Search filters

List of works by Kang Sim

A 24-month prospective outcome study of first-episode schizophrenia and schizoaffective disorder within an early psychosis intervention program.

scientific article published in September 2007

A bibliometric study of scientific research conducted on second-generation antipsychotic drugs in Singapore

scientific article

A comparison of clinical characteristics of older adults treated with antidepressants in general and psychiatric hospitals in Asia.

scientific article published on 21 April 2017

A comparison of the reliability and validity of SF-6D, EQ-5D and HUI3 utility measures in patients with schizophrenia and patients with depression in Singapore

scientific article published on 01 March 2019

ARVCFGenetic Influences on Neurocognitive and Neuroanatomical Intermediate Phenotypes in Chinese Patients With Schizophrenia

scientific article published on October 18, 2011

Actigraphy studies and clinical and biobehavioural correlates in schizophrenia: a systematic review

scientific article published on 19 March 2019

Adapted cognitive-behavioral therapy for religious individuals with mental disorder: a systematic review.

scientific article published on 04 January 2014

Adjunctive antidepressant prescriptions for hospitalized patients with schizophrenia in Asia (2001-2009).

scientific article published on 29 August 2012

Adjunctive metformin for antipsychotic-induced dyslipidemia: a meta-analysis of randomized, double-blind, placebo-controlled trials

scientific article published on 23 April 2020

Adjunctive mood stabilizer and benzodiazepine use in older Asian patients with schizophrenia, 2001-2009.

scientific article published on 30 January 2012

Adjunctive mood stabilizer treatment for hospitalized schizophrenia patients: Asia psychotropic prescription study (2001-2008).

scientific article published on 18 April 2011

Adjunctive ondansetron for schizophrenia: A systematic review and meta-analysis of randomized controlled trials

scientific article published on 05 March 2019

Adoption and correlates of Postgraduate Hospital Educational Environment Measure (PHEEM) in the evaluation of learning environments - A systematic review.

scientific article published on 26 August 2016

Adoption and correlates of the Dundee Ready Educational Environment Measure (DREEM) in the evaluation of undergraduate learning environments - a systematic review

scientific article published on 23 January 2018

Altered intra- and inter-hemispheric functional dysconnectivity in schizophrenia

scientific article published on 01 October 2019

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Antipsychotic drug prescription for schizophrenia in East Asia: rationale for change.

scientific article published in February 2004

Antipsychotic polypharmacy in inpatients with schizophrenia in Asia (2001-2009).

scientific article published on 11 October 2011

Antipsychotic treatment in older schizophrenia patients with extrapyramidal side effects in Asia (2001 - 2009).

scientific article

Arcuate fasciculus abnormalities and their relationship with psychotic symptoms in schizophrenia

scientific article

Asymmetry of lexico-semantic processing in schizophrenia changes with disease progression.

scientific article published on 03 December 2011

Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group

scientific article published on 18 May 2020

Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders : Evidence through univariate and multivariate mega-analysis including 6420 participants from the ENIGMA MDD working group

scientific article published on 28 May 2020

CACNA1C genomewide supported psychosis genetic variation affects cortical brain white matter integrity in Chinese patients with schizophrenia

scientific article published in November 2014

Case formulation in psychotherapy: revitalizing its usefulness as a clinical tool.

scientific article published in July 2005

Clarifying pathways to poor psychological health: The mediating role of psychosocial factors in the relationship between general psychopathology and quality of life impairment in patients diagnosed with schizophrenia.

scientific article published on 23 January 2019

Clinical Use of Mood Stabilizers With Antidepressants in Asia: Report From the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) Projects in 2004 and 2013.

scientific article

Clinical correlates of antipsychotic polytherapy in patients with schizophrenia in Singapore.

scientific article published in June 2004

Clozapine prescription pattern in patients with schizophrenia in Asia: The REAP survey (2016)

scientific article published on 16 March 2019

Clozapine use in schizophrenia: findings of the Research on Asia Psychotropic Prescription (REAP) studies from 2001 to 2009.

scientific article published on 3 September 2011

Common use of antipsychotic polypharmacy in older Asian patients with schizophrenia (2001-2009).

scientific article published in December 2012

Common use of high doses of antipsychotic medications in older Asian patients with schizophrenia (2001-2009).

scientific article

Comparative cost-effectiveness of 11 oral antipsychotics for relapse prevention in schizophrenia within Singapore using effectiveness estimates from a network meta-analysis.

scientific article published on 25 November 2015

Concurrent antipsychotic use in older adults treated with antidepressants in Asia

scientific article published on 07 February 2019

Concurrent benzodiazepine use in older adults treated with antidepressants in Asia

scientific article published on 7 December 2017

Coprescription of mood stabilizers in schizophrenia, dosing, and clinical correlates: An international study

scientific article published on 01 August 2020

Corpus callosum morphology in first-episode and chronic schizophrenia: combined magnetic resonance and diffusion tensor imaging study of Chinese Singaporean patients

scientific article published on 7 November 2013

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years ⬇️

journal article from 'Human Brain Mapping' published in 2022

Cortico-limbic brain anomalies are associated with cognitive subtypes in psychosis: a longitudinal study

scientific article published on 27 April 2020

Country variations in depressive symptoms profile in Asian countries: Findings of the Research on Asia Psychotropic Prescription (REAP) studies.

scientific article published on 13 January 2015

Cross diagnostic comparisons of quality of life deficits in remitted and unremitted patients with schizophrenia and bipolar disorder.

scientific article published on September 2015

De novo Tardive Tourette-like syndrome after prolonged combination depot and oral neuroleptic therapy.

scientific article published in April 2013

Depot antipsychotic use in schizophrenia: an East Asian perspective.

scientific article published in March 2004

Determinants of cognitive function in individuals with type 2 diabetes mellitus: A meta-analysis

scientific article published in February 2018

Diffusion Tensor Imaging Findings of White Matter Changes in First Episode Schizophrenia: A Systematic Review ⬇️

scientific article published on April 30, 2012

Disruption of brain anatomical networks in schizophrenia: A longitudinal, diffusion tensor imaging based study.

scientific article published on 19 January 2016

Dynamic Reorganization of Functional Connectivity Reveals Abnormal Temporal Efficiency in Schizophrenia

scientific article published on 01 April 2019

ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

scientific article published on 29 May 2020

Effects of the neurogranin variant rs12807809 on thalamocortical morphology in schizophrenia

scientific article

Elucidation of shared and specific white matter findings underlying psychopathology clusters in schizophrenia.

scientific article published on September 2017

Epidemiology of completed suicides in Singapore for 2001 and 2002

scientific article published on 01 January 2007

Evidence‐based options for treatment‐resistant adult bipolar disorder patients ⬇️

scientific article published on September 1, 2012

Factors Associated With Antidepressant Dosing in Asia: Findings From the Research on Asian Psychotropic Prescription Study

scientific article

Fatty acid and vitamin interventions in adults with schizophrenia: a systematic review of the current evidence.

scientific article published on 09 September 2015

Fostering resilience in junior doctors: learning from resilience traits and coping strategies of senior physicians

scientific article published in 2021

GRIN2B gene and associated brain cortical white matter changes in bipolar disorder: a preliminary combined platform investigation.

scientific article published on 30 December 2013

Gender differences in Singaporean Chinese patients with schizophrenia.

scientific article published on 12 February 2011

Genetic association studies of glutamate, GABA and related genes in schizophrenia and bipolar disorder: a decade of advance.

scientific article published on 07 January 2010

Genome wide association studies (GWAS) and copy number variation (CNV) studies of the major psychoses: what have we learnt?

scientific article published on 17 September 2011

Genome-wide supported psychosis risk variant in ZNF804A gene and impact on cortico-limbic WM integrity in schizophrenia.

scientific article published on 10 February 2012

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Greater male than female variability in regional brain structure across the lifespan

scientific article published on 12 October 2020

Health-related quality of life and psychiatric comorbidity in first episode psychosis.

scientific article published in July 2005

Hemispheric lateralization abnormalities of the white matter microstructure in patients with schizophrenia and bipolar disorder

scientific article

High dose antipsychotic use in schizophrenia: findings of the REAP (research on east Asia psychotropic prescriptions) study.

scientific article published in July 2004

Hippocampal and parahippocampal volumes in schizophrenia: a structural MRI study.

scientific article

Hippocampal-cortical structural connectivity disruptions in schizophrenia: an integrated perspective from hippocampal shape, cortical thickness, and integrity of white matter bundles.

scientific article

Illness remission status and commissural and associative brain white matter fiber changes in schizophrenia

scientific article published on 02 September 2020

Impact of duration of untreated psychosis and premorbid intelligence on cognitive functioning in patients with first-episode schizophrenia.

scientific article published on 14 April 2016

Increased body mass index makes an impact on brain white-matter integrity in adults with remitted first-episode mania.

scientific article published on 26 April 2013

Increased ratio of 2nd to 4th digit (2D:4D) in schizophrenia.

scientific article published on 18 January 2010

Individual and familial characteristics of youths involved in street corner gangs in Singapore.

scientific article published in August 2003

Informed consent for human genetic and genomic studies: a systematic review.

scientific article published on 18 April 2014

International study on antidepressant prescription pattern at 20 teaching hospitals and major psychiatric institutions in East Asia: Analysis of 1898 cases from China, Japan, Korea, Singapore and Taiwan.

scientific article published on October 2007

International study on antidepressant prescription pattern at 40 major psychiatric institutions and hospitals in Asia: A 10-year comparison study.

scientific article published on 23 February 2015

Lithium treatment for unipolar major depressive disorder: Systematic review

scientific article published on 30 January 2019

Long-term antipsychotic treatment in schizophrenia: systematic review and network meta-analysis of randomised controlled trials

scientific article

Longitudinal neuroimaging and neuropsychological changes in bipolar disorder patients: review of the evidence.

scientific article

Low doses of antipsychotic drugs for hospitalized schizophrenia patients in East Asia: 2004 vs. 2001.

scientific article published on 18 August 2008

Meta-analytic investigations of structural grey matter, executive domain-related functional activations, and white matter diffusivity in obsessive compulsive disorder: an integrative review.

scientific article published on 10 March 2015

Modular-level alterations of structure-function coupling in schizophrenia connectome.

scientific article

Morbidity in Depressive Disorders

scientific article published on 10 February 2017

Neurobiological evidence for thalamic, hippocampal and related glutamatergic abnormalities in bipolar disorder: a review and synthesis.

scientific article

Neurocognitive Functioning in Schizophrenia and Bipolar Disorder: Clarifying Concepts of Diagnostic Dichotomy vs. Continuum.

scientific article published on 05 December 2013

Neurocognitive functioning and quality of life in patients with and without deficit syndrome of schizophrenia

scientific article published on 14 February 2018

Neurocognitive-genetic and neuroimaging-genetic research paradigms in schizophrenia and bipolar disorder.

scientific article

Newer antidepressant drug use in East Asian psychiatric treatment settings: REAP (Research on East Asia Psychotropic Prescriptions) Study

scientific article

Patterns of long acting injectable antipsychotic use and associated clinical factors in schizophrenia among 15 Asian countries and region

scientific article published on 29 May 2020

Perceived Stress, Stigma, Traumatic Stress Levels and Coping Responses amongst Residents in Training across Multiple Specialties during COVID-19 Pandemic-A Longitudinal Study

scientific article published on 09 September 2020

Perceived stress and associated factors among healthcare workers in a primary healthcare setting: the Psychological Readiness and Occupational Training Enhancement during COVID-19 Time (PROTECT) study

scientific article published on 02 December 2020

Persistent, severe hypoglycemia-induced organic brain syndrome with neurological sequelae: a case report ⬇️

scientific article published on June 11, 2011

Physical comorbidities in older adults receiving antidepressants in Asia

scientific article published on 10 July 2018

Physical comorbidity, insight, quality of life and global functioning in first episode schizophrenia: a 24-month, longitudinal outcome study.

scientific article published on 14 August 2006

Polypharmacy and psychotropic drug loading in patients with schizophrenia in Asian countries: Fourth survey of Research on Asian Prescription Patterns on antipsychotics

article

Prevalence and prescription of antidepressants in depression with somatic comorbidity in Asia: the Research on East Asian Psychotropic Prescription Patterns study.

scientific article published on April 2015

Progression from selective to general involvement of hippocampal subfields in schizophrenia

scientific article published on 23 February 2016

Progressive gender differences of structural brain networks in healthy adults: a longitudinal, diffusion tensor imaging study

scientific article

Prolonged Delirium Secondary to Hypoxic-ischemic Encephalopathy Following Cardiac Arrest ⬇️

scientific article published on April 24, 2013

Psychiatric comorbidity in first episode psychosis: the Early Psychosis Intervention Program (EPIP) experience.

scientific article published in January 2004

Psychiatry Teaching Amongst Medical Undergraduates: Stories that Matter and Mediators of Better Learning Outcome

scientific article published on 22 May 2020

Psychosis, Treatment Emergent Extrapyramidal Events, and Subsequent Onset of Huntington's Disease: A Case Report and Review of the Literature.

scientific article published on August 2016

Psychosocial and coping responses within the community health care setting towards a national outbreak of an infectious disease.

scientific article

Psychotropic drug-prescribing correlates of disorganized speech in Asians with schizophrenia: The REAP-AP study

scientific article published on 13 November 2018

QTc prolongation in schizophrenia patients in Asia: clinical correlates and trends between 2004 and 2008/2009.

scientific article

Randomized Controlled Trials of Psychoeducation Modalities in the Management of Bipolar Disorder

scientific article published on 01 May 2018

Rare neuropsychiatric sequelae following neuroleptic malignant syndrome: a case report and review of the literature.

scientific article published on 7 August 2008

Recognition of Schizophrenia with Regularized Support Vector Machine and Sequential Region of Interest Selection using Structural Magnetic Resonance Imaging

scientific article published in Scientific Reports

Reduced Hemispheric Asymmetry of Brain Anatomical Networks Is Linked to Schizophrenia: A Connectome Study.

scientific article published on 26 October 2015

Regionally specific white matter disruptions of fornix and cingulum in schizophrenia.

scientific article

Resolution of tardive dystonia in a patient with bipolar disorder treated with clozapine: a case report.

scientific article published on 22 September 2009

Reversible delayed onset olanzapine-associated leukopenia and neutropenia in a clozapine-naive patient on concomitant depot antipsychotic

scientific article published on 01 August 2007

Robust curve clustering based on a multivariate t-distribution model.

scientific article published on 14 October 2010

Sex differences in use of psychotropic drugs and drug-induced side effects in schizophrenia patients: findings of the Research on Asia Psychotropic Prescription (REAP) studies.

scientific article published on 13 December 2010

Shared and divergent neurocognitive impairments in adult patients with schizophrenia and bipolar disorder: Whither the evidence?

scientific article published on 12 December 2015

Structural connectivity analysis reveals topological aberrations in patients with schizophrenia.

scientific article published in January 2013

Tardive dyskinesia in the treatment of schizophrenia: the findings of the Research on Asian Psychotropic Prescription Pattern (REAP) survey (2001 - 2009)

scientific article published on 01 June 2011

Testing models of thalamic dysfunction in schizophrenia using neuroimaging.

scientific article

The 23-Hour Observation Unit Admissions Within the Emergency Service at a National Tertiary Psychiatric Hospital: Clarifying Clinical Profiles, Outcomes, and Predictors of Subsequent Hospitalization.

scientific article

The Schizophrenia Cognition Rating Scale: validation of an interview-based assessment of cognitive functioning in Asian patients with schizophrenia.

scientific article published on 6 May 2010

The association between rare large duplication of 16p11.2 and schizophrenia in the Singaporean Chinese population

article

The effectiveness of antidepressant monotherapy in a naturalistic outpatient setting.

scientific article published on 4 October 2012

The genetic architecture of the human cerebral cortex

scientific article

The impact of genome wide supported microRNA-137 (MIR137) risk variants on frontal and striatal white matter integrity, neurocognitive functioning, and negative symptoms in schizophrenia.

scientific article published on 29 April 2015

The prevalence of tardive dyskinesia in Chinese Singaporean patients with schizophrenia: revisited

scientific article published on 01 June 2010

Therapeutic Misconception in Psychiatry Research: A Systematic Review.

scientific article published on February 2016

Tracking cerebral white matter changes across the lifespan: insights from diffusion tensor imaging studies.

scientific article published on 18 January 2013

Use of anticholinergic drugs in patients with schizophrenia in Asia from 2001 to 2009.

scientific article published on 13 April 2011

Use of electroconvulsive therapy for Asian patients with schizophrenia (2001-2009): Trends and correlates.

scientific article

Use of first- and second-generation antipsychotic medications in older patients with schizophrenia in Asia (2001-2009).

scientific article published on 11 July 2012

Use of narratives to enhance learning of research ethics in residents and researchers

scientific article

Use of normative distribution of gray to white matter ratio in orthogonal planes in human brain studies and computer-assisted neuroradiology

scientific article published on 16 December 2010

Validated five-factor model of Positive and Negative Syndrome Scale for schizophrenia in Chinese population ⬇️

scientific article published on November 11, 2012

Valproate-induced hyperammonemia in mental retardation: a case report and review of the literature.

scientific article published on 23 February 2010

Virtual Ontogeny of Cortical Growth Preceding Mental Illness

scientific article published in 2022

White matter abnormalities in first-episode schizophrenia: a combined structural MRI and DTI study.

scientific article published on 6 January 2010

White matter abnormalities in major depression: Evidence from post-mortem, neuroimaging and genetic studies ⬇️

scientific article published on October 2, 2010

Paulina is supported by:

About Paulina

Help