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List of works by Tatjana Eigenbrod

2'-O-Methylation within Bacterial RNA Acts as Suppressor of TLR7/TLR8 Activation in Human Innate Immune Cells.

scientific article published on 20 March 2015

2'-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms

scientific article published on 24 April 2019

A modified dinucleotide motif specifies tRNA recognition by TLR7.

scientific article published on 22 July 2014

Bacterial RNA Mediates Activation of Caspase-1 and IL-1β Release Independently of TLRs 3, 7, 9 and TRIF but Is Dependent on UNC93B ⬇️

scientific article published on May 25, 2012

Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses

scientific article

Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor 7.

scientific article published on 24 March 2017

Body fluid exosomes promote secretion of inflammatory cytokines in monocytic cells via Toll-like receptor signaling

scientific article published on 13 November 2013

Cell-contact dependent inhibition of monocytes by airway epithelial cells and reversion by infection with Respiratory Syncytial Virus

scientific article published on 27 June 2015

Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of and

scientific article published on 21 February 2019

Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation

scientific article published on 19 June 2009

Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells

scientific article published on December 2008

Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux

scientific article

DAMP signaling is a key pathway inducing immune modulation after brain injury.

scientific article

Double methylation of tRNA-U54 to 2'-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7

Early inhibition of IL-1β expression by IFN-γ is mediated by impaired binding of NF-κB to the IL-1β promoter but is independent of nitric oxide

scientific article published on 10 May 2013

Evaluation of antibiotic resistance to orally administrable antibiotics in staphylococcal bone and joint infections in one of the largest university hospitals in Germany: is there a role for fusidic acid?

scientific article

From macrophage to osteoclast - How metabolism determines function and activity

scientific article published on 18 June 2018

Identification of an optimized 2'-O-methylated trinucleotide RNA motif inhibiting Toll-like receptors 7 and 8.

scientific article published on 02 June 2017

Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity

scientific article published on 6 February 2012

Induction of tolerogenic lung CD4+ T cells by local treatment with a pSTAT-3 and pSTAT-5 inhibitor ameliorated experimental allergic asthma.

scientific article published on 6 December 2010

Inflammasomes as microbial sensors

scientific article published on March 2010

Influence of Pasteurella multocida Toxin on the differentiation of dendritic cells into osteoclasts.

scientific article

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

scientific article published on 30 October 2015

Interaction and Mutual Activation of Different Innate Immune Cells Is Necessary to Kill and Clear Hepatitis C Virus-Infected Cells

scientific article published on 29 September 2017

Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells

scientific article published on 11 May 2007

Molecular characterization of carbapenem-resistant Acinetobacter baumannii using WGS revealed missed transmission events in Germany from 2012-15

scientific article published on 01 December 2019

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

scientific article published on 08 January 2020

RNA Modifications Modulate Activation of Innate Toll-Like Receptors

Recognition of Specified RNA Modifications by the Innate Immune System

scientific article

Resection of small bowel adenocarcinoma liver metastasis combined with neoadjuvant and adjuvant chemotherapy results in extended disease-free period--a case report

scientific article published on 01 January 2006

TLR7 inhibition: A novel strategy for pancreatic cancer treatment?

scientific article published on January 2013

TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes

scientific article

The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.

scientific article

The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.

scientific article published in May 2005

The SiLuDrain Trial: a prospective randomized controlled trial comparing standard versus silver-impregnated lumbar drains

scientific article published on 01 June 2018

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