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List of works by Margarida F.B. Silva

Advances in methods for characterization of hepatic urea cycle enzymatic activity in HepaRG cells using UPLC-MS/MS.

scientific article

Characterization of plasma acylcarnitines in patients under valproate monotherapy using ESI-MS/MS.

scientific article published in November 2001

Complete beta-oxidation of valproate: cleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolase

scientific journal article

Differential effect of valproate and its Delta2- and Delta4-unsaturated metabolites, on the beta-oxidation rate of long-chain and medium-chain fatty acids.

scientific article published in September 2001

Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis

scientific article published in 2021

Inhibition of 3-methylcrotonyl-CoA carboxylase explains the increased excretion of 3-hydroxyisovaleric acid in valproate-treated patients

scientific article published on 22 December 2011

Mathematics in chemistry: indeterminate forms and their meaning

Mild form of methylmalonic aciduria misdiagnosed as propionic acidaemia during a ketotic crisis

scientific article published on 01 January 1991

New insights on the mechanisms of valproate-induced hyperammonemia: Inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA

scientific article published on 13 December 2010

Retrospective study of the medium-chain acyl-CoA dehydrogenase deficiency in Portugal.

scientific article

Studies on the extra-mitochondrial CoA-ester formation of valproic and Δ4-valproic acids

scientific article published on 23 January 2007

Synthesis and intramitochondrial levels of valproyl-coenzyme A metabolites.

scientific article

Tyrosinaemia type I with normal levels of plasma tyrosine

scientific article published on 01 January 1990

Valproate inhibits the mitochondrial pyruvate-driven oxidative phosphorylation in vitro

scientific article published on 01 July 1997

Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation

scientific article published on 10 July 2007

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