List of works - Keith Gull

3D Architecture of the Trypanosoma brucei Flagella Connector, a Mobile Transmembrane Junction

scientific article

9+2 to 9+0 axoneme conversion in Leishmania.

scientific article

A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions.

scientific article

A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components

scientific article

A Trypanosoma brucei Protein Required for Maintenance of the Flagellum Attachment Zone and Flagellar Pocket ER Domains ⬇️

scientific article published on December 18, 2011

A cell-body groove housing the new flagellum tip suggests an adaptation of cellular morphogenesis for parasitism in the bloodstream form of Trypanosoma brucei.

scientific article

A dynamic coordination of flagellum and cytoplasmic cytoskeleton assembly specifies cell morphogenesis in trypanosomes.

scientific article published on 3 March 2015

A meckelin-filamin A interaction mediates ciliogenesis

scientific article

A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology.

scientific article

A new generation of T7 RNA polymerase-independent inducible expression plasmids for Trypanosoma brucei

scientific article

A protein-protein interaction map of the Trypanosoma brucei paraflagellar rod.

scientific article

A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei

scientific article

A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids.

scientific article

Ab initio identification of novel regulatory elements in the genome of Trypanosoma brucei by Bayesian inference on sequence segmentation

scientific article

An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei

scientific article

Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei

scientific article

Basal body multipotency and axonemal remodelling are two pathways to a 9+0 flagellum.

scientific article

Basal body structure and cell cycle-dependent biogenesis in Trypanosoma brucei

scientific article

Basalin is an evolutionarily unconstrained protein revealed via a conserved role in flagellum basal plate function

scientific article published on 27 February 2019

Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans

scientific article

Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation

scientific article

Calmodulin is required for paraflagellar rod assembly and flagellum-cell body attachment in trypanosomes.

scientific article published on 19 June 2013

Cell biology of the trypanosome genome

scientific article

Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes.

scientific article published on 12 August 2016

Combining RNA interference mutants and comparative proteomics to identify protein components and dependences in a eukaryotic flagellum

scientific article

Comparative genomics and concerted evolution of beta-tubulin paralogs in Leishmania spp.

scientific article

Conservation of ciliary proteins in plants with no cilia

scientific article

Coordination of the Cell Cycle in Trypanosomes

scientific article published on 01 September 2019

Correction to 'Shape, form, function and pathogenicity: from textbook descriptions to biological understanding'

scientific article published on 01 August 2018

Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei.

scientific article

Cryptic paraflagellar rod in endosymbiont-containing kinetoplastid protozoa

scientific article

Cytokinesis in Trypanosoma brucei differs between bloodstream and tsetse trypomastigote forms: implications for microtubule-based morphogenesis and mutant analysis.

scientific article published on 15 November 2013

Dependency relationships between IFT-dependent flagellum elongation and cell morphogenesis in

scientific article published on 21 November 2018

Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis

scientific article

Direction of flagellum beat propagation is controlled by proximal/distal outer dynein arm asymmetry

article published in the Proceedings of the National Academy of Sciences of the United States of America

Discovery of unconventional kinetochores in kinetoplastids.

scientific article published on 27 February 2014

Evidence for loss of a partial flagellar glycolytic pathway during trypanosomatid evolution

scientific article

Flagellar pocket restructuring through the Leishmania life cycle involves a discrete flagellum attachment zone.

scientific article published on 08 January 2016

Genome sequencing reveals metabolic and cellular interdependence in an amoeba-kinetoplastid symbiosis.

scientific article published on 15 September 2017

Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei.

scientific article

Host-parasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies

scientific article

Identification of paralogous life-cycle stage specific cytoskeletal proteins in the parasite Trypanosoma brucei

scientific article

Integration of pZJM library plasmids into unexpected locations in the Trypanosoma brucei genome

scientific article

Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes.

scientific article

Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1

scientific article

Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology.

scientific article

Modulation of flagellum attachment zone protein FLAM3 and regulation of the cell shape in Trypanosoma brucei life cycle transitions.

scientific article published on 6 July 2015

More than one way to build a flagellum: comparative genomics of parasitic protozoa

scientific article

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton

scientific journal article

Non-equivalence in old- and new-flagellum daughter cells of a proliferative division in Trypanosoma brucei

scientific article published on 25 July 2019

Patterns of kinesin evolution reveal a complex ancestral eukaryote with a multifunctional cytoskeleton

scientific article

Protein diversity in discrete structures at the distal tip of the trypanosome flagellum.

scientific article published on 19 July 2017

Reconstructing the evolutionary history of the centriole from protein components

scientific article

Shape, form, function and Leishmania pathogenicity: from textbook descriptions to biological understanding

scientific article published on September 2017

Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast

scientific article

System dynamic modelling to assess economic viability and risk trade-offs for ecological restoration in South Africa.

scientific article published on 22 March 2013

The Flagellum Attachment Zone: 'The Cellular Ruler' of Trypanosome Morphology

scientific article

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

scientific article

The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation

scientific article

The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology

scientific article

The evolution of land plant cilia

scientific article

The evolution of the cytoskeleton

scientific article

The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear roles

scientific article (publication date: 23 November 2010)

The frequency of gene targeting in Trypanosoma brucei is independent of target site copy number

scientific article

The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules

scientific article

The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis.

scientific article

The limits on trypanosomatid morphological diversity

scientific article (publication date: 2013)

The paraflagellar rod of kinetoplastid parasites: from structure to components and function

scientific article

Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography

scientific article

Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes

scientific article

flagellum attachment zone is critical for flagellar pocket shape, development in the sand fly, and pathogenicity in the host

article

List of works by Keith Gull

3D Architecture of the Trypanosoma brucei Flagella Connector, a Mobile Transmembrane Junction

9+2 to 9+0 axoneme conversion in Leishmania.

A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions.

A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components

A Trypanosoma brucei Protein Required for Maintenance of the Flagellum Attachment Zone and Flagellar Pocket ER Domains ⬇️

A cell-body groove housing the new flagellum tip suggests an adaptation of cellular morphogenesis for parasitism in the bloodstream form of Trypanosoma brucei.

A dynamic coordination of flagellum and cytoplasmic cytoskeleton assembly specifies cell morphogenesis in trypanosomes.

A meckelin-filamin A interaction mediates ciliogenesis

A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology.

A new generation of T7 RNA polymerase-independent inducible expression plasmids for Trypanosoma brucei

A protein-protein interaction map of the Trypanosoma brucei paraflagellar rod.

A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei

A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids.

Ab initio identification of novel regulatory elements in the genome of Trypanosoma brucei by Bayesian inference on sequence segmentation

An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei

Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei

Basal body multipotency and axonemal remodelling are two pathways to a 9+0 flagellum.

Basal body structure and cell cycle-dependent biogenesis in Trypanosoma brucei

Basalin is an evolutionarily unconstrained protein revealed via a conserved role in flagellum basal plate function

Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans

Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation

Calmodulin is required for paraflagellar rod assembly and flagellum-cell body attachment in trypanosomes.

Cell biology of the trypanosome genome

Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes.

Combining RNA interference mutants and comparative proteomics to identify protein components and dependences in a eukaryotic flagellum

Comparative genomics and concerted evolution of beta-tubulin paralogs in Leishmania spp.

Conservation of ciliary proteins in plants with no cilia

Coordination of the Cell Cycle in Trypanosomes

Correction to 'Shape, form, function and pathogenicity: from textbook descriptions to biological understanding'

Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei.

Cryptic paraflagellar rod in endosymbiont-containing kinetoplastid protozoa

Cytokinesis in Trypanosoma brucei differs between bloodstream and tsetse trypomastigote forms: implications for microtubule-based morphogenesis and mutant analysis.

Dependency relationships between IFT-dependent flagellum elongation and cell morphogenesis in

Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis

Direction of flagellum beat propagation is controlled by proximal/distal outer dynein arm asymmetry

Discovery of unconventional kinetochores in kinetoplastids.

Evidence for loss of a partial flagellar glycolytic pathway during trypanosomatid evolution

Flagellar pocket restructuring through the Leishmania life cycle involves a discrete flagellum attachment zone.

Genome sequencing reveals metabolic and cellular interdependence in an amoeba-kinetoplastid symbiosis.

Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei.

Host-parasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies

Identification of paralogous life-cycle stage specific cytoskeletal proteins in the parasite Trypanosoma brucei

Integration of pZJM library plasmids into unexpected locations in the Trypanosoma brucei genome

Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes.

Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1

Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology.

Modulation of flagellum attachment zone protein FLAM3 and regulation of the cell shape in Trypanosoma brucei life cycle transitions.

More than one way to build a flagellum: comparative genomics of parasitic protozoa

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton

Non-equivalence in old- and new-flagellum daughter cells of a proliferative division in Trypanosoma brucei

Patterns of kinesin evolution reveal a complex ancestral eukaryote with a multifunctional cytoskeleton

Protein diversity in discrete structures at the distal tip of the trypanosome flagellum.

Reconstructing the evolutionary history of the centriole from protein components

Shape, form, function and Leishmania pathogenicity: from textbook descriptions to biological understanding

Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast

System dynamic modelling to assess economic viability and risk trade-offs for ecological restoration in South Africa.

The Flagellum Attachment Zone: 'The Cellular Ruler' of Trypanosome Morphology

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation

The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology

The evolution of land plant cilia

The evolution of the cytoskeleton

The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear roles

The frequency of gene targeting in Trypanosoma brucei is independent of target site copy number

The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules

The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis.

The limits on trypanosomatid morphological diversity

The paraflagellar rod of kinetoplastid parasites: from structure to components and function

Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography

Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes

flagellum attachment zone is critical for flagellar pocket shape, development in the sand fly, and pathogenicity in the host