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List of works by Keith Black

116 Deep high-plex spatial phenotyping of glioblastoma multiforme provides new insights into the immune landscape and tumor heterogeneity

scientific article published in November 2022

A Combination of Tri-Leucine and Angiopep-2 Drives a Polyanionic Polymalic Acid Nanodrug Platform Across the Blood-Brain Barrier

scientific article published on 16 January 2019

A Phase I Study of Autologous Dendritic Cell Vaccine Pulsed with Allogeneic Stem-like Cell Line Lysate in Patients with Newly Diagnosed or Recurrent Glioblastoma

scientific article published on 2 December 2021

A herpes simplex virus type 1 mutant with gamma 34.5 and LAT deletions effectively oncolyses human U87 glioblastomas in nude mice

scientific article published in March 2002

A high-definition exoscope system for neurosurgery and other microsurgical disciplines: preliminary report

scientific article

A novel role for osteopontin in macrophage-mediated amyloid-β clearance in Alzheimer's models.

scientific article published on 28 August 2017

A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells

scientific article published on 30 November 2005

A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma

scientific article published on 10 March 2020

ACE overexpression in myelomonocytic cells: effect on a mouse model of Alzheimer's disease

scientific article

ACTR-49. PHASE 1 SAFETY STUDY OF BLZ-100 FOR FLUORESCENCE-GUIDED RESECTION OF GLIOMA IN ADULT SUBJECTS

AIM-2: a novel tumor antigen is expressed and presented by human glioma cells

scientific article

ALK-anaplastic Large Cell Lymphoma of the Small Bowel: A Case Report

scholarly article

ATIM-18. A PHASE I TRIAL OF VACCINATION WITH AUTOLOGOUS DENDRITIC CELLS PULSED WITH LYSATE DERIVED FROM AN ALLOGENEIC GLIOBLASTOMA STEMLIKE CELL LINE FOR PATIENTS WITH NEWLY DIAGNOSED OR RECURRENT GLIOBLASTOMA

ATIM-25. TEN-YEAR FOLLOW UP WITH LONG TERM REMISSION IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM) TREATED WITH ICT-107 VACCINE (PHASE I)

scientific article published in November 2016

ATNT-16PHASE 1 DOSE ESCALATION AND EXPANSION SAFETY STUDY OF BLZ-100 FOR FLUORESCENCE GUIDED RESECTION OF GLIOMA IN ADULTS.

scientific article

Abnormal CD8 T cells induce and track Alzheimer’s-like neurodegeneration

scientific article published on 26 February 2021

Abstract 1896: Blockade of laminin-411-notch crosstalk as an effective therapy for glioblastoma treatment

scientific article published in July 2019

Abstract 575: Brain delivery of clinically suitable nanobioconjugates to inhibit glioblastoma growth through extracellular matrix-immune cell crosstalk

scientific article published on 4 April 2023

Abstract 977: Nano immunotherapeutics crossing blood-brain barrier to activate local brain tumor immune system

scholarly article

Abstract 977: Nano immunotherapeutics crossing blood-brain barrier to activate local brain tumor immune system

scientific article published in July 2019

Abstract P55: Retinal Microvascular Parameters Predict Retinal Amyloid Burden and Co-Jointly Predict Verbal Memory

scientific article published in March 2021

Abstract TP23: Differentiated Para-Vascular Distribution of Amyloid Plaques in Normal versus Cognitively Impaired

scientific article published in February 2024

Activated Bone Marrow-Derived Macrophages Eradicate Alzheimer's-Related Aβ42 Oligomers and Protect Synapses

scientific article published on 31 January 2020

Activated T cell therapy targeting glioblastoma cancer stem cells

scientific article published on 5 January 2023

Acute neuropathological consequences of short-term mechanical ventilation in wild-type and Alzheimer's disease mice

scientific article published on 22 February 2019

Adenosine 5'-triphosphate-sensitive potassium channel-mediated blood-brain tumor barrier permeability increase in a rat brain tumor model

scientific article published in December 2003

Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes

scientific article

Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats

scientific article published on June 1, 1995

Adenovirus-mediated p53 gene delivery potentiates the radiation-induced growth inhibition of experimental brain tumors

scientific article published on May 1, 1998

Advances in Imaging: Brain Tumors to Alzheimer's Disease

scholarly article published 1 September 2015

Advances in Retinal Imaging: Retinal Amyloid Imaging

scientific article published in 2020

Age‐related resident memory CD8 T cells link amyloid to NFTs and neurodegeneration in mice and are modulated in AD and MCI blood

scientific article published in December 2020

Alzheimer's Retinopathy: Seeing Disease in the Eyes

scientific article published on 08 September 2020

Alzheimer's disease in the retina: imaging retinal aβ plaques for early diagnosis and therapy assessment

scientific article published on 10 February 2012

Alzheimer's disease pathophysiology in the Retina

scientific article published in July 2024

Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline

scientific article

Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens

scientific article published in August 2009

Antigen-specific age-related memory CD8 T cells induce and track Alzheimer's-like neurodegeneration

scientific article published on 16 July 2024

Antigen-specific age-related memory CD8 T cells induce and track Alzheimer's-like neurodegeneration

scientific article published on 22 January 2024

Antisense inhibition of laminin-8 expression reduces invasion of human gliomas in vitro

scientific article published on October 1, 2003

Association between in-hospital adverse events and mortality for patients with brain tumors

scientific article published on 22 May 2015

Association between laminin-8 and glial tumor grade, recurrence, and patient survival

scientific article

Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.

scientific article published on 24 September 2009

Author Correction: Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy

scientific article published on 30 January 2020

Author Correction: Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy

scientific article published on 26 November 2020

Biopsy versus resection for the management of low-grade gliomas

scientific article

Biopsy versus resection for the management of low-grade gliomas

scientific article (published 2011-09-07)

Biopsy versus resection for the management of low-grade gliomas.

scientific article

Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk

scientific article published on 18 January 2019

Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy

scientific article published on 28 August 2019

Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly(beta-L-malic acid).

scientific article published on 05 June 2007

CD103 Deficiency Promotes Autism (ASD) and Attention-Deficit Hyperactivity Disorder (ADHD) Behavioral Spectra and Reduces Age-Related Cognitive Decline

scientific article published in 2020

Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model

scientific article published on 14 March 2007

Calcium-dependent potassium channels as a target protein for modulation of the blood-brain tumor barrier

scientific article published in June 2003

Cellular delivery of doxorubicin via pH-controlled hydrazone linkage using multifunctional nano vehicle based on poly(β-l-malic acid)

scientific article

Cellular immunity in the treatment of brain tumors

scientific article published in January 2004

Changes in laminin isoforms associated with brain tumor invasion and angiogenesis

scientific article

Characterization of defective CD4-CD8- T cells in murine tumors generated independent of antigen specificity

scientific article published on February 2004

Chemokine CXC receptor 4--mediated glioma tumor tracking by bone marrow--derived neural progenitor/stem cells

scientific article

Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes.

scientific article published on 14 February 2017

Clinical Use of Functional MRI Assessment in Operative Planning for Patient swith Neoplasms Involving Language Areas

scientific article published in 1998

Clinical experience with a high definition exoscope system for surgery of pineal region lesions

scientific article

Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination

scientific article published in August 2004

Coarse particulate matter (PM2.5-10) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains.

scientific article

Color and contrast vision in mouse models of aging and Alzheimer's disease using a novel visual-stimuli four-arm maze

scientific article published on 13 January 2021

Comparative analysis of outcomes following craniotomy and expanded endoscopic endonasal transsphenoidal resection of craniopharyngioma and related tumors: a single-institution study

scientific article published on 11 September 2015

Comparison of survival between cerebellar and supratentorial glioblastoma patients: surveillance, epidemiology, and end results (SEER) analysis

scientific article

Connective tissue growth factor associated with oncogenic activities and drug resistance in glioblastoma multiforme

scientific article

Contralateral functional reorganization of the speech supplementary motor area following neurosurgical tumor resection

scientific article published on 18 May 2018

Critical plasma pentobarbital levels in the treatment of acute ischemic stroke

scientific article published on 01 October 1979

Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme.

scientific article

Curcumin Targeted, Polymalic Acid-Based MRI Contrast Agent for the Detection of Aβ Plaques in Alzheimer's Disease

scientific article published on 2 June 2015

Cyclic GMP-specific phosphodiesterase inhibition and intracarotid bradykinin infusion enhances permeability into brain tumors

scientific article published on March 1, 1998

Cyr61 is overexpressed in gliomas and involved in integrin-linked kinase-mediated Akt and beta-catenin-TCF/Lef signaling pathways

scientific article published in March 2004

Cystic glioblastoma: an evaluation of IDH1 status and prognosis

scientific article published in January 2014

Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy

scientific article

DCVax-Brain and DC vaccines in the treatment of GBM

scientific article published on 01 April 2009

DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors

scientific article

Delayed pentobarbital therapy of acute focal cerebral ischemia

scientific article published on May 1, 1978

Dendritic cell vaccines and immunity in glioma patients

scientific article

Dendritic cell vaccines and obstacles to beneficial immunity in glioma patients

scientific article

Dendritic cell-based immunotherapy for malignant gliomas

scientific article

Desferoxamine (DFO)--mediated iron chelation: rationale for a novel approach to therapy for brain cancer

scientific article published on May 2004

Development of an intracranial ependymoma at the site of a pre-existing cavernous malformation

scientific article

Different effects of KCa and KATP agonists on brain tumor permeability between syngeneic and allogeneic rat models

scientific article published on 21 June 2008

Distinct mechanisms of membrane permeation induced by two polymalic acid copolymers

scientific article published on 9 October 2012

Distinction of brain tissue, low grade and high grade glioma with time-resolved fluorescence spectroscopy

scientific article published in May 2006

Distinctive retinal peri-arteriolar versus peri-venular amyloid plaque distribution correlates with the cognitive performance

scientific article published on 29 February 2024

Do Long-Term Survivor Primary Glioblastoma Patients Harbor IDH1 Mutations?

scientific article

Does 30-day readmission affect long-term outcome among glioblastoma patients?

scientific article

EXTH-59. IMMORTALIZATION OF MOUSE BONE MARROW-DERIVED MACROPHAGES FOR BRAIN TUMOR THERAPY DEVELOPMENT

scientific article published in November 2022

Effect of intravenous eicosapentaenoic acid on cerebral blood flow, edema and brain prostaglandins in ischemic gerbils

scientific article published on October 1, 1984

Effectiveness of radiotherapy for elderly patients with anaplastic gliomas

scientific article

Effects of IL-34 on Macrophage Immunological Profile in Response to Alzheimer's-Related Aβ42 Assemblies

scientific article published on 16 July 2020

Egr1 expression is induced following glatiramer acetate immunotherapy in rodent models of glaucoma and Alzheimer's disease.

scientific article

Enchanced cytokines delivery and intercellular adhesion molecule 1 (lCAM-1) expression in glioma by intracarotid infusion of bradykinin analog, RMP-7

scientific article published on October 1, 1997

Epigenetic derepression of H3K9me3 mitigates Alzheimer-related pathology and improves cognition via immunomodulation and Vgf induction

scientific article published on 18 October 2024

Exploitation of adaptive evolution in glioma treatment

scientific article published on March 2013

Exposure to environmental airborne particulate matter caused wide-ranged transcriptional changes and accelerated Alzheimer's-related pathology: A mouse study

scientific article published in October 2023

Functional recreation of age-related CD8 T cells in young mice identifies drivers of aging- and human-specific tissue pathology

scientific article published on 07 September 2020

Gene expression changes in rat brain after short and long exposures to particulate matter in Los Angeles basin air: Comparison with human brain tumors

scientific article published on 18 May 2013

Generation of neural progenitor cells from whole adult bone marrow.

scientific article published in December 2002

Glatiramer Acetate Immunomodulation: Evidence of Neuroprotection and Cognitive Preservation

scientific article published on 08 May 2022

Glioblastoma induction after radiosurgery for meningioma.

scientific article published in November 2000

Glioblastoma multiforme cells: expression of erythropoietin receptor and response to erythropoietin.

scientific article

Glioma immunotherapy enhancement and CD8-specific sialic acid cleavage by isocitrate dehydrogenase (IDH)-1

scientific article published in June 2023

Glioma stem cell research for the development of immunotherapy

scientific article published on January 2010

Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4

scientific article

HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells

scientific article published on July 2004

Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas

scientific article published on 11 September 2008

High levels of phosphorylated MAP kinase are associated with poor survival among patients with glioblastoma during the temozolomide era

scientific article published on 31 October 2012

High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray

scientific article

Histochemical evaluation of energy metabolism in rat glioma

scientific article published on September 1, 1992

IMCT-12A PHASE 1 TRIAL OF VACCINATION WITH AUTOLOGOUS DENDRITIC CELLS PULSED WITH LYSATE DERIVED FROM AN ALLOGENEIC GLIOBLASTOMA STEM-LIKE CELL LINE FOR PATIENTS WITH NEWLY DIAGNOSED OR RECURRENT GLIOBLASTOMA.

scientific article

IMMU-50. BBB CROSSING NANO-IMMUNOMEDICINE COMBINATION THERAPY TO TREAT BRAIN PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA

scientific article published in November 2020

IMPS-35UNUSUAL TUMOR INFILTRATING LYMPHOCYTES IN DE NOVO GLIOBLASTOMA FOLLOWING PRE-TREATMENT WITH ANTI-PD-L1 THERAPY FOR PRECEDING METASTATIC NSCLC: CASE PRESENTATION WITH DISCUSSION.

scientific article

IT-13IPILIMUMAB FOR RECURRENT HIGH-GRADE GLIOMA: A SINGLE-INSTITUTION CASE SERIES.

scientific article

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

scientific article

Identification of diverse pathological Tau forms in the retina of MCI and AD patients

scientific article published in December 2023

Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina

scientific article published on 10 February 2020

Identification of retinal oligomeric, citrullinated, and other tau isoforms in early and advanced AD and relations to disease status

scientific article published on 9 July 2024

Identification of retinal tau oligomers, citrullinated tau, and other tau isoforms in early and advanced AD and relations to disease status

scientific article published on 16 February 2024

Immunotherapy targeting glioma stem cells--insights and perspectives

scientific article published on 26 December 2011

Imprinting status of DLK1 gene in brain tumors and lymphomas

scientific article published in April 2004

Improving the delivery of therapeutic agents to CNS neoplasms: a clinical review

scientific article

In situ adenoviral interleukin 12 gene transfer confers potent and long-lasting cytotoxic immunity in glioma

scientific article published in January 2002

Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors.

scientific article published in June 2008

Increased endothelial vesicular transport correlates with increased blood-tumor barrier permeability induced by bradykinin and leukotriene C4.

scientific article published in August 2002

Increased opening of blood-tumour barrier by leukotriene C4 is dependent on size of molecules

scientific article published on December 1, 1992

Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2-overexpressing glioma

scientific article published on October 2004

Induction of glioblastoma apoptosis using neural stem cell-mediated delivery of tumor necrosis factor-related apoptosis-inducing ligand

scientific article

Induction of potent antitumor immunity by intratumoral injection of interleukin 23-transduced dendritic cells.

scientific article published on September 2006

Inflammatory leukocytes associated with increased immunosuppression by glioblastoma

scientific article published on July 1, 1992

Infratentorial supracerebellar resection of a pineal tumor using a high definition video exoscope (VITOM®).

scientific article

Inhibition of brain tumor growth by intravenous poly(β- l -malic acid) nanobioconjugate with pH-dependent drug release

scientific article published on October 4, 2010

Inhibition of laminin-8 in vivo using a novel poly(malic acid)-based carrier reduces glioma angiogenesis

scientific article

Inner blood‐retinal barrier alterations associated with vascular amyloidosis in MCI and AD patients

scientific article published in December 2022

Integrated Retinal Amyloid Burden With Retinal Venular Tortuosity Predicts Verbal Memory Impairment

scientific article published on 6 May 2021

Interleukin-23-expressing bone marrow-derived neural stem-like cells exhibit antitumor activity against intracranial glioma.

scientific article published on March 2006

Intra-arterial administration of carboplatin and the blood brain barrier permeabilizing agent, RMP-7: a toxicologic evaluation in swine

scientific article published on January 1, 1998

Intra-arterial carboplatin chemotherapy for brain tumors: a dose escalation study based on cerebral blood flow

scientific article published on November 1, 1997

Intracarotid low dose bradykinin infusion selectively increases tumor permeability through activation of bradykinin B2 receptors in malignant gliomas

scientific article published on May 4, 1998

Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy

scientific article

Intraoperative glioma characterization using time-resolved fluorescence spectroscopy

scientific article published in June 2023

Intratumoral T cell subset ratios and Fas ligand expression on brain tumor endothelium

scientific article

Intratumoral dendritic cell vaccination elicits potent tumoricidal immunity against malignant glioma in rats

scientific article published in March 2003

Intrinsically de-sialylated CD103(+) CD8 T cells mediate beneficial anti-glioma immune responses

scientific article

Isolation of cancer stem cells from adult glioblastoma multiforme

scientific article published on 01 December 2004

KLF6: mutational analysis and effect on cancer cell proliferation.

scientific article published on January 2007

Label-Free Hyperspectral Imaging and Deep-Learning Prediction of Retinal Amyloid β-Protein and Phosphorylated Tau

scientific article published on 4 June 2022

Label-free hyperspectral imaging and deep-learning prediction of retinal amyloid β-protein and phosphorylated tau

Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas

scientific article published in March 2004

Ligands for PPARgamma and RAR cause induction of growth inhibition and apoptosis in human glioblastomas

scientific article published in November 2003

Long-term survival in a child with a central nervous system medulloepithelioma

scientific article

Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era.

scientific article

MRI Virtual Biopsy and Treatment of Brain Metastatic Tumors with Targeted Nanobioconjugates: Nanoclinic in the Brain

scientific article (publication date: 6 May 2015)

Mahaley Clinical Research Award: chemosensitization of glioma through dendritic cell vaccination.

scientific article published on January 2006

Malignant astroblastoma with rhabdoid morphology

scientific article

Manipulation of proliferation and differentiation of human bone marrow-derived neural stem cells in vitro and in vivo

scientific article

Measurement of blood-brain and blood-tumor barrier permeabilities with [14C]-labeled tracers

scientific article published in January 2003

Meningioma transformation to glioblastoma following stereotactic radiosurgery: A case report and review of the literature

scientific article published in 2023

Methylation, expression, and mutation analysis of the cell cycle control genes in human brain tumors

scientific article

Microbial infection and associated inflammasome in the retina of Alzheimer’s disease patients

scientific article published in December 2023

Modifications of the transoral approach to the craniovertebral junction: anatomic study and clinical correlations

scientific article published in March 2008

Modulation of brain tumor capillaries for enhanced drug delivery selectively to brain tumor

scientific article published on May 2004

Molecular and functional analysis of tyrosinase-related protein (TRP)-2 as a cytotoxic T lymphocyte target in patients with malignant glioma

scientific article published on July 2003

Multifunctional Nanopolymers for Blood-Brain Barrier Delivery and Inhibition of Glioblastoma Growth through EGFR/EGFRvIII, c-Myc, and PD-1

scientific article published on 28 October 2021

Multiple resections and survival of recurrent glioblastoma patients in the temozolomide era.

scientific article published on 5 December 2015

NI-49SMART SUCKER: NEXT GENERATION SMART SURGICAL TOOL FOR INTRAOPERATIVE BRAIN TUMOR RESECTION USING TIME RESOLVED LASER INDUCED FLUORESCENCE SPECTROSCOPY

scientific article published in November 2014

NIMG-01. MRI VIRTUAL BIOPSY AND TREATMENT OF PRIMARY OR BRAIN METASTATIC TUMORS WITH TARGETED NANOBIOCONJUGATES

scientific article published in November 2020

NIMG-03FALSE POSITIVE DETECTION OF RESIDUAL TUMOR IN THE IMMEDIATE POSTOPERATIVE PERIOD.

scientific article

Nanobiopolymer for direct targeting and inhibition of EGFR expression in triple negative breast cancer

scientific article

Nanoconjugate Platforms Development Based in Poly(β,L-Malic Acid) Methyl Esters for Tumor Drug Delivery

scientific article published on January 2010

Nanoconjugate based on polymalic acid for tumor targeting

scientific article published on 8 February 2007

Nanoparticles crossing blood–brain barrier need specific design for normal, neurodegenerative or cancerous brain conditions

scientific article published on 7 August 2024

Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: what should be the policy?

scientific article

Nanoprodrugs of NSAIDs Inhibit the Growth of U87-MG Glioma Cells

Nanoprodrugs of NSAIDs: Preparation and Characterization of Flufenamic Acid Nanoprodrugs.

scientific article published on 5 April 2011

Near Infrared Fluorescent Nanoplatform for Targeted Intraoperative Resection and Chemotherapeutic Treatment of Glioblastoma

scientific article published on 17 June 2020

Near-infrared imaging of brain tumors using the Tumor Paint BLZ-100 to achieve near-complete resection of brain tumors

scientific article published on February 2014

Neural stem cells as delivery vehicles

scientific article

Neurosurgery at the crossroads of immunology and nanotechnology. New reality in the COVID-19 pandemic

scientific article published in February 2022

Nitric oxide and cyclic GMP attenuate sensitivity of the blood-tumor barrier permeability to bradykinin

scientific article published on September 1, 1998

Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase

scientific article

Novel MRI Nano-Contrast Agents for Precise Diagnosis of Primary and Metastatic Brain Tumors

scientific article published in December 2020

Novel human malignancy-associated gene (MAG) expressed in various tumors and in some tumor preexisting conditions

scientific article published on October 1, 1998

Ocular indicators of Alzheimer's: exploring disease in the retina

scientific article

Optical Coherence Tomography in Alzheimer's Disease and Other Neurodegenerative Diseases.

scientific article published on 19 December 2017

Osteopontin depletion in macrophages perturbs proteostasis and leads to UCHL1 deficiency and mitochondria-mediated apoptosis

scientific article published on 28 September 2022

Osteopontin depletion in macrophages perturbs proteostasis via regulating UCHL1-UPS axis and mitochondria-mediated apoptosis

scientific article published on 30 May 2023

Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases

scientific article

Overexpression of bradykinin type 2 receptors on glioma cells enhances bradykinin-mediated blood-brain tumor barrier permeability increase

scientific article published in December 2002

Oxidative stimuli-responsive nanoprodrug of camptothecin kills glioblastoma cells

scientific article published on 23 July 2010

P1‐022: RETINAL VASCULAR AMYLOIDOSIS ALONG WITH PERICYTE LOSS IN MCI AND AD PATIENTS

scholarly article

P1‐161: IMMUNOMODULATION: A PATH TO CEREBRAL AND RETINAL HOMEOSTASIS IN AN OLD, LATE‐STAGE MODEL OF ALZHEIMER'S DISEASE

scientific article published in July 2019

P2‐193: EARLY RETINAL AMYLOID‐ASSOCIATED PATHOLOGICAL CHANGES IN MCI AND AD PATIENTS

scholarly article

PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model

scientific article published on 14 July 2008

Parallels between retinal and brain pathology and response to immunotherapy in old, late-stage Alzheimer's disease mouse models

scientific article published on 14 October 2020

Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease

scientific article published on 01 January 2020

Phase 1 Safety, Pharmacokinetics, and Fluorescence Imaging Study of Tozuleristide (BLZ-100) in Adults With Newly Diagnosed or Recurrent Gliomas

scientific article published on 01 October 2019

Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma

scientific article published on 31 July 2012

Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme

scientific article

Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models

scientific article

Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery

scientific article published on April 2008

Polycefin, a new prototype of a multifunctional nanoconjugate based on poly(beta-L-malic acid) for drug delivery

scientific article published on March 2006

Polymalic Acid Tritryptophan Copolymer Interacts with Lipid Membrane Resulting in Membrane Solubilization

scientific article published on 21 May 2017

Polymalic acid chlorotoxin nanoconjugate for near-infrared fluorescence guided resection of glioblastoma multiforme

scientific article published on 23 March 2019

Polymalic acid nanobioconjugate for simultaneous immunostimulation and inhibition of tumor growth in HER2/neu-positive breast cancer

scientific article published on 12 June 2013

Polymalic acid-based nano biopolymers for targeting of multiple tumor markers: an opportunity for personalized medicine?

scientific article

Polymalic acid-based nanobiopolymer provides efficient systemic breast cancer treatment by inhibiting both HER2/neu receptor synthesis and activity

scientific article

Predictors of improved functional outcome following inpatient rehabilitation for patients with traumatic brain injury

scientific article published in July 2016

Preparation and characterization of antioxidant nanospheres from multiple alpha-lipoic acid-containing compounds

scientific article published on 4 February 2009

Prognosis of patients with multifocal glioblastoma: a case-control study

scientific article published on 24 August 2012

Prolonged treatment with biologic agents for malignant glioma: a case study with high dose tamoxifen

scientific article published on October 1, 1997

Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).

scientific article

Proteomics profiling reveals Spp1 deficiency to downregulate UCHL1 in macrophages and to associate with lysosome‐mitochondria mediated apoptotic pathways

scientific article published in December 2021

Quality of surgical care and readmission in elderly glioblastoma patients

scientific article

Quantitative analysis of PMLA nanoconjugate components after backbone cleavage

scientific article published on 16 April 2015

Racial and gender disparities and the role of primary tumor type on inpatient outcomes following craniotomy for brain metastases

scientific article

Reactive oxygen species responsive nanoprodrug to treat intracranial glioblastoma.

scientific article published on 4 April 2013

Real time optical Biopsy: Time-resolved Fluorescence Spectroscopy instrumentation and validation

scientific article

Recent progress in immunotherapy for malignant glioma: treatment strategies and results from clinical trials

scientific article published on May 2004

Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia

scientific article published in 2022

Regulation of blood-brain tumor barrier permeability by calcium-activated potassium channels

scientific article published in June 2002

Response of microglial cells to experimental rat glioma

scientific article published on January 1, 1992

Retinal Amyloid Count And Venular Tortuosity Correlate With Neurocognitive Status (P4-3.002)

scientific article published on 3 May 2022

Retinal Pathological Features and Proteome Signatures of Alzheimer’s

scientific article published on 11 October 2022

Retinal Vascular Tortuosity Correlates with Retinal Amyloid Count: a Cohort Study (892)

scientific article published on 14 April 2020

Retinal Vasculopathy in Alzheimer's Disease

scientific article published in 2021

Retinal Venular Tortuosity Jointly with Retinal Amyloid Burden Correlates with Verbal Memory Loss: A Pilot Study

scientific article published on 28 October 2021

Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease

scientific article published on 17 August 2017

Retinal arterial Aβ deposition is linked with tight junction loss and cerebral amyloid angiopathy in MCI and AD patients

scientific article published in November 2023

Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease

scientific article published on 23 November 2020

Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease

scientific article published on 21 September 2024

Retinal pathological features and proteome signatures of Alzheimer's disease

scientific article published in April 2023

Retinal peri-arteriolar versus peri-venular amyloidosis, hippocampal atrophy, and cognitive impairment: exploratory trial

scientific article published on 28 June 2024

Revolution of Alzheimer Precision Neurology Passageway of Systems Biology and Neurophysiology

scientific article published on 16 March 2018

SCDT-07. BORDER LINE SIZED NANO DRUGS FOR EFFICIENT TARGETING AND DELIVERY THROUGH MULTI BIO BARRIERS

SCDT-39. NANOBIOCONJUGATES CROSSING BBB FOR DELIVERY OF CHECKPOINT INHIBITORS AND ACTIVATION OF LOCAL BRAIN TUMOR IMMUNE SYSTEMS FOR GLIOMA TREATMENT

SCDT-43. BLOCKING OF INTERACTING CK2 AND EGFR PATHWAYS BY TUMOR-TARGETING NANOCONJUGATES INCREASES THERAPEUTIC EFFICACY AGAINST GLIOBLASTOMA MULTIFORME

SURG-19CLINICAL TRANSLATION OF A NOVEL VIDEO IMAGING SYSTEM FOR NEAR-INFRARED FLUORESCENCE GUIDED RESECTION OF BRAIN TUMORS.

scientific article

Sectoral segmentation of retinal amyloid imaging in subjects with cognitive decline

scientific article published on 28 September 2020

Selective blood-tumor barrier disruption by leukotrienes

scientific article published on September 1, 1992

Sensitization of malignant glioma to chemotherapy through dendritic cell vaccination

scientific article

Signature Effects of Vector-Guided Systemic Nano Bioconjugate Delivery Across Blood-Brain Barrier of Normal, Alzheimer’s, and Tumor Mouse Models

scientific article published in 2022

Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme.

scientific article published on 4 November 2016

Single- and Multi-Arm Gadolinium MRI Contrast Agents for Targeted Imaging of Glioblastoma

scientific article published on 01 May 2020

Small Bowel Metastatic Melanoma: An Under-Recognized Complication of Previously Treated Melanoma

scholarly article

Small interference RNA modulation of IL-10 in human monocyte-derived dendritic cells enhances the Th1 response

scientific article published in June 2004

Spatial interplay between synaptic loss, UCH‐L1 deficiency, and pTau accumulation in the retina of MCI and AD patients

scientific article published in December 2023

Spheres isolated from 9L gliosarcoma rat cell line possess chemoresistant and aggressive cancer stem-like cells

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