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List of works by Scott E. Graham

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Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells.

scientific article published on 8 July 2015
Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!

scientific article
Photoperiodic regulation of cellular retinol binding protein, CRBP1 [corrected] and nestin in tanycytes of the third ventricle ependymal layer of the Siberian hamster.

scientific article published in December 2006
TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function.

scientific article published on 11 February 2016
Neuromedin U and Neuromedin U receptor-2 expression in the mouse and rat hypothalamus: effects of nutritional status.

scientific article published on December 2003
Application of xCELLigence RTCA Biosensor Technology for Revealing the Profile and Window of Drug Responsiveness in Real Time.

scientific article
Exposure to inflammatory cytokines IL-1β and TNFα induces compromise and death of astrocytes; implications for chronic neuroinflammation.

scientific article
Real-time profiling of NK cell killing of human astrocytes using xCELLigence technology

scientific article
Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.

scientific article
Detailed analysis of inflammatory and neuromodulatory cytokine secretion from human NT2 astrocytes using multiplex bead array.

scientific article published on 10 September 2011
Cannabinoid Receptors: A brief history and what not

scientific article
Detailed characterisation of CB2 receptor protein expression in peripheral blood immune cells from healthy human volunteers using flow cytometry

scientific article published in January 2010
Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: implications for therapeutics

scientific article published on 23 June 2010
Isolation of highly enriched primary human microglia for functional studies

scientific article
The inflammasome pathway is amplified and perpetuated in an autocrine manner through connexin43 hemichannel mediated ATP release

scientific article published on 17 November 2017
Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway.

scientific article published on 24 July 2006
oPer1 is an early response gene under photoperiodic regulation in the ovine pars tuberalis.

scientific article
An anti-inflammatory role for C/EBPδ in human brain pericytes

scientific article published on 13 July 2015
Adult human glia, pericytes and meningeal fibroblasts respond similarly to IFNy but not to TGFβ1 or M-CSF.

scientific article
Patterning and detailed study of human hNT astrocytes on parylene-C/silicon dioxide substrates to the single cell level

scientific article published on September 2011
Cultured pericytes from human brain show phenotypic and functional differences associated with differential CD90 expression.

scientific article published on 24 May 2016
Characterization of NTera2/D1 cells as a model system for the investigation of cannabinoid function in human neurons and astrocytes

scientific article published on 14 June 2011
Evidence for the biosynthesis of a prolactin-releasing factor from the ovine pars tuberalis, which is distinct from thyrotropin-releasing hormone

scientific article published in December 2002
First human hNT neurons patterned on parylene-C/silicon dioxide substrates: Combining an accessible cell line and robust patterning technology for the study of the pathological adult human brain.

scientific article published on 7 October 2010
M1 Muscarinic Receptor Activation Mediates Cell Death in M1-HEK293 Cells

scientific article published on September 2, 2013
Enrichment of differentiated hNT neurons and subsequent analysis using flow-cytometry and xCELLigence sensing

scientific article published on 14 February 2014
Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier

scientific article
Sensitive and accurate quantification of human leukocyte migration using high-content Discovery-1 imaging system and ATPlite assay.

scientific article published in December 2011
Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors

scientific article published on 27 January 2016
Interferon-γ blocks signalling through PDGFRβ in human brain pericytes

scientific article published on 21 September 2016
ECIS technology reveals that monocytes isolated by CD14+ve selection mediate greater loss of BBB integrity than untouched monocytes, which occurs to a greater extent with IL-1β activated endothelium in comparison to TNFα.

scientific article published on 21 July 2017
The functional and inflammatory response of brain endothelial cells to Toll-Like Receptor agonists

scientific article published on 4 July 2018
Patterning of functional human astrocytes onto parylene-C/SiO2 substrates for the study of Ca2+ dynamics in astrocytic networks.

scientific article published on 9 February 2018
Human astrocytic grid networks patterned in parylene-C inlayed SiO2 trenches.

scientific article
Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products

scientific article published on 21 September 2017
Plasmin and regulators of plasmin activity control the migratory capacity and adhesion of human T cells and dendritic cells by regulating cleavage of the chemokine CCL21.

scientific article published on 15 June 2016
A Cell Derived Active Contour (CDAC) method for robust tracking in low frame rate, low contrast phase microscopy - an example: the human hNT astrocyte.

scientific article
The Importance of Multifrequency Impedance Sensing of Endothelial Barrier Formation Using ECIS Technology for the Generation of a Strong and Durable Paracellular Barrier

scientific article published on 04 July 2018
Infra-red laser ablative micromachining of parylene-C on SiO2 substrates for rapid prototyping, high yield, human neuronal cell patterning.

scientific article
Selective PEGylation of Parylene-C/SiO2 Substrates for Improved Astrocyte Cell Patterning.

scientific article published on 9 February 2018
Real-Time Measurement of Melanoma Cell-Mediated Human Brain Endothelial Barrier Disruption Using Electric Cell-Substrate Impedance Sensing Technology

scientific article published on 15 April 2019
Is the Cannabinoid CB2 Receptor a Major Regulator of the Neuroinflammatory Axis of the Neurovascular Unit in Humans?

scientific article published on 12 June 2017
Cannabinoid Receptor 2 (CB2) Signals via G-alpha-s and Induces IL-6 and IL-10 Cytokine Secretion in Human Primary Leukocytes

scientific article published on 01 October 2019
Improving active contour methods for tracking endothelial cells by the removal of low-confidence edge segments.

scientific article published on January 2012
First human hNT astrocytes patterned to single cell resolution on parylene-C/silicon dioxide substrates

scientific article published on January 2011
Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers.

scientific article published on 27 October 2017
Cannabinoid Receptor 2 (CB2) Signals via G-alpha-s and Induces IL-6 and IL-10 Cytokine Secretion in Human Primary Leukocytes

Investigation of the Ca2+ response of human hNT astrocytes to laser removal of cellular processes

scientific article
Low cost, patterning of human hNT brain cells on parylene-C with UV & IR laser machining.

scientific article
Nanosecond Laser Stimulation in an Organized Grid Network of Human Astrocytes

scientific article published on 01 July 2020

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