List of works by Olli H Laitinen

A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells

scientific article

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes

scientific article published on 18 November 2017

A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defence.

scientific article published on 9 September 2017

A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine

scientific article published on 27 August 2019

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates

scientific article published on 06 May 2020

A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo

scientific article

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.

scientific article published on 8 January 2018

A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.

scientific article published on 5 November 2014

Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection

scientific article published on 09 January 2020

Avidin Fusion Protein Strategies in Targeted Drug and Gene Delivery

article

Bacterial avidins are a widely distributed protein family in Actinobacteria, Proteobacteria and Bacteroidetes

Baculovirus capsid display: a novel tool for transduction imaging

scientific article published on November 2003

Baculovirus-mediated vascular endothelial growth factor-D(ΔNΔC) gene transfer induces angiogenesis in rabbit skeletal muscle

scientific article

Biodiversity intervention enhances immune regulation and health-associated commensal microbiota among daycare children

scientific article published on 14 October 2020

Brave new (strept)avidins in biotechnology

scientific article published on 12 April 2007

Characterization of poultry egg-white avidins and their potential as a tool in pretargeting cancer treatment.

scientific article published in May 2003

Chicken avidin-related protein 4/5 shows superior thermal stability when compared with avidin while retaining high affinity to biotin.

scientific article

Chicken avidin-related proteins show altered biotin-binding and physico-chemical properties as compared with avidin.

scientific article published on May 2002

Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus

scientific article published on 01 October 2019

Construction of a dual chain pseudotetrameric chicken avidin by combining two circularly permuted avidins.

scientific article

Construction of hevein (Hev b 6.02) with reduced allergenicity for immunotherapy of latex allergy by comutation of six amino acid residues on the conformational IgE epitopes.

scientific article published in February 2004

Correction: Saarinen, N.V.V., et al. Multiplexed High-Throughput Serological Assay for Human Enteroviruses. Microorganismis 2020, 8, 963

scientific article published on 17 September 2020

Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes

scientific article published on 5 February 2018

Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes

scientific article

Coxsackievirus B3 VLPs purified by ion exchange chromatography elicit strong immune responses in mice.

scientific article published on 28 January 2014

Coxsackievirus counters the host innate immune response by blocking type III interferon expression.

scientific article

Design and construction of highly stable, protease-resistant chimeric avidins.

scientific article published on 13 January 2005

Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity

scientific article published on 9 January 2017

Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants

scientific article

Diverse Environmental Microbiota as a Tool to Augment Biodiversity in Urban Landscaping Materials

scientific article published on 22 March 2019

Dual-affinity avidin molecules.

scientific article published in November 2005

Efficient preparation of shuffled DNA libraries through recombination (Gateway) cloning

scientific article published on December 2014

Efficient production of active chicken avidin using a bacterial signal peptide in Escherichia coli

scientific article published on December 2004

Engineering of chicken avidin: a progressive series of reduced charge mutants.

scientific article published on December 1998

Enhanced gene delivery by avidin-displaying baculovirus

scientific article published on February 2004

Enteroviral proteases: structure, host interactions and pathogenicity.

scientific article published on 4 May 2016

Genetically engineered avidins and streptavidins.

scientific article

Greening of Daycare Yards with Biodiverse Materials Affords Well-Being, Play and Environmental Relationships

scientific article published on 16 August 2019

Half-lives of PAHs and temporal microbiota changes in commonly used urban landscaping materials.

scientific article published on 19 March 2018

Host Cell Calpains Can Cleave Structural Proteins from the Enterovirus Polyprotein

scientific article published on 28 November 2019

Human enterovirus 71 strains in the background population and in hospital patients in Finland.

scientific article published on 21 December 2012

Modular vaccine platform based on the norovirus-like particle

scholarly article by Vili Lampinen et al published 19 January 2021 in Journal of Nanobiotechnology

Multiplexed High-Throughput Serological Assay for Human Enteroviruses

scientific article published on 26 June 2020

Mutation of a critical tryptophan to lysine in avidin or streptavidin may explain why sea urchin fibropellin adopts an avidin-like domain.

scientific article published in November 1999

Nature-derived microbiota exposure as a novel immunomodulatory approach.

scientific article

New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms.

scientific article published on 6 February 2018

Novel avidin-like protein from a root nodule symbiotic bacterium, Bradyrhizobium japonicum.

scientific article published on 28 January 2005

Novel vascular endothelial growth factor D variants with increased biological activity

scientific article published on 14 April 2009

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.

scientific article published on June 2017

Preparation of recombinant baculoviruses with the BVboost system

scientific article

Production of Hev b5 as a fluorescent biotin-binding tripartite fusion protein in insect cells.

scientific article

Rational design of an active avidin monomer.

scientific article published on 27 November 2002

Recombinant NeutraLite avidin: a non-glycosylated, acidic mutant of chicken avidin that exhibits high affinity for biotin and low non-specific binding properties

scientific article published on 01 February 2000

Short-term direct contact with soil and plant materials leads to an immediate increase in diversity of skin microbiota

scientific article published on 29 May 2018

Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine

scientific article published on 24 August 2020

Structure and characterization of a novel chicken biotin-binding protein A (BBP-A)

scientific article

Temporal variation in indoor transfer of dirt-associated environmental bacteria in agricultural and urban areas

scientific article published on 07 August 2019

Tetravalent single-chain avidin: from subunits to protein domains via circularly permuted avidins

scientific article published on December 2005

The abundance of health-associated bacteria is altered in PAH polluted soils-Implications for health in urban areas?

scientific article published on 16 November 2017

Transduction of vertebrate cells with recombinant baculovirus

scientific article

Urbanization Reduces Transfer of Diverse Environmental Microbiota Indoors.

scientific article

Yard vegetation is associated with gut microbiota composition

scientific article published on 15 January 2020