List of works - Stefan Siira

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.

scientific article published on 3 August 2016

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.

scientific article published on 05 August 2016

Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

scientific article

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

scientific article published on 6 August 2015

LRPPRC-mediated folding of the mitochondrial transcriptome

scientific article published on 16 November 2017

Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

scientific article published on 31 October 2013

Transcriptome-wide effects of a POLR3A gene mutation in patients with an unusual phenotype of striatal involvement

scientific article published on 9 August 2016

Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z

scientific article published on 20 August 2018

Simultaneous processing and degradation of mitochondrial RNAs revealed by circularized RNA sequencing

scientific article

Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

article

CirGO: an alternative circular way of visualising gene ontology terms

article

TEFM regulates both transcription elongation and RNA processing in mitochondria.

scientific article

Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.

scientific article published on 7 June 2018

Fidelity of translation initiation is required for coordinated respiratory complex assembly

scientific article published on 20 December 2019

Molecular basis of translation termination at noncanonical stop codons in human mitochondria

scientific article published on 04 May 2023

Computationally designed hyperactive Cas9 enzymes

scientific article published on 31 May 2022

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

scientific article published on 03 October 2019

A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance

scientific article published on 24 September 2021

Hyperactive Nickase Activity Improves Adenine Base Editing

scientific article published on 19 September 2024

Defects in RNA metabolism in mitochondrial disease

scientific article published on 8 February 2017

Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network

scientific article published on 21 December 2023

The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication

ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing

scientific article published on 30 September 2022

TANGO2 binds crystallin alpha B and its loss causes desminopathy

scientific article published on 6 June 2025

List of works by Stefan Siira

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.

Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

LRPPRC-mediated folding of the mitochondrial transcriptome

Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

Transcriptome-wide effects of a POLR3A gene mutation in patients with an unusual phenotype of striatal involvement

Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z

Simultaneous processing and degradation of mitochondrial RNAs revealed by circularized RNA sequencing

Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

CirGO: an alternative circular way of visualising gene ontology terms

TEFM regulates both transcription elongation and RNA processing in mitochondria.

Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.

Fidelity of translation initiation is required for coordinated respiratory complex assembly

Molecular basis of translation termination at noncanonical stop codons in human mitochondria

Computationally designed hyperactive Cas9 enzymes

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance

Hyperactive Nickase Activity Improves Adenine Base Editing

Defects in RNA metabolism in mitochondrial disease

Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network

The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication

ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing

TANGO2 binds crystallin alpha B and its loss causes desminopathy