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List of works by Fijs W.B. van Leeuwen

(Near-Infrared) Fluorescence-Guided Surgery Under Ambient Light Conditions: A Next Step to Embedment of the Technology in Clinical Routine

scientific article published on 28 March 2016

(Non-targeted) radioactive/fluorescent nanoparticles and their potential in combined pre- and intraoperative imaging during sentinel lymph node resection.

scientific article

A controlled human Schistosoma mansoni infection model to advance novel drugs, vaccines and diagnostics

scientific article published on 17 February 2020

A hybrid radioactive and fluorescent tracer for sentinel node biopsy in penile carcinoma as a potential replacement for blue dye.

scientific article published on 26 November 2013

A pilot study of SPECT/CT-based mixed-reality navigation towards the sentinel node in patients with melanoma or Merkel cell carcinoma of a lower extremity.

scientific article

Added value of the hybrid tracer indocyanine green-99mTc-nanocolloid for sentinel node biopsy in a series of patients with different lymphatic drainage patterns.

scientific article published on 6 April 2013

Advances in sentinel node dissection in prostate cancer from a technical perspective

scientific article

Advancing intraoperative magnetic tracing using 3D freehand magnetic particle imaging

scientific article published on 31 July 2021

An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime

scientific article published in September 2014

An innovative multimodality approach for sentinel node mapping and biopsy in head and neck malignancies.

scientific article published on 16 May 2014

Biomarkers in preclinical cancer imaging.

scientific article

COvalent monolayer patterns in Microfluidics by PLasma etching Open Technology - COMPLOT

scientific article published on 01 March 2020

Clinical trial of combined radio- and fluorescence-guided sentinel lymph node biopsy in breast cancer ⬇️

scientific article published on May 21, 2013

Comparing the hybrid fluorescent-radioactive tracer indocyanine green-99mTc-nanocolloid with 99mTc-nanocolloid for sentinel node identification: a validation study using lymphoscintigraphy and SPECT/CT.

scientific article published on 29 May 2012

Crossing technological frontiers in radioguided intervention.

scientific article published on 9 August 2016

Current Perspectives in the Use of Molecular Imaging To Target Surgical Treatments for Genitourinary Cancers ⬇️

scientific article published on August 7, 2013

Cyclodextrin/Adamantane-Mediated Targeting of Inoculated Bacteria in Mice

scientific article published on 23 February 2021

Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met

scientific article published on 13 July 2015

Development and prospects of dedicated tracers for the molecular imaging of bacterial infections.

scientific article

Development of a Hybrid Tracer for SPECT and Optical Imaging of Bacterial Infections.

scientific article

Diffusion-weighted-preparation (D-prep) MRI as a future extension of SPECT/CT based surgical planning for sentinel node procedures in the head and neck area?

scientific article published on 7 July 2016

Dual-emissive quantum dots for multispectral intraoperative fluorescence imaging.

scientific article published on 18 June 2010

Early Induction of Human Regulatory Dermal Antigen Presenting Cells by Skin-Penetrating Cercariae

scientific article published on 31 October 2018

Evaluation of a Fluorescent and Radiolabeled Hybrid Somatostatin Analog In Vitro and in Mice Bearing H69 Neuroendocrine Xenografts.

scientific article published on 28 April 2016

Feasibility of intraoperative navigation to the sentinel node in the groin using preoperatively acquired single photon emission computerized tomography data: transferring functional imaging to the operating room.

scientific article

Feasibility of sentinel node biopsy in head and neck melanoma using a hybrid radioactive and fluorescent tracer

scientific article

First Robotic SPECT for Minimally Invasive Sentinel Lymph Node Mapping

scientific article published on 5 November 2015

First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

scientific article published on 25 June 2015

Fluorescence guidance during radical prostatectomy

scientific article published on 2 January 2014

Fluorescence guidance in urologic surgery ⬇️

scientific article published on March 1, 2012

Fluorescence guided surgery and tracer-dose, fact or fiction?

scientific article

Fluorescent lectins for local in vivo visualization of peripheral nerves

scientific article published on 08 July 2014

Fluorescent radiocolloids: are hybrid tracers the future for lymphatic mapping?

scientific article published on 22 July 2015

Hybrid Surgical Guidance: Does Hardware Integration of γ- and Fluorescence Imaging Modalities Make Sense?

scientific article published on 29 September 2016

Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression.

scientific article

Hybrid radioguided occult lesion localization (hybrid ROLL) of (18)F-FDG-avid lesions using the hybrid tracer indocyanine green-(99m)Tc-nanocolloid

scientific article published on 9 May 2016

Hybrid surgical guidance based on the integration of radionuclear and optical technologies

scientific article

Image navigation as a means to expand the boundaries of fluorescence-guided surgery.

scientific article published in May 2012

Image-Guided Surgery: Are We Getting the Most Out of Small-Molecule Prostate-Specific-Membrane-Antigen-Targeted Tracers?

scientific article published on 06 January 2020

Image-guided hepatopancreatobiliary surgery using near-infrared fluorescent light

scientific article

Imaging agents for the chemokine receptor 4 (CXCR4).

scientific article published on 28 June 2012

Immunohistochemical Detection of the CXCR4 Expression in Tumor Tissue Using the Fluorescent Peptide Antagonist Ac-TZ14011-FITC ⬇️

scientific article published on August 1, 2011

Interventional nuclear medicine: "click" chemistry as an <i>in vivo</i> targeting strategy for imaging microspheres and bacteria

scientific article published on 07 January 2021

Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer

scientific article

Intraoperative visualization of nerves using a myelin protein-zero specific fluorescent tracer

scientific article published on 29 May 2021

Ionizable (Thia)calix[4]crowns as highly selective 226Ra2+ ionophores

scientific article published on 01 July 2005

Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature

scientific article published on 21 November 2011

Luminescence-based Imaging Approaches in the Field of Interventional Molecular Imaging.

scientific article published on July 2015

MMP-2/9-Specific Activatable Lifetime Imaging Agent

scientific article published on 12 May 2015

Multimodal Surgical Guidance during Sentinel Node Biopsy for Melanoma: Combined Gamma Tracing and Fluorescence Imaging of the Sentinel Node through Use of the Hybrid Tracer Indocyanine Green-(99m)Tc-Nanocolloid

scientific article

Multimodal Tracking of Controlled Staphylococcus aureus Infections in Mice

scientific article published on 02 May 2019

Multimodal hybrid imaging agents for sentinel node mapping as a means to (re)connect nuclear medicine to advances made in robot-assisted surgery

scientific article published on 15 January 2016

Multimodal surgical guidance towards the sentinel node in vulvar cancer.

scientific article published on 17 September 2013

Multimodal tumor-targeting peptides functionalized with both a radio- and a fluorescent label.

scientific article published on October 2010

Multispectral Fluorescence Imaging During Robot-assisted Laparoscopic Sentinel Node Biopsy: A First Step Towards a Fluorescence-based Anatomic Roadmap

scientific article published on 23 June 2016

Multispectral visualization of surgical safety-margins using fluorescent marker seeds ⬇️

scientific article published on March 28, 2012

Navigation of a robot-integrated fluorescence laparoscope in preoperative SPECT/CT and intraoperative freehand SPECT imaging data: a phantom study.

scientific article

On-Flow Immobilization of Polystyrene Microspheres on β-Cyclodextrin-Patterned Silica Surfaces through Supramolecular Host-Guest Interactions

scientific article published on 18 September 2019

Optical imaging as an expansion of nuclear medicine: Cerenkov-based luminescence vs fluorescence-based luminescence.

scientific article published on 15 May 2013

Optimisation of fluorescence guidance during robot-assisted laparoscopic sentinel node biopsy for prostate cancer

scientific article published on 3 August 2014

Peptide-functionalized luminescent iridium complexes for lifetime imaging of CXCR4 expression.

scientific article published on 7 July 2011

Perspectives on translational molecular imaging and therapy: an overview of key questions to be addressed

scientific article published on 02 June 2022

Phosphorescence imaging of living cells with amino acid-functionalized tris(2-phenylpyridine)iridium(III) complexes.

scientific article published on 3 February 2012

Photocontrolled release and uptake of a porphyrin guest by dithienylethene-tethered beta-cyclodextrin host dimers.

scientific article published in March 2004

Potential value of color-coded dynamic breast-specific gamma-imaging; comparing (99m)Tc-(V)-DMSA, (99m)Tc-MIBI, and (99m)Tc-HDP in a mouse mammary tumor model

scientific article published on 16 May 2010

Radium-223 chloride: Extending life in prostate cancer patients by treating bone metastases.

scientific article

Regulatory strategies in the complexation and release of a noncovalent guest trimer by a self-assembled molecular cage

scientific article published on 01 December 2003

Relationship between intraprostatic tracer deposits and sentinel lymph node mapping in prostate cancer patients.

scientific article published on 29 May 2012

Reply from authors re: Francesco Montorsi, Giorgio Gandaglia. Sentinel node biopsy for prostate cancer: a useless surgical exercise? Eur urol 2014;66:999-1000: Removing nodes that count rather than counting nodes that don't.

scientific article published on 13 October 2014

Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation.

scientific article

Selective self-organization of guest molecules in self-assembled molecular boxes.

scientific article

Self-assembled ionophores from isoguanosine: diffusion NMR spectroscopy clarifies cation's and anion's influence on supramolecular structure

scientific article published on 01 January 2007

Sentinel Lymph Node Biopsy for Prostate Cancer: A Hybrid Approach ⬇️

scientific article published on March 14, 2013

Sentinel Node Procedure in Prostate Cancer: A Systematic Review to Assess Diagnostic Accuracy

scientific article

Size and affinity kinetics of nanobodies influence targeting and penetration of solid tumours

scientific article published on 14 November 2019

Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.

scientific article published on 5 May 2016

Surgical Guidance in Prostate Cancer: "From Molecule to Man" Translations.

scientific article

Synthesis and conformational evaluation of p-tert-butylthiacalix[4]arene-crowns

scientific article published on 01 May 2004

Tailoring Fluorescent Dyes To Optimize a Hybrid RGD-Tracer.

scientific article published on 13 April 2016

Thiacalix[4]arene derivatives as radium ionophores: a study on the requirements for Ra2+ extraction.

scientific article published on 21 April 2005

Toward (Hybrid) Navigation of a Fluorescence Camera in an Open Surgery Setting

scientific article published on 26 May 2016

Tumor bracketing and safety margin estimation using multimodal marker seeds: a proof of concept.

scientific article published in September 2010

U-SPECT-BioFluo: an integrated radionuclide, bioluminescence, and fluorescence imaging platform

scientific article published on 11 October 2014

Validation of intratracheal instillation of lung tumour cells in mice using single photon emission computed tomography/computed tomography imaging.

scientific article published on 23 October 2009

uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery

scientific article

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