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List of works by Tatjana Stankovic

A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development

scientific article

A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma

scientific article published on 23 June 2017

A new minimal deleted region at 11q22.3 reveals the importance of interpretation of diminished FISH signals and the choice of probe for ATM deletion screening in chronic lymphocytic leukemia

scientific article published on 28 September 2011

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival.

scientific article published on 3 February 2005

A novel functional assay using etoposide plus nutlin-3a detects and distinguishes between ATM and TP53 mutations in CLL.

scientific article

A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia.

scientific article published on June 1994

A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation

scientific article

ATM Mutations and Phenotypes in Ataxia-Telangiectasia Families in the British Isles: Expression of Mutant ATM and the Risk of Leukemia, Lymphoma, and Breast Cancer ⬇️

scientific article published on February 1, 1998

ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele ⬇️

scientific article published on September 20, 2011

ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.

scientific article

ATM mutations in sporadic lymphoid tumours.

scientific article

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

scientific article published in Nature Communications

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

article

ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells

scientific article published on 12 November 2015

Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy

scientific article published in January 1997

An unrelated cytogenetic karyotype and intra-lineage shift at relapse of an aggressive paediatric B-precursor ALL

scientific article published on 01 November 2002

Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-kappaB survival pathway signaling.

scientific article

Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification

scientific article

Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage

scientific article published on 01 January 2002

BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia.

scientific article

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

scientific article published in Nature

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

scientific article

Clonal diversity of Ig and T-cell receptor gene rearrangements in childhood B-precursor acute lymphoblastic leukaemia.

scientific article

Clonal diversity of Ig and T-cell-receptor gene rearrangements identifies a subset of childhood B-precursor acute lymphoblastic leukemia with increased risk of relapse ⬇️

scientific article published on August 1, 1998

Clonal diversity, measured by heterogeneity of Ig and TCR gene rearrangements, in some acute leukaemias of childhood is associated with a more aggressive disease

scientific article published on 01 January 1995

Construction of a transcription map around the gene for ataxia telangiectasia: identification of at least four novel genes

scientific article

Down-regulation of ATM protein in HRS cells of nodular sclerosis Hodgkin's lymphoma in children occurs in the absence of ATM gene inactivation.

scientific article

Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts

scientific article

Extreme telomere erosion in ATM-mutated and 11q-deleted CLL patients is independent of disease stage

scientific article published on 11 October 2011

Functional modules integrating essential cellular functions are predictive of the response of leukaemia cells to DNA damage.

scientific article published on 17 September 2008

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

article

Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas

article

Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL

scientific article published on 01 February 2020

Irradiation hybrids for human chromosome 11: characterization and use for generating region-specific markers in 11q14-q23.

scientific article published on February 1993

KIBRAgene methylation is associated with unfavorable biological prognostic parameters in chronic lymphocytic leukemia

scientific article published on 01 March 2012

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

scientific article published on 3 July 2008

Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses.

scientific article

Molecular analysis of single colonies reveals a diverse origin of initial clonal proliferation in B-precursor acute lymphoblastic leukemia that can precede the t(12;21) translocation

scientific article published on 01 December 2001

Molecular mechanisms involved in chemoresistance in paediatric acute lymphoblastic leukaemia.

scientific article published on March 2008

Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.

scientific article published on 29 October 2007

Mutations associated with variant phenotypes in ataxia-telangiectasia

scientific article published in August 1996

Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL.

scientific article published on 12 July 2005

Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia.

scientific article

NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma.

scientific article published on 17 September 2016

PALB2 variant status in hematological malignancies – a potential therapeutic target?

scientific article published on 07 January 2019

PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains

scientific article

Pathogenic ATM mutations occur rarely in a subset of multiple myeloma patients.

scientific article published on 28 June 2008

Production and characterization of human proliferative T-cell clones specific for human papillomavirus type 1 E4 protein.

scientific article published on May 1993

RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling

scholarly article

Rapid production of diversity during the progression of a mixed lineage leukaemia

scientific article published on 01 October 1992

Recurrent ATM mutations in T-PLL on diverse haplotypes: no support for their germline origin

scientific article published on 01 March 2001

Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T-->G mutations, showing a less severe phenotype.

scientific article published on 29 May 2001

Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

scientific article published on 09 February 2022

Synergistic Action of Dual IGF1/R and MEK Inhibition Sensitizes Childhood Acute Lymphoblastic Leukaemia (ALL) Cells to Cytotoxic Agents and Involves Down-Regulation of STAT6 and PDAP1.

scientific article published on 12 April 2018

Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway

scientific article published in February 2015

T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice.

scientific article

TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells

scientific article published in July 2015

Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants

scientific article published on 3 April 2015

Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.

scientific article

The ATM tumour suppressor gene is down-regulated in EBV-associated nasopharyngeal carcinoma.

scientific article

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

scientific journal article

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

scientific article

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

scientific article published on 18 August 2014

The impact of SF3B1 mutations in CLL on the DNA-damage response

scientific article

The role of ATM mutations and 11q deletions in disease progression in chronic lymphocytic leukemia.

scientific article

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status

scientific article

USP7 is essential for maintaining Rad18 stability and DNA damage tolerance.

scientific article published on 11 May 2015

ZAP-70 is highly expressed in most cases of childhood pre-B cell acute lymphoblastic leukemia.

scientific article

[Clinical manifestations of neuroblastoma in children and their effect on prognosis]

scientific article published on 01 July 1989

[Glycogenosis IB in an infant]

scientific article published on 01 October 1988

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

scientific article published on 01 August 2001

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