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List of works by Erika Cecchin

A Clinical-Genetic Score to Identify Surgically Resected Colorectal Cancer Patients Benefiting From an Adjuvant Fluoropyrimidine-Based Therapy

scientific article published on 04 October 2018

A New Genetic Risk Score to Predict the Outcome of Locally Advanced or Metastatic Breast Cancer Patients Treated With First-Line Exemestane: Results From a Prospective Study

scientific article published on 24 November 2018

A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long Term Side Effects after Finasteride Discontinuation

article

A novel UGT1 marker associated with better tolerance against irinotecan-induced severe neutropenia in metastatic colorectal cancer patients

scientific article published on 17 March 2015

ABCC5 and ABCG1 polymorphisms predict irinotecan-induced severe toxicity in metastatic colorectal cancer patients.

scientific article published on 8 September 2015

Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia.

scientific article published on 23 December 2016

Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients.

scientific article published on 13 April 2018

Association of theHLA-G3′UTR polymorphisms with colorectal cancer in Italy: a first insight

scientific article (publication date: 21 December 2015)

Azathioprine Biotransformation in Young Patients with Inflammatory Bowel Disease: Contribution of Glutathione-S Transferase M1 and A1 Variants.

scientific article published on 4 April 2019

BNC2 is a putative tumor suppressor gene in high-grade serous ovarian carcinoma and impacts cell survival after oxidative stress

scientific article published on 22 September 2016

BNC2 is a putative tumor suppressor gene in high-grade serous ovarian carcinoma and impacts cell survival after oxidative stress

scientific article published on 22 December 2016

CDK4/6 Inhibitors in Breast Cancer Treatment: Potential Interactions with Drug, Gene, and Pathophysiological Conditions

scientific article published on 01 September 2020

CORRIGENDUM: Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium

scientific article published on 01 July 2017

Carboxylesterase isoform 2 mRNA expression in peripheral blood mononuclear cells is a predictive marker of the irinotecan to SN38 activation step in colorectal cancer patients.

scientific article

Circulating-Free DNA Analysis in Hepatocellular Carcinoma: A Promising Strategy to Improve Patients' Management and Therapy Outcomes ⬇️

scientific article published on 05 November 2019

Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy

scientific article published on 22 April 2022

Clinical validity of a DPYD-based pharmacogenetic test to predict severe toxicity to fluoropyrimidines

scientific article published on 23 June 2015

Clonal Evolution of TP53 c.375+1G>A Mutation in Pre- and Post- Neo-Adjuvant Chemotherapy (NACT) Tumor Samples in High-Grade Serous Ovarian Cancer (HGSOC)

scientific article published on 01 October 2019

Cost Evaluation of Irinotecan-Related Toxicities Associated With the UGT1A1*28 Patient Genotype.

scientific article published on 11 January 2017

Decision criteria for rational selection of homogeneous genotyping platforms for pharmacogenomics testing in clinical diagnostics.

scientific article published on April 2010

Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study.

scientific article published on 8 July 2016

Educating the Next Generation of Pharmacogenomics Experts: Global Educational Needs and Concepts

scientific article published on 25 June 2019

Estimating the Effectiveness of DPYD Genotyping in Italian Individuals Suffering from Cancer Based on the Cost of Chemotherapy-Induced Toxicity

scientific article published on 30 May 2019

FARMAPRICE: A Pharmacogenetic Clinical Decision Support System for Precise and Cost-Effective Therapy.

scientific article published on 4 April 2019

Focal Recurrent Copy Number Alterations Characterize Disease Relapse in High Grade Serous Ovarian Cancer Patients with Good Clinical Prognosis: A Pilot Study

scientific article published on 05 September 2019

Genetic Variants of the TERT Gene, Telomere Length, and Circulating TERT as Prognostic Markers in Rectal Cancer Patients

scientific article published on 25 October 2020

Genetic biomarkers for hepatocellular cancer risk in a caucasian population.

scientific article published on September 2017

Genetic diversity of the KIR/HLA system and outcome of patients with metastatic colorectal cancer treated with chemotherapy.

scientific article published on 31 January 2014

Genetic markers of the host to predict the efficacy of colorectal cancer targeted therapy

scientific article published on 12 July 2019

Germline variability and tumor expression level of ribosomal protein gene RPL28 are associated with survival of metastatic colorectal cancer patients

scientific article published on 10 September 2019

HLA-G 3'UTR Polymorphisms Impact the Prognosis of Stage II-III CRC Patients in Fluoropyrimidine-Based Treatment.

scientific article published on 3 December 2015

HLA-G 3'UTR Polymorphisms Predict Drug-Induced G3-4 Toxicity Related to Folinic Acid/5-Fluorouracil/Oxaliplatin (FOLFOX4) Chemotherapy in Non-Metastatic Colorectal Cancer.

scientific article

Host genetic profiling to increase drug safety in colorectal cancer from discovery to implementation

scientific article published on 10 July 2018

Identification of Novel Somatic TP53 Mutations in Patients with High-Grade Serous Ovarian Cancer (HGSOC) Using Next-Generation Sequencing (NGS).

scientific article published on 18 May 2018

Impact of DNA repair gene polymorphisms on the risk of biochemical recurrence after radiotherapy and overall survival in prostate cancer

scientific article

Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium.

scientific article published on 27 December 2016

Improved Progression-Free Survival in Irinotecan-Treated Metastatic Colorectal Cancer Patients Carrying the HNF1A Coding Variant p.I27L.

scientific article published on 10 October 2017

Improving decision making on DPYD and UGT1A1*28 patients' profiling with an innovative reimbursement strategy.

scientific article published on 14 February 2018

Lack of association of CYP1 B1*3 polymorphism and ovarian cancer in a Caucasian population.

scientific article published in April 2004

MTHFR polymorphisms in gastric cancer and in first-degree relatives of patients with gastric cancer.

scientific article

MTHFR-1298 A>C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin

scientific article published on 21 October 2014

New Challenges in Tumor Mutation Heterogeneity in Advanced Ovarian Cancer by a Targeted Next-Generation Sequencing (NGS) Approach

scientific article published on 14 June 2019

Nuclear receptors and drug metabolism for the personalization of cancer therapy

scientific article

Pharmacogenetic score predicts overall survival, progression-free survival and platinum sensitivity in ovarian cancer

scientific article published on 08 September 2020

Pharmacogenetics Biomarkers and Their Specific Role in Neoadjuvant Chemoradiotherapy Treatments: An Exploratory Study on Rectal Cancer Patients.

scientific article published on 05 September 2016

Pharmacogenetics and stomach cancer: an update.

scientific article published on May 2007

Pharmacogenetics of ABC and SLC transporters in metastatic colorectal cancer patients receiving first-line FOLFIRI treatment.

scientific article published in October 2013

Pharmacogenetics of irinotecan.

scientific article

Pharmacogenetics of stomach cancer.

scientific article

Pharmacogenetics of the nuclear hormone receptors: the missing link between environment and drug effects?

scientific article published on December 2013

Pharmacogenetics of the systemic treatment in advanced hepatocellular carcinoma

scientific article published on 01 August 2019

Pharmacogenomics and Personalized Medicine

scientific article published on 22 June 2020

Pharmacogenomics and stomach cancer.

scientific article published in September 2004

Pharmacogenomics of Targeted Agents for Personalization of Colorectal Cancer Treatment

scientific article published on 14 July 2017

Pharmacogenomics of intrinsic and acquired pharmacoresistance in colorectal cancer: Toward targeted personalized therapy.

scientific article published on 22 May 2015

Pharmacology of epidermal growth factor inhibitors.

scientific article published in January 2007

Predictive response biomarkers in rectal cancer neoadjuvant treatment.

scientific article published on January 2014

Predictive role of microRNA-related genetic polymorphisms in the pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

scientific article published on 26 February 2016

Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

scientific article

Pregnane X receptor, constitutive androstane receptor and hepatocyte nuclear factors as emerging players in cancer precision medicine.

scientific article

Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens.

scientific article published on 05 February 2013

SNCA 3'UTR genetic variants in patients with Parkinson's disease and REM sleep behavior disorder

scientific article published on 13 April 2017

Standard fluoropyrimidine dosages in chemoradiation therapy result in an increased risk of severe toxicity in DPYD variant allele carriers

article

The Role of UGT1A1*28 Polymorphism in the Pharmacodynamics and Pharmacokinetics of Irinotecan in Patients With Metastatic Colorectal Cancer

scientific article published on 01 July 2006

The genotype for DPYD risk variants in colorectal cancer patients and the related toxicity management costs in clinical practice

article

Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy

scientific article published on 06 April 2010

UGT1A polymorphisms as genetic biomarkers for hepatocellular carcinoma risk in Caucasian population

scientific article published on 12 March 2017

UGT1A1*28 polymorphism in ovarian cancer patients.

scientific article published in August 2004

Ubiquitous Pharmacogenomics (U-PGx): The time for implementation is now. An Horizon2020 program to drive pharmacogenomics into clinical practice

scientific article published on 02 January 2017

Uridine diphosphoglucuronosyl transferase and methylenetetrahydrofolate reductase polymorphisms as genomic predictors of toxicity and response to irinotecan-, antifolate- and fluoropyrimidine-based chemotherapy.

scientific article

miRNA Pharmacogenomics: The New Frontier for Personalized Medicine in Cancer? ⬇️

scientific article published on November 1, 2012

rs4143815-PDL1, a New Potential Immunogenetic Biomarker of Biochemical Recurrence in Locally Advanced Prostate Cancer after Radiotherapy.

scientific article published on 27 April 2019

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