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List of works by Kerstin Lindblad-Toh

28-way vertebrate alignment and conservation track in the UCSC Genome Browser

scientific article (publication date: December 2007)

A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs

scientific article (publication date: 10 May 2016)

A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12.

scientific article published on 11 August 2015

A Second-Generation Association Study of the 5q31 Cytokine Gene Cluster and the Interleukin-4 Receptor in Asthma

article

A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse

scientific article

A comprehensive genomic history of extinct and living elephants

scientific article published on 26 February 2018

A cytogenetically characterized, genome-anchored 10-Mb BAC set and CGH array for the domestic dog.

scientific article published on 16 August 2007

A deletion in nephronophthisis 4 (NPHP4) is associated with recessive cone-rod dystrophy in standard wire-haired dachshund

scientific article published on 7 August 2008

A deletion in the N-myc downstream regulated gene 1 (NDRG1) gene in Greyhounds with polyneuropathy

scientific article (publication date: 2010)

A frameshift mutation in golden retriever dogs with progressive retinal atrophy endorses SLC4A3 as a candidate gene for human retinal degenerations

scientific article published in 2011

A genome assembly-integrated dog 1 Mb BAC microarray: a cytogenetic resource for canine cancer studies and comparative genomic analysis

scientific article

A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies

scientific article

A high-resolution map of human evolutionary constraint using 29 mammals

scientific article

A missense mutation in the SERPINH1 gene in Dachshunds with osteogenesis imperfecta

scientific article published in July 2009

A mutation in hairless dogs implicates FOXI3 in ectodermal development

scientific article

A novel unstable duplication upstream of HAS2 predisposes to a breed-defining skin phenotype and a periodic fever syndrome in Chinese Shar-Pei dogs

scientific article

A population study of a mutation allele associated with cone-rod dystrophy in the standard wire-haired dachshund

scientific article

A quantitative framework for characterizing the evolutionary history of mammalian gene expression

article

A quantitative model for characterizing the evolutionary history of mammalian gene expression

article

A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

scientific article published on 20 November 2018

A simple repeat polymorphism in the MITF-M promoter is a key regulator of white spotting in dogs

scientific article

A splice site mutation in a gene encoding for PDK4, a mitochondrial protein, is associated with the development of dilated cardiomyopathy in the Doberman pinscher

scientific article published on 25 March 2012

A synonymous germline variant in a gene encoding a cell adhesion molecule is associated with cutaneous mast cell tumour development in Labrador and Golden Retrievers

scientific article published on 22 March 2019

A truncating mutation in ATP13A2 is responsible for adult-onset neuronal ceroid lipofuscinosis in Tibetan terriers.

scientific article

A unique T cell receptor discovered in marsupials

scholarly article

Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

scientific article

Amylase activity is associated with AMY2B copy numbers in dog: implications for dog domestication, diet and diabetes

scientific article

An Improved microRNA Annotation of the Canine Genome

scientific article (publication date: 2016)

An exome sequencing based approach for genome-wide association studies in the dog.

scientific article published on 15 November 2017

An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts

scientific article

An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing

scientific article (publication date: 29 March 2005)

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

scientific article published in June 2007

Analysis of a set of Australian northern brown bandicoot expressed sequence tags with comparison to the genome sequence of the South American grey short tailed opossum

scientific article published on 13 February 2007

Aquatic Adaptation and Depleted Diversity: A Deep Dive into the Genomes of the Sea Otter and Giant Otter

scientific article published on 01 December 2019

Assessing DNA sequence variations in human ESTs in a phylogenetic context using high-density oligonucleotide arrays

scientific article published in September 2002

Assisted assembly: how to improve a de novo genome assembly by using related species

scientific article (publication date: 2009)

BarkBase: Epigenomic Annotation of Canine Genomes

scientific article published on 07 June 2019

Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates

scientific article published on 18 April 2020

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

scientific article published on 21 August 2020

Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder

scientific article

Canine hereditary ataxia in old english sheepdogs and gordon setters is associated with a defect in the autophagy gene encoding RAB24

scientific article (publication date: February 2014)

Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden.

scientific article published on 30 May 2018

Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma

scientific article published on 30 September 2019

Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs ⬇️

Comparative physical maps derived from BAC end sequences of tilapia (Oreochromis niloticus)

scientific article

Comparison of buccal and blood-derived canine DNA, either native or whole genome amplified, for array-based genome-wide association studies

scientific article

Comparison of cellular location and expression of Plakophilin-2 in epidermal cells from nonlesional atopic skin and healthy skin in German shepherd dogs

scientific article

Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies

scientific article published on 08 December 2016

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

scientific article published in December 2005

Convergent evolution of the genomes of marine mammals

scientific article published on 26 January 2015

Copy number expansion of the STX17 duplication in melanoma tissue from Grey horses

scientific article

Correction: DLA Class II Alleles Are Associated with Risk for Canine Symmetrical Lupoid Onychodystrophy (SLO).

scientific article published on 23 September 2010

Correction: Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency

scientific article published on 14 September 2015

Correction: Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis

scientific article published on 11 December 2015

Correction: Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis.

scientific article published on 16 May 2013

Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.

scientific article published in May 2016

Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1

scientific article published on 01 January 2018

DLA class II alleles are associated with risk for canine symmetrical lupoid onychodystrophy [corrected](SLO).

scientific article

Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome

scientific article published on 17 October 2011

Diabetes mellitus in elkhounds is associated with diestrus and pregnancy

scientific article published on November 2010

Dissecting evolution and disease using comparative vertebrate genomics

scientific article

Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk

scientific article

Distinguishing protein-coding and noncoding genes in the human genome

scientific article

Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs

scientific article

Efficient mapping of mendelian traits in dogs through genome-wide association

scientific article

Evaluation of the serotonergic genes htr1A, htr1B, htr2A, and slc6A4 in aggressive behavior of golden retriever dogs

scientific article

Evolution of genes and genomes on the Drosophila phylogeny

scientific article

Evolutionary constraint and innovation across hundreds of placental mammals

scientific article published on 28 April 2023

Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background

scientific article published on 16 September 2015

Exploiting nucleotide composition to engineer promoters

scientific article

Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease

scientific article published on 2 November 2016

FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome

scientific article

Facilitating genome navigation: survey sequencing and dense radiation-hybrid gene mapping

scientific article published in August 2005

Fine-mapping and mutation analysis of TRPM1: a candidate gene for leopard complex (LP) spotting and congenital stationary night blindness in horses

article

Full-length transcriptome assembly from RNA-Seq data without a reference genome

scientific article

Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome

scientific article published on 21 August 2020

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype

scientific article

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

scientific article

Genome reannotation of the lizard Anolis carolinensis based on 14 adult and embryonic deep transcriptomes ⬇️

scientific article

Genome sequence, comparative analysis and haplotype structure of the domestic dog

scientific article

Genome sequence, comparative analysis, and population genetics of the domestic horse

scientific article

Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency

scientific article published on 30 July 2015

Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours.

scientific article

Genome-Wide Analysis of Long Non-Coding RNA Profiles in Canine Oral Melanomas

scientific article published on 23 June 2019

Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours

scientific article published on 20 November 2015

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

scientific article

Genome-wide analysis in German shepherd dogs reveals association of a locus on CFA 27 with atopic dermatitis

scientific article

Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis ⬇️

scientific article

Genome-wide association identifies a deletion in the 3' untranslated region of striatin in a canine model of arrhythmogenic right ventricular cardiomyopathy

scientific article published on 2 July 2010

Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex

article

Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers

scientific article

Genome-wide copy number variant discovery in dogs using the CanineHD genotyping array

scientific article

Genome-wide synteny through highly sensitive sequence alignment: Satsuma

scientific article

Genomic maps and comparative analysis of histone modifications in human and mouse

scientific article (publication date: 28 January 2005)

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma

scientific article

Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions

scientific article published on 01 March 2021

Heart development in fibronectin-null mice is governed by a genetic modifier on chromosome four

scientific article published on 02 June 2007

High prevalence of gait abnormalities in pugs

scientific article published on 5 February 2018

High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.

scientific article

How to make a rodent giant: Genomic basis and tradeoffs of gigantism in the capybara, the world's largest rodent

How to make a rodent giant: Genomic basis and tradeoffs of gigantism in the capybara, the world's largest rodent

scientific article published on 10 November 2020

ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

scientific article published on 19 March 2018

Identification and Classification of Conserved RNA Secondary Structures in the Human Genome

scientific article published on 07 March 2006

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

scientific article published in June 2007

Identification and classification of conserved RNA secondary structures in the human genome

scientific article

Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping

scientific article

Identification of repetitive elements in the genome of Oreochromis niloticus: tilapia repeat masker.

scientific article

Identification of the bovine Arachnomelia mutation by massively parallel sequencing implicates sulfite oxidase (SUOX) in bone development

scientific article

Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization.

scientific article published on 11 February 2014

IgA deficiency in wolves

scientific article published on 22 January 2013

Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes

scientific article published on 3 August 2015

Inheritance, Mode of Inheritance, and Candidate Genes for Primary Hyperparathyroidism in Keeshonden

scientific article published on 01 January 2007

Inheritance, Mode of Inheritance, and Candidate Genes for Primary Hyperparathyroidism in Keeshonden

Initial sequence and comparative analysis of the cat genome

scientific article

Initial sequencing and comparative analysis of the mouse genome

scientific article

Insights into mammalian TE diversity through the curation of 248 genome assemblies ⬇️

Integrated cytogenetic BAC map of the genome of the gray, short-tailed opossum, Monodelphis domestica

scientific article published on 10 May 2007

Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder

scientific article published on 17 October 2017

Integrating gene annotation with orthology inference at scale ⬇️

scientific article published on 28 April 2023

Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype

scientific article

Jagged1 as a modifier of the DMD phenotype: What is next?

LGI2 truncation causes a remitting focal epilepsy in dogs

scientific article

LUPA: a European initiative taking advantage of the canine genome architecture for unravelling complex disorders in both human and dogs

scientific article published on 12 July 2011

Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus

scientific article

Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse

article by Kerstin Lindblad-Toh et al published April 2000 in Nature Genetics

Leader of the pack: gene mapping in dogs and other model organisms

scientific article published on September 2008

Lineage-specific biology revealed by a finished genome assembly of the mouse

scientific article

Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds

scientific article

Localization of canine brachycephaly using an across breed mapping approach

scientific article

Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays

scientific article published on 01 September 2000

Low guanylyl cyclase activity in Weddell seals: implications for peripheral vasoconstriction and perfusion of the brain during diving

scientific article published on 20 March 2019

Mammary tumor development in dogs is associated with BRCA1 and BRCA2.

scientific article published on 3 November 2009

Microarray-based cytogenetic profiling reveals recurrent and subtype-associated genomic copy number aberrations in feline sarcomas

scientific article published on 26 November 2009

Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

scientific article published on 09 October 2020

Molecular profiling reveals prognostically significant subtypes of canine lymphoma

scientific article

Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach

scientific article

Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease

scientific article published on 9 June 2015

Multiple regulatory variants located in cell type-specific enhancers within the PKP2 locus form major risk and protective haplotypes for canine atopic dermatitis in German shepherd dogs

scientific article

Mutation discovery in mice by whole exome sequencing

scientific article published on 14 September 2011

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

scientific article

Nordic OCD & Related Disorders Consortium: Rationale, design, and methods

scientific article published on 19 August 2019

Novel origins of copy number variation in the dog genome

scientific article

Origins of shared genetic variation in African cichlids

scientific article published on 28 December 2012

Patterns of molecular genetic variation among cat breeds

scientific article published on 25 October 2007

Performance of microarray and liquid based capture methods for target enrichment for massively parallel sequencing and SNP discovery

scientific article

Progress in sequencing the mouse genome

article

Progressive Cactus is a multiple-genome aligner for the thousand-genome era

scientific article published on 11 November 2020

Progressive alignment with Cactus: a multiple-genome aligner for the thousand-genome era

scientific article published on 9 August 2019

Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication

scientific article

Refining tumor-associated aneuploidy through 'genomic recoding' of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas

scientific article

Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses

scientific article published on 21 December 2015

Repeat expansion detection (RED) and the RED cloning strategy

scientific article published on 01 January 2003

Rethinking dog domestication by integrating genetics, archeology, and biogeography

scientific article

SBE-TAGS: an array-based method for efficient single-nucleotide polymorphism genotyping

scientific article

SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma

scientific article published on 03 May 2018

Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR.

scientific article published on 13 February 2017

Sequencing the nuclear genome of the extinct woolly mammoth

scientific article

Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals

scientific article published on 26 November 2019

Standards recommendations for the Earth BioGenome Project

scientific article published on 18 January 2022

SweHLA: the high confidence HLA typing bio-resource drawn from 1000 Swedish genomes

scientific article published on 16 December 2019

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites

scientific article

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

scientific article

Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort

scientific article published on 09 November 2020

The African coelacanth genome provides insights into tetrapod evolution

scientific article

The Antarctic Weddell seal genome reveals evidence of selection on cardiovascular phenotype and lipid handling

scientific article published on 17 February 2022

The ESR1 gene is associated with risk for canine mammary tumours

scientific article

The Earth BioGenome Project 2020: Starting the clock

scientific article published on 25 January 2022

The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations

scientific article

The Shepherds' Tale: A Genome-Wide Study across 9 Dog Breeds Implicates Two Loci in the Regulation of Fructosamine Serum Concentration in Belgian Shepherds

scientific article published on 13 May 2015

The contribution of historical processes to contemporary extinction risk in placental mammals ⬇️

The dog and rat olfactory receptor repertoires

scientific article

The dog as a cancer model

article

The dog as a genetic model for immunoglobulin A (IgA) deficiency: identification of several breeds with low serum IgA concentrations

scientific article published on 27 May 2014

The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease

scientific article (publication date: December 2014)

The functional and evolutionary impacts of human-specific deletions in conserved elements ⬇️

The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels

scientific article published in September 2021

The genome of the green anole lizard and a comparative analysis with birds and mammals ⬇️

scientific article

The genomic basis of adaptive evolution in threespine sticklebacks

scientific article

The genomic signature of dog domestication reveals adaptation to a starch-rich diet

scientific article

The genomic substrate for adaptive radiation in African cichlid fish

scientific article

The mosaic structure of variation in the laboratory mouse genome

scientific article published in Nature

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

scientific article

Thoracolumbar meningeal fibrosis in pugs

scientific article published on 31 January 2020

Thorough investigation of a canine autoinflammatory disease (AID) confirms one main risk locus and suggests a modifier locus for amyloidosis.

scientific article

Three periods of regulatory innovation during vertebrate evolution ⬇️

scientific article

Three's company

scientific article published in Nature

Three-dimensional genome rewiring in loci with human accelerated regions ⬇️

scientific article published on 28 April 2023

Toll-like receptors revisited; a possible role for TLR1 in lupus nephritis

scientific article published on 29 September 2020

Transcriptomes from German shepherd dogs reveal differences in immune activity between atopic dermatitis affected and control skin

scientific article published on 18 June 2020

Two loci on chromosome 5 are associated with serum IgE levels in Labrador retrievers

scientific article

Unsupervised genome-wide recognition of local relationship patterns.

scientific article

Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development-Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus

scientific article

Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy

scientific article published on 16 May 2016

What animals can teach us about evolution, the human genome, and human disease

scientific article published on 14 February 2020

Whole-genome genotyping and resequencing reveal the association of a deletion in the complex interferon alpha gene cluster with hypothyroidism in dogs

scientific article published on 16 April 2020

Whole-genome resequencing reveals loci under selection during chicken domestication

scientific article

Whole-genome sequence assembly for mammalian genomes: Arachne 2.

scientific article

Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes

scientific article published on 09 June 2020

Why sequence all eukaryotes?

scientific article published on 01 January 2022

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

scientific article

ZBED6: The birth of a new transcription factor in the common ancestor of placental mammals

scientific article published on 17 August 2010

cgmisc: enhanced genome-wide association analyses and visualization

scientific article published on 6 August 2015

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