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List of works by Francesca Bruzzese

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells

scientific article published on 23 May 2013

Annexin A1 is involved in the acquisition and maintenance of a stem cell-like/aggressive phenotype in prostate cancer cells with acquired resistance to zoledronic acid.

scientific article published on 28 July 2015

HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT.

scientific article published on September 2011

Histone deacetylase inhibitors: a new wave of molecular targeted anticancer agents.

scientific article published on June 2007

Local and systemic protumorigenic effects of cancer-associated fibroblast-derived GDF15.

scientific article published on 29 April 2014

Multiple-target drugs: inhibitors of heat shock protein 90 and of histone deacetylase.

scientific article

New perspective for an old antidiabetic drug: metformin as anticancer agent.

scientific article

Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.

scientific article published on 24 October 2013

Pathophysiologically relevant in vitro tumor models for drug screening

scientific article published on 20 April 2015

Proteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep-2 cancer cells.

scientific article

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression.

scientific article published on 04 February 2016

Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression.

scientific article published on 31 December 2015

Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase.

scientific article

Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway

scientific article published on 24 September 2015