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List of works by Christopher M Hovens

A Phase IIa Randomized Control Trial of VEL015 (Sodium Selenate) in Mild-Moderate Alzheimer's Disease

scientific article published on 22 July 2016

A urinary microRNA signature can predict the presence of bladder urothelial carcinoma in patients undergoing surveillance.

scientific article

AF6/s-afadin is a dual residency protein and localizes to a novel subnuclear compartment.

scientific article published on January 2007

Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice

scientific article

An epitope tagged mammalian/prokaryotic expression vector with positive selection of cloned inserts

scientific article published on 01 September 1997

An in vitro assay of beta-galactosidase from yeast

scientific article published on 01 June 1996

Androgen deprivation therapy promotes an obesity-like microenvironment in periprostatic fat

scientific article published on 01 May 2019

Androgen synthesis in prostate cancer: do all roads lead to Rome?

scientific article published on 8 November 2016

Androstenedione is the preferred androgen source in hormone refractory prostate cancer--response

scientific article published on 01 September 2014

Aurora kinase B is an independent protective factor in superficial bladder tumours with a dysfunctional G1 checkpoint.

scientific article published in July 2008

Bladder cancer biorepositories in the "-omics" era: integrating quality tissue specimens with comprehensive clinical annotation.

scientific article published on 31 May 2013

Canonical androstenedione reduction is the predominant source of signaling androgens in hormone-refractory prostate cancer

scientific article

Cell quiescence correlates with enhanced glioblastoma cell invasion and cytotoxic resistance

scientific article published on 15 December 2018

Circulating endothelial cells as biomarkers of prostate cancer.

scientific article published on August 2008

Comparing nodal versus bony metastatic spread using tumour phylogenies.

scientific article published on 22 September 2016

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Curated microRNAs in urine and blood fail to validate as predictive biomarkers for high-risk prostate cancer

scientific article published on 4 April 2014

Developments in oligometastatic hormone-sensitive prostate cancer

scientific article published on 31 October 2018

Disrupting the Status Quo in Prostate Cancer Diagnosis.

scientific article published on 20 August 2016

Does perineural invasion in a radical prostatectomy specimen predict biochemical recurrence in men with prostate cancer?

scientific article published on May 2015

Early perfusion MRI predicts survival outcome in patients with recurrent glioblastoma treated with bevacizumab and carboplatin

scientific article

Error rates in a clinical data repository: lessons from the transition to electronic data transfer—a descriptive study ⬇️

scientific article published on May 28, 2013

Eve-3: a liver enriched suppressor of Ras/MAPK signaling.

scientific article

Expression of ErbB-1 and 2 in vestibular schwannomas.

scientific article published on 26 October 2007

Expression of ErbB-1 and ErbB-2 in meningioma.

scientific article

Expression of the adaptor protein Tks5 in human cancer: prognostic potential

scientific article published on 4 July 2014

Extraprostatic extension into periprostatic fat is a more important determinant of prostate cancer recurrence than an invasive phenotype.

scientific article published on 29 June 2013

Gene-based urinary biomarkers for bladder cancer: an unfulfilled promise?

scientific article published on 17 October 2013

Genetics of glioblastoma multiforme: mitogenic signaling and cell cycle pathways converge.

scientific article

Glycogen synthase kinase-3β (GSK-3β) and its dysregulation in glioblastoma multiforme.

scientific article published on 12 June 2013

How Subclonal Modeling Is Changing the Metastatic Paradigm

scientific article published on 18 November 2016

Hyperphosphorylated tau is implicated in acquired epilepsy and neuropsychiatric comorbidities

scientific article published on 10 December 2013

Inferring structural variant cancer cell fraction

scientific article published on 05 February 2020

Interfering with cell-survival signalling as a treatment strategy for prostate cancer.

scientific article

Late biochemical recurrence after radical prostatectomy is associated with a slower rate of progression

scientific article published on 19 October 2018

Levels of a subpopulation of platelets, but not circulating endothelial cells, predict early treatment failure in prostate cancer patients after prostatectomy ⬇️

scientific article published on October 9, 2012

Localization of two mouse genes encoding the protein tyrosine kinase receptor-related protein RYK

scientific article

Microscopic assessment of fresh prostate tumour specimens yields significantly increased rates of correctly annotated samples for downstream analysis ⬇️

scientific article published on April 1, 2012

Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management.

scientific article published on 4 August 2017

Molecular Pathways: Targeting DNA Repair Pathway Defects Enriched in Metastasis.

scientific article published on 11 May 2016

Molecular biomarkers for predicting outcomes in urothelial carcinoma of the bladder.

scientific article published on June 2014

Mutagenesis and selection of PDZ domains that bind new protein targets.

scientific article

Obesity suppresses tumor attributable PSA, affecting risk categorization.

scientific article published in May 2018

Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancer.

scientific article published on 20 July 2010

Paraneoplastic syndromes in prostate cancer.

scientific article published on December 2010

Percutaneous image-guided biopsy of prostate cancer metastases yields samples suitable for genomics and personalised oncology

scientific article published on 2 October 2013

Periprostatic fat tissue transcriptome reveals a signature diagnostic for high-risk prostate cancer

scientific article published on 28 March 2018

Perish and publish: Dynamics of biomedical publications by deceased authors

scientific article published in 2022

Positive surgical margins are a risk factor for significant biochemical recurrence only in intermediate-risk disease

scientific article published on 18 January 2012

Preoperative biomarkers of tumour vascularity are elevated in patients with glioblastoma multiforme.

scientific article published on 22 August 2015

Preparation of fluorescent in situ hybridisation probes without the need for optimisation of fragmentation

scientific article published on 27 November 2018

Presence or absence of a positive pathological margin outperforms any other margin‐associated variable in predicting clinically relevant biochemical recurrence in Gleason 7 prostate cancer ⬇️

scientific article published on January 25, 2013

Prostate tumour volume is an independent predictor of early biochemical recurrence in a high risk radical prostatectomy subgroup.

scientific article

Prostate weight is the preferred measure of prostate size in radical prostatectomy cohorts ⬇️

scientific article published on April 1, 2012

Prostatic nerve subtypes independently predict biochemical recurrence in prostate cancer

scientific article published on 13 February 2019

Re-evaluating the biological significance of seminal vesicle invasion (SVI) in locally advanced prostate cancer

scientific article published on 01 December 2012

Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array

scientific article published on 22 January 2014

Reduction in expression of the benign AR transcriptome is a hallmark of localised prostate cancer progression.

scientific article

Repair mechanisms help glioblastoma resist treatment

scientific article

Reply: on the clinical relevance of circulating endothelial cells and platelets in prostate cancer.

scientific article published on 14 February 2013

Routinely reported 'equivocal' lymphovascular invasion in prostatectomy specimens is associated with adverse outcomes.

scientific article published on 19 July 2016

Snail expression is an independent predictor of tumor recurrence in superficial bladder cancers

scientific article published on 22 January 2009

Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury

scientific article published on 13 March 2015

Sodium selenate retards epileptogenesis in acquired epilepsy models reversing changes in protein phosphatase 2A and hyperphosphorylated tau.

scientific article published on 11 June 2016

Sodium selenate, a protein phosphatase 2A activator, mitigates hyperphosphorylated tau and improves repeated mild traumatic brain injury outcomes.

scientific article published on 6 May 2016

Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease

scientific article published on 01 January 2019

Target Acquired: Progress and Promise of Targeted Therapeutics in the Treatment of Prostate Cancer.

scientific article published on January 2015

Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo ⬇️

scientific article published on July 2, 2012

Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models

scientific article

Targeting malignant glioma survival signalling to improve clinical outcomes.

scientific article published on February 2007

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The ability of prostate-specific antigen (PSA) density to predict an upgrade in Gleason score between initial prostate biopsy and prostatectomy diminishes with increasing tumour grade due to reduced PSA secretion per unit tumour volume

scientific article published on 15 November 2011

The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family.

scientific article

The tumour suppressor protein NF2/merlin: the puzzle continues.

scientific article

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer.

scientific article

Tumor vascularity in prostate cancer: an update on circulating endothelial cells and platelets as noninvasive biomarkers.

scientific article published on December 2013

Two versatile eukaryotic vectors permitting epitope tagging, radiolabelling and nuclear localisation of expressed proteins

scientific article published on 01 February 1996

Underestimation of Gleason score at prostate biopsy reflects sampling error in lower volume tumours.

scientific article

Upgrade in Gleason score between prostate biopsies and pathology following radical prostatectomy significantly impacts upon the risk of biochemical recurrence

scientific article published on 28 March 2011

Useful Vectors for the Two-Hybrid System in Mammalian Cells ⬇️

scientific article published on September 1, 1997

VEGF polymorphisms are associated with an increasing risk of developing renal cell carcinoma

scientific article published on 17 August 2010

What Is Oligometastatic Prostate Cancer?

scientific article published on 12 January 2019

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