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List of works by Rebecca C Fry

1163: Histopathologic chorioamnionitis and risk of neurodevelopmental impairment at age 10 years among extremely preterm infants ⬇️

scholarly article

13: Placental CpG methylation varies by extremely preterm birth (PTB) phenotype ⬇️

scholarly article

17β-estradiol and tamoxifen prevent gastric cancer by modulating leukocyte recruitment and oncogenic pathways in Helicobacter pylori-infected INS-GAS male mice

scientific article

719: Maternal genotype varies by delivery gestational age ⬇️

scholarly article

A Systems Toxicology-based Approach Reveals Biological Pathways Dysregulated by Prenatal Arsenic Exposure.

scientific article published on January 2016

A role for microRNAs in the epigenetic control of sexually dimorphic gene expression in the human placenta

scientific article published on 09 September 2020

A toxicogenomic comparison of primary and photochemically altered air pollutant mixtures

scientific article published on 14 July 2011

Acetaminophen modulates the expression of steroidogenesis-associated genes and estradiol levels in human placental JEG-3 cells

scientific article published on 24 October 2020

Acetaminophen use during pregnancy and DNA methylation in the placenta of the extremely low gestational age newborn (ELGAN) cohort

scientific article published on 01 April 2019

Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers

scientific article

Advancing Dose-Response Assessment Methods for Environmental Regulatory Impact Analysis: A Bayesian Belief Network Approach Applied to Inorganic Arsenic.

scientific article published on 20 April 2016

Air toxics and epigenetic effects: ozone altered microRNAs in the sputum of human subjects

scientific article

Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile.

scientific article published on January 2012

An assessment of serum-dependent impacts on intracellular accumulation and genomic response of per- and polyfluoroalkyl substances in a placental trophoblast model ⬇️

scientific article published on 13 August 2020

Analysis of bladder cancer tumor CpG methylation and gene expression within The Cancer Genome Atlas identifies GRIA1 as a prognostic biomarker for basal-like bladder cancer

scientific article published on September 2017

Analysis of maternal polymorphisms in arsenic (+3 oxidation state)-methyltransferase AS3MT and fetal sex in relation to arsenic metabolism and infant birth outcomes: Implications for risk analysis

scientific article published on 26 February 2016

Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae.

scientific article

Arsenic and the epigenome: interindividual differences in arsenic metabolism related to distinct patterns of DNA methylation

scientific article published on 11 January 2013

Arsenic in North Carolina: public health implications

scientific article published on 10 September 2011

Arsenic-Associated Changes to the Epigenome: What Are the Functional Consequences?

scientific article

Assessing Positive Child Health among Individuals Born Extremely Preterm

article

Association Between Variants in Arsenic (+3 Oxidation State) Methyltranserase (AS3MT) and Urinary Metabolites of Inorganic Arsenic: Role of Exposure Level.

scientific article published on 30 June 2016

Association between arsenic, cadmium, manganese, and lead levels in private wells and birth defects prevalence in North Carolina: a semi-ecologic study

scientific article

Associations between arsenic species in exfoliated urothelial cells and prevalence of diabetes among residents of Chihuahua, Mexico

scientific article

Associations between placental CpG methylation of metastable epialleles and childhood body mass index across ages one, two and ten in the Extremely Low Gestational Age Newborns (ELGAN) cohort

scientific article published on 02 July 2019

Benchmark Dose Modeling Estimates of the Concentrations of Inorganic Arsenic That Induce Changes to the Neonatal Transcriptome, Proteome, and Epigenome in a Pregnancy Cohort.

scientific article

CUE: CpG impUtation ensemble for DNA methylation levels across the human methylation450 (HM450) and EPIC (HM850) BeadChip platforms

scientific article published on 04 October 2020

Cadmium body burden and increased blood pressure in middle-aged American Indians: the Strong Heart Study

scientific article published on 15 September 2016

Cadmium disrupts signaling of the hypoxia-inducible (HIF) and transforming growth factor (TGF-β) pathways in placental JEG-3 trophoblast cells via reactive oxygen species.

scientific article published on 2 February 2018

Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs.

scientific article published on 28 October 2013

Cadmium inhibits placental trophoblast cell migration via miRNA regulation of the transforming growth factor beta (TGF-β) pathway.

scientific article published on 31 July 2017

Cadmium levels in a North Carolina cohort: Identifying risk factors for elevated levels during pregnancy

scientific article

Catecholamine release mediates pressor effects of adrenomedullin-(15-22) in the rat

scientific article published on 01 December 1996

Cellular interactions and biological responses to titanium dioxide nanoparticles in HepG2 and BEAS-2B cells: role of cell culture media ⬇️

journal article published in 2014

Characterization of a strong dominant phytochrome A mutation unique to phytochrome A signal propagation.

scientific article published in September 2002

Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi.

scientific article

Chronic Exposure to Arsenic and Markers of Cardiometabolic Risk: A Cross-Sectional Study in Chihuahua, Mexico

scientific article

Chronic early childhood exposure to arsenic is associated with a TNF-mediated proteomic signaling response

scientific article published on 8 April 2017

Circulating miRNAs Associated with Arsenic Exposure

scientific article published on 04 December 2018

Comparative genomic analyses identify common molecular pathways modulated upon exposure to low doses of arsenic and cadmium

scientific article

Comparative modeling and analysis of microfluidic and conventional DNA microarrays.

scientific article published on 8 November 2005

Correction to: Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in Mexico

scientific article published on 01 September 2019

Cytomegalovirus seroprevalence, recurrence, and antibody levels: Associations with cadmium and lead exposures in the general United States population

scientific article published on 05 June 2020

DNA damage and stress transcripts in Saccharomyces cerevisiae mutant sgs1

scientific article published on 01 July 2003

DNA methylation in nasal epithelial cells from smokers: identification of ULBP3-related effects

scientific article published on 05 July 2013

DNA methylation modifies urine biomarker levels in 1,6-hexamethylene diisocyanate exposed workers: a pilot study

journal article published in 2014

Developing novel in vitro methods for the risk assessment of developmental and placental toxicants in the environment

scientific article published on 22 June 2019

Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research

scientific article published in 2022

Developmental Windows of Susceptibility to Inorganic Arsenic: A Survey of Current Toxicologic and Epidemiologic Data.

scientific article published on 16 September 2016

Diarrhea as a cause of mortality in a mouse model of infectious colitis

scientific article published on 04 August 2008

Differential metabolism of inorganic arsenic in mice from genetically diverse Collaborative Cross strains

scientific article published on 06 September 2019

Discrimination exposure and DNA methylation of stress-related genes in Latina mothers.

scientific article published on 16 August 2018

Disinfection Byproducts Bind Human Estrogen Receptor-α

scientific article published on 20 March 2019

Disruption of microRNA expression in human airway cells by diesel exhaust particles is linked to tumorigenesis-associated pathways

scientific article

Dose and temporal effects on gene expression profiles of urothelial cells from rats exposed to diuron.

scientific article published on 23 August 2014

E-cigarette use results in suppression of immune and inflammatory-response genes in nasal epithelial cells similar to cigarette smoke

scientific article

Early life antecedents of positive child health among 10-year-old children born extremely preterm

scientific article published on 20 April 2019

Effect of secondary organic aerosol from isoprene-derived hydroxyhydroperoxides on the expression of oxidative stress response genes in human bronchial epithelial cells.

scientific article published on 2 January 2018

Effects of Preconception and in Utero Inorganic Arsenic Exposure on the Metabolic Phenotype of Genetically Diverse Collaborative Cross Mice

scientific article published on 08 July 2019

Effects of prenatal exposure to endocrine disruptors and toxic metals on the fetal epigenome

scientific article published on 17 February 2017

Elevated Cardiometabolic Risk by Chronic Inorganic Arsenic Exposure in Chihuahua, Mexico. ⬇️

scholarly article

Environmental Influences on the Epigenome: Exposure-Associated DNA Methylation in Human Populations

scientific article published on 12 January 2018

Environmental contaminants and microRNA regulation: Transcription factors as regulators of toxicant-altered microRNA expression

scientific article published on 09 June 2016

Epigenetic Regulation of the Nitric Oxide Pathway, 17-α Hydroxyprogesterone Caproate, and Recurrent Preterm Birth.

scientific article

Epigenetic changes in individuals with arsenicosis

scientific article

Epigenetic changes induced by air toxics: formaldehyde exposure alters miRNA expression profiles in human lung cells

scientific article

Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway

scientific article published on 28 October 2015

Epigenome-wide DNA methylation in placentas from preterm infants: association with maternal socioeconomic status

scientific article published on 21 May 2019

Erratum: Acetaminophen use during pregnancy and DNA methylation in the placenta of the extremely low gestational age newborn (ELGAN) cohort

scientific article published on 01 January 2020

Evaluation of plasma arsenicals as potential biomarkers of exposure to inorganic arsenic

scientific article published on 06 February 2019

Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm

scientific article published on 11 December 2020

Fetal-sex dependent genomic responses in the circulating lymphocytes of arsenic-exposed pregnant women in New Hampshire.

scientific article published on 6 August 2017

Formaldehyde and epigenetic alterations: microRNA changes in the nasal epithelium of nonhuman primates.

scientific article published on 15 January 2013

Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment

scientific article

Formaldehyde-associated changes in microRNAs: tissue and temporal specificity in the rat nose, white blood cells, and bone marrow

scientific article published on 04 December 2013

From the Field to the Laboratory: Air Pollutant-Induced Genomic Effects in Lung Cells

scientific article

Gene Expression Profiling in Human Lung Cells Exposed to Isoprene-Derived Secondary Organic Aerosol.

scientific article

Genetic and epigenetic mechanisms underlying arsenic-associated diabetes mellitus: a perspective of the current evidence

scientific article published on 4 May 2017

Genetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus-infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune func

scientific article published on 19 February 2008

Genome-wide responses to DNA-damaging agents.

scientific article

Genomic biomarkers of prenatal intrauterine inflammation in umbilical cord tissue predict later life neurological outcomes

journal article published in 2017

Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance.

scientific article

Genomic predictors of interindividual differences in response to DNA damaging agents

scientific article published on 19 September 2008

Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens.

scientific article published on January 2010

Haem-regulated eIF2alpha kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency.

scientific article published on 28 July 2008

Hepatic temporal gene expression profiling in Helicobacter hepaticus-infected A/JCr mice

scientific article published on 01 November 2004

Hepatocellular carcinoma associated with liver-gender disruption in male mice.

scientific article

High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure

scientific article

Histologic chorioamnionitis and risk of neurodevelopmental impairment at age 10 years among extremely preterm infants born less than 28 weeks of gestation

scientific article published on 06 May 2020

Identification of endocrine active disinfection by-products (DBPs) that bind to the androgen receptor.

scientific article

Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer

scientific article published on 3 June 2015

Identification of novel human damage response proteins targeted through yeast orthology.

scientific article

Identifying risk factors for levels of per- and polyfluoroalkyl substances (PFAS) in the placenta in a high-risk pregnancy cohort in North Carolina

scientific article published on 29 May 2020

Identifying the Transcriptional Response of Cancer and Inflammation-Related Genes in Lung Cells in Relation to Ambient Air Chemical Mixtures in Houston, Texas

scientific article published on 16 October 2020

Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury

scientific article

In vitro exposure to isoprene-derived secondary organic aerosol by direct deposition and its effects on <i>COX-2</i> and <i>IL-8</i> gene expression

scholarly article

Incorporating ToxCast and Tox21 datasets to rank biological activity of chemicals at Superfund sites in North Carolina.

scientific article

Incorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: strategies and challenges

scientific article

Increased R2* in the Caudate Nucleus of Asymptomatic Welders

scientific article published on 14 January 2016

Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways

scientific article published on 3 October 2012

Influenza enhances caspase-1 in bronchial epithelial cells from asthmatic volunteers and is associated with pathogenesis.

scientific article

Inorganic arsenic and its methylated metabolites as endocrine disruptors in the placenta: Mechanisms underpinning glucocorticoid receptor (GR) pathway perturbations

scientific article published on 28 October 2020

Inorganic arsenic as an endocrine disruptor: modulation of the glucocorticoid receptor pathway in placental cells via CpG methylation

journal article published in 2019

Integrative exposomic, transcriptomic, epigenomic analyses of human placental samples links understudied chemicals to preeclampsia

scientific article published in 2022

Investigating Epigenetic Effects of Prenatal Exposure to Toxic Metals in Newborns: Challenges and Benefits

scientific article

Investigating the Role of Fetal Gene Expression in Preterm Birth.

scientific article published on 27 September 2016

Isoprene-Derived Secondary Organic Aerosol Induces the Expression of MicroRNAs Associated with Inflammatory/Oxidative Stress Response in Lung Cells

scientific article published on 13 December 2019

Isoprene-Derived Secondary Organic Aerosol Induces the Expression of Oxidative Stress Response Genes in Human Lung Cells

article

Long-Term Health Effects and Underlying Biological Mechanisms of Developmental Exposure to Arsenic

scientific article published on 6 February 2018

Long-term health consequences of prenatal arsenic exposure: links to the genome and the epigenome

scientific article

Longitudinal T1 relaxation rate (R1) captures changes in short-term Mn exposure in welders

scientific article published on 24 August 2016

Maternal arsenic exposure, arsenic methylation efficiency, and birth outcomes in the Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort in Mexico

scientific article

Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort

scientific article published on 15 February 2016

Maternal cadmium levels during pregnancy associated with lower birth weight in infants in a North Carolina cohort

scientific article

Maternal cadmium, iron and zinc levels, DNA methylation and birth weight

scientific article

Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in Mexico.

scientific article published in August 2018

Mechanisms Underlying Latent Disease Risk Associated with Early-Life Arsenic Exposure: Current Research Trends and Scientific Gaps.

scientific article published on 26 June 2015

Metabolomic characteristics of arsenic-associated diabetes in a prospective cohort in Chihuahua, Mexico

scientific article

Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure.

scientific article published on 16 February 2016

Methylomic analysis of salivary DNA in childhood ADHD identifies altered DNA methylation in VIPR2.

scientific article

Microorganisms in the Placenta: Links to Early-Life Inflammation and Neurodevelopment in Children

scientific article published on 01 May 2019

Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes.

scientific article published on 14 December 2017

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses

scientific article published on 11 June 2007

Neonatal Metabolomic Profiles Related to Prenatal Arsenic Exposure

scientific article

Neurocognitive and social-communicative function of children born very preterm at 10 years of age: Associations with microorganisms recovered from the placenta parenchyma

scientific article published on 17 October 2019

Nonresponse to 17-alpha hydroxyprogesterone caproate for recurrent spontaneous preterm birth prevention: clinical prediction and generation of a risk scoring system

scientific article published on 11 July 2016

One-carbon metabolism nutrient intake and the association between body mass index and urinary arsenic metabolites in adults in the Chihuahua cohort

scientific article published on 13 December 2018

Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program

scientific article published on 17 February 2020

Perfluoroalkyl Substances (PFAS) and Their Effects on the Placenta, Pregnancy, and Child Development: a Potential Mechanistic Role for Placental Peroxisome Proliferator-Activated Receptors (PPARs)

scientific article published on 18 August 2020

Placental Cadmium Levels Are Associated with Increased Preeclampsia Risk

scientific article

Placental CpG Methylation of Inflammation, Angiogenic, and Neurotrophic Genes and Retinopathy of Prematurity

scientific article published on 01 July 2019

Placental CpG methylation of HPA-axis genes is associated with cognitive impairment at age 10 among children born extremely preterm

journal article published in 2018

Placental CpG methylation of infants born extremely preterm predicts cognitive impairment later in life.

journal article published in 2018

Placental Genomic and Epigenomic Signatures Associated with Infant Birth Weight Highlight Mechanisms Involved in Collagen and Growth Factor Signaling

scientific article published on 25 July 2020

Placental genomics mediates genetic associations with complex health traits and disease

scientific article published on 04 February 2022

Placental microRNAs: Responders to environmental chemicals and mediators of pathophysiology of the human placenta

scientific article published on 15 August 2020

Placental programming, perinatal inflammation, and neurodevelopment impairment among those born extremely preterm

scientific article published on 12 November 2020

Predictors of toxic metal exposures among US women of reproductive age

scientific article published on 24 June 2019

Prenatal Exposure to Cadmium and Cotinine and CpG island DNA methylation in Mother-Infant Pairs.

scientific article

Prenatal arsenic exposure and shifts in the newborn proteome: interindividual differences in tumor necrosis factor (TNF)-responsive signaling

scientific article

Prenatal arsenic exposure and the epigenome: altered microRNAs associated with innate and adaptive immune signaling in newborn cord blood.

scientific article

Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes

scientific article

Prenatal exposure to arsenic and cadmium impacts infectious disease-related genes within the glucocorticoid receptor signal transduction pathway

journal article published in 2014

Proadrenomedullin NH2-terminal peptide (PAMP)(12-20) has vasodepressor activity in the rat and cat

scientific article published on 01 January 1997

Quality Improvement in Perinatal Medicine and Translation of Preterm Birth Research Findings into Clinical Care

scientific article published on 23 February 2018

RNA steady-state defects in myotonic dystrophy are linked to nuclear exclusion of SHARP.

scientific article

RNA-Sequencing of Umbilical Cord Blood to Investigate Spontaneous Preterm Birth: A Pilot Study

scientific article published on 01 January 2019

Rat liver sinusoidal endothelial cells survive without exogenous VEGF in 3D perfused co-cultures with hepatocytes.

scientific article published on 10 April 2007

Review of the environmental prenatal exposome and its relationship to maternal and fetal health

scientific article published on 22 February 2020

Roadmap for investigating epigenome deregulation and environmental origins of cancer

scientific article published on 13 September 2017

Serum lead, mercury, manganese, and copper and DNA methylation age among adults in Detroit, Michigan

scientific article published in 2022

Sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ cells and on transcriptomic profiles and diabetic phenotype of offspring

scientific article published on 03 November 2020

Sexual epigenetic dimorphism in the human placenta: implications for susceptibility during the prenatal period.

scientific article

Standardizing global gene expression analysis between laboratories and across platforms.

scientific article

Systems biology and birth defects prevention: blockade of the glucocorticoid receptor prevents arsenic-induced birth defects

scientific article published on 3 January 2013

T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX.

scientific article published on 28 September 2015

T1 Relaxation Rate (R1) Indicates Nonlinear Mn Accumulation in Brain Tissue of Welders With Low-Level Exposure

scientific article

Targeted Multiplex Gene Expression Profiling to Measure High-Fat Diet and Metformin Effects on Fetal Gene Expression in a Mouse Model

article

The Biomarkers of Exposure to Arsenic (BEAR) Pregnancy Cohort in Mexico: Maternal Arsenic Methylation Linked to Poorer Birth Outcomes ⬇️

scholarly article

The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA.

scientific article

The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel.

scientific article

The aryl hydrocarbon receptor pathway: a key component of the microRNA-mediated AML signalisome

scientific article

The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner

scientific article (publication date: 2011)

The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic

scientific article

The placenta epigenome-brain axis: placental epigenomic and transcriptomic responses that preprogram cognitive impairment

journal article published in 2022

Titanium dioxide nanoparticles activate the ATM-Chk2 DNA damage response in human dermal fibroblasts ⬇️

scientific article published on August 23, 2012

Towards prenatal biomonitoring in North Carolina: assessing arsenic, cadmium, mercury, and lead levels in pregnant women

scientific article (publication date: 2012)

Toxic metal levels in children residing in a smelting craft village in Vietnam: a pilot biomonitoring study

scientific article published on 04 February 2014

Toxic metals in amniotic fluid and altered gene expression in cell-free fetal RNA.

scientific article published on 7 November 2017

Toxicological responses of environmental mixtures: Environmental metal mixtures display synergistic induction of metal-responsive and oxidative stress genes in placental cells

scientific article

Transcriptional Modulation of the ERK1/2 MAPK and NF-κB Pathways in Human Urothelial Cells After Trivalent Arsenical Exposure: Implications for Urinary Bladder Cancer ⬇️

scientific article published on August 21, 2012

Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates.

scientific article

Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.

scientific article

Two distinct trophectoderm lineage stem cells from human pluripotent stem cells

scientific article published on 01 January 2021

Ubiquitous identification of inorganic arsenic in a cohort of second trimester amniotic fluid in women with preterm and term births

scientific article published on 23 May 2019

Understanding positive child health

scientific article published on 14 September 2019

Unraveling 50-Year-Old Clues Linking Neurodegeneration and Cancer to Cycad Toxins: Are microRNAs Common Mediators?

scientific article

Urinary trace metals, maternal circulating angiogenic biomarkers, and preeclampsia: a single-contaminant and mixture-based approach

scientific article published on 12 July 2019

Use of Genome Editing Tools in Environmental Health Research

scientific article published on 02 March 2019

Validation of a Metallomics Analysis of Placenta Tissue by Inductively-Coupled Plasma Mass Spectrometry.

scientific article

Western Pacific ALS-PDC: a prototypical neurodegenerative disorder linked to DNA damage and aberrant proteogenesis?

scientific article published on 21 December 2012

miRNAs as common regulators of the transforming growth factor (TGF)-β pathway in the preeclamptic placenta and cadmium-treated trophoblasts: Links between the environment, the epigenome and preeclampsia

scientific article

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