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List of works by Grégoire Altan-Bonnet

A Tunable Diffusion-Consumption Mechanism of Cytokine Propagation Enables Plasticity in Cell-to-Cell Communication in the Immune System.

scientific article

A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity

scientific article

Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells.

scientific article published on 12 March 2013

Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.

scientific article published in April 2006

Clonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion

scientific article published on January 2016

Clonal B cells in Waldenström's macroglobulinemia exhibit functional features of chronic active B-cell receptor signaling

scientific article published on 12 February 2016

Computational algorithm-driven evaluation of monocytic myeloid-derived suppressor cell frequency for prediction of clinical outcomes

scientific article

Correction: Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.

scientific article published on 14 March 2017

Cracking the NF-κB code

scientific article published on 18 February 2014

Cytokine-mediated communication: a quantitative appraisal of immune complexity

scientific article published on 01 April 2019

Dichotomy of cellular inhibition by small-molecule inhibitors revealed by single-cell analysis.

scientific article published on 30 September 2016

Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death.

scientific article published on 07 June 2013

EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines

scientific article published on 22 August 2017

Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1.

scientific article

IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus

scientific article published on 21 August 2019

Lymphocytic division clocked up by Myc.

scientific article published on 20 December 2016

Modeling of cytometry data in logarithmic space: When is a bimodal distribution not bimodal?

scientific article published on 16 February 2018

Monocyte recruitment and activated inflammation are associated with thyroid carcinogenesis in a mouse model

scientific article published on 01 July 2019

Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.

scientific article published on 29 January 2014

Perspectives for computer modeling in the study of T cell activation

scientific article

Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism.

scientific article published on 19 February 2013

Quantifying the Dynamics of Hematopoiesis by In Vivo IdU Pulse-Chase, Mass Cytometry, and Mathematical Modeling

scientific article published on 31 May 2019

Quantitative challenges in understanding ligand discrimination by alphabeta T cells

scientific article

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease.

scientific article published on 06 October 2008

Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response.

scientific article published on 30 March 2009

Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer

scientific article

Systematic investigation of cytokine signaling activity at the tissue and single-cell levels

scientific article published on 30 September 2021

T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens

scientific article published in May 2015

T cell receptor and IL-2 signaling strength control memory CD8<sup>+</sup> T cell functional fitness via chromatin remodeling

scientific article published on 26 April 2022

T cell responses to antigen: hasty proposals resolved through long engagements

scientific article

T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks

scientific article published on 09 April 2014

TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors

scientific article published on 11 September 2019

Universality of biochemical feedback and its application to immune cells

scientific article published on 01 February 2019