List of works by Erik van Werkhoven

A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy

scientific article published on 11 December 2018

Adjuvant dose-dense doxorubicin-cyclophosphamide versus docetaxel-doxorubicin-cyclophosphamide for high-risk breast cancer: First results of the randomised MATADOR trial (BOOG 2004-04)

scientific article published on 01 October 2018

Advanced Age is Not a Contraindication for Treatment With Curative Intent in Esophageal Cancer.

scientific article

Always randomize as late as possible

scientific article published on 08 April 2019

An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome.

scientific article published on 22 December 2016

Angiotensin II-Receptor Inhibition With Candesartan to Prevent Trastuzumab-Related Cardiotoxic Effects in Patients With Early Breast Cancer: A Randomized Clinical Trial.

scientific article published on 23 June 2016

Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy

scientific article published on 16 August 2012

Blood and lymphatic microvessel damage in irradiated human skin: The role of TGF-β, endoglin and macrophages.

scientific article published on 4 September 2015

Clinical Relevance of Incidental Prostatic Lesions on FDG-Positron Emission Tomography/Computerized Tomography-Should Patients Receive Further Evaluation?

scientific article published on 17 November 2015

Contralateral regional recurrence after elective unilateral neck irradiation in oropharyngeal carcinoma: A literature-based critical review

scientific article published on 21 July 2017

Detection of endogenously circulating mesenchymal stem cells in human cancer patients

scientific article published on 17 September 2018

Determinants of treatment waiting times for head and neck cancer in the Netherlands and their relation to survival.

scientific article published on 22 December 2014

Differences in histopathological evaluation of standard lymph node dissections result in differences in nodal count but not in survival.

scientific article published on 9 August 2012

Effect of preservation of the right gastro-epiploic artery on delayed gastric emptying after cytoreductive surgery and HIPEC: a randomized clinical trial

scientific article published on 08 January 2011

Endo-Urological Techniques for Benign Uretero-Ileal Strictures Have Poor Efficacy and Affect Renal Function

scientific article published on 18 August 2017

External validation of a predictive model of survival after cytoreductive nephrectomy for metastatic renal cell carcinoma

scientific article published on 01 August 2018

Factors associated with patient-reported cosmetic outcome in the Young Boost Breast Trial.

scientific article published on 28 May 2016

Human papillomavirus prevalence in invasive penile cancer and association with clinical outcome.

scientific article

Identifying pathologic complete response of the breast after neoadjuvant systemic therapy with ultrasound guided biopsy to eventually omit surgery: Study design and feasibility of the MICRA trial (Minimally Invasive Complete Response Assessment).

scientific article published on 23 April 2018

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial

scientific article published on 13 May 2019

Implementation of a Multicenter Biobanking Collaboration for Next-Generation Sequencing-Based Biomarker Discovery Based on Fresh Frozen Pretreatment Tumor Tissue Biopsies.

scientific article published on 23 September 2016

Increased risk of severe fluoropyrimidine-associated toxicity in patients carrying a G to C substitution in the first 28-bp tandem repeat of the thymidylate synthase 2R allele.

scientific article published on 18 July 2015

Independent replication of polymorphisms predicting toxicity in breast cancer patients randomized between dose-dense and docetaxel-containing adjuvant chemotherapy.

scientific article published on 27 November 2017

Induction chemotherapy followed by surgery in node positive bladder cancer

scientific article published on 15 November 2013

Inguinal recurrence following therapeutic lymphadenectomy for node positive penile carcinoma: outcome and implications for management

scientific article published on 15 January 2011

Intensive Imaging-based Follow-up of Surgically Treated Localised Renal Cell Carcinoma Does Not Improve Post-recurrence Survival: Results from a European Multicentre Database (RECUR)

scientific article published on 11 October 2018

Intravesical recurrence after bladder sparing treatment of small cell carcinoma of the bladder: Characteristics, treatment, and outcome

scientific article published on 23 March 2018

Long term cerebral and vascular complications after irradiation of the neck in head and neck cancer patients: a prospective cohort study: study rationale and protocol

scientific article

Long-term Outcomes of Follow-up for Initially Localised Clear Cell Renal Cell Carcinoma: RECUR Database Analysis.

scientific article published on 7 March 2018

Management and prognostic factors of epithelioid trophoblastic tumors: Results from the International Society for the Study of Trophoblastic Diseases database

scientific article published on 22 November 2018

Neoadjuvant chemotherapy adaptation and serial MRI response monitoring in ER-positive HER2-negative breast cancer

scientific article published on 22 October 2013

Neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2 blockade for HER2-positive breast cancer (TRAIN-2): a multicentre, open-label, randomised, phase 3 trial

scientific article published on 06 November 2018

Neoadjuvant taxane-based combination chemotherapy in patients with advanced penile cancer

scientific article published on 08 June 2014

Nephrotoxicity as a Dose-Limiting Factor in a High-Dose Cisplatin-Based Chemoradiotherapy Regimen for Head and Neck Carcinomas

scientific article published on 16 February 2016

Nomogram to predict ipsilateral breast relapse based on pathology review from the EORTC 22881-10882 boost versus no boost trial.

scientific article published on July 2011

POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients

scientific article published on 22 August 2019

Patient reported outcomes following stereotactic ablative radiotherapy or surgery for stage IA non-small-cell lung cancer: Results from the ROSEL multicenter randomized trial

scientific article published in October 2015

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients

scientific article published on 01 October 2019

Penile cancer stage, survival and body mass index.

scientific article published on 20 January 2015

Penile sparing surgery for penile cancer-does it affect survival?

scientific article published on 25 December 2013

Phase 1 and pharmacological study of olaparib in combination with high-dose radiotherapy with and without concurrent cisplatin for non-small cell lung cancer

scientific article published on 01 December 2020

Phase I dose-escalation study and population pharmacokinetic analysis of fixed dose rate gemcitabine plus carboplatin as second-line therapy in patients with ovarian cancer.

scientific article

Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids.

scientific article published on 24 March 2018

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

scientific article published on 25 October 2014

Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months

scientific article

Predicting clinical benefit from everolimus in patients with advanced solid tumors, the CPCT-03 study

scientific article

Prediction of acute toxicity grade ≥ 3 in patients with locally advanced non-small-cell lung cancer receiving intensity modulated radiotherapy and concurrent low-dose Cisplatin

scientific article published on 05 July 2013

Predictors for poor cosmetic outcome in patients with early stage breast cancer treated with breast conserving therapy: Results of the Young boost trial

scientific article published on 03 July 2018

Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity

scientific article published on 20 April 2017

Prognostic Factors for Local Control in Breast Cancer After Long-term Follow-up in the EORTC Boost vs No Boost Trial: A Randomized Clinical Trial

scientific article published on 08 September 2016

Prognostic Value of Residual Disease after Neoadjuvant Therapy in HER2-Positive Breast Cancer Evaluated by Residual Cancer Burden, Neoadjuvant Response Index, and Neo-Bioscore

scientific article published on 10 May 2019

Prognostic factors for occult inguinal lymph node involvement in penile carcinoma and assessment of the high-risk EAU subgroup: a two-institution analysis of 342 clinically node-negative patients.

scientific article published on 18 August 2010

Progression of carotid intima media thickness after radiotherapy: a long-term prospective cohort study.

scientific article published on 14 November 2014

Prophylactic pelvic lymph node dissection in patients with penile cancer.

scientific article published on 10 December 2014

Prospective cohort study of carotid intima-media thickness after irradiation.

scientific article published on 7 October 2014

Prostate sparing cystectomy for bladder cancer: A two-center study

scientific article published on 08 June 2018

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial

scientific article published on 01 July 2019

Randomised study of tegafur-uracil plus leucovorin versus capecitabine as first-line therapy in elderly patients with advanced colorectal cancer--TLC study.

scientific article

Randomized phase III trial of S-1 versus capecitabine in the first-line treatment of metastatic colorectal cancer: SALTO study by the Dutch Colorectal Cancer Group.

scientific article

Response to induction chemotherapy and surgery in non-organ confined bladder cancer: a single institution experience

scientific article published on 31 January 2013

Short-term outcome after cystectomy: comparison of early oral feeding in an enhanced recovery protocol and feeding using Bengmark nasojejunal tube

scientific article published on 22 November 2017

The best of both worlds: a hybrid approach for optimal pre- and intraoperative identification of sentinel lymph nodes

scientific article published on 25 April 2018

The performance of model-based versus rule-based phase I clinical trials in oncology : A quantitative comparison of the performance of model-based versus rule-based phase I trials with molecularly targeted anticancer drugs over the last 2 years.

scientific article published on 10 March 2016

The prognostic value of the neoadjuvant response index in triple-negative breast cancer: validation and comparison with pathological complete response as outcome measure

scientific article

The time to progression ratio: a new individualized volumetric parameter for the early detection of clinical benefit of targeted therapies

scientific article published on 27 May 2016

The use of radioactive iodine-125 seed localization in patients with non-palpable breast cancer: a comparison with the radioguided occult lesion localization with 99m technetium.

scientific article published on 3 February 2015

Toxicity of dual HER2-blockade with pertuzumab added to anthracycline versus non-anthracycline containing chemotherapy as neoadjuvant treatment in HER2-positive breast cancer: The TRAIN-2 study.

scientific article published on 4 August 2016

Trastuzumab in combination with weekly paclitaxel and carboplatin as neo-adjuvant treatment for HER2-positive breast cancer: The TRAIN-study.

scientific article

Tumor volume as a prognostic factor for local control and overall survival in advanced larynx cancer

scientific article published on 29 August 2015

Ultrasound examination and fine needle aspiration cytology-useful for followup of the regional nodes in penile cancer?

scientific article published on 28 August 2013

Very low local recurrence rates after breast-conserving therapy: analysis of 8485 patients treated over a 28-year period

scientific article

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