List of works by Maria M. M. Santos

A More Sustainable Process for Preparation of the Muscarinic Acetylcholine Antagonist Umeclidinium Bromide

scientific article published on 31 August 2018

A tryptophanol-derived oxazolopiperidone lactam is cytotoxic against tumors via inhibition of p53 interaction with murine double minute proteins.

scientific article published on 23 March 2015

An Update on MDMX and Dual MDM2/X Inhibitors

scientific article published on 01 January 2018

Aspartic vinyl sulfones: Inhibitors of a caspase-3-dependent pathway

scientific article published on 05 March 2011

Biogenetically inspired enantioselective approach to Indolo[2,3-a]- and benzo[a]quinolizidine alkaloids from a synthetic equivalent of secologanin

scientific article published on 01 July 2005

Chemical Variations on the p53 Reactivation Theme

scientific article

DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties.

scientific article

Enantiopure Indolizinoindolones with in vitro Activity against Blood- and Liver-Stage Malaria Parasites

scientific article published on 3 November 2015

Enantiopure Indolo[2,3-a]quinolizidines: Synthesis and Evaluation as NMDA Receptor Antagonists.

scientific article

Enantioselective formal synthesis of (+)-dihydrocorynantheine and (-)-dihydrocorynantheol.

scientific article

Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline

scientific article published on 29 January 2013

Enantioselective spirocyclizations from tryptophanol-derived oxazolopiperidone lactams

scientific article published on 29 June 2007

Improving anticancer activity towards colon cancer cells with a new p53-activating agent

scientific article published on 06 September 2018

Indolo[2,3-a]quinolizidines and Derivatives: Bioactivity and Asymmetric Synthesis

scientific article published on 02 October 2015

In vitro targeting of colon cancer cells using spiropyrazoline oxindoles.

scientific article

Michael acceptors as cysteine protease inhibitors.

scientific article published on October 2007

Optimization of Bicyclic Lactam Derivatives as NMDA Receptor Antagonists

scientific article published on 20 February 2017

Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction.

scientific article published on 13 October 2014

Reaction of naphthoquinones with substituted nitromethanes. Facile synthesis and antifungal activity of naphtho[2,3-d]isoxazole-4,9-diones.

scientific article published on 4 November 2009

SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner

scientific article published on 17 January 2020

SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma

scientific article published on 10 August 2019

Spirotriazoline oxindoles: A novel chemical scaffold with in vitro anticancer properties

scientific article published on 21 September 2017

Squaric acid: a valuable scaffold for developing antimalarials?

article published in 2012

Straightforward Methodology for the Enantioselective Synthesis of Benzo[a]- and Indolo[2,3-a]quinolizidines

scientific article published on 05 June 2007

Synthesis and evaluation of spiroisoxazoline oxindoles as anticancer agents

scientific article published on 7 November 2013

Synthesis and evaluation of vinyl sulfones as caspase-3 inhibitors. A structure-activity study.

scientific article published on 24 May 2010

Tryptophanol-derived oxazolopiperidone lactams: identification of a hit compound as NMDA receptor antagonist.

scientific article published on 11 June 2014

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