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List of works by Murray Clarke

Basic research: Killing the old: cell senescence in atherosclerosis.

scientific article published in December 2016

Bone marrow-derived smooth muscle-like cells are infrequent in advanced primary atherosclerotic plaques but promote atherosclerosis

scientific article published on 3 March 2011

Cause or Consequence

scientific article published on 26 November 2008

Cell Death, Damage-Associated Molecular Patterns, and Sterile Inflammation in Cardiovascular Disease

scientific article published on December 1, 2011

Cell death in the cardiovascular system

scientific article

Cell surface IL-1α trafficking is specifically inhibited by interferon-γ, and associates with the membrane via IL-1R2 and GPI anchors

scientific article published on 24 May 2020

Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration

scientific article published on 22 May 2008

Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis.

scientific article published on 14 May 2003

Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death

scientific article

Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program

scientific article published on 01 February 2000

Defining the role of vascular smooth muscle cell apoptosis in atherosclerosis.

scientific article published on 16 October 2006

IL-1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype.

scientific article published on 27 March 2019

Interleukin-1α Activity in Necrotic Endothelial Cells Is Controlled by Caspase-1 Cleavage of Interleukin-1 Receptor-2: IMPLICATIONS FOR ALLOGRAFT REJECTION.

scientific article

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

scientific journal article

Leukocyte telomere length is associated with high-risk plaques on virtual histology intravascular ultrasound and increased proinflammatory activity

scientific article published on 16 June 2011

Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans.

scientific article

Response to letter regarding article, "Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans".

scientific article published in March 2014

Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1α-Dependent Senescence-Associated Secretory Phenotype

scientific article

Signalling from dead cells drives inflammation and vessel remodelling

scientific article published on 28 January 2012

Smooth muscle cell apoptosis promotes vessel remodeling and repair via activation of cell migration, proliferation, and collagen synthesis.

scientific article published in November 2011

The CCR5 chemokine receptor mediates vasoconstriction and stimulates intimal hyperplasia in human vessels in vitro.

scientific article published on 09 December 2013

The emerging role of vascular smooth muscle cell apoptosis in atherosclerosis and plaque stability

scientific article published on 6 December 2006

Vascular Smooth Muscle Cell Senescence Promotes Atherosclerosis and Features of Plaque Vulnerability

scientific article published on 28 September 2015

Vascular smooth muscle cell apoptosis induces interleukin-1-directed inflammation: effects of hyperlipidemia-mediated inhibition of phagocytosis.

scientific article