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List of works by Byoung Chul Cho

A Case of ALK-Rearranged Adenocarcinoma with Small Cell Carcinoma-Like Transformation and Resistance to Crizotinib.

scientific article published on 29 December 2015

A multicenter phase II study of sorafenib in combination with erlotinib in patients with advanced non-small cell lung cancer (KCSG-0806).

scientific article

A multicenter, phase II trial of everolimus in locally advanced or metastatic thyroid cancer of all histologic subtypes

scientific article published on 19 September 2013

A phase Ib study of the combination of afatinib and ruxolitinib in EGFR mutant NSCLC with progression on EGFR-TKIs

scientific article published on 28 May 2019

A prospective phase II trial of S-1 and cisplatin-based chemoradiotherapy for locoregionally advanced esophageal cancer

scientific article published on 22 February 2014

A randomized phase II trial of ERCC1 and RRM1 mRNA expression-based chemotherapy versus docetaxel/carboplatin in advanced non-small cell lung cancer

scientific article published on 25 January 2016

A randomized, phase II study of gefitinib alone versus nimotuzumab plus gefitinib after platinum-based chemotherapy in advanced non-small cell lung cancer (KCSG LU12-01).

scientific article

A single-tube multiplexed assay for detecting ALK, ROS1, and RET fusions in lung cancer.

scientific article

ASCEND-8: A Randomized Phase 1 Study of Ceritinib, 450 mg or 600 mg, Taken with a Low-Fat Meal versus 750 mg in Fasted State in Patients with Anaplastic Lymphoma Kinase (ALK)-Rearranged Metastatic Non-Small Cell Lung Cancer (NSCLC).

scientific article published on 17 July 2017

Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M.

scientific article

Acquired resistance to EGFR targeted therapy in non-small cell lung cancer: Mechanisms and therapeutic strategies.

scientific article published on 20 February 2018

Acquired resistance to cetuximab is mediated by increased PTEN instability and leads cross-resistance to gefitinib in HCC827 NSCLC cells.

scientific article

Activating mutations within the EGFR kinase domain: a molecular predictor of disease-free survival in resected pulmonary adenocarcinoma.

scientific article published on 11 June 2009

Activation of the Met kinase confers acquired drug resistance in FGFR-targeted lung cancer therapy

scientific article

Activity and safety of AZD3759 in EGFR-mutant non-small-cell lung cancer with CNS metastases (BLOOM): a phase 1, open-label, dose-escalation and dose-expansion study

scientific article published on 17 October 2017

An open label, multicenter, phase II study of dovitinib in advanced thyroid cancer.

scientific article published on 9 June 2015

Architectural patterns of p16 immunohistochemical expression associated with cancer immunity and prognosis of head and neck squamous cell carcinoma

scientific article published on 4 October 2017

Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in advanced squamous cell carcinoma of the head and neck: results from a phase I cohort

scientific article published on 01 July 2020

Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus-associated malignancies

scientific article published on 01 December 2020

Cabazitaxel Versus Topotecan in Patients with Small-Cell Lung Cancer with Progressive Disease During or After First-Line Platinum-Based Chemotherapy.

scientific article

Cancer in patients on chronic dialysis in Korea.

scientific article published on 28 January 2009

Capecitabine and doxorubicin combination chemotherapy as salvage therapy in pretreated advanced gastric cancer.

scientific article

Cetuximab rescue a patient with non-small cell lung cancer from rapid disease progression during chemotherapy

scientific article published on 01 January 2007

Characteristics and outcome of ROS1-Positive Non-Small Cell Lung Cancer Patients in Routine Clinical Practice.

scientific article

Characterization of head and neck squamous cell carcinoma arising in young patients: Particular focus on molecular alteration and tumor immunity

scientific article published on 10 December 2018

Clinical and prognostic implications of ALK and ROS1 rearrangements in never-smokers with surgically resected lung adenocarcinoma

scientific article published on 14 January 2014

Clinical course of stage IV invasive mucinous adenocarcinoma of the lung.

scientific article published on 6 November 2016

Clinicopathological and prognostic significance of programmed cell death ligand-1 expression in lung adenocarcinoma and its relationship with p53 status.

scientific article

Co-clinical trials demonstrate predictive biomarkers for dovitinib, an FGFR inhibitor, in lung squamous cell carcinoma.

scientific article

Combination of topotecan and etoposide as a salvage treatment for patients with recurrent small cell lung cancer following irinotecan and platinum first-line chemotherapy.

scientific article

Comprehensive analyses of immunodynamics and immunoreactivity in response to treatment in ALK-positive non-small-cell lung cancer

scientific article published on 01 July 2020

Comprehensive analysis of the characteristics and treatment outcomes of patients with non-small cell lung cancer treated with anti-PD-1 therapy in real-world practice

scientific article published on 25 March 2019

Concordance of programmed death-ligand 1 expression between primary and metastatic non-small cell lung cancer by immunohistochemistry and RNA in situ hybridization.

scientific article

Design and Rationale for a Phase III, Randomized, Placebo-controlled Trial of Durvalumab With or Without Tremelimumab After Concurrent Chemoradiotherapy for Patients With Limited-stage Small-cell Lung Cancer: The ADRIATIC Study

scientific article published on 28 December 2019

Detection of activating and acquired resistant mutation in plasma from EGFR-mutated NSCLC patients by peptide nucleic acid (PNA) clamping-assisted fluorescence melting curve analysis

scientific article published on 10 May 2017

Distinct clinical features and outcomes in never-smokers with nonsmall cell lung cancer who harbor EGFR or KRAS mutations or ALK rearrangement.

scientific article

Dose-Response Relationship between Radiation Dose and Loco-regional Control in Patients with Stage II-III Esophageal Cancer Treated with Definitive Chemoradiotherapy.

scientific article published on 6 October 2016

Dual-targeting of EGFR and Neuropilin-1 attenuates resistance to EGFR-targeted antibody therapy in KRAS-mutant non-small cell lung cancer

scientific article published on 12 September 2019

Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study.

scientific article published on 12 March 2018

Dynamic changes in PD-L1 expression and CD8+ T cell infiltration in non-small cell lung cancer following chemoradiation therapy

scientific article published on 01 August 2019

EGFR polymorphism as a predictor of clinical outcome in advanced lung cancer patients treated with EGFR-TKI.

scientific article

ER2, a novel human anti-EGFR monoclonal antibody inhibit tumor activity in non-small cell lung cancer models.

scientific article published on 27 February 2016

ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma

scientific article published on 25 September 2017

Efficacy and Toxicity of Belotecan for Relapsed or Refractory Small Cell Lung Cancer Patients ⬇️

scientific article published on April 1, 2012

Efficacy and safety of dovitinib in pretreated patients with advanced squamous non-small cell lung cancer with FGFR1 amplification: A single-arm, phase 2 study.

scientific article published on 17 June 2016

Efficacy and safety of vinorelbine plus cisplatin chemotherapy for patients with recurrent and/or metastatic salivary gland cancer of the head and neck

scientific article published on 16 October 2017

Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, phase 3 trial

scientific article published on 27 April 2016

Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice ⬇️

scientific article published on July 6, 2012

Elevated serum C-reactive protein as a prognostic marker in small cell lung cancer

scientific article published on January 2012

Enhancer remodeling and microRNA alterations are associated with acquired resistance to ALK inhibitors.

scientific article published on 18 April 2018

Establishment of a Conditional Transgenic Mouse Model Recapitulating EML4-ALK-Positive Human Non-Small Cell Lung Cancer.

scientific article published on 8 November 2016

Establishment of a platform of non-small-cell lung cancer patient-derived xenografts with clinical and genomic annotation

scientific article published on 11 August 2018

Ethnic differences in survival outcome in patients with advanced stage non-small cell lung cancer: results of a meta-analysis of randomized controlled trials.

scientific article published on June 2011

Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck

scientific article published on 21 January 2016

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer.

scientific article

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma.

scientific article

First-line systemic treatment of advanced stage non-small-cell lung cancer in Asia: consensus statement from the Asian Oncology Summit 2009.

scientific article

Frequent central nervous system failure after clinical benefit with epidermal growth factor receptor tyrosine kinase inhibitors in Korean patients with nonsmall-cell lung cancer.

scientific article published on March 2010

Genomic profiling of lung adenocarcinoma patients reveals therapeutic targets and confers clinical benefit when standard molecular testing is negative

scientific article published on 16 March 2016

Glycolysis inhibition sensitizes non-small cell lung cancer with T790M mutation to irreversible EGFR inhibitors via translational suppression of Mcl-1 by AMPK activation.

scientific article published on 24 July 2013

High CD3 and ICOS and low TIM-3 expression predict favourable survival in resected oesophageal squamous cell carcinoma

scientific article published on 27 December 2019

High EGFR gene copy number and skin rash as predictive markers for EGFR tyrosine kinase inhibitors in patients with advanced squamous cell lung carcinoma.

scientific article

Hyperprogressive disease during PD-1/PD-L1 blockade in patients with non-small-cell lung cancer

scientific article published on 01 July 2019

Identification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers

scientific article

Immune checkpoint inhibitors in epidermal growth factor receptor mutant non-small cell lung cancer: Current controversies and future directions.

scientific article

Immunotherapy in the treatment of non-small cell lung cancer

scientific article

Impact of Tumor Purity on Immune Gene Expression and Clustering Analyses across Multiple Cancer Types.

scientific article published on 15 November 2017

Impact of a planned dose interruption of dacomitinib in the treatment of advanced non-small-cell lung cancer (ARCHER 1042).

scientific article published on February 2017

Impact of cigarette smoking on response to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors in lung adenocarcinoma with activating EGFR mutations.

scientific article published on 3 February 2014

Impact of environmental tobacco smoke on the incidence of mutations in epidermal growth factor receptor gene in never-smoker patients with non-small-cell lung cancer.

scientific article published on 14 December 2009

Indoor radon exposure increases tumor mutation burden in never-smoker patients with lung adenocarcinoma

scientific article published on 03 April 2019

Induction docetaxel and S-1 followed by concomitant radiotherapy with low-dose daily cisplatin in locally advanced head and neck carcinoma.

scientific article published on 18 February 2016

Lack of ROS1 Gene Rearrangement in Glioblastoma Multiforme

scientific article published on 14 September 2015

Lung cancer in never smokers: change of a mindset in the molecular era.

scientific article published on 26 January 2011

Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors.

scientific article published in January 2018

Molecular Diagnostic Assays and Clinicopathologic Implications of MET Exon 14 Skipping Mutation in Non-small-cell Lung Cancer

scientific article published on 11 October 2018

Molecular characterization of lung adenocarcinoma from Korean patients using next generation sequencing

scientific article published on 25 November 2019

Mouse-human co-clinical trials demonstrate superior anti-tumour effects of buparlisib (BKM120) and cetuximab combination in squamous cell carcinoma of head and neck

scientific article published on 23 September 2020

Multiple target loci assembly sequencing (mTAS) ⬇️

scientific article published on April 16, 2011

Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance.

scientific article

Neoadjuvant therapy for thymic neoplasms reduces tumor volume per 3D-reconstructed images but does not improve the complete resection rate

scientific article published on 26 March 2019

Next-generation epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor -mutant non-small cell lung cancer

scientific article published on 08 January 2016

Next-generation sequencing reveals novel resistance mechanisms and molecular heterogeneity in EGFR-mutant non-small cell lung cancer with acquired resistance to EGFR-TKIs

scientific article published on 12 September 2017

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus.

scientific article published on 07 February 2016

Nivolumab in NSCLC: latest evidence and clinical potential

scientific article

Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial

scientific article published on 30 September 2019

Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are sensitive to MEK/PI3K inhibition or MEK/CDK4/6 inhibition.

scientific article published on 16 January 2017

Optimal Adjuvant Treatment for Curatively Resected Thoracic Esophageal Squamous Cell Carcinoma: A Radiotherapy Perspective

scientific article published on 23 June 2016

Optimal dose and volume for postoperative radiotherapy in brain oligometastases from lung cancer: a retrospective study

scientific article

PD-L1 expression on immune cells, but not on tumor cells, is a favorable prognostic factor for head and neck cancer patients.

scientific article published on 14 November 2016

PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma.

scientific article published on 15 April 2016

Patient-Derived Cells to Guide Targeted Therapy for Advanced Lung Adenocarcinoma

scientific article published on 27 December 2019

Patient-reported outcomes from FLAURA: Osimertinib versus erlotinib or gefitinib in patients with EGFR-mutated advanced non-small-cell lung cancer

scientific article published on 12 December 2019

Patient-reported outcomes with durvalumab after chemoradiotherapy in stage III, unresectable non-small-cell lung cancer (PACIFIC): a randomised, controlled, phase 3 study

scientific article published on 07 October 2019

Personalized therapy on the horizon for squamous cell carcinoma of the lung.

scientific article published on 13 March 2013

Pharmacogenetic analysis of advanced non-small-cell lung cancer patients treated with first-line paclitaxel and carboplatin chemotherapy

scientific article

Pharmacogenomic assessment of outcomes of pemetrexed-treated patients with adenocarcinoma of the lung.

scientific article published on July 2013

Phase 2 study of dovitinib in patients with metastatic or unresectable adenoid cystic carcinoma.

scientific article published on 22 April 2015

Phase 2 study of intermittent pulse dacomitinib in patients with advanced non-small cell lung cancers.

scientific article published on 23 August 2017

Phase II clinical and exploratory biomarker study of dacomitinib in patients with recurrent and/or metastatic squamous cell carcinoma of head and neck

scientific article published on 25 November 2014

Phase II study of Afatinib as third-line treatment for patients in Korea with stage IIIB/IV non-small cell lung cancer harboring wild-type EGFR

scientific article

Phase II study of cisplatin with irinotecan as induction chemotherapy followed by chemoradiotherapy for unresectable stage III non-small cell lung cancer

scientific article published on 01 August 2012

Phase II study of erlotinib in advanced non-small-cell lung cancer after failure of gefitinib.

scientific article published in June 2007

Phase Ib/II study of the pan-cyclin-dependent kinase inhibitor roniciclib in combination with chemotherapy in patients with extensive-disease small-cell lung cancer

scientific article published on 27 April 2018

Prediction for response duration to epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR mutated never smoker lung adenocarcinoma.

scientific article

Predictive factors for the development of diabetes in cancer patients treated with phosphatidylinositol 3-kinase inhibitors

scientific article published on 27 June 2019

Predictive factors of early distant brain failure after gamma knife radiosurgery alone in patients with brain metastases of non-small-cell lung cancer

scientific article published on 10 January 2017

Preoperative C-reactive protein levels are associated with tumor size and lymphovascular invasion in resected non-small cell lung cancer.

scientific article published on 2 June 2008

Primary idiopathic chylopericardium associated with cervicomediastinal cystic hygroma.

scientific article

Prognostic and predictive value of CEA and CYFRA 21-1 levels in advanced non-small cell lung cancer patients treated with gefitinib or erlotinib

scientific article

Prognostic factors in small cell lung cancer: a new prognostic index in Korean patients.

scientific article published in January 2010

Prognostic impact of resection margin involvement after extended (D2/D3) gastrectomy for advanced gastric cancer: a 15-year experience at a single institute

scientific article published on 01 May 2007

Randomized controlled trial of standardized education and telemonitoring for pain in outpatients with advanced solid tumors ⬇️

scientific article published on January 23, 2013

Randomized phase II study comparing weekly docetaxel-cisplatin vs. gemcitabine-cisplatin in elderly or poor performance status patients with advanced non-small cell lung cancer.

scientific article

Rare Incidence of ROS1 Rearrangement in Cholangiocarcinoma.

scientific article published on 27 April 2016

Real-World Analysis of the Efficacy of Rebiopsy and EGFR Mutation Test of Tissue and Plasma Samples in Drug-Resistant Non-Small Cell Lung Cancer

scientific article published on 01 June 2019

Reduced expression of EI24 confers resistance to gefitinib through IGF-1R signaling in PC9 NSCLC cells.

scientific article published on 2 September 2015

Role of FGF receptors as an emerging therapeutic target in lung squamous cell carcinoma.

scientific article published on March 2013

Safety and efficacy of dacomitinib in korean patients with KRAS wild-type advanced non-small-cell lung cancer refractory to chemotherapy and erlotinib or gefitinib: a phase I/II trial.

scientific article published on October 2014

Screening of ROS1 rearrangements in lung adenocarcinoma by immunohistochemistry and comparison with ALK rearrangements

scientific article

Significance of immune checkpoint proteins in EGFR-mutant non-small cell lung cancer

scientific article published on 15 January 2017

Targeting YAP to overcome acquired resistance to ALK inhibitors in ALK-rearranged lung cancer

scientific article published on 21 October 2019

The Clinical Usefulness of (18)F-Fluorodeoxyglucose Positron Emission Tomography (PET) to Predict Oncologic Outcomes and PET-Based Radiotherapeutic Considerations in Locally Advanced Nasopharyngeal Carcinoma

scientific article published on 11 December 2015

The Ratio of Peripheral Regulatory T Cells to Lox-1 PMN-MDSC Predicts the Early Response to Anti-PD-1 Therapy in Non-Small Cell Lung Cancer Patients

scientific article published on 01 January 2019

The combination of capecitabine and irinotecan in treating 5-Fluorouracil- and Oxaliplatin-pretreated metastatic colorectal cancer

scientific article published on 21 March 2007

The efficacy and toxicity of S-1 and cisplatin as first-line chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma

scientific article published on 07 August 2012

The frequency and impact of FGFR1 amplification on clinical outcomes in Korean patients with small cell lung cancer.

scientific article published on 09 March 2015

The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma

scientific article published on July 2013

The impact of dermatological toxicities of anti-cancer therapy on the dermatological quality of life of cancer patients.

scientific article published on 13 February 2012

The number of residual metastatic lymph nodes following neoadjuvant chemotherapy predicts survival in patients with stage III NSCLC.

scientific article published on 26 December 2007

The regulation of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase by autophagy in low-glycolytic hepatocellular carcinoma cells

scientific article published on 30 May 2015

The role of monoclonal antibody in combination with first-line chemotherapy in Asian patients with advanced non-small cell lung cancer

scientific article

Thoracoscopic Lobectomy Is Associated With Superior Compliance With Adjuvant Chemotherapy in Lung Cancer ⬇️

scientific article published on February 1, 2011

Treatment of epidermal growth factor receptor inhibitor-induced acneiform eruption with topical recombinant human epidermal growth factor.

scientific article published on 21 September 2012

Treatment of the elderly when cure is the goal: the influence of age on treatment selection and efficacy for stage III non-small cell lung cancer.

scientific article published on March 2011

Treatment options for EGFR mutant NSCLC with CNS involvement-Can patients BLOOM with the use of next generation EGFR TKIs?

scientific article

Tumor MET expression profile predicts the outcome of non-small cell lung cancer patients receiving epidermal growth factor receptor tyrosine kinase inhibitors.

scientific article

Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors.

scientific article

Updated Efficacy and Safety Data and Impact of the EML4-ALK Fusion Variant on the Efficacy of Alectinib in Untreated ALK-Positive Advanced Non-Small Cell Lung Cancer in the Global Phase III ALEX Study

scientific article published on 20 March 2019

Validation of ALK/ROS1 Dual Break Apart FISH Probe probe in non-small-cell lung cancer

scientific article published on 12 July 2017

Weekly 5-fluorouracil plus cisplatin for concurrent chemoradiotherapy in patients with locally advanced head and neck cancer.

scientific article published in February 2010

YH25448, an Irreversible EGFR-TKI with Potent Intracranial Activity in EGFR Mutant Non-Small Cell Lung Cancer

scientific article published on 22 January 2019

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