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List of works by Maria Cristina Manara

4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a promising new candidate for chemotherapeutic treatment of osteosarcoma patients.

scientific article published on September 2005

A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy

scientific article published on 29 June 2018

An aza-macrocycle containing maltolic side-arms (maltonis) as potential drug against human pediatric sarcomas.

scientific article

Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.

scientific article

Biological indicators of prognosis in Ewing's sarcoma: an emerging role for lectin galactoside-binding soluble 3 binding protein (LGALS3BP).

scientific article

C-kit receptor expression in Ewing's sarcoma: lack of prognostic value but therapeutic targeting opportunities in appropriate conditions.

scientific article published in May 2003

CD99 acts as an oncosuppressor in osteosarcoma

scientific article

CD99 drives terminal differentiation of osteosarcoma cells by acting as a spatial regulator of ERK 1/2.

scientific article

CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin

scientific article published on 11 December 2014

Caveolin-1 reduces osteosarcoma metastases by inhibiting c-Src activity and met signaling.

scientific article published on August 2007

Characterization of human mesenchymal stem cells from ewing sarcoma patients. Pathogenetic implications

scientific article published on 3 February 2014

Contribution of MEK/MAPK and PI3-K signaling pathway to the malignant behavior of Ewing's sarcoma cells: therapeutic prospects

scientific article published on January 2004

Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells

scientific article published on 20 January 2014

Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells.

scientific article published on September 2002

Expression of insulin-like growth factor system components in Ewing's sarcoma and their association with survival.

scientific article

Generation of human single-chain antibody to the CD99 cell surface determinant specifically recognizing Ewing's sarcoma tumor cells.

scientific article

Identification of candidate genes involved in the reversal of malignant phenotype of osteosarcoma cells transfected with the liver/bone/kidney alkaline phosphatase gene.

scientific article published on April 2004

Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma.

scientific article

In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type

scientific article (publication date: 23 June 2005)

Insulin-like growth factor binding protein 3 as an anticancer molecule in Ewing's sarcoma.

scientific article published on September 2006

Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma

scientific article published on 13 December 2021

Metformin as an adjuvant drug against pediatric sarcomas: hypoxia limits therapeutic effects of the drug

scientific article (publication date: 2013)

Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators.

scientific article

Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome

scientific article published on 23 March 2009

Oxidative Stress in Autistic Children Alters Erythrocyte Shape in the Absence of Quantitative Protein Alterations and of Loss of Membrane Phospholipid Asymmetry

scientific article published on 11 November 2018

Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma

scientific article published on 17 February 2021

Targeting CD99 in association with doxorubicin: an effective combined treatment for Ewing's sarcoma

scientific article published on 2 December 2005

Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy.

scientific article published in January 2011

The expression of ccn3(nov) gene in musculoskeletal tumors

scientific article published on March 2002

Trabectedin efficacy in Ewing sarcoma is greatly increased by combination with anti-IGF signaling agents.

scientific article

miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy

scientific article published on April 2012

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