Search filters

List of works by Yves Mechulam

A Minimal Sequence for Left-Handed G-Quadruplex Formation

scientific article published on 21 January 2019

A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis

scientific article

Adaptive landscape flattening allows the design of both enzyme: Substrate binding and catalytic power

scientific article published on 09 January 2020

Capturing the mutational landscape of the beta-lactamase TEM-1.

scientific article published on 22 July 2013

Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features

scientific article

Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation

scientific article published on 06 February 2020

Cryo-EM study of start codon selection during archaeal translation initiation

scientific article

Crystal structure at 1.2Aresolution and active site mapping of Escherichia coli peptidyl-tRNA hydrolase ⬇️

scientific article published on August 1, 1997

Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features

scientific article

Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.

scientific article

Crystallization and preliminary X-ray analysis of Escherichia coli methionyl-tRNAMet(f) formyltransferase complexed with formyl-methionyl-tRNAMet(f)

scientific article published on 01 January 1999

Crystallization and preliminary X-ray analysis of Escherichia coli peptidyl-tRNA hydrolase.

scientific article published on May 1997

Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo

scientific article published on 17 August 2009

Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier.

scientific article published on January 2010

Fast purification of a functional elongator tRNAmetexpressed from a synthetic genein vivo ⬇️

scientific article published on August 25, 1988

General structure/function properties of microbial methionyl-tRNA synthetases.

scientific article

Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.

scientific article

Interplay of Methionine tRNAs with Translation Elongation Factor Tu and Translation Initiation Factor 2 in Escherichia coli

scientific article published in Journal of Biological Chemistry

Lysine 335, part of the KMSKS signature sequence, plays a crucial role in the amino acid activation catalysed by the methionyl-tRNA synthetase from Escherichia coli ⬇️

scientific article published on 01 February 1991

Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.

scientific article

Methionyl-tRNA synthetase needs an intact and mobile 332KMSKS336 motif in catalysis of methionyl adenylate formation.

scientific article

Mitochondrial methionyl-tRNAfMet formyltransferase from Saccharomyces cerevisiae: gene disruption and tRNA substrate specificity.

scientific article

Protection-based assays to measure aminoacyl-tRNA binding to translation initiation factors

scientific article published on 01 January 2007

Receptor site for the 5'-phosphate of elongator tRNAs governs substrate selection by peptidyl-tRNA hydrolase

scientific article published on 01 April 1999

Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex

scientific article published on 03 October 2019

Role of aIF1 in Pyrococcus abyssi translation initiation

scientific article published on 01 November 2018

Role of the 1-72 base pair in tRNAs for the activity of Escherichia coli peptidyl-tRNA hydrolase.

scientific article

Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA.

scientific article published on 27 November 2012

Start Codon Recognition in Eukaryotic and Archaeal Translation Initiation: A Common Structural Core

scientific article published on 21 February 2019

Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases

scientific article

Structural basis for partition of the cyclodipeptide synthases into two subfamilies.

scientific article published on 2 March 2018

Structural basis for tRNA-dependent amidotransferase function.

scientific article

Structural basis of RNA-dependent recruitment of glutamine to the genetic code

scientific article

Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates

scientific article published on 17 July 2020

Structural switch of the gamma subunit in an archaeal aIF2 alpha gamma heterodimer.

scientific article published in January 2006

Structure of a left-handed DNA G-quadruplex

scientific article

Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states

scientific article

Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases

scientific article

Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA

scientific article

Structure-function relationships of the intact aIF2alpha subunit from the archaeon Pyrococcus abyssi

scientific article published on 01 June 2005

The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.

scientific article

The many routes of bacterial transfer RNAs after aminoacylation.

scientific article

The structure of an E. coli tRNAfMet A1-U72 variant shows an unusual conformation of the A1-U72 base pair.

scientific article published on 31 January 2017

The trimeric coiled-coil HSBP1 protein promotes WASH complex assembly at centrosomes

scientific article published on 29 May 2018

Three-dimensional structure of methionyl-tRNA synthetase from Pyrococcus abyssi.

scientific article published in March 2004

Translation Initiation

scientific article published on 01 December 2011

Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases

scientific article

tRNA binding properties of eukaryotic translation initiation factor 2 from Encephalitozoon cuniculi

scientific article published on 15 September 2010

Paulina is supported by:

About Paulina

Help