List of works - Kate Carroll

'Omics' of natural products and redox biology

scientific article published on 01 February 2011

3‘-Phosphoadenosine-5‘-phosphosulfate Reductase in Complex with Thioredoxin: A Structural Snapshot in the Catalytic Cycle † , ‡

scientific article

A Chemical Approach for the Detection of Protein Sulfinylation.

scientific article published on 17 June 2015

A periplasmic reducing system protects single cysteine residues from oxidation

scientific article published in November 2009

A universal entropy-driven mechanism for thioredoxin-target recognition

scientific article published on 15 June 2015

Activity of the tetrapyrrole regulator CrtJ is controlled by oxidation of a redox active cysteine located in the DNA binding domain.

scientific article

Activity-Based Sensing for Site-Specific Proteomic Analysis of Cysteine Oxidation

scientific article published on 23 December 2019

An immunochemical approach to detect oxidized protein tyrosine phosphatases using a selective C-nucleophile tag

scientific article published on 13 January 2016

Call for Papers for the Special Issue on Natural Products in Redox Toxicology

scientific article published on 01 November 2020

Challenges in enzyme mechanism and energetics

scientific article (publication date: 2003)

Chemical approaches to discovery and study of sources and targets of hydrogen peroxide redox signaling through NADPH oxidase proteins

scientific article published on January 2015

Chemical biology approaches to study protein cysteine sulfenylation.

scientific article published on February 2014

Chemical proteomics reveals new targets of cysteine sulfinic acid reductase

scientific article published on 03 September 2018

Chemoselective ligation of sulfinic acids with aryl-nitroso compounds.

scientific article published on 29 May 2012

Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from <i>Mycobacterium tuberculosis</i>

scientific article published on 17 May 2021

Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery

scientific article

DYn-2 Based Identification of Arabidopsis Sulfenomes.

scientific article published on 18 February 2015

Design, synthesis and evaluation of Fe-S targeted adenosine 5'-phosphosulfate reductase inhibitors.

scientific article

Detection of protein S-sulfhydration by a tag-switch technique.

scientific article published on 29 November 2013

Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks

scientific article published on 25 November 2019

Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles

scientific article

Efficient microwave-assisted solid phase coupling of nucleosides, small library generation and mild conditions for release of nucleoside derivatives

scientific article

Empirical entropic contributions in computational docking: evaluation in APS reductase complexes.

scientific article

Expanding the functional diversity of proteins through cysteine oxidation.

scientific article published on 17 September 2008

Facile synthesis and biological evaluation of a cell-permeable probe to detect redox-regulated proteins.

scientific article published on 24 November 2008

First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis

scientific article

Functional Site Discovery in a Sulfur Metabolism Enzyme by Using Directed Evolution.

scientific article published on 13 July 2016

Geometric and electrostatic study of the [4Fe-4S] cluster of adenosine-5'-phosphosulfate reductase from broken symmetry density functional calculations and extended X-ray absorption fine structure spectroscopy.

scientific article published on 16 June 2011

Global, in situ, site-specific analysis of protein S-sulfenylation

scientific article

Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase.

scientific article published on September 2009

Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates

scientific article

Investigation of the iron-sulfur cluster in Mycobacterium tuberculosis APS reductase: implications for substrate binding and catalysis

scientific journal article

Iron-sulfur cluster engineering provides insight into the evolution of substrate specificity among sulfonucleotide reductases.

scientific article published on 9 November 2011

Isotope-coded chemical reporter and acid-cleavable affinity reagents for monitoring protein sulfenic acids

scientific article published on 03 May 2011

Light-Mediated Sulfenic Acid Generation from Photocaged Cysteine Sulfoxide

scientific article

Metabolite imaging: knock, nox-ROS there?

scientific article published on 01 February 2011

Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase

scientific article published on July 2016

Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice

scientific article published in Nature Communications

New targets and inhibitors of mycobacterial sulfur metabolism.

scientific article

Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity.

scientific article

Persulfide reactivity in the detection of protein s-sulfhydration.

scientific article published on 12 April 2013

Probing the Tetrahymena group I ribozyme reaction in both directions.

scientific article published in September 2002

Profiling protein thiol oxidation in tumor cells using sulfenic acid-specific antibodies.

scholarly article

Profiling the Reactivity of Cyclic C-Nucleophiles towards Electrophilic Sulfur in Cysteine Sulfenic Acid

scientific article published on 7 October 2015

Proteome-Wide Analysis of Cysteine S-Sulfenylation Using a Benzothiazine-Based Probe

scientific article published on 12 October 2018

Proteomic analysis of peptides tagged with dimedone and related probes

scientific article published on April 2014

Quantification of protein sulfenic acid modifications using isotope-coded dimedone and iododimedone

scientific article published on 05 January 2011

Rab9 GTPase regulates late endosome size and requires effector interaction for its stability

scientific article

Rational design of reversible and irreversible cysteine sulfenic acid-targeted linear C-nucleophiles.

scientific article published on February 2016

Reactivity, Selectivity, and Stability in Sulfenic Acid Detection: A Comparative Study of Nucleophilic and Electrophilic Probes.

scientific article published on 28 April 2016

Redox Pathways in Chemical Toxicology

scientific article published on 01 March 2019

Redox-based probes as tools to monitor oxidized protein tyrosine phosphatases in living cells

scientific article

Redox-based probes for protein tyrosine phosphatases

scientific article published on 18 April 2011

Reengineering redox sensitive GFP to measure mycothiol redox potential of Mycobacterium tuberculosis during infection

scientific article

RegB kinase activity is repressed by oxidative formation of cysteine sulfenic acid.

scientific article published on 10 January 2013

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

scientific article

Site-Specific Proteomic Mapping Identifies Selectively Modified Regulatory Cysteine Residues in Functionally Distinct Protein Networks

scientific article published on 9 July 2015

Site-specific mapping and quantification of protein S-sulphenylation in cells.

scientific article

Spectroscopic studies on the [4Fe-4S] cluster in adenosine 5'-phosphosulfate reductase from Mycobacterium tuberculosis.

scientific article

Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase.

scientific article published on September 2006

Sulfenic acid chemistry, detection and cellular lifetime

scientific article (publication date: February 2014)

Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.

scientific article

The Expanding Landscape of the Thiol Redox Proteome

scientific article published on 30 October 2015

List of works by Kate Carroll

'Omics' of natural products and redox biology

3‘-Phosphoadenosine-5‘-phosphosulfate Reductase in Complex with Thioredoxin: A Structural Snapshot in the Catalytic Cycle † , ‡

A Chemical Approach for the Detection of Protein Sulfinylation.

A periplasmic reducing system protects single cysteine residues from oxidation

A universal entropy-driven mechanism for thioredoxin-target recognition

Activity of the tetrapyrrole regulator CrtJ is controlled by oxidation of a redox active cysteine located in the DNA binding domain.

Activity-Based Sensing for Site-Specific Proteomic Analysis of Cysteine Oxidation

An immunochemical approach to detect oxidized protein tyrosine phosphatases using a selective C-nucleophile tag

Call for Papers for the Special Issue on Natural Products in Redox Toxicology

Challenges in enzyme mechanism and energetics

Chemical approaches to discovery and study of sources and targets of hydrogen peroxide redox signaling through NADPH oxidase proteins

Chemical biology approaches to study protein cysteine sulfenylation.

Chemical proteomics reveals new targets of cysteine sulfinic acid reductase

Chemoselective ligation of sulfinic acids with aryl-nitroso compounds.

Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from <i>Mycobacterium tuberculosis</i>

Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery

DYn-2 Based Identification of Arabidopsis Sulfenomes.

Design, synthesis and evaluation of Fe-S targeted adenosine 5'-phosphosulfate reductase inhibitors.

Detection of protein S-sulfhydration by a tag-switch technique.

Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks

Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles

Efficient microwave-assisted solid phase coupling of nucleosides, small library generation and mild conditions for release of nucleoside derivatives

Empirical entropic contributions in computational docking: evaluation in APS reductase complexes.

Expanding the functional diversity of proteins through cysteine oxidation.

Facile synthesis and biological evaluation of a cell-permeable probe to detect redox-regulated proteins.

First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis

Functional Site Discovery in a Sulfur Metabolism Enzyme by Using Directed Evolution.

Geometric and electrostatic study of the [4Fe-4S] cluster of adenosine-5'-phosphosulfate reductase from broken symmetry density functional calculations and extended X-ray absorption fine structure spectroscopy.

Global, in situ, site-specific analysis of protein S-sulfenylation

Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase.

Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates

Investigation of the iron-sulfur cluster in Mycobacterium tuberculosis APS reductase: implications for substrate binding and catalysis

Iron-sulfur cluster engineering provides insight into the evolution of substrate specificity among sulfonucleotide reductases.

Isotope-coded chemical reporter and acid-cleavable affinity reagents for monitoring protein sulfenic acids

Light-Mediated Sulfenic Acid Generation from Photocaged Cysteine Sulfoxide

Metabolite imaging: knock, nox-ROS there?

Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase

Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice

New targets and inhibitors of mycobacterial sulfur metabolism.

Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity.

Persulfide reactivity in the detection of protein s-sulfhydration.

Probing the Tetrahymena group I ribozyme reaction in both directions.

Profiling protein thiol oxidation in tumor cells using sulfenic acid-specific antibodies.

Profiling the Reactivity of Cyclic C-Nucleophiles towards Electrophilic Sulfur in Cysteine Sulfenic Acid

Proteome-Wide Analysis of Cysteine S-Sulfenylation Using a Benzothiazine-Based Probe

Proteomic analysis of peptides tagged with dimedone and related probes

Quantification of protein sulfenic acid modifications using isotope-coded dimedone and iododimedone

Rab9 GTPase regulates late endosome size and requires effector interaction for its stability

Rational design of reversible and irreversible cysteine sulfenic acid-targeted linear C-nucleophiles.

Reactivity, Selectivity, and Stability in Sulfenic Acid Detection: A Comparative Study of Nucleophilic and Electrophilic Probes.

Redox Pathways in Chemical Toxicology

Redox-based probes as tools to monitor oxidized protein tyrosine phosphatases in living cells

Redox-based probes for protein tyrosine phosphatases

Reengineering redox sensitive GFP to measure mycothiol redox potential of Mycobacterium tuberculosis during infection

RegB kinase activity is repressed by oxidative formation of cysteine sulfenic acid.

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

Site-Specific Proteomic Mapping Identifies Selectively Modified Regulatory Cysteine Residues in Functionally Distinct Protein Networks

Site-specific mapping and quantification of protein S-sulphenylation in cells.

Spectroscopic studies on the [4Fe-4S] cluster in adenosine 5'-phosphosulfate reductase from Mycobacterium tuberculosis.

Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase.

Sulfenic acid chemistry, detection and cellular lifetime

Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.

The Expanding Landscape of the Thiol Redox Proteome