures of DUBs

Functional Interactions of E2~ubiquitin Conjugates in and Outside the Ubiquitination Pathway ⬇️

Identification and characterization of diverse OTU deubiquitinases in bacteria

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

Legionella dismantles linear ubiquitin

RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

Structural and Functional Studies on the Interaction of GspC and GspD in the Type II Secretion System

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence

Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.

Unraveling proteasome engagement