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List of works by Gerbrand J van der Heden van Noort

2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation

scientific article

A General Approach Towards Triazole-Linked Adenosine Diphosphate Ribosylated Peptides and Proteins

scientific article published on 7 December 2017

A general synthetic method toward uridylylated picornavirus VPg proteins.

scientific article published on 19 April 2013

A versatile one-pot procedure to phosphate monoesters and pyrophosphates using di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite.

scientific article

An RNA virus hijacks an incognito function of a DNA repair enzyme

scientific article

Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection

scientific article published on 13 November 2020

Chemical Tools to Study Protein ADP-Ribosylation

scientific article published on 22 January 2020

DNA-triggered dye transfer on a quantum dot.

scientific article published on 19 December 2013

Development of ADPribosyl ubiquitin analogs to study enzymes involved in Legionella infection

scientific article published on 19 October 2020

Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S

scientific article published on 01 March 2022

Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection

scientific article

Fully automated sequential solid phase approach towards viral RNA-nucleopeptides.

scientific article

Generation of the UFM1 Toolkit for Profiling UFM1-Specific Proteases and Ligases

scientific article published on 01 October 2018

How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling

scientific article published on 01 January 2019

Inhibition of papain-like protease PLpro blocks SARS-CoV-2 spread and promotes anti-viral immunity

scientific article published on 5 May 2020

K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap

scientific article published on 18 November 2020

Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

scientific article published on 07 December 2020

Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2

scientific article published on 26 August 2020

Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA.

scientific article

NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU)

scientific article

Nedd8 hydrolysis by UCH proteases in Plasmodium parasites.

scientific article published on 28 October 2019

Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets

scientific article

Novel class of OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection

scientific article published on 25 April 2020

One-Step Chemical Synthesis of Native Met1-Linked Poly-Ubiquitin Chains

scientific article published on 07 November 2018

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

scientific article published on 29 July 2020

Physicochemical property consensus sequences for functional analysis, design of multivalent antigens and targeted antivirals

scientific article

Profiling DUBs and Ubl-specific proteases with activity-based probes

scientific article published on 14 February 2019

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease

scientific article published on May 2016

Ribosylation of adenosine: an orthogonally protected building block for the synthesis of ADP-ribosyl oligomers.

scientific article

Sequence specificity for uridylylation of the viral peptide linked to the genome (VPg) of enteroviruses

scientific article published on 11 June 2015

Stereoselective ribosylation of amino acids

scientific article published on 24 April 2013

Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin Monomer.

scientific article published on 27 November 2017

Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitinating Enzyme SdeC

scientific article published on 18 May 2020

Synthesis of mono-ADP-ribosylated oligopeptides using ribosylated amino acid building blocks

scientific article published in April 2010

Synthesis of nucleotidylated poliovirus VPg proteins.

scientific article published on August 2010

Synthetic ubiquitinated proteins meet the proteasome: Distinct roles of ubiquitin in a chain

scientific article published on 29 March 2019