List of works - Roberta De Simone

Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures

scientific article

Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction.

scientific article published on April 2004

Beneficial effects of enriched environment on adolescent rats from stressed pregnancies.

scientific article

Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals.

scientific article published on 9 February 2013

Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats

scientific article

Critical Role of Maternal Selenium Nutrition in Neurodevelopment: Effects on Offspring Behavior and Neuroinflammatory Profile

scientific article published in 2022

Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells

scientific article published on 04 November 2011

Docosahexaenoic acid promotes oligodendrocyte differentiation via PPAR-γ signalling and prevents tumor necrosis factor-α-dependent maturational arrest.

scientific article published on 21 June 2017

Effect of acetyl-L-carnitine on forebrain cholinergic neurons of developing rats

scientific article published on 01 January 1991

Fingolimod: A Disease-Modifier Drug in a Mouse Model of Amyotrophic Lateral Sclerosis.

scientific article published on 25 July 2016

Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 cells

scientific article published on 01 February 2000

Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells.

scientific article published on 21 November 2015

Inflammatory Signatures of Maternal Obesity as Risk Factors for Neurodevelopmental Disorders: Role of Maternal Microbiota and Nutritional Intervention Strategies

scientific article published in 2022

Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE

scientific article published on 01 December 1998

Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation

scientific article published on 18 January 2005

Microglial polarization and plasticity: evidence from organotypic hippocampal slice cultures.

scientific article published on 5 August 2013

NGF primed spleen cells injected in brain of developing rats differentiate into mast cells

scientific article published on 01 January 1989

NGF promotes microglial migration through the activation of its high affinity receptor: modulation by TGF-beta.

scientific article

Neonatal capsaicin exposure affects isolation-induced aggressive behavior and hypothalamic substance P levels of adult male mice (Mus musculus) ⬇️

scientific article published on April 1, 1993

Peroxisome proliferator activated receptor-γ agonists protect oligodendrocyte progenitors against tumor necrosis factor-alpha-induced damage: Effects on mitochondrial functions and differentiation.

scientific article published on 22 July 2015

Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves.

scientific article

Social status and nerve growth factor serum levels after agonistic encounters in mice.

scientific article published on January 1990

TGF‐β and LPS modulate ADP‐induced migration of microglial cells through P2Y1 and P2Y12 receptor expression ⬇️

scientific article published on August 30, 2010

The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.

scientific article

The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca2+ waves.

scientific article published on December 2013

List of works by Roberta De Simone

Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures

Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction.

Beneficial effects of enriched environment on adolescent rats from stressed pregnancies.

Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals.

Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats

Critical Role of Maternal Selenium Nutrition in Neurodevelopment: Effects on Offspring Behavior and Neuroinflammatory Profile

Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells

Docosahexaenoic acid promotes oligodendrocyte differentiation via PPAR-γ signalling and prevents tumor necrosis factor-α-dependent maturational arrest.

Effect of acetyl-L-carnitine on forebrain cholinergic neurons of developing rats

Fingolimod: A Disease-Modifier Drug in a Mouse Model of Amyotrophic Lateral Sclerosis.

Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 cells

Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells.

Inflammatory Signatures of Maternal Obesity as Risk Factors for Neurodevelopmental Disorders: Role of Maternal Microbiota and Nutritional Intervention Strategies

Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE

Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation

Microglial polarization and plasticity: evidence from organotypic hippocampal slice cultures.

NGF primed spleen cells injected in brain of developing rats differentiate into mast cells

NGF promotes microglial migration through the activation of its high affinity receptor: modulation by TGF-beta.

Neonatal capsaicin exposure affects isolation-induced aggressive behavior and hypothalamic substance P levels of adult male mice (Mus musculus) ⬇️

Peroxisome proliferator activated receptor-γ agonists protect oligodendrocyte progenitors against tumor necrosis factor-alpha-induced damage: Effects on mitochondrial functions and differentiation.

Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves.

Social status and nerve growth factor serum levels after agonistic encounters in mice.

TGF‐β and LPS modulate ADP‐induced migration of microglial cells through P2Y1 and P2Y12 receptor expression ⬇️

The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.

The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca2+ waves.